JP6932918B2 - Concentrated liquid denture cleanser composition, denture cleansing set and denture cleansing method - Google Patents

Description

The present invention is a concentrated liquid denture cleaning agent composition which is excellent in usability and dispersibility especially in denture cleaning using a washer and has an excellent cleaning effect of removing stain stains on the denture, and denture cleaning using the same. Regarding cleaning methods for sets and dentures.

Conventionally, the mainstream method for cleaning dentures is to put the dentures in water containing effervescent tablets or powdered denture detergent and immerse them overnight before going to bed.

In recent years, denture wearing patterns of denture wearers, especially those who wear partial dentures, have diversified, and the number of denture users who wear partial dentures only when necessary during the day or while sleeping is increasing. Such denture users often clean their dentures in the morning or before wearing them, or while brushing their remaining teeth, and there are denture cleaning means that can be cleaned in a shorter time than conventional overnight immersion. It has been demanded. As a preparation used for short-time washing, especially within 10 minutes, a liquid artificial dentist cleanser is more advantageous than a conventional tablet or powder which requires a time for the preparation to dissolve in water, and in this case, it is compact. Although it is effective to clean the artificial tooth using a simple cleaning device, there is still room for improvement in usability such as preventing the liquid artificial tooth cleaning agent from jumping out of the cleaning device.

On the other hand, stains adhering to dentures include denture plaque, food residues, stains (colored deposits), tartar and the like. In addition, since not only the teeth but also the palatal mucosa and the gingiva of the denture are made of resin or metal, the area to be soiled is large and the stains are easily noticeable. In particular, adhesion of stains to dentures is not preferable from the viewpoint of hygiene and aesthetics, and removal of stain stains is a major target of denture cleansers. It was difficult to satisfactorily remove the stain stains that had adhered firmly to the surface.

Patent Documents 1 to 3 (Japanese Patent Laid-Open Nos. 2008-179615, 2010-6720, and 2011-241167) contain specific surfactants, proteases, and the like, and are diluted with water. It has been proposed that the concentrated type liquid composition for cleaning dentures to be used has an excellent effect of removing denture biofilm and a bactericidal effect. A liquid denture detergent and a denture cleaning method containing phosphonic acid and excellent in bleaching and removing stains of tobacco tar have been proposed, but there is no mention of viscosity and the effect of removing stain stains is unknown. Further, Patent Documents 5 and 6 (Japanese Patent Laid-Open Nos. 2010-168352 and 2010-280588) contain a specific surfactant together with sulfites, and are liquids for cleaning dentures that exhibit stain stain removing power. Compositions have been proposed.

Japanese Unexamined Patent Publication No. 2008-179615 JP-A-2010-6720 Japanese Unexamined Patent Publication No. 2011-241167 Japanese Unexamined Patent Publication No. 6-183942 Japanese Unexamined Patent Publication No. 2010-168352 Japanese Unexamined Patent Publication No. 2010-280588

The present invention has been made in view of the above circumstances, and is a concentrated liquid denture cleaning agent which is particularly excellent in usability and dispersibility in denture cleaning using a washer and has an excellent cleaning effect of removing stain stains on the denture. It is an object of the present invention to provide a composition, a denture cleaning set using the composition, and a method for cleaning a denture.

As a result of diligent studies to achieve the above object, the present inventors have combined a surfactant and a thickener, particularly a specific surfactant and a thickener, in a concentrated liquid artificial tooth cleansing composition. When blended and set to a relatively low viscosity range for a concentrated type, it is particularly excellent in usability and dispersibility in cleaning artificial teeth using a washer, and it is also excellent in removing stain stains on artificial teeth during cleaning with a diluted cleaning liquid. It was found that it has a cleaning effect. That is, according to the present invention, the above-mentioned problem is caused by a concentrated liquid denture detergent composition containing (A) a surfactant and (B) a thickener and having a viscosity at 25 ° C. of 20 to 100 mPa · s. It was found that the above was achieved, and the present invention was made.

More specifically, the present invention is a concentrated liquid denture cleaning agent composition suitable for washing a denture by immersing the denture in the prepared cleaning liquid by pouring it into a washing machine together with water and diluting it, particularly using a washing machine. be. In this case, in order to use the liquid denture detergent composition and particularly to clean the denture within 15 minutes, moreover in a relatively short time of about 5 minutes, denture immersion using a cleaner is preferable, and in addition to this, denture immersion is preferable. It is more efficient to use ultrasonic waves, but denture cleaners, especially those for dentures, are smaller than ordinary multipurpose ultrasonic cleaners, so they are concentrated in the cleaning tank. When the liquid denture detergent composition is added, problems such as popping out of the cleaner and liquid splash are likely to occur, and in order to improve the above problems, the concentrated liquid denture detergent composition is imparted with viscosity. It was considered effective to do so. On the other hand, when diluting with water, it is also required to quickly uniformly disperse and dissolve in water even at low temperatures, but in order to improve usability, the viscosity of the concentrated liquid dentifrice detergent composition is increased. If it is added, the dispersibility in water deteriorates, so it was difficult to achieve both dispersibility. On the other hand, in the present invention, when the component (B) is mixed with the component (A) in the concentrated liquid denture cleansing composition and the viscosity is set in a specific range, it is surprisingly relatively low as a concentrated type. Within the range of viscosity, all of the above problems are solved, it is easy to put in a washer, it is possible to achieve both excellent usability and dispersibility that quickly disperses in cold water, and even if it is diluted and used, stain stains on the denture It was found that a high cleaning effect can be imparted, which can also be chemically removed.
In the present invention, a cleaning effect is given without blending a peroxide or the like generally used in a denture cleaning agent, and the cleaning effect is a stain strongly adhered to the denture surface, that is, mainly saliva protein. A thin film called a pellicle formed on the denture surface is modified by an external substance such as saliva or food, which is the oral environment, and removes strongly adhered stain stains, which is extremely excellent.

Therefore, the present invention provides the following concentrated liquid denture cleaning agent composition, denture cleaning set, and denture cleaning method.
[1]
A concentrated liquid denture cleansing composition containing (A) a surfactant and (B) a thickener and having a viscosity at 25 ° C. of 20 to 100 mPa · s.
[2]
(A) The concentrated liquid dentifrice detergent composition according to [1], wherein the surfactant is one or more selected from anionic surfactants and amphoteric surfactants.
[3]
(A) The surfactant is an alkyl sulfate having 8 to 18 carbon atoms, an α-olefin sulfonate having 8 to 18 carbon atoms, an acyl amino acid salt having an acyl group having 8 to 18 carbon atoms, and an alkyl group carbon. The concentrated liquid prosthesis cleaning composition according to [2], wherein the number is one or more selected from alkylamine oxides and coconut oil fatty acid amide propyl betaines having a number of 12 to 18.
[4]
(B) The concentrated liquid denture detergent composition according to any one of [1] to [3], wherein the thickener is an anionic water-soluble polymer compound.
[5]
The concentrated liquid dentifrice detergent composition according to [4], wherein the anionic water-soluble polymer compound is one or more selected from sodium alginate, sodium carboxymethyl cellulose and xanthan gum.
[6]
The concentrated liquid denture detergent composition according to any one of [1] to [5], which contains (A) a surfactant in an amount of 1 to 10% by mass and (B) a thickener in an amount of 0.1 to 5% by mass. ..
[7]
A concentrated liquid artificial tooth detergent composition that applies a cleaning solution diluted with water at the time of use to a prosthetic tooth, the dilution ratio with water is 10 to 100 times, and the surfactant (A) in the cleaning solution. The concentrated liquid dentifrice detergent composition according to any one of [1] to [6], which has a concentration of 0.1% by mass or more.
[8]
The concentrated liquid dentifrice cleaning agent composition according to any one of [1] to [7] is housed in a plastic bottle container having a flexible container body and a spout having a diameter of 5 mm or less. A prosthesis cleaning set consisting of a liquid prosthesis cleaning agent and a prosthesis cleaning device provided with a cleaning tank into which the liquid prosthesis cleaning agent is charged.
[9]
The denture cleaning set according to [8], wherein the cleaning tank of the denture cleaning device has a circular or elliptical shape having a diameter or major axis of 12 cm or less, or a quadrangular shape having at least one side of 12 cm or less.
[10]
The denture cleaning set according to [8] or [9], wherein the denture cleaning device is an ultrasonic cleaning device.
[11]
In the cleaning tank of the artificial tooth cleaning device, (A) a surfactant and (B) a thickener are mixed, and a concentrated liquid artificial tooth cleaning agent composition having a viscosity at 25 ° C. of 20 to 100 mPa · s and water are mixed. A method for cleaning a prosthesis, which comprises adding and diluting to prepare a cleaning liquid, and then immersing the prosthesis in the cleaning liquid for cleaning.
[12]
The method for cleaning a denture according to [11], wherein the dilution ratio with water is 10 to 100 times, and the concentration of the (A) surfactant in the cleaning liquid is 0.1% by mass or more.
[13]
The method for cleaning a denture according to [11] or [12], wherein the denture is cleaned by applying ultrasonic waves at the time of immersion.

According to the present invention, a concentrated liquid denture cleaning agent composition which is excellent in usability and dispersibility especially in denture cleaning using a washer and has an excellent cleaning effect of removing stain stains on the denture, is used. A denture cleaning set and a denture cleaning method can be provided.

Hereinafter, the present invention will be described in more detail. The "concentrated liquid artificial tooth cleaning agent composition" of the present invention is a liquid artificial tooth cleaning agent that serves as a stock solution for cleaning as a cleaning solution diluted with water at the time of cleaning the artificial tooth. The concentrated liquid denture cleansing composition of the present invention is characterized by containing (A) a surfactant and (B) a thickener and having a viscosity at 25 ° C. of 20 to 100 mPa · s. It is applied to dentures in liquid form (not foamy form) diluted with water at the time of use.

As the surfactant (A), any of an anionic surfactant, an amphoteric surfactant, a nonionic surfactant, and a cationic surfactant can be blended, but both of them are particularly effective in terms of detergency against stain stains. The surfactant alkylamine oxide, betaine-type amphoteric surfactant, and anionic surfactant are preferable, and alkylamine oxide and anionic surfactant are more preferable.
Specifically, examples of the anionic surfactant include an alkyl sulfate having 8 to 18 carbon atoms, an α-olefin sulfonate having 8 to 18 carbon atoms, an acyl amino acid salt having 8 to 18 carbon atoms in the acyl group, and an amphoteric interface. As the activator, an alkylamine oxide having an alkyl group having 12 to 18 carbon atoms and a betaine-type amphoteric surfactant are preferable from the viewpoint of detergency, and among them, an alkyl sulfate, an α-olefin sulfonate, and an acyl amino acid salt are preferable. , Alkylamine oxides, in particular, alkyldimethylamine oxides and acylglutamates are more preferable from the viewpoint of stain removing effect.

Examples of the alkyl sulfate include lauryl sulfate such as sodium lauryl sulfate, and commercially available products such as those manufactured by BASF can be used.

The α-olefin sulfonic acid salt preferably has 8 to 18 carbon atoms, particularly 14 to 16 carbon atoms, and for example, an alkali metal salt such as sodium or potassium of the α-olefin sulfonic acid having 14 to 16 carbon atoms may be used. can. Of these, an α-olefin sulfonate having 14 carbon atoms, particularly a sodium salt (generic name: sodium tetradecene sulfonate) is preferable.
Commercially available products that can be used for oral preparations are available. For example, the trade names "K Liporan PJ-400CJ (powder)" and "Liporan LB-440 (liquid) manufactured by Lion Specialty Chemicals Co., Ltd." ) ”Can be used.

The acyl amino acid salt preferably has an acyl group having 8 to 18 carbon atoms, particularly 12 to 16, and includes acyl glutamate, acyl aspartate, acyl sarcosine salt, acyl taurine salt and the like having an acyl group having such a carbon number. Can be mentioned. Among the acyl amino acids, acidic acyl amino acid salts, particularly acyl glutamate and acyl aspartate, particularly acyl glutamate are preferable. Specific examples thereof include lauroyl glutamate, myristoyl glutamate, lauroyl glutamate, lauroyl asparagate, lauroyl sarcosin salt, lauroyl methyl taurine salt and the like. As the salt, an alkali metal salt is preferable, and a sodium salt is particularly preferable. Specifically, a commercially available product manufactured by Asahi Kasei Chemicals Co., Ltd. can be used.

The alkylamine oxide preferably has an alkyl group having 12 to 18 carbon atoms, particularly 12 to 16 carbon atoms. Alkylamine oxides and alkyldimethylamine oxides having such an alkyl group having an alkyl number of carbon atoms can be used, and examples thereof include lauryldimethylamine oxide and the like. Specifically, a commercially available product such as the trade name "Cadenax DM12D-W" (lauryl dimethylamine oxide) manufactured by Lion Specialty Chemicals Co., Ltd. can be used.

Examples of the betaine-type amphoteric surfactant include 2-alkyl-N-carboxymethyl-N-hydroxyethyl imidazolinium betaine, fatty acid amide propyl betaine such as coconut oil fatty acid amide propyl betaine, and lauryl dimethylamino acetate betaine. Of these, 2-alkyl-N-carboxymethyl-N-hydroxyethyl imidazolinium betaine and fatty acid amide propyl betaine are preferable, and fatty acid amide propyl betaine is particularly preferable.
2-Alkyl-N-carboxymethyl-N-hydroxyethyl imidazolinium betaine is a 2-palm oil alkyl-N-carboxymethyl-N-hydroxy sold by Lion Co., Ltd. under the trade name Energycol C-40H. As the ethylimidazolinium betaine sodium aqueous solution and the fatty acid amide propyl betaine, TEGO BETAIN CK, which is a coconut oil fatty acid amide propyl betaine sold by Degussa, and the trade name manufactured by Sanyo Kasei Kogyo Co., Ltd .; Lebon 2000, etc. are used. be able to.

Examples of the cationic surfactant include quaternary ammonium salts of alkyl (6 to 20 carbon atoms), dialkyl (6 to 20 carbon atoms) dimethylammonium salt, and alkyl (6 to 20 carbon atoms) dimethylbenzylammonium salt. Examples thereof include ammonium salts, alkyl (6 to 20 carbon atoms) amine salts, alkyl (6 to 20 carbon atoms) amine ethylene oxide adducts, and alkyl pyridinium salts.
These surfactants may be used alone or in combination of two or more.

The blending amount of the surfactant (A) is preferably 1 to 10% (mass%, the same applies hereinafter) of the entire composition, and more preferably 3 to 10%. When it is 1% or more, it is advantageous in terms of detergency, particularly in terms of setting the dilution ratio at which the effect of removing stain stains can be sufficiently obtained, and when it is 10% or less, the storage stability of the formulation at low temperature is sufficiently excellent.

(B) As the thickener, a water-soluble polymer compound can be blended, but from the viewpoint of viscosity stability of the preparation, anionic water-soluble polymer compounds, particularly sodium alginate, sodium carboxymethyl cellulose, and xanthan gum are used. Among them, sodium alginate and sodium carboxymethyl cellulose are preferable from the viewpoint of viscosity stability and dispersibility of the preparation, particularly dispersibility by ultrasonic waves. These water-soluble polymer compounds may be used alone or in combination of two or more.
Depending on the polymer compound, the preparation may be aggregated and difficult to disperse even when ultrasonic waves are applied. However, in the present invention, the component (B), particularly the above-mentioned specific water-soluble polymer compound, is used. The viscosity can be adjusted without causing such aggregation and deterioration of dispersibility.

The amount of the thickener (B) to be blended can be appropriately set so that the viscosity range according to the present invention, that is, the viscosity at 25 ° C. is 20 to 100 mPa · s, but is usually the whole composition. It is preferably in the range of 0.1 to 5%, more preferably 0.1 to 1%, and even more preferably 0.2 to 0.6%. When the blending amount is 0.1% or more, sufficient and appropriate viscosity can be imparted. When it is 5% or less, the effect of the present invention can be obtained in a liquid form without the viscosity being too high or the dosage form becoming a paste or gel.

The concentrated liquid denture detergent composition of the present invention has a viscosity at 25 ° C. of 20 to 100 mPa · s, preferably 20 to 80 mPa. · S, more preferably 25-60 mPa · s. If the viscosity is less than 20 mPa · s, the ease of putting into the washer is inferior. If it exceeds 100 mPa · s, the dispersibility in cold water is poor, and even if ultrasonic cleaning is performed for 5 minutes, it does not disperse in water and remains undissolved. In the present invention, the viscosity was measured using a B-type viscometer (VISCOMETER TVB-10, manufactured by Toki Sangyo Co., Ltd.) (the same applies hereinafter).

In addition, it is preferable to further add a chelating agent, particularly hydroxyethanediphosphonic acid, to the composition of the present invention. When hydroxyethanediphosphonic acid is added, the effect of removing stain stains is further enhanced. The blending amount is preferably 0.5 to 10%, more preferably 3 to 10% of the entire composition.

In addition to the above components, other known components can be added to the concentrated liquid denture cleansing composition of the present invention, if necessary. For example, fragrances, solvents, colorants, bactericides and the like can be mentioned.

As fragrances, spare mint oil, peppermint oil, anis oil, eucalyptus oil, winter green oil, cassia oil, clove oil, thyme oil, sage oil, lemon oil, orange oil, peppermint oil, cardamon oil, coriander oil, mandarin oil, Natural fragrances such as lime oil, lavender oil, rosemary oil, laurel oil, camomill oil, caraway oil, majorum oil, bay oil, lemongrass oil, origanum oil, pine needle oil, cinnamon bark oil, and menthol, Menton, Carvone, Ethylbutyrate, Vanillin, Ethylmaltor, Anetol, Methyl salicylate, Synamicaldehyde, Cineol, Eugenol, Ethylvanillin, Martor, Limonen, Citronellol, Linarol, Linaryl acetate, Menthyl acetate, Pinen, Octylaldehyde, Citral , Pregon, Calvia Acetate, Anisaldehyde, Ginger Oleolezine, Creosol, dl-Camfer and other single fragrances, as well as Ethyl Acetate, Allyl Cyclohexane Propionate, Methyl Anthranilate, Ethyl Methylphenyl Glycydate, Undecalactone , Hexanal, ethyl alcohol, propyl alcohol, butanol, isoamyl alcohol and other single fragrances and / or various blended fragrances including natural fragrances, and other known fragrances used in oral preparations can be used in ordinary amounts.

Water (ion-exchanged water) is usually used as the solvent, but about 5 to 20% of polyhydric alcohol or the like can be added.

As colorants, Red No. 2, Red No. 3, Red No. 225, Red No. 226, Yellow No. 4, Yellow No. 5, Yellow No. 205, Blue No. 1, Blue No. 2, Blue No. 201, Blue No. 204, Green Legal dyes such as No. 3, caramel dye, Benibana dye, cutinashi dye, cochineal dye, annatto dye, mica titanium, titanium oxide and the like can be mentioned.

Examples of the disinfectant include nonionic disinfectants such as isopropylmethylphenol. The blending amount is an effective amount within a range that does not interfere with the effects of the present invention.

In the present invention, peroxides such as sodium percarbonate and sodium perborate, and oxidizing agents and bleaching agents such as hypochlorous acid or salts thereof and sulfites, which are generally used as components of artificial tooth cleansers, are particularly used. From the viewpoint of preventing deterioration of the artificial tooth, it is better not to mix (blending amount 0%). When blended, the blending amount of each is preferably 0.03% or less, particularly preferably 0.01% or less.

The concentrated liquid denture detergent composition of the present invention is a concentrated type preparation in which a cleaning liquid diluted with water is applied to a denture at the time of use, and is prepared as a concentrated denture detergent. In this case, the preferred dilution ratio with water is 10 to 100 times dilution, particularly 10 to 50 times dilution from the viewpoint of usability and solubility. Further, the concentration of the preferable component (A) of the diluted cleaning solution used when immersing the denture is 0.1% or more, particularly 0.15% or more, particularly 0.2% or more. The preferred pH (25 ° C.) of the diluted cleaning solution is 5-9, particularly 5.3-8. It is more preferable to design the amount and pH of the component (A) in the concentrated preparation so that all of these are within the above ranges, and appropriately set the dilution ratio.
The pH may be adjusted by adding a pH adjuster. Examples of the pH adjuster include sodium hydroxide, potassium hydroxide, hydrochloric acid, phosphoric acid or a salt thereof, citric acid or a salt thereof, sodium carbonate, sodium hydrogencarbonate, boric acid or a salt thereof and the like.

The concentrated liquid dentifrice detergent composition of the present invention can be stored in a generally known container for liquid preparations, but the storage container body is flexible and can be stored by pressing with a finger or the like from the outside. A container in which the contents (concentrated liquid artificial tooth cleaning agent composition) can be discharged from the main body and can be poured into a cleaning device is desirable, and a container having such a material and shape is preferable. For example, it is preferable to store the container in a plastic bottle container having a flexible main body with a spout portion having a diameter of 5 mm or less. In this case, the material of the container main body is PET (polyethylene terephthalate) or HDPE (high density). (Dense polyethylene) and the like are suitable. Further, the spout portion is a spout having a diameter of 5 mm or less, preferably 0.5 to 5 mm, and more preferably 1 to 3 mm, particularly from the viewpoint of ease of injection into the washer.

The concentrated liquid denture cleaning agent composition of the present invention is suitable for denture cleaning using a denture cleaning device, and a cleaning method in which the denture is immersed in the denture cleaning device after being diluted with water is preferably used. Can be adopted.
In this case, the denture washer may be any known one as long as it is provided with a cleaning tank in which the liquid preparation is put and the denture can be immersed and washed. In this case, the cleaning tank of the denture washer is not particularly limited as long as it has a size suitable for inserting the full denture or the partial denture of the denture, but if it is compact, it is preferable because it is easy to use (place). .. Specifically, a denture cleaner having a cleaning tank having a circular or elliptical shape having a diameter or major axis of 12 cm or less, or a square shape having at least one side of 12 cm or less makes it easy to put the concentrated liquid denture detergent composition. It is suitable from the viewpoint of usability. The capacity of the washing tank is preferably about 100 to 150 ml.
Further, the denture cleaner is preferably equipped with an ultrasonic device from the viewpoint of cleaning effect and efficiency, and an ultrasonic cleaner is preferable. The ultrasonic cleaning preferably has a frequency of 25 to 120 kHz, more preferably 40 to 100 kHz. When the ultrasonic frequency is at least the above lower limit value, the noise during cleaning is small, and the denture can be cleaned without any harm due to deformation or cracking. When the ultrasonic frequency is equal to or less than the upper limit value, high detergency can be obtained. The output is preferably 5 to 200 W, more preferably 10 to 100 W. If the ultrasonic output is equal to or higher than the lower limit, high detergency can be obtained. If the ultrasonic output is equal to or less than the upper limit, the denture can be cleaned without harm due to deformation or cracking.
In the denture cleaning using the above denture cleaning device, the denture immersion time is preferably 5 minutes or more, particularly preferably 10 minutes or more. The upper limit of the immersion time is not particularly limited, but is usually preferably within 8 hours, particularly preferably within 6 hours. Further, when ultrasonic cleaning is performed, it is preferably within 15 minutes, and particularly preferably about 5 minutes.

Hereinafter, the present invention will be specifically described with reference to Examples and Comparative Examples, but the present invention is not limited to the following Examples. Unless otherwise specified,% in the following examples indicates a mass percentage.

[Examples, comparative examples]
Concentrated liquid denture detergent compositions having the compositions shown in Tables 1 and 2 were prepared by a conventional method and evaluated by the methods shown in the following experimental examples. The results are also shown in the table.
The viscosity of the composition is a value measured under the following conditions.
-Viscometer: VISCOMETER TVB-10 (manufactured by Toki Sangyo Co., Ltd.)
・ Rotor No. : M1 (Example, Comparative Example 2), M2 (Comparative Examples 1, 3, 4)
・ Rotation speed: 50 rpm
・ Measurement time: 60 seconds

The main raw materials used are shown below.
(A) Lauryl dimethylamine oxide:
Made by Lion Specialty Chemicals Co., Ltd. (Product name: Cadenax DM12D-W)
(A) Sodium lauryl sulfate: manufactured by BASF (trade name: Texas OC-P)
(A) Sodium α-olefin sulfonate:
Made by Lion Specialty Chemicals Co., Ltd. (Product name: Liporan LB-440)
(A) Coconut oil fatty acid amide propyl betaine (30% aqueous solution):
Made by Sanyo Chemical Industries, Ltd. (Product name: Lebon 2000)
(B) Natrim alginate: Made by Kimika Co., Ltd. (Product name: Kimika Argin)
(B) Sodium Carboxymethyl Cellulose:
Made by Daicel Chemical Industry Co., Ltd. (degree of etherification: 0.87 to 0.92)
(B) Xanthan gum: Made by CP Kelco (Product name: Monato gum DA)

Experimental Example 1: Evaluation of usability (easiness to put in a washer) (1) Preparation of test sample The prepared concentrated liquid denture detergent composition was used as a sample.
(2) Usability evaluation method Evaluation was performed by a sensory test using 10 evaluators. A plastic bottle container body made of PET having an internal capacity of 250 ml was filled with about 250 ml of a sample, and the inlet of the bottle was sealed with a hinge cap having an inner diameter of 2 mm. Hold this plastic bottle container with one hand, remove the lid of the hinge cap, and pour about 5 g of the sample into the washing tank (circle with a diameter of about 7.5 cm and a depth of about 5 cm) of the washer from the spout with an inner diameter of 2 mm. The ease of insertion was evaluated according to the following evaluation criteria. Here, the ease of putting in means that when the container is put into the washing tank, it is prevented from jumping out of the container and the liquid splashes, and the surrounding area of the washing tank is not polluted, and the desired amount can be put into the washing tank accurately.
Evaluation criteria 4 points: Very easy to put in 3 points: Somewhat easy to put in 2 points: Somewhat difficult to put in 1 point: Very difficult to put in It was judged that the product to be prepared is a preparation that is easy to put in the washing tank of the washing machine and has good usability.
⊚: 3.5 points or more and 4.0 points or less ○: 3.0 points or more and less than 3.5 points Δ: 2.0 points or more and less than 3.0 points ×: less than 2.0 points

Experimental Example 2: Evaluation of dispersibility (1) Preparation of test sample To each of the prepared concentrated liquid denture detergent compositions, 0.001% of Blue No. 1 was further added to develop a blue color. Used as a sample.
(2) Evaluation method of dispersibility The blue-colored sample is stored in the same container as in Experimental Example 1, and about 5 g of the sample is poured into the washing tank (approximately circular shape with a diameter of 12 cm) of the ultrasonic cleaner in the same manner. After pouring 130 ml of cold water stored at 0 ° C., ultrasonic cleaning (frequency: 42 kHz, output: 17 W) was started, and the absorbance (630 nm) of the cleaning solution was measured 5 minutes after the start. A1). The sample was continued until it was completely dissolved in cold water, the absorbance in the dissolved state was measured (A0), the dispersion rate was obtained from the following formula, and the dispersibility was evaluated according to the following criteria.
Dispersion rate (%) = A1 / A0 × 100
Evaluation criteria ◎: Dispersion rate is 100%
◯: Dispersion rate is 90% or more and less than 100% Δ: Dispersion rate is 80% or more and less than 90% ×: Dispersion rate is less than 80%

Experimental Example 3-1: Evaluation of detergency <3-1> (1) Method for producing tannin iron stain-attached acrylic plate 1 Sandblast the surface of the acrylic plate (manufactured by Kuraray Co., Ltd., length 10 mm x width 10 mm x thickness 5 mm) After treatment with, it was washed with water in an ultrasonic cleaner (trade name: ultrasonic cleaner AU-80C, manufactured by Aiwa Medical Industry Co., Ltd.) containing a neutral detergent for 5 minutes. After repeating the cleaning treatment with the ultrasonic cleaner three times, it was naturally dried, and the Lab value (L0) of the acrylic plate before the tannin iron stain was attached was measured. The above acrylic plate was repeatedly immersed in the above acrylic plate in the order of 0.5% albumin aqueous solution → tannin extract → 0.6% ammonium iron (III) citrate aqueous solution for 30 minutes each, and at room temperature. After air-drying for one day, the mixture was washed with running water and air-dried again to prepare a colored acrylic plate 1.
The tannin extract is 50 g of Japanese tea (manufactured by Itoen Co., Ltd.), 5 bags of black tea (manufactured by Lipton, Brisk tea bag), and instant coffee (manufactured by Nestle, Nescafe) in 1,200 ml of boiled ion-exchanged water. 12 g was added and left overnight, and Japanese tea and black tea were removed by filtration to prepare the tea. The color of the surface of the produced colored acrylic plate 1 was measured, and the value was taken as the Lab value (L1).
(2) Preparation of test sample After preparing the concentrated liquid denture cleaning agent composition having the composition shown in Tables 1 and 2 by a conventional method, the cleaning liquid obtained by diluting each of them with ion-exchanged water 20 times was evaluated for detergency. Used as a sample.

(3) Evaluation Method of Tannin Iron Stain Removal Effect <3-1> Immerse the tannin iron stain-attached acrylic plate 1 prepared by the above method in a sample for 5 minutes, rinse it under running water, wash it, and then dry it. The Lab value (L2) of the acrylic plate 1 of No. 1 was measured. The tannin iron stain removal rate was calculated from the following formula.
Tannin iron stain removal rate (%) = [(L1-L2) / (L1-L0)] × 100
From the tannin iron stain removal rate, the stain detergency of the acrylic plate was evaluated according to the following criteria.
Evaluation criteria for detergency ◎: Tannin iron stain removal rate 60% or more ○: Tannin iron stain removal rate 50% or more and less than 60% Δ: Tannin iron stain removal rate 30% or more and less than 50% ×: Tannin iron stain removal rate 30% Less than

Experimental Example 3-2: Evaluation of detergency <3-2> (ultrasonic cleaning) (1) Method for producing acrylic plate 2 with tannin iron stain (deep stain stain) Acrylic plate surface (manufactured by Kuraray Co., Ltd., length 10 mm) After treating x 10 mm wide x 5 mm thick with sandblasting, put it in an ultrasonic cleaner (trade name: ultrasonic cleaner AU-80C, manufactured by Aiwa Medical Industry Co., Ltd.) containing a neutral detergent for 5 minutes. Rinse with water and wash. After repeating the cleaning treatment with the ultrasonic cleaner three times, it was naturally dried, and the Lab value (L0) of the acrylic plate before the tannin iron stain was attached was measured. The above acrylic plate was repeatedly immersed in the above acrylic plate in the order of 0.5% albumin aqueous solution → tannin extract → 0.6% iron (III) ammonium citrate aqueous solution for 30 minutes each, and repeated 10 times at room temperature. After air-drying for one day, the mixture was washed with running water and air-dried again to prepare a colored acrylic plate 2. The method for producing the tannin extract is the same as in Experimental Example 3-1.
The color of the surface of the produced colored acrylic plate 2 was measured, and the value was taken as the Lab value (L1).
(2) Preparation of test sample After preparing the concentrated liquid denture cleaning agent composition having the composition shown in Tables 1 and 2 by a conventional method, the cleaning liquid obtained by diluting each of them with ion-exchanged water 20 times was evaluated for detergency. Used as a sample.

(3) Evaluation method of tannin iron stain removing effect <3-2> After pouring about 130 ml of a cleaning power evaluation sample into the cleaning tank of an ultrasonic cleaner, the tannin iron stain-attached acrylic plate 2 produced by the above method is used. It was immersed and subjected to ultrasonic cleaning treatment (frequency: 42 kHz, output: 26 W) for 5 minutes. After the ultrasonic cleaning treatment, the acrylic plate was rinsed under running water and dried, and the Lab value (L2) of the acrylic plate was measured. The tannin iron stain removal rate was calculated from the following formula.
Tannin iron stain removal rate (%) = [(L1-L2) / (L1-L0)] × 100
From the tannin iron stain removal rate, the stain detergency of the acrylic plate was evaluated according to the following criteria.
Evaluation criteria for detergency ◎: Tannin iron stain removal rate 60% or more ○: Tannin iron stain removal rate 50% or more and less than 60% Δ: Tannin iron stain removal rate 30% or more and less than 50% ×: Tannin iron stain removal rate 30% Less than

＊；ヤシ油脂肪酸アミドプロピルベタインの純分量。

*; Pure amount of coconut oil fatty acid amide propyl betaine.

When the detergency was evaluated in the same manner as above except that the dilution ratio of the concentrated liquid denture detergent composition of Examples 1 and 14 was 30 times, the detergency <3-1> ◎, the detergency < 3-2> ◎.

Claims (13)

It contains (A) one or more surfactants selected from anionic surfactants and amphoteric surfactants , and (B) one or more thickeners selected from water-soluble polymer compounds. B) A concentrated liquid prosthesis detergent composition characterized in that the content of the component is 0.1 to 5% by mass and the viscosity at 25 ° C. is 20 to 100 mPa · s. (A) The surfactant is an alkyl sulfate having 8 to 18 carbon atoms, an α-olefin sulfonate having 8 to 18 carbon atoms, an acyl amino acid salt having an acyl group having 8 to 18 carbon atoms, and an alkyl group carbon. number alkylamine oxides and concentrative liquid denture cleansing composition according to claim 1, wherein those selected from coconut oil fatty acid amide propyl betaine is 12-18. The concentrated liquid artificial tooth detergent composition according to claim 1 or 2 , wherein the water-soluble polymer compound is an anionic water-soluble polymer compound. The concentrated liquid dentifrice detergent composition according to claim 3, wherein the anionic water-soluble polymer compound is one or more selected from sodium alginate, sodium carboxymethyl cellulose and xanthan gum. (A) The concentrated liquid denture detergent composition according to any one of claims 1 to 4 , which contains 1 to 10% by mass of a surfactant. A concentrated liquid artificial tooth detergent composition that applies a cleaning solution diluted with water at the time of use to a prosthetic tooth, the dilution ratio with water is 10 to 100 times, and the surfactant (A) in the cleaning solution. The concentrated liquid dentifrice detergent composition according to any one of claims 1 to 5 , wherein the concentration is 0.1% by mass or more. A liquid in which the concentrated liquid dentifrice cleaning agent composition according to any one of claims 1 to 6 is stored in a plastic bottle container having a flexible container body portion and a spout portion having a diameter of 5 mm or less. A prosthesis cleaning set consisting of a prosthesis cleaning agent and a prosthesis cleaning device provided with a cleaning tank into which the liquid prosthesis cleaning agent is charged. The denture cleaning set according to claim 7 , wherein the cleaning tank of the denture cleaning device has a circular or elliptical shape having a diameter or major axis of 12 cm or less, or a quadrangular shape having at least one side of 12 cm or less. The denture cleaning set according to claim 7 or 8 , wherein the denture cleaning device is an ultrasonic cleaning device. The cleaning tank denture cleaner, (A) an anionic surfactant and with one or more surfactants selected from amphoteric surfactants (B) one or more selected from water-soluble polymeric compound It blended with 0.1 to 5 wt% thickener, and diluted by introducing and water concentrative liquid denture cleaner composition the viscosity at 25 ° C. in 20~100mPa · s, to prepare a cleaning solution After that, a method for cleaning an artificial tooth, which comprises immersing the artificial tooth in the cleaning liquid for cleaning. (A) The method of cleaning dentures according to claim 10, wherein the surfactant blend 1 to 10 mass%. The method for cleaning a denture according to claim 10 or 11 , wherein the dilution ratio with water is 10 to 100 times, and the concentration of the (A) surfactant in the cleaning liquid is 0.1% by mass or more. The method for cleaning a denture according to any one of claims 10 to 12 , wherein the denture is cleaned by applying ultrasonic waves at the time of immersion.