JP6909917B1 - Emulsifying composition, oil-in-water (O / W type) emulsifying composition, and cosmetic composition - Google Patents
Emulsifying composition, oil-in-water (O / W type) emulsifying composition, and cosmetic composition Download PDFInfo
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- JP6909917B1 JP6909917B1 JP2020203220A JP2020203220A JP6909917B1 JP 6909917 B1 JP6909917 B1 JP 6909917B1 JP 2020203220 A JP2020203220 A JP 2020203220A JP 2020203220 A JP2020203220 A JP 2020203220A JP 6909917 B1 JP6909917 B1 JP 6909917B1
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Abstract
【課題】種々の油溶性物質を用いた場合でもエマルションの分散性が良好な乳化組成物を提供する。【解決手段】油溶性物質、多価アルコール、バイオマスナノファイバー、及び第1の水性媒体を含有し、前記油溶性物質の含有量が20質量%以上である乳化組成物であり、当該乳化組成物は、D相中油型(O/D型)であることが好ましい。【選択図】図1PROBLEM TO BE SOLVED: To provide an emulsified composition having good dispersibility of an emulsion even when various oil-soluble substances are used. An emulsified composition containing an oil-soluble substance, a polyhydric alcohol, biomass nanofibers, and a first aqueous medium, and the content of the oil-soluble substance is 20% by mass or more. Is preferably a D-phase medium oil type (O / D type). [Selection diagram] Fig. 1
Description
本発明は、乳化組成物、水中油型(O/W型)乳化組成物、及び化粧料組成物に関する。 The present invention relates to emulsified compositions, oil-in-water (O / W type) emulsified compositions, and cosmetic compositions.
加工食品、嗜好食品、健康食品といった各種食品、化粧品、医薬品、塗料、調理・調味料、各種飲料、飼料等の多くの製品において、乳化組成物(エマルション)が利用されている。これらの乳化組成物を含む製品では、品質の安定性を高めるために、油剤に対して安定な乳化能が求められる。乳化組成物の製造方法としては種々の方法が知られている。その中でも、微細な油滴の乳化組成物が得られるD(Detergent=界面活性剤)相乳化法が注目されている(例えば、特許文献1〜4参照)。 Emulsification compositions (emulsions) are used in many products such as processed foods, favorite foods, health foods, cosmetics, pharmaceuticals, paints, cooking / seasonings, various beverages, and feeds. Products containing these emulsifying compositions are required to have a stable emulsifying ability with respect to oils in order to improve quality stability. Various methods are known as methods for producing an emulsified composition. Among them, a D (Detergent) phase emulsification method for obtaining an emulsified composition of fine oil droplets has attracted attention (see, for example, Patent Documents 1 to 4).
D相乳化法は、まず乳化剤を多価アルコール又は多価アルコール水溶液に溶解し、これに油相を添加して乳化することにより乳化組成物を製造する。次いで、この乳化組成物を水性媒体で希釈することにより微細なエマルションを得る方法である(例えば、非特許文献1参照)。 In the D-phase emulsification method, an emulsifying composition is produced by first dissolving an emulsifier in a polyhydric alcohol or an aqueous solution of a polyhydric alcohol, adding an oil phase to the emulsifier, and emulsifying the emulsifier. Next, it is a method of obtaining a fine emulsion by diluting this emulsified composition with an aqueous medium (see, for example, Non-Patent Document 1).
例えば特許文献2には、D相中にHLBが6〜16の乳化剤を含むD相中油型(O/D型)乳化組成物に卵、酢及び油を加えて得られる水相中油型エマルション(マヨネーズ)が開示されている。そして、当該エマルションは、HLBが6〜16の乳化剤を卵、酢および油と単に混合して得られる水相中油型エマルション(マヨネーズ)よりも安定性が高いことが記載されている。特許文献4には、D相中にHLBが11〜16の乳化剤を含むD相中油型(O/D型)乳化組成物は、酸性食品中でも油滴が安定であることが記載されている。また、特許文献3の実施例2には、D相中にモノステアリン酸ジグリセリンエステル(HLB7.6)とジステアリン酸デカグリセリンエステル(HLB11.7)を含むD相中油型(O/D型)乳化組成物を含む全卵液は、冷凍しても安定であることが記載されている。 For example, Patent Document 2 describes an aqueous phase medium oil emulsion (O / D type) emulsion obtained by adding eggs, vinegar and oil to a D phase medium oil type (O / D type) emulsifying composition containing an emulsifier having an HLB of 6 to 16 in the D phase. Mayonnaise) is disclosed. It is described that the emulsion is more stable than the oil-in-phase oil-type emulsion (mayonnaise) obtained by simply mixing an emulsifier having an HLB of 6 to 16 with eggs, vinegar and oil. Patent Document 4 describes that the oil droplets of the D-phase medium oil type (O / D type) emulsified composition containing an emulsifier having an HLB of 11 to 16 in the D phase are stable even in an acidic food. Further, in Example 2 of Patent Document 3, a D-phase medium oil type (O / D type) containing monostearic acid diglycerin ester (HLB7.6) and distearic acid decaglycerin ester (HLB11.7) in the D phase. The whole egg solution containing the emulsified composition has been described as being stable even when frozen.
しかしながら、これらのD相中油型(O/D型)乳化組成物は、これを水性媒体と混合して得られる水相中油型(O/W型)エマルションの油滴の安定性、なかでも加温状態における油滴の安定性の点において、まだ満足すべきものとは言い難い。また、今後の製品の多様化に対応すべく、種々の油溶性物質に対して分散性の高い乳化組成物が得られれば汎用性の観点から好ましいが、そのような実用性の高い乳化組成物は未だ見出されていない。
そこで、本発明は、種々の油溶性物質を用いた場合でもエマルションの分散性が良好な乳化組成物を提供することを目的とする。
However, these D-phase medium oil type (O / D type) emulsified compositions add stability of oil droplets of an aqueous phase medium oil type (O / W type) emulsion obtained by mixing this with an aqueous medium. It is still far from satisfactory in terms of the stability of oil droplets in warm conditions. Further, in order to cope with the diversification of products in the future, it is preferable from the viewpoint of versatility that an emulsified composition having high dispersibility in various oil-soluble substances can be obtained, but such a highly practical emulsified composition Has not yet been found.
Therefore, an object of the present invention is to provide an emulsified composition having good dispersibility of an emulsion even when various oil-soluble substances are used.
本発明者らは、上記のような状況に鑑み鋭意検討した結果、高濃度の油溶性物質を含有させる際に、多価アルコールとバイオマスナノファイバーとを組み合わせることで、安定性が高い微細な油滴を与える乳化組成物が得られることを見出し、本発明を完成するに至った。すなわち、本発明は下記のとおりである。
[1] 多価アルコール、第1の水性媒体、バイオマスナノファイバー、及び油溶性物質を含有し、前記油溶性物質の含有量が20質量%以上である乳化組成物。
[2] D相中油型(O/D型)である[1]に記載の乳化組成物。
[3] 前記バイオマスナノファイバーがシルクナノファイバーである[1]又は[2]に記載の乳化組成物。
[4] 前記油溶性物質が飽和炭化水素系オイル及びシリコーン系オイルの少なくともいずれかである[1]〜[3]のいずれかに記載の乳化組成物。
[5] [1]〜[4]のいずれかに記載の乳化組成物と第2の水性媒体とを含有する水中油型(O/W型)乳化組成物。
[6] [1]〜[4]のいずれかに記載の乳化組成物、又は[5]に記載の水中油型(O/W型)乳化組成物を含む化粧料組成物。
As a result of diligent studies in view of the above circumstances, the present inventors have made a fine oil with high stability by combining a polyhydric alcohol and biomass nanofibers when containing a high concentration of oil-soluble substance. They have found that an emulsified composition that gives drops can be obtained, and have completed the present invention. That is, the present invention is as follows.
[1] An emulsified composition containing a polyhydric alcohol, a first aqueous medium, biomass nanofibers, and an oil-soluble substance, wherein the content of the oil-soluble substance is 20% by mass or more.
[2] The emulsified composition according to [1], which is a D-phase medium oil type (O / D type).
[3] The emulsified composition according to [1] or [2], wherein the biomass nanofibers are silk nanofibers.
[4] The emulsified composition according to any one of [1] to [3], wherein the oil-soluble substance is at least one of a saturated hydrocarbon oil and a silicone oil.
[5] An oil-in-water (O / W type) emulsified composition containing the emulsified composition according to any one of [1] to [4] and a second aqueous medium.
[6] A cosmetic composition containing the emulsified composition according to any one of [1] to [4] or the oil-in-water (O / W type) emulsified composition according to [5].
本発明によれば、種々の油溶性物質を用いた場合でもエマルションの分散性が良好な乳化組成物を提供することができる。
特に、本発明の乳化組成物がD相中油型(O/D型)乳化組成物である場合、水性媒体でさらに希釈した際に油滴の粒径が小さく安定性に優れたエマルションを与えるので、食品、医薬品、化粧品等の用途に好適に用いることができる。
According to the present invention, it is possible to provide an emulsified composition having good dispersibility of an emulsion even when various oil-soluble substances are used.
In particular, when the emulsified composition of the present invention is a D-phase medium oil type (O / D type) emulsified composition, when further diluted with an aqueous medium, an emulsion having a small particle size of oil droplets and excellent stability is obtained. , Foods, pharmaceuticals, cosmetics, etc. can be suitably used.
[乳化組成物]
本発明の実施形態に係る乳化組成物は、多価アルコール、第1の水性媒体、バイオマスナノファイバー、及び油溶性物質を含有し、上記油溶性物質の含有量が20質量%以上となっている。
[Emulsification composition]
The emulsified composition according to the embodiment of the present invention contains a polyhydric alcohol, a first aqueous medium, biomass nanofibers, and an oil-soluble substance, and the content of the oil-soluble substance is 20% by mass or more. ..
バイオマスナノファイバーとは、バイオマス由来のナノファイバーであり、植物ナノファイバー及び動物ナノファイバー等が挙げられる。これらはいずれもそのネットワーク中に親水部と疎水部とが存在する。この両親媒性に由来して、多価アルコールと水性媒体とがナノファイバーのネットワークに良好に保持された状態となり、20質量%以上という高濃度の油溶性物質の乳化安定性を向上させることができると推察される。
ここで、バイオマスナノファイバーの「ナノファイバー」とは、平均径(平均幅)が1nm〜1000nmのファイバーを意味する。
Biomass nanofibers are nanofibers derived from biomass, and examples thereof include plant nanofibers and animal nanofibers. All of these have a hydrophilic part and a hydrophobic part in the network. Due to this amphipathic nature, the polyhydric alcohol and the aqueous medium are well retained in the nanofiber network, and the emulsion stability of oil-soluble substances having a high concentration of 20% by mass or more can be improved. It is presumed that it can be done.
Here, the "nanofiber" of the biomass nanofiber means a fiber having an average diameter (average width) of 1 nm to 1000 nm.
本実施形態に係る乳化組成物は、バイオマスナノファイバーを含む多価アルコールと水性媒体、又は、バイオマスナノファイバーを含む多価アルコール水溶液に、油溶性物質を添加して攪拌することにより得ることができる。特に、バイオマスナノファイバーを含むことでそのネットワーク中の多価アルコールによって油溶性物質が補足されやすくなる。その結果、従来の乳化剤とは異なり、加温状態だけではなく室温にてエマルションの分散性が良好な乳化組成物が得られやすくなる。 The emulsified composition according to the present embodiment can be obtained by adding an oil-soluble substance to a polyhydric alcohol containing biomass nanofibers and an aqueous medium, or an aqueous solution of a polyhydric alcohol containing biomass nanofibers, and stirring the mixture. .. In particular, the inclusion of biomass nanofibers makes it easier for oil-soluble substances to be captured by the polyhydric alcohols in the network. As a result, unlike the conventional emulsifier, it becomes easy to obtain an emulsified composition having good dispersibility of the emulsion not only in the heated state but also at room temperature.
ここで、本実施形態に係る乳化組成物は、バイオマスナノファイバーのネットワーク中に油溶性物質を効率よく補足する観点から、D相中油型(O/D型)であることが好ましい。以下、各成分等について説明するが、本発明はこれらに限定されるものではない。 Here, the emulsified composition according to the present embodiment is preferably a D-phase medium oil type (O / D type) from the viewpoint of efficiently supplementing an oil-soluble substance in the network of biomass nanofibers. Hereinafter, each component and the like will be described, but the present invention is not limited thereto.
(多価アルコール)
多価アルコールは、水溶性多価アルコールが用いることが好ましく、なかでも分子内に水酸基を3個以上有するものが好ましい。例えば、グリセリン、ジグリセリン、トリグリセリン、テトラグリセリンなどのポリグリセリン、グルコース、マルトース、マルチトール、ショ糖、フラクトース、キシリトール、イノシトール、ペンタエリスリトール、ソルビトール、マルトトリオース、澱粉分解糖などの糖およびこれらの糖の還元アルコールなどが挙げられ、ポリグリセリンが好ましく、グリセリンがより好ましい。これらは、単独で用いても、2以上を組み合わせて使用してもよい。また、多価アルコールはそのまま用いても、水に溶解して50〜99.9質量%程度の水溶液として用いてもよい。
(Multivalent alcohol)
As the polyhydric alcohol, a water-soluble polyhydric alcohol is preferably used, and among them, those having three or more hydroxyl groups in the molecule are preferable. For example, polyglycerin such as glycerin, diglycerin, triglycerin, tetraglycerin, sugars such as glucose, maltose, martitol, sucrose, fructose, xylitol, inositol, pentaerythritol, sorbitol, maltotriose, starch-degrading sugar and these. Glycerin is preferable, and glycerin is more preferable. These may be used alone or in combination of two or more. Further, the polyhydric alcohol may be used as it is, or may be dissolved in water and used as an aqueous solution of about 50 to 99.9% by mass.
乳化組成物(特にD相中油型(O/D型)乳化組成物)に占める多価アルコールの割合は、7質量%以上であることが好ましく、15質量%以上であることがより好ましい。また、40質量%以下であることが好ましく、20質量%以下であることがより好ましい。 The proportion of the polyhydric alcohol in the emulsified composition (particularly the oil-type (O / D-type) emulsified composition in the D phase) is preferably 7% by mass or more, and more preferably 15% by mass or more. Further, it is preferably 40% by mass or less, and more preferably 20% by mass or less.
(第1の水性媒体)
第1の水性媒体としては、水や極性を有する有機溶媒等を含む水溶液等が挙げられ、有機溶媒の濃度が低いことが望ましく、特に水が好ましい。乳化組成物(特にD相中油型(O/D型)乳化組成物)に占める第1の水性媒体の割合は、1.0質量%以上であることが好ましく、1.5質量%以上であることがより好ましい。また、8.0質量%以下であることが好ましく、4.0質量%以下であることがより好ましい。
(First aqueous medium)
Examples of the first aqueous medium include water, an aqueous solution containing a polar organic solvent and the like, and it is desirable that the concentration of the organic solvent is low, and water is particularly preferable. The ratio of the first aqueous medium to the emulsified composition (particularly the oil-type (O / D-type) emulsified composition in the D phase) is preferably 1.0% by mass or more, preferably 1.5% by mass or more. Is more preferable. Further, it is preferably 8.0% by mass or less, and more preferably 4.0% by mass or less.
(バイオマスナノファイバー)
バイオマスナノファイバーは、乳化性能に優れており、種々の油溶性物質を用いた場合でも安定した乳化組成物を作ることができる。
バイオマスナノファイバーとしては、植物ナノファイバー及び動物ナノファイバー等が挙げられ、植物ナノファイバーとしては、セルロースナノファイバーが挙げられ、動物ナノファイバーとしては、シルクナノファイバー、キチンナノファイバー、キトサンナノファイバー等が挙げられる。
(Biomass nanofiber)
Biomass nanofibers are excellent in emulsification performance, and stable emulsification compositions can be produced even when various oil-soluble substances are used.
Examples of biomass nanofibers include plant nanofibers and animal nanofibers, examples of plant nanofibers include cellulose nanofibers, and examples of animal nanofibers include silk nanofibers, chitin nanofibers, and chitosan nanofibers. Can be mentioned.
ここで、セルロースナノファイバーとしては、結晶性セルロース由来のナノファイバー及び粉末セルロース由来のナノファイバーが好ましい。これらは、化学的安定性、熱的安定性の点で好ましい。
結晶性セルロース由来のナノファイバーとは、公知の結晶性セルロースを微細化処理し、ナノファイバー化したものをいう。本発明で使用する結晶性セルロースとは、繊維性植物からパルプとして得たα−セルロースを酸で部分的に解重合し、精製したものである。結晶性セルロースとしては、例えば、食品添加物公定書(第9版)に記載されたものが知られている。
Here, as the cellulose nanofibers, nanofibers derived from crystalline cellulose and nanofibers derived from powdered cellulose are preferable. These are preferable in terms of chemical stability and thermal stability.
The nanofibers derived from crystalline cellulose refer to those obtained by micronizing known crystalline cellulose into nanofibers. The crystalline cellulose used in the present invention is obtained by partially depolymerizing α-cellulose obtained as pulp from a fibrous plant with an acid and purifying it. As the crystalline cellulose, for example, those described in the Food Additives Official Standard (9th Edition) are known.
また、粉末セルロース由来のナノファイバーとは、公知の粉末セルロースを微細化処理し、ナノファイバー化したものをいう。本発明で使用する粉末セルロースとは、繊維性植物からパルプとして得たα−セルロースを処理した後、ヘミセルロース、リグニン等の非晶成分を残して精製し、機械的に粉砕したものである。粉末セルロースとしては、例えば、食品添加物公定書(第9版)に記載されたものが知られている。 Further, the nanofibers derived from powdered cellulose refer to those obtained by finely processing known powdered cellulose into nanofibers. The powdered cellulose used in the present invention is obtained by treating α-cellulose obtained as pulp from a fibrous plant, purifying it while leaving amorphous components such as hemicellulose and lignin, and mechanically pulverizing it. As the powdered cellulose, for example, those described in the Food Additives Official Standard (9th Edition) are known.
バイオマスナノファイバーは、その平均径が1〜1000nmである。平均径が1nm未満では、ナノファイバーのネットワーク構造が脆弱化し、構造保持することができなくなって、エマルションの不安定化を生じることがある。また、1000nmを超えると、サイズが大きくなりすぎてエマルションの安定性を阻害してしまうことがある。バイオマスナノファイバーの平均径は、10nm以上であることが好ましく、20nm以上であることがより好ましい。また、100nm以下であることが好ましく、50nm以下であることがより好ましい。 Biomass nanofibers have an average diameter of 1 to 1000 nm. If the average diameter is less than 1 nm, the network structure of the nanofibers becomes fragile, the structure cannot be maintained, and the emulsion may become unstable. On the other hand, if it exceeds 1000 nm, the size may become too large and the stability of the emulsion may be impaired. The average diameter of the biomass nanofibers is preferably 10 nm or more, more preferably 20 nm or more. Further, it is preferably 100 nm or less, and more preferably 50 nm or less.
バイオマスナノファイバーの平均長さは、1000nm以上であることが好ましく、2000nm以上であることがより好ましい。また、100μm以下であることが好ましく、50μm以下であることがより好ましい。
バイオマスナノファイバーの平均径、平均長さは、例えば、透過型電子顕微鏡観察により繊維の繊維径(繊維幅)及び長さをそれぞれ測定し、その平均値として求めることが可能である。
The average length of the biomass nanofibers is preferably 1000 nm or more, more preferably 2000 nm or more. Further, it is preferably 100 μm or less, and more preferably 50 μm or less.
The average diameter and average length of the biomass nanofibers can be obtained as the average value by measuring the fiber diameter (fiber width) and length of the fibers by, for example, observing with a transmission electron microscope.
また、バイオマスナノファイバーのアスペクト比(平均長さ/平均径)は、20〜10000であることが好ましく、40〜5000であることがより好ましく、100〜1000であることがより好ましい。 The aspect ratio (average length / average diameter) of the biomass nanofibers is preferably 20 to 10000, more preferably 40 to 5000, and even more preferably 100 to 1000.
また、バイオマスナノファイバーは、いずれも使用可能だが、化粧品用途を始めとした場合、生体への親和性を考慮すると、シルクナノファイバーや植物由来のナノファイバーであることが好ましい。 In addition, although any of the biomass nanofibers can be used, silk nanofibers and plant-derived nanofibers are preferable in consideration of the affinity for living organisms for cosmetic purposes.
シルクナノファイバーは、希薄なアルカリ薬剤を使用し、100〜245MPaの高圧噴射処理を行って、シルクナノファイバーを得たものを使用することが好ましい。このようなシルクナノファイバーは、アルカリ薬剤を使用しているが、化粧品原料や食品添加物で一般的に使用されている薬剤であり、また溶媒は水であること、シルク原料同志を衝突させることでナノファイバーの形状に解繊するため、不純物がナノファイバーの作製時に発生する可能性がより小さく、臼、砥石などのメディアを介し解繊するナノファイバーに対してより好ましい。
したがって、シルクナノファイバーは、高圧噴射処理を経て得られたものが好ましい。具体的には、当該シルクナノファイバーの結晶化度が3%以上であることが好ましく、10〜90%であることがより好ましい。
なお、結晶化度は、試料をガラスセルに乗せ、X線回折測定装置を用いて測定することで求めることができる。具体的には、X線回折図の2θ=5°〜60°の領域を測定することで、結晶部分と非晶部分(アモルファス)の回折強度が算出可能である。
As the silk nanofibers, it is preferable to use a dilute alkaline chemical and perform a high-pressure injection treatment of 100 to 245 MPa to obtain silk nanofibers. Although such silk nanofibers use alkaline chemicals, they are chemicals commonly used in cosmetic raw materials and food additives, the solvent is water, and the silk raw materials collide with each other. Since it is defibrated into the shape of nanofibers, impurities are less likely to be generated during the production of nanofibers, which is more preferable for nanofibers that are defibrated through a medium such as a mill or a grindstone.
Therefore, the silk nanofibers are preferably obtained through high-pressure injection treatment. Specifically, the crystallinity of the silk nanofibers is preferably 3% or more, more preferably 10 to 90%.
The crystallinity can be determined by placing the sample on a glass cell and measuring it using an X-ray diffraction measuring device. Specifically, the diffraction intensity of the crystalline portion and the amorphous portion (amorphous) can be calculated by measuring the region of 2θ = 5 ° to 60 ° in the X-ray diffraction diagram.
シルクナノファイバー以外のバイオナノマスファイバー、例えば、結晶性セルロース由来のナノファイバー、粉末セルロース由来のナノファイバー、キチンナノファイバー、キトサンナノファイバー等についても、例えば、直径0.1〜0.8mmの噴射ノズルを介して、100〜245MPaの高圧噴射処理により、バイオマス分散流体を衝突用硬質体に衝突させるか、または互いに噴射衝突させてバイオマスを微細化させて得られるものを使用することが好ましい。この方法は、市販されている高圧ホモジナイザーのように、分散流体を高圧低速で狭い流路を通過させ、解放時に均質化させるせん断力だけではなく、分散流体を衝突用硬質体に衝突させることによる衝突力や、キャビテーションを利用した、高圧での連続処理ができる。 For bio-nanomas fibers other than silk nanofibers, for example, nanofibers derived from crystalline cellulose, nanofibers derived from powdered cellulose, chitin nanofibers, chitosan nanofibers, etc., for example, an injection nozzle having a diameter of 0.1 to 0.8 mm. It is preferable to use a fluid obtained by colliding the biomass dispersion fluid with the collision hard body or injecting and colliding with each other to refine the biomass by a high-pressure injection treatment of 100 to 245 MPa. This method involves not only a shearing force that allows the dispersed fluid to pass through a narrow flow path at high pressure and low speed to homogenize it at the time of release, as in a commercially available high-pressure homogenizer, but also to cause the dispersed fluid to collide with a hard body for collision. Continuous processing at high pressure using collision force and cavitation is possible.
乳化組成物(特にD相中油型(O/D型)乳化組成物)に占めるバイオマスナノファイバーの割合は、水性媒体で希釈して水中油型(O/W型)エマルションとした際に油滴の粒子径を小さくする観点から、0.05質量%以上、好ましくは0.1質量%以上であり、また、エマルションの安定性の観点、及び食品や飲料に用いた場合の風味の観点から、10質量%以下、好ましくは5質量%以下である。 The proportion of biomass nanofibers in the emulsified composition (particularly the D-phase medium oil type (O / D type) emulsified composition) is oil droplets when diluted with an aqueous medium to form an oil-in-water (O / W type) emulsion. From the viewpoint of reducing the particle size of the emulsion, it is 0.05% by mass or more, preferably 0.1% by mass or more, and from the viewpoint of the stability of the emulsion and the flavor when used in foods and beverages. It is 10% by mass or less, preferably 5% by mass or less.
また、乳化組成物(特にD相中油型(O/D型)乳化組成物)において、バイオマスナノファイバーと油溶性物質との質量比(油溶性物質/バイオマスナノファイバー)は、エマルションの分散性とその安定性の観点から、50〜1000であることが好ましい。
特に、バイオマスナノファイバーがシルクナノファイバーである場合、上記の質量比は、100〜900であることがより好ましい。
また、バイオマスナノファイバーがキチンナノファイバー若しくはキトサンナノファイバーである場合、上記の質量比は、100〜450であることがより好ましく、100〜350であることがさらに好ましい。
さらに、バイオマスナノファイバーが結晶性セルロース由来のナノファイバーである場合、上記の質量比は、100〜450であることがより好ましく、100〜350であることがさらに好ましい。
また、バイオマスナノファイバーが粉末セルロース由来のナノファイバーである場合、上記の質量比は、100〜450であることがより好ましく、100〜350であることがさらに好ましい。
Further, in the emulsified composition (particularly the D-phase medium oil type (O / D type) emulsified composition), the mass ratio of the biomass nanofibers to the oil-soluble substance (oil-soluble substance / biomass nanofibers) is the dispersibility of the emulsion. From the viewpoint of its stability, it is preferably 50 to 1000.
In particular, when the biomass nanofibers are silk nanofibers, the mass ratio is more preferably 100 to 900.
When the biomass nanofibers are chitin nanofibers or chitosan nanofibers, the mass ratio is more preferably 100 to 450, and even more preferably 100 to 350.
Further, when the biomass nanofiber is a nanofiber derived from crystalline cellulose, the mass ratio is more preferably 100 to 450, and further preferably 100 to 350.
When the biomass nanofibers are nanofibers derived from powdered cellulose, the mass ratio is more preferably 100 to 450, and even more preferably 100 to 350.
(油溶性物質)
油溶性物質は、食品、飼料、化粧品、医薬品および工業等の分野で利用される任意の油溶性物質を用いることができ、例えば、脂肪酸、油脂、ワックス、炭化水素、シリコーン系オイル、高級アルコール、テルペン、精油、脂溶性ビタミン、油溶性薬物、油溶性色素等が挙げられる。
(Oil-soluble substance)
As the oil-soluble substance, any oil-soluble substance used in fields such as food, feed, cosmetics, pharmaceuticals and industry can be used, and for example, fatty acids, fats and oils, waxes, hydrocarbons, silicone-based oils, higher alcohols, etc. Examples include terpen, essential oils, fat-soluble vitamins, oil-soluble drugs, oil-soluble pigments and the like.
脂肪酸は、例えば、ミリスチン酸、パルミチン酸、イソパルミチン酸、ステアリン酸、オレイン酸、リノール酸、リノレン酸、リシノール酸、12−ヒドロキシステアリン酸、10−ヒドロキシステアリン酸、ベヘン酸、ヘキサデカトリエン酸、オクタデカトリエン酸、エイコサテトラエン酸、ドコサテトラエン酸、エイコサペンタエン酸、ドコサペンタエン酸、ドコサヘキサエン酸、テトラヘキサエン酸及びこれらの幾何異性体等が挙げられる。脂肪酸エステルは、ミリスチン酸エチル等上述の脂肪酸のエステル等が挙げられる。 Fatty acids include, for example, myristic acid, palmitic acid, isopalmitic acid, stearic acid, oleic acid, linolenic acid, linolenic acid, ricinoleic acid, 12-hydroxystearic acid, 10-hydroxystearic acid, behenic acid, hexadecatrine acid, Examples thereof include octadecatrienoic acid, eicosatetraenoic acid, docosapentaenoic acid, eicosapentaenoic acid, docosapentaenoic acid, docosapentaenoic acid, tetrahexaenoic acid, and geometric isomers thereof. Examples of the fatty acid ester include the above-mentioned fatty acid esters such as ethyl myristate.
油脂は、脂肪酸のグリセリンエステルであり、上述の脂肪酸混合物のグリセリンエステルである。例えば、魚油、牛脂、豚脂、乳脂、馬油、蛇油、卵油、卵黄油、タートル油、ミンク油などの動物性油脂類;大豆油、とうもろこし油、綿実油、なたね油、ごま油、シソ油、こめ油、ひまわり油、落花生油、オリーブ油、パーム油、パーム核油、米胚芽油、小麦胚芽油、玄米胚芽油、ハトムギ油、ガーリックオイル、マカデミアンナッツ油、アボガド油、月見草油、フラワー油、つばき油、やし油、ひまし油、あまに油、カカオ油などの植物性油脂類:およびこれらを水素添加またはエステル交換したもの;中鎖脂肪酸トリグリセライド等が挙げられる。 The fat and oil is a glycerin ester of a fatty acid, and is a glycerin ester of the above-mentioned fatty acid mixture. For example, animal fats and oils such as fish oil, beef fat, pork fat, milk fat, horse oil, snake oil, egg oil, egg yolk oil, turtle oil, mink oil; soybean oil, corn oil, cottonseed oil, rapeseed oil, sesame oil, perilla oil, Rice germ oil, sunflower oil, peanut oil, olive oil, palm oil, palm kernel oil, rice germ oil, wheat germ oil, brown rice germ oil, honeybee oil, garlic oil, macadamian nut oil, avocado oil, evening primrose oil, flower oil, Vegetable oils and fats such as brim oil, coconut oil, castor oil, linseed oil, and cacao oil: and hydrogenated or ester-exchanged ones; medium chain fatty acid triglyceride and the like.
ワックスは、脂肪酸と高級1価または2価アルコールとのエステルである。例えば、ホホバ油、ライスワックス、プロポリス、みつろう、さらしみつろう、キャンデリラワックス、カルナウバワックス、木ろう、鯨ろう等が挙げられる。 Wax is an ester of fatty acid and higher monohydric or divalent alcohol. For example, jojoba oil, rice wax, propolis, beeswax, bleached beeswax, candelilla wax, carnauba wax, wood wax, whale wax and the like can be mentioned.
炭化水素は、例えば、軽質流動パラフィン、重質流動パラフィン、流動イソパラフィン、軽質流動イソパラフィン等の流動パラフィン類、パラフィン、ワセリン、マイクロクリスタリンワックス、セレシン、スクワラン、スクワレン等が挙げられ、中でも、飽和炭化水素系オイルが好ましい。 Examples of hydrocarbons include liquid paraffins such as light liquid paraffin, heavy liquid paraffin, liquid isoparaffin, and light liquid isoparaffin, paraffin, petrolatum, microcrystalline wax, selecin, squalane, and squalene. Among them, saturated hydrocarbons. Squalene oil is preferable.
シリコーン系オイルは、例えば、ジメチルポリシロキサン、メチルフェニルポリシロキサン、環式シリコーン、ならびに、アミノシリコーン、脂肪酸シリコーン、アルコールシリコーン、ポリエーテルシリコーン、エポキシシリコーン、フッ素シリコーン、グリコシドシリコーンおよび/またはアルキルシリコーンを修飾したシリコーン化合物等が挙げられる。 Silicone-based oils modify, for example, dimethylpolysiloxane, methylphenylpolysiloxane, cyclic silicone, and aminosilicone, fatty acid silicone, alcohol silicone, polyether silicone, epoxy silicone, fluorosilicone, glycoside silicone and / or alkylsilicone. Examples thereof include silicone compounds.
高級アルコールは、例えば、ラウリルアルコール、ミリスチルアルコール、セタノール、ステアリルアルコール、オレイルアルコール、ラウリンアルコール、イソステアリルアルコール、2−オクチルドデカノールオクタコサノール等の炭素数8〜44の飽和または不飽和のアルコールが挙げられる。
テルペンは、例えば、オイゲノール、ゲラニオール、メントール、シトラール、シトロネラール、ボルネオール等が挙げられる。
Examples of higher alcohols include saturated or unsaturated alcohols having 8 to 44 carbon atoms such as lauryl alcohol, myristyl alcohol, cetanol, stearyl alcohol, oleyl alcohol, laurin alcohol, isostearyl alcohol and 2-octyldodecanol octacosanol. ..
Examples of terpenes include eugenol, geraniol, menthol, citral, citronellal, borneol and the like.
精油は、例えば、アンブレットシード油、カラシ油、サフラン油、シトロネラ油、ベチバー油、バレリアン油、ヨモギ油、カミツレ油、しょう脳油、サッサフラス油、ホウショウ油、ローズウッド油、クラリーセージ油、タイム油、バジル油、カーネーション油、シダーウッド油、ヒノキ油、ヒバ油、クローブ油、テレピン油、パイン油、オレンジ油、レモングラス油、タラゴン油、ローレル葉油、カシア油、シナモン油、コショウ油、カラムス油、セージ油、ハッカ油、ペパーミント油、スペアーミント油、パッチュリ油、ローズマリー油、ラバンジン油、ラベンダー油、クルクマ油、カルダモン油、ショウガ油、アンゲリカ油、アニス油、ウイキョウ油、パセリ油、セロリ油、カルバナム油、クミン油、コリアンダー油、ジル油、キャロット油、キラウェー油、ウィンターグリン油、ナツメグ油、ローズ油、シプレス油、ビャクダン油、オールスパイス油、グレープフルーツ油、ネロリ油、レモン油、ライム油、ベルガモット油、マンダリン油、オニオン油、ガーリック油、ビターアーモンド油、ゼラニウム油、ミモザ油、ジャスミン油、キンモクセイ油、スターアニス油、カナンガ油、イランイラン油、ユーカリ油等のエッセンシャルオイル;コショウ、ショウズク、ショウガ、パセリ、コリアンダー、ヒメウイキョウ、ピメンタ、バニラ、セロリ、チョウジ、ニクズク、パブリカ、イリスレジノイド、乳香樹等のオレオレジンまたはレジノイドが挙げられる。 Essential oils include, for example, ambrette seed oil, mustard oil, saffron oil, citronella oil, vetiver oil, valerian oil, yomogi oil, chamomile oil, sardine oil, sassafras oil, peppermint oil, rosewood oil, clary sage oil, thyme oil. , Basil oil, carnation oil, cedar wood oil, hinoki oil, hiba oil, clove oil, terepine oil, pine oil, orange oil, lemongrass oil, taragon oil, laurel leaf oil, cassia oil, cinnamon oil, pepper oil, columnar oil , Sage oil, peppermint oil, peppermint oil, spare mint oil, patchuri oil, rosemary oil, lavandine oil, lavender oil, curcuma oil, cardamon oil, ginger oil, angelica oil, anis oil, uikyo oil, parsley oil, celery oil , Carbanum oil, Cumin oil, Coriander oil, Jill oil, Carrot oil, Kiraway oil, Winter green oil, Natsumeg oil, Rose oil, Sipress oil, Byakudan oil, All spice oil, Grapefruit oil, Neroli oil, Lemon oil, Lime oil , Bergamot oil, mandarin oil, onion oil, garlic oil, bitter almond oil, geranium oil, mimosa oil, jasmine oil, kinmokusei oil, staranis oil, cananga oil, ylang ylang oil, eucalyptus oil and other essential oils; Examples thereof include oleoledin or resinoid such as ginger, parsley, coriander, himeuikyo, pimenta, vanilla, celery, chowji, nikuzuku, publica, iris resinoid, and milk scented tree.
脂溶性ビタミンは、例えば、ビタミンA、D、E、Kおよびこれらの誘導体が挙げられる。
油溶性薬物は、例えば、コエンザイムQ10、α−リポ酸、ルチン、ルテイン等が挙げられる。
油溶性色素は、例えば、アナトー色素、パプリカ色素、β−カロチン、クロロフィル、紅麹色素、ウコン色素等が挙げられる。これらは単独で用いても、2以上を組み合わせて用いても良い。
Fat-soluble vitamins include, for example, vitamins A, D, E, K and derivatives thereof.
Examples of the oil-soluble drug include coenzyme Q10, α-lipoic acid, rutin, lutein and the like.
Examples of the oil-soluble pigment include annatto pigment, paprika pigment, β-carotene, chlorophyll, red yeast pigment, turmeric pigment and the like. These may be used alone or in combination of two or more.
油溶性物質は、ナノファイバーのネットワーク中への良好な補足性の観点から、飽和炭化水素系オイル及びシリコーン系オイルの少なくともいずれかであることが好ましい。 The oil-soluble substance is preferably at least one of a saturated hydrocarbon-based oil and a silicone-based oil from the viewpoint of good catching property in the network of nanofibers.
なお、上記油溶性物質がD相中油型(O/D型)乳化組成物を製造する温度において固体の場合は、その温度において液体の油溶性物質に溶解させて用いればよい。 When the oil-soluble substance is solid at a temperature at which a D-phase medium oil type (O / D type) emulsified composition is produced, it may be dissolved in a liquid oil-soluble substance at that temperature before use.
乳化組成物(特にD相中油型(O/D型)乳化組成物)に占める油溶性物質の割合は、20質量%以上であり、30質量%以上が好ましく、40質量%以上がより好ましく、60質量%以上がさらに好ましい。20質量%未満であると、後の工程で水性媒体により希釈すると相対的に油溶性物質の濃度が低下し、汎用性も低下させてしまう。また、油溶性物質の割合は、90質量%以下であることが好ましく、80質量%以下であることがより好ましい。 The ratio of the oil-soluble substance in the emulsified composition (particularly the oil-type (O / D type) emulsified composition in the D phase) is 20% by mass or more, preferably 30% by mass or more, more preferably 40% by mass or more. More preferably, it is 60% by mass or more. If it is less than 20% by mass, the concentration of the oil-soluble substance is relatively lowered when diluted with an aqueous medium in a later step, and the versatility is also lowered. The proportion of the oil-soluble substance is preferably 90% by mass or less, and more preferably 80% by mass or less.
D相中油型(O/D型)乳化組成物は、バイオマスナノファイバーを分散した多価アルコールの水溶液を、10〜80℃の温度で、500〜20,000rpm、好ましくは1,000〜10,000rpmで攪拌し、この中に、親油性乳化剤を溶解した油溶性物質を少量ずつ添加した後、温度を保持したまま、500〜20,000rpm、好ましくは1,000〜10,000rpmで1〜60分間、好ましくは5〜30分間、さらに攪拌することにより得ることができる。 The D-phase medium oil type (O / D type) emulsifying composition is obtained by using an aqueous solution of a polyhydric alcohol in which biomass nanofibers are dispersed at a temperature of 10 to 80 ° C. at 500 to 20,000 rpm, preferably 1,000 to 10, The mixture is stirred at 000 rpm, and an oil-soluble substance in which a lipophilic emulsifier is dissolved is added little by little, and then the temperature is maintained at 500 to 20,000 rpm, preferably 1,000 to 10,000 rpm for 1 to 60. It can be obtained by further stirring for minutes, preferably 5 to 30 minutes.
(乳化剤)
本実施形態に係る乳化組成物には、乳化剤を含有させてもよい。使用可能な乳化剤としては、例えば、デカグリセリンモノミリステート、デカグリセリンモノパルミテート、デカグリセリンモノステアレート、デカグリセリンモノオレエートなどのグリセリンの重合度が4以上、好ましくは4〜12のポリグリセリン脂肪酸エステル;ショ糖モノミリスチン酸エステル、ショ糖モノパルミチン酸エステル、ショ糖モノステアリン酸エステル、ショ糖モノオレイン酸エステルなどのショ糖脂肪酸エステル;レシチン部分加水分解物、リゾレシチンなどの水溶性リン脂質;糖脂質;サポニン;大豆蛋白、カゼインナトリウムなどの蛋白質やその変性物といったHLBが10以上の乳化剤が挙げられる。これらは単独で用いても、2以上を組み合わせて使用してもよい。
(emulsifier)
The emulsified composition according to this embodiment may contain an emulsifier. Examples of the emulsifiers that can be used include polyglycerin having a degree of polymerization of glycerin of 4 or more, preferably 4 to 12, such as decaglycerin monomyristate, decaglycerin monopalmitate, decaglycerin monostearate, and decaglycerin monooleate. Fatty acid ester; sucrose fatty acid ester such as sucrose monomyristic acid ester, sucrose monopalmitic acid ester, sucrose monostearic acid ester, sucrose monooleic acid ester; sucrose partial hydrolyzate, water-soluble phospholipid such as lysolecithin Examples thereof include emulsifiers having an HLB of 10 or more, such as glycolipids; saponins; proteins such as soybean protein and sodium caseinate and modified products thereof. These may be used alone or in combination of two or more.
本実施形態に係る乳化組成物(特に、D相中油型(O/D型)乳化組成物)は、化粧品、塗料、医薬などやレトルト食品、インスタント食品、即席麺、ドライフーズ、加工乳などの加工食品や嗜好食品、サプリメント、機能性食品、特別用途食品、病者用食品、高齢者用食品、育児用粉ミルク、特定保健用食などの健康食品などの食品、自己乳化性油脂、ケチャップ、マヨネーズ、タルタルソース、ウスターソース、ラー油、香辛料、ハーブ、油脂、サラダドレッシングなどの調理・調味料、酒、コーヒー、茶などの飲料、に用いることができる。 The emulsified composition according to the present embodiment (particularly, D-phase medium oil type (O / D type) emulsified composition) includes cosmetics, paints, pharmaceuticals and the like, retort foods, instant foods, instant noodles, drifts, processed milk and the like. Foods such as processed foods, favorite foods, supplements, functional foods, special purpose foods, sick foods, elderly foods, childcare powdered milk, health foods such as specified health foods, self-emulsifying fats and oils, ketchup, mayonnaise , Tartar sauce, Worcester sauce, ra oil, spices, herbs, fats and oils, cooking / seasoning such as salad dressing, and beverages such as sake, coffee and tea.
[水中油型(O/W型)乳化組成物]
本発明の水中油型(O/W型)乳化組成物は、既述の本発明の乳化組成物と第2の水性媒体とを含有する。第2の水性媒体としては、第1の水性媒体と同様なものを例示でき、第1の水性媒体と第2の水性媒体とは同一でも異なっていてもよい。
[Oil-in-water type (O / W type) emulsified composition]
The oil-in-water (O / W type) emulsified composition of the present invention contains the above-mentioned emulsified composition of the present invention and a second aqueous medium. As the second aqueous medium, the same as the first aqueous medium can be exemplified, and the first aqueous medium and the second aqueous medium may be the same or different.
本発明に係るD相中油型(O/D型)乳化組成物は、D相中油型(O/D型)乳化組成物が0.01〜50質量%、好ましくは0.1〜20質量%となるように第2の水性媒体と混合することにより、水相中油型(O/W型)乳化組成物を与える。
本発明に係るD相中油型(O/D型)乳化組成物は、水溶性の有効成分や添加剤を加えたものを希釈して、化粧水や美容液等の化粧料組成物として利用することができる。また、本発明に係るD相中油型(O/D型)乳化組成物から得られる本発明の水中油型(O/W型)乳化組成物は、高温(60℃)での安定性も良好なので、即席スープなどの加熱用食品、ホットミルクコーヒー、ホットミルクティーなどの加温用飲料などにも好適に用いられる。
The D-phase medium oil type (O / D type) emulsified composition according to the present invention contains 0.01 to 50% by mass, preferably 0.1 to 20% by mass, of the D-phase medium oil type (O / D type) emulsified composition. By mixing with a second aqueous medium so as to be, an oil-in-phase (O / W type) emulsified composition is obtained.
The D-phase medium oil type (O / D type) emulsified composition according to the present invention is diluted with a water-soluble active ingredient or additive and used as a cosmetic composition such as a lotion or a beauty essence. be able to. Further, the oil-in-water (O / W type) emulsified composition of the present invention obtained from the D-phase medium oil type (O / D type) emulsified composition according to the present invention has good stability at a high temperature (60 ° C.). Therefore, it is suitably used for heating foods such as instant soup, and warming beverages such as hot milk coffee and hot milk tea.
[化粧料組成物]
本発明の化粧料組成物は、本発明の乳化組成物、又は本発明の水中油型(O/W型)乳化組成物を含む。そして、適宜、水溶性の有効成分や添加剤を加えたものを希釈して、化粧水や美容液等の化粧料組成物として利用することができる。
[Cosmetic composition]
The cosmetic composition of the present invention includes the emulsified composition of the present invention or the oil-in-water (O / W type) emulsified composition of the present invention. Then, a product to which a water-soluble active ingredient or additive is added can be appropriately diluted and used as a cosmetic composition such as a lotion or a beauty essence.
添加剤は、例えば、アスコルビン酸、ニコチン酸アミド、ニコチン酸等の水溶性ビタミン類;オウバクエキス、カンゾウエキス、アロエエキス、スギナエキス、茶エキス、キューカンバーエキス、チョウジエキス、ニンジンエキス、ハマメリス抽出液、プラセンタエキス、海藻エキス、マロニエエキス、ユズエキス、ユーカリエキス、アスナロ抽出液等の動・植物抽出液;水酸化カリウム、水酸化ナトリウム、トリエタノールアミン、炭酸ナトリウム等の塩類;クエン酸塩、酒石酸塩、乳酸塩、リン酸塩、コハク酸塩、アジピン酸塩等のpH調整剤;カルボキシビニルポリマー、アルギン酸ナトリウム、カラギーナン、カルボキシメチルセルロース、ヒドロキシエチルセルロース、グアーガム、キサンタンガム、カルボキシメチルキトサン、ヒアルロン酸ナトリウム等の増粘剤等が挙げられる。 Additives include, for example, water-soluble vitamins such as ascorbic acid, nicotinic acid amide, and nicotinic acid; Animal and plant extracts such as placenta extract, seaweed extract, marronnier extract, yuzu extract, eucalyptus extract, asunaro extract; salts such as potassium hydroxide, sodium hydroxide, triethanolamine, sodium carbonate; citrate, tartrate, PH adjusters such as lactate, phosphate, succinate, adipate; thickening of carboxyvinyl polymer, sodium alginate, carrageenan, carboxymethyl cellulose, hydroxyethyl cellulose, guar gum, xanthan gum, carboxymethyl chitosan, sodium hyaluronate, etc. Agents and the like can be mentioned.
以下、実施例を示し、本発明をさらに詳しく説明する。ただし、これらの実施例は、本発明を何ら限定もしくは制限するものでもない。
なお、各例における分散性は下記のとおりにして評価した。
Hereinafter, the present invention will be described in more detail with reference to Examples. However, these examples do not limit or limit the present invention in any way.
The dispersity in each example was evaluated as follows.
<分散安定性>
分散安定性(分散性)は、最終撹拌後に室温で静置し、72時間後の乳化組成物の外観の様子で評価を行った。「水層と油層の分離が明らかにあるもの」は×とし、「境界面が不鮮明な状態」を△、「分離が若干あるように見えるが、乳化状態にあるといえるもの」を△〇、明確な分離がほとんど確認できない、すなわち乳化状態にあるもの」を〇、明確な分離がまったく確認できない、すなわち非常に良好な乳化状態にあるもの」を◎とした。
<Dispersion stability>
The dispersion stability (dispersity) was evaluated by allowing the mixture to stand at room temperature after the final stirring and observing the appearance of the emulsified composition after 72 hours. "Those with clear separation between water layer and oil layer" are marked with x, "state where the boundary surface is unclear" is △, and "things that seem to have some separation but can be said to be in an emulsified state" are marked with △ 〇. "Those with almost no clear separation, that is, those in an emulsified state" were marked with 〇, and those with no clear separation, that is, those in a very good emulsified state, were marked with ◎.
<実施例1>
油溶性物質としてシリコーンオイル120gを使用して、以下の手順で乳化組成物(D相中油型(O/D型)乳化組成物)の作製を行った。
<Example 1>
Using 120 g of silicone oil as an oil-soluble substance, an emulsified composition (D phase medium oil type (O / D type) emulsified composition) was prepared by the following procedure.
(1)24gのグリセリン(富士フイルム和光純薬(株)製、以下の例も同様)に、シルクナノファイバー水分散体((株)スギノマシン製 高圧噴射処理品 シルクナノファイバー濃度5wt%、平均径100nm以下、以下のシルクナノファイバーの例も同様)とイオン交換水をそれぞれ3g添加して、撹拌を10分間行い、均一な混合体を作製した。
(2)スリーワンモーター撹拌機でシリコーンオイル(信越化学工業(株)製、製品名KF−96A−100CS、以下の例も同様)を(1)で作製した混合体に5ml/分の速度で添加した。
(3)添加終了後、300rpmで15分間攪拌し、D相中油型(O/D型)乳化組成物を得た。作製した乳化組成物について分散安定性の評価を行った。表1に乳化組成物中の各成分の割合(質量%)とともに評価結果とを示す。
(1) 24 g of glycerin (manufactured by Fujifilm Wako Pure Chemical Industries, Ltd., the same applies to the following examples), silk nanofiber aqueous dispersion (manufactured by Sugino Machine Co., Ltd., high-pressure injection processed product, silk nanofiber concentration 5 wt%, average 3 g of each of silk nanofibers having a diameter of 100 nm or less (the same applies to the following silk nanofiber examples) and ion-exchanged water were added, and the mixture was stirred for 10 minutes to prepare a uniform mixture.
(2) Silicone oil (manufactured by Shin-Etsu Chemical Co., Ltd., product name KF-96A-100CS, the same applies to the following examples) is added to the mixture prepared in (1) at a rate of 5 ml / min using a three-one motor stirrer. did.
(3) After completion of the addition, the mixture was stirred at 300 rpm for 15 minutes to obtain a D-phase medium oil type (O / D type) emulsified composition. The dispersion stability of the prepared emulsified composition was evaluated. Table 1 shows the evaluation results together with the ratio (mass%) of each component in the emulsified composition.
<実施例2>
油溶性物質として、シリコーンオイル120gを流動パラフィン(富士フイルム和光純薬(株)製、以下の例も同様)120gとした以外は実施例1と同様にして、D相中油型(O/D型)乳化組成物を作製し分散安定性の評価を行った。結果を表1に示す。
<Example 2>
D-phase medium oil type (O / D type) in the same manner as in Example 1 except that 120 g of silicone oil was used as an oil-soluble substance for liquid paraffin (manufactured by Fujifilm Wako Pure Chemical Industries, Ltd., the same applies to the following examples). ) An emulsified composition was prepared and the dispersion stability was evaluated. The results are shown in Table 1.
<実施例3>
油溶性物質として、シリコーンオイル120gをスクワラン(純正化学(株)製、以下の例も同様)120gとした以外は実施例1と同様にして、D相中油型(O/D型)乳化組成物を作製し分散安定性の評価を行った。結果を表1に示す。
<Example 3>
D-phase medium oil type (O / D type) emulsified composition in the same manner as in Example 1 except that 120 g of silicone oil was used as an oil-soluble substance in Squalane (manufactured by Junsei Chemical Co., Inc., the same applies to the following examples). Was prepared and the dispersion stability was evaluated. The results are shown in Table 1.
<実施例4>
油溶性物質として、シリコーンオイル120gをオリーブ油(富士フイルム和光純薬(株)製、以下の例も同様)120gとした以外は実施例1と同様にして、D相中油型(O/D型)乳化組成物を作製し分散安定性の評価を行った。結果を表1に示す。
<Example 4>
D-phase medium oil type (O / D type) in the same manner as in Example 1 except that 120 g of silicone oil was used as an oil-soluble substance as olive oil (manufactured by Fujifilm Wako Pure Chemical Industries, Ltd., the same applies to the following examples). An emulsified composition was prepared and the dispersion stability was evaluated. The results are shown in Table 1.
<実施例5>
油溶性物質として、シリコーンオイル120gをホホバ油(富士フイルム和光純薬(株)製、以下の例も同様)120gとした以外は実施例1と同様にして、D相中油型(O/D型)乳化組成物を作製し分散安定性の評価を行った。結果を表1に示す。
<Example 5>
D-phase medium oil type (O / D type) in the same manner as in Example 1 except that 120 g of silicone oil was used as an oil-soluble substance in jojoba oil (manufactured by Fujifilm Wako Pure Chemical Industries, Ltd., the same applies to the following examples). ) An emulsified composition was prepared and the dispersion stability was evaluated. The results are shown in Table 1.
<実施例6>
油溶性物質として、実施例1と同じシリコーンオイル120gを使用して、以下の手順で乳化組成物(D相中油型(O/D型)乳化組成物)の作製を行った。
(1)24gのグリセリンに実施例1使用したシルクナノファイバー水分散体を6g添加して、撹拌を10分間行い、均一な混合体を作製した。
(2)スリーワンモーター撹拌機でシリコーンオイルを(1)で作製した混合体に5ml/分の速度で添加した。
(3)添加終了後、300rpmで15分間撹拌し、D相中油型(O/D型)乳化組成物からなる自己乳化性油脂を得た。作製した乳化組成物について分散安定性の評価を行った。表1に乳化組成物中の各成分の割合(質量%)とともに評価結果とを示す。
<Example 6>
Using 120 g of the same silicone oil as in Example 1 as the oil-soluble substance, an emulsified composition (D phase medium oil type (O / D type) emulsified composition) was prepared by the following procedure.
(1) 6 g of the silk nanofiber aqueous dispersion used in Example 1 was added to 24 g of glycerin, and the mixture was stirred for 10 minutes to prepare a uniform mixture.
(2) Silicone oil was added to the mixture prepared in (1) at a rate of 5 ml / min with a three-one motor stirrer.
(3) After completion of the addition, the mixture was stirred at 300 rpm for 15 minutes to obtain a self-emulsifying fat and oil composed of a D-phase medium oil type (O / D type) emulsifying composition. The dispersion stability of the prepared emulsified composition was evaluated. Table 1 shows the evaluation results together with the ratio (mass%) of each component in the emulsified composition.
<実施例7>
(1)24gのグリセリンに、シルクナノファイバー水分散体を3gとイオン交換水を78g添加して、撹拌を10分間行い、均一な混合体を作製した。
(2)スリーワンモーター撹拌機でシリコーンオイルを(1)で作製した混合体に5ml/分の速度で45g添加した。
(3)添加終了後、300rpmで15分間攪拌し、D相中油型(O/D型)乳化組成物を得た。作製した乳化組成物について分散安定性の評価を行った。表1に乳化組成物中の各成分の割合(質量%)とともに評価結果とを示す。
<Example 7>
(1) To 24 g of glycerin, 3 g of an aqueous dispersion of silk nanofibers and 78 g of ion-exchanged water were added, and the mixture was stirred for 10 minutes to prepare a uniform mixture.
(2) With a three-one motor stirrer, 45 g of silicone oil was added to the mixture prepared in (1) at a rate of 5 ml / min.
(3) After completion of the addition, the mixture was stirred at 300 rpm for 15 minutes to obtain a D-phase medium oil type (O / D type) emulsified composition. The dispersion stability of the prepared emulsified composition was evaluated. Table 1 shows the evaluation results together with the ratio (mass%) of each component in the emulsified composition.
<実施例8>
(1)24gのグリセリン(富士フイルム和光純薬製)に、シルクナノファイバー水分散体を3gとイオン交換水を48g添加して、撹拌を10分間行い、均一な混合体を作製した。
(2)スリーワンモーター撹拌機でシリコーンオイルを(1)で作製した混合体に5ml/分の速度で75g添加した。
(3)添加終了後、300rpmで15分間攪拌し、D相中油型(O/D型)乳化組成物を得た。作製した乳化組成物について分散安定性の評価を行った。表1に乳化組成物中の各成分の割合(質量%)とともに評価結果とを示す。
<Example 8>
(1) To 24 g of glycerin (manufactured by Wako Pure Chemical Industries, Ltd.), 3 g of an aqueous dispersion of silk nanofibers and 48 g of ion-exchanged water were added, and the mixture was stirred for 10 minutes to prepare a uniform mixture.
(2) With a three-one motor stirrer, 75 g of silicone oil was added to the mixture prepared in (1) at a rate of 5 ml / min.
(3) After completion of the addition, the mixture was stirred at 300 rpm for 15 minutes to obtain a D-phase medium oil type (O / D type) emulsified composition. The dispersion stability of the prepared emulsified composition was evaluated. Table 1 shows the evaluation results together with the ratio (mass%) of each component in the emulsified composition.
<比較例1>
比較例1として、油溶性物質としてシリコーンオイル120gを使用して、以下の手順で乳化組成物(D相中油型(O/D型)乳化組成物)の作製を行った。
(1)24gのグリセリンにシルク粒子(平均粒径10〜40μm)とイオン交換水をそれぞれ3g添加して、撹拌を10分間行い、均一な混合体を作製した。
(2)スリーワンモーター撹拌機でシリコーンオイルを(1)で作製した混合体に5ml/分の速度で添加した。
(3)添加終了後、300rpmで15分間攪拌し、D相中油型(O/D型)乳化組成物からなる自己乳化性油脂を得た。作製した乳化組成物について分散安定性の評価を行った。表1に乳化組成物中の各成分の割合(質量%)とともに評価結果とを示す。
<Comparative example 1>
As Comparative Example 1, an emulsified composition (D phase medium oil type (O / D type) emulsified composition) was prepared by using 120 g of silicone oil as an oil-soluble substance by the following procedure.
(1) To 24 g of glycerin, 3 g of silk particles (average particle size 10 to 40 μm) and 3 g of ion-exchanged water were added, and the mixture was stirred for 10 minutes to prepare a uniform mixture.
(2) Silicone oil was added to the mixture prepared in (1) at a rate of 5 ml / min with a three-one motor stirrer.
(3) After completion of the addition, the mixture was stirred at 300 rpm for 15 minutes to obtain a self-emulsifying fat and oil composed of a D-phase medium oil type (O / D type) emulsifying composition. The dispersion stability of the prepared emulsified composition was evaluated. Table 1 shows the evaluation results together with the ratio (mass%) of each component in the emulsified composition.
<比較例2>
油溶性物質として、シリコーンオイル120gをスクワラン120gとした以外は比較例1と同様にして、D相中油型(O/D型)乳化組成物を作製し分散安定性の評価を行った。結果を表1に示す。
<Comparative example 2>
A D-phase medium oil type (O / D type) emulsified composition was prepared and the dispersion stability was evaluated in the same manner as in Comparative Example 1 except that 120 g of silicone oil was used as the oil-soluble substance and 120 g of squalane was used. The results are shown in Table 1.
<比較例3>
油溶性物質として、シリコーンオイル120gを流動パラフィン120gとした以外は比較例1と同様にして、D相中油型(O/D型)乳化組成物を作製し分散安定性の評価を行った。結果を表1に示す。
<Comparative example 3>
A D-phase medium oil type (O / D type) emulsified composition was prepared and the dispersion stability was evaluated in the same manner as in Comparative Example 1 except that 120 g of silicone oil was used as the oil-soluble substance and 120 g of liquid paraffin was used. The results are shown in Table 1.
<比較例4>
油溶性物質として、シリコーンオイル120gをオリーブ油120gとした以外は比較例1と同様にして、D相中油型(O/D型)乳化組成物を作製し分散安定性の評価を行った。結果を表1に示す。
<Comparative example 4>
A D-phase medium oil type (O / D type) emulsified composition was prepared and the dispersion stability was evaluated in the same manner as in Comparative Example 1 except that 120 g of silicone oil was used as the oil-soluble substance and 120 g of olive oil. The results are shown in Table 1.
<比較例5>
油溶性物質として、シリコーンオイル120gをホホバ油120gとした以外は比較例1と同様にして、D相中油型(O/D型)乳化組成物を作製し分散安定性の評価を行った。結果を表1に示す。
<Comparative example 5>
A D-phase medium oil type (O / D type) emulsified composition was prepared and the dispersion stability was evaluated in the same manner as in Comparative Example 1 except that 120 g of silicone oil was used as the oil-soluble substance and 120 g of jojoba oil was used. The results are shown in Table 1.
図1は、実施例1〜5である、シルクナノファイバーとシリコーンオイル、スクワラン、流動パラフィン、オリーブ油、ホホバ油のそれぞれとを撹拌して得られた乳化組成物を観察した画像であり、72時間後の乳化組成物の画像である。 FIG. 1 is an image of observing the emulsified composition obtained by stirring silk nanofibers and each of silicone oil, squalane, liquid paraffin, olive oil, and jojoba oil, which are Examples 1 to 5, for 72 hours. It is an image of the later emulsified composition.
図2は、比較例1〜5である、シルク粒子とシリコーンオイル、スクワラン、流動パラフィン、オリーブ油、ホホバ油のそれぞれとを撹拌して得られた乳化組成物を観察した画像であり、72時間後の乳化組成物の画像である。 FIG. 2 is an image of observing the emulsified composition obtained by stirring the silk particles and each of silicone oil, squalane, liquid paraffin, olive oil, and jojoba oil, which are Comparative Examples 1 to 5, after 72 hours. It is an image of the emulsified composition of.
図1と図2から次のことが判明した。本実施例の、シルクナノファイバーと多価アルコールを添加した乳化組成物に油剤を加えたものは、乳化状態を維持し、72時間後にも分離しなかった。その後も経過観察しているが、同様に乳化状態を維持していた。ナノファイバーに解繊されていないシルク粒子では、油層と水層がほぼ完全に分離した。 The following was found from FIGS. 1 and 2. In this example, the emulsified composition to which silk nanofibers and polyhydric alcohol were added to which an oil agent was added maintained an emulsified state and did not separate even after 72 hours. After that, the patient was followed up, but the emulsified state was maintained as well. In silk particles not defibrated into nanofibers, the oil layer and the aqueous layer were almost completely separated.
また、シルクナノファイバー濃度が0.1%(実施例1)、0.2%(実施例6)における粘度(25℃)を測定(レオメーターで72時間後)したところ、それぞれ、13000mPa・s、30000mPa・sであり、これらの粘度の比較から、乳化組成物の粘度は、ナノファイバーの濃度で制御することが可能であった。 Further, when the viscosity (25 ° C.) at a silk nanofiber concentration of 0.1% (Example 1) and 0.2% (Example 6) was measured (after 72 hours with a rheometer), 13000 mPa · s, respectively. , 30,000 mPa · s, and from the comparison of these viscosities, the viscosity of the emulsified composition could be controlled by the concentration of nanofibers.
本実施例によれば、シルクナノファイバーと多価アルコールを添加した乳化物を60℃で30分間加熱した後に放冷したものは、ほとんど変色せずに優れた乳化性能を長期に亘って維持することができるといえる。 According to this example, the emulsion to which silk nanofibers and polyhydric alcohol are added is heated at 60 ° C. for 30 minutes and then allowed to cool, and the emulsion maintains excellent emulsification performance for a long period of time with almost no discoloration. It can be said that it can be done.
<実施例9>
油溶性物質としてシリコーンオイル80gを使用して、以下の手順で乳化組成物(D相中油型(O/D型)乳化組成物)の作製を行った。
<Example 9>
Using 80 g of silicone oil as an oil-soluble substance, an emulsified composition (D phase medium oil type (O / D type) emulsified composition) was prepared by the following procedure.
(1)16gのグリセリンに、キチンナノファイバー水分散体((株)スギノマシン製 BiNFi−s(SFO−20010)、キチンナノファイバー濃度10wt%、平均径20〜50nm、以下のキチンナノファイバーの例も同様)とイオン交換水をそれぞれ2g添加して、撹拌を10分間行い、均一な混合体を作製した。
(2)スリーワンモーター撹拌機でシリコーンオイルを(1)で作製した混合体に5ml/分の速度で添加した。
(3)添加終了後、300rpmで15分間攪拌し、D相中油型(O/D型)乳化組成物を得た。作製した乳化組成物について分散安定性の評価を行った。表2に乳化組成物中の各成分の割合(質量%)とともに評価結果とを示す。
(1) Examples of the following chitin nanofibers in 16 g of glycerin, chitin nanofiber aqueous dispersion (BiNFi-s (SFO-40010) manufactured by Sugino Machine Co., Ltd., chitin nanofiber concentration 10 wt%, average diameter 20 to 50 nm). The same applies to the above) and 2 g of ion-exchanged water were added, and the mixture was stirred for 10 minutes to prepare a uniform mixture.
(2) Silicone oil was added to the mixture prepared in (1) at a rate of 5 ml / min with a three-one motor stirrer.
(3) After completion of the addition, the mixture was stirred at 300 rpm for 15 minutes to obtain a D-phase medium oil type (O / D type) emulsified composition. The dispersion stability of the prepared emulsified composition was evaluated. Table 2 shows the evaluation results together with the ratio (mass%) of each component in the emulsified composition.
<実施例10>
油溶性物質として、シリコーンオイル80gを流動パラフィン80gとした以外は実施例9と同様にして、D相中油型(O/D型)乳化組成物を作製し分散安定性の評価を行った。結果を表2に示す。
<Example 10>
A D-phase medium oil type (O / D type) emulsified composition was prepared and the dispersion stability was evaluated in the same manner as in Example 9 except that 80 g of silicone oil was used as the oil-soluble substance and 80 g of liquid paraffin was used. The results are shown in Table 2.
<実施例11>
油溶性物質として、シリコーンオイル80gをスクワラン80gとした以外は実施例9と同様にして、D相中油型(O/D型)乳化組成物を作製し分散安定性の評価を行った。結果を表2に示す。
<Example 11>
A D-phase medium oil type (O / D type) emulsified composition was prepared and the dispersion stability was evaluated in the same manner as in Example 9 except that 80 g of silicone oil was used as the oil-soluble substance and 80 g of squalane was used. The results are shown in Table 2.
<実施例12>
油溶性物質として、シリコーンオイル80gをオリーブ油80gとした以外は実施例9と同様にして、D相中油型(O/D型)乳化組成物を作製し分散安定性の評価を行った。結果を表2に示す。
<Example 12>
A D-phase medium oil type (O / D type) emulsified composition was prepared and the dispersion stability was evaluated in the same manner as in Example 9 except that 80 g of silicone oil was used as the oil-soluble substance and 80 g of olive oil. The results are shown in Table 2.
<実施例13>
油溶性物質として、シリコーンオイル80gをホホバ油80gとした以外は実施例9と同様にして、D相中油型(O/D型)乳化組成物を作製し分散安定性の評価を行った。結果を表2に示す。
<Example 13>
A D-phase medium oil type (O / D type) emulsified composition was prepared and the dispersion stability was evaluated in the same manner as in Example 9 except that 80 g of silicone oil was used as the oil-soluble substance and 80 g of jojoba oil was used. The results are shown in Table 2.
<実施例14>
油溶性物質として、実施例1と同じシリコーンオイル80gを使用して、以下の手順で乳化組成物(D相中油型(O/D型)乳化組成物)の作製を行った。
(1)16gのグリセリンに実施例9で使用したキチンナノファイバー水分散体を4g添加して、撹拌を10分間行い、均一な混合体を作製した。
(2)スリーワンモーター撹拌機でシリコーンオイルを(1)で作製した混合体に5ml/分の速度で添加した。
(3)添加終了後、300rpmで15分間撹拌し、D相中油型(O/D型)乳化組成物からなる自己乳化性油脂を得た。作製した乳化組成物について分散安定性の評価を行った。表2に乳化組成物中の各成分の割合(質量%)とともに評価結果とを示す。
<Example 14>
Using 80 g of the same silicone oil as in Example 1 as the oil-soluble substance, an emulsified composition (D phase medium oil type (O / D type) emulsified composition) was prepared by the following procedure.
(1) 4 g of the chitin nanofiber aqueous dispersion used in Example 9 was added to 16 g of glycerin, and the mixture was stirred for 10 minutes to prepare a uniform mixture.
(2) Silicone oil was added to the mixture prepared in (1) at a rate of 5 ml / min with a three-one motor stirrer.
(3) After completion of the addition, the mixture was stirred at 300 rpm for 15 minutes to obtain a self-emulsifying fat and oil composed of a D-phase medium oil type (O / D type) emulsifying composition. The dispersion stability of the prepared emulsified composition was evaluated. Table 2 shows the evaluation results together with the ratio (mass%) of each component in the emulsified composition.
<実施例15>
(1)16gのグリセリンに、キチンナノファイバー水分散体を2gとイオン交換水を52g添加して、撹拌を10分間行い、均一な混合体を作製した。
(2)スリーワンモーター撹拌機でシリコーンオイルを(1)で作製した混合体に5ml/分の速度で30g添加した。
(3)添加終了後、300rpmで15分間攪拌し、D相中油型(O/D型)乳化組成物を得た。作製した乳化組成物について分散安定性の評価を行った。表2に乳化組成物中の各成分の割合(質量%)とともに評価結果とを示す。
<Example 15>
(1) To 16 g of glycerin, 2 g of an aqueous dispersion of chitin nanofibers and 52 g of ion-exchanged water were added, and the mixture was stirred for 10 minutes to prepare a uniform mixture.
(2) With a three-one motor stirrer, 30 g of silicone oil was added to the mixture prepared in (1) at a rate of 5 ml / min.
(3) After completion of the addition, the mixture was stirred at 300 rpm for 15 minutes to obtain a D-phase medium oil type (O / D type) emulsified composition. The dispersion stability of the prepared emulsified composition was evaluated. Table 2 shows the evaluation results together with the ratio (mass%) of each component in the emulsified composition.
<実施例16>
(1)16gのグリセリン(富士フイルム和光純薬製)に、キチンナノファイバー水分散体を2gとイオン交換水を32g添加して、撹拌を10分間行い、均一な混合体を作製した。
(2)スリーワンモーター撹拌機でシリコーンオイルを(1)で作製した混合体に5ml/分の速度で50g添加した。
(3)添加終了後、300rpmで15分間攪拌し、D相中油型(O/D型)乳化組成物を得た。作製した乳化組成物について分散安定性の評価を行った。表2に乳化組成物中の各成分の割合(質量%)とともに評価結果とを示す。
<Example 16>
(1) To 16 g of glycerin (manufactured by Wako Pure Chemical Industries, Ltd.), 2 g of an aqueous dispersion of chitin nanofibers and 32 g of ion-exchanged water were added, and the mixture was stirred for 10 minutes to prepare a uniform mixture.
(2) 50 g of silicone oil was added to the mixture prepared in (1) at a rate of 5 ml / min with a three-one motor stirrer.
(3) After completion of the addition, the mixture was stirred at 300 rpm for 15 minutes to obtain a D-phase medium oil type (O / D type) emulsified composition. The dispersion stability of the prepared emulsified composition was evaluated. Table 2 shows the evaluation results together with the ratio (mass%) of each component in the emulsified composition.
<比較例6>
比較例6として、油溶性物質としてシリコーンオイル80gを使用して、以下の手順で乳化組成物(D相中油型(O/D型)乳化組成物)の作製を行った。
(1)16gのグリセリン(富士フイルム和光純薬製)にキチン粒子(平均粒径1〜300μm、アスペクト比(長径/短径)10未満)0.2gとイオン交換水を3.8g添加して、撹拌を10分間行い、均一な混合体を作製した。
(2)スリーワンモーター撹拌機でシリコーンオイルを(1)で作製した混合体に5ml/分の速度で添加した。
(3)添加終了後、300rpmで15分間攪拌し、D相中油型(O/D型)乳化組成物からなる自己乳化性油脂を得た。作製した乳化組成物について分散安定性の評価を行った。表2に乳化組成物中の各成分の割合(質量%)とともに評価結果とを示す。
<Comparative Example 6>
As Comparative Example 6, an emulsified composition (D phase medium oil type (O / D type) emulsified composition) was prepared by using 80 g of silicone oil as an oil-soluble substance by the following procedure.
(1) Add 0.2 g of chitin particles (average particle size 1 to 300 μm, aspect ratio (major axis / minor axis) less than 10) and 3.8 g of ion-exchanged water to 16 g of glycerin (manufactured by Fujifilm Wako Pure Chemical Industries, Ltd.). , Stirring was performed for 10 minutes to prepare a uniform mixture.
(2) Silicone oil was added to the mixture prepared in (1) at a rate of 5 ml / min with a three-one motor stirrer.
(3) After completion of the addition, the mixture was stirred at 300 rpm for 15 minutes to obtain a self-emulsifying fat and oil composed of a D-phase medium oil type (O / D type) emulsifying composition. The dispersion stability of the prepared emulsified composition was evaluated. Table 2 shows the evaluation results together with the ratio (mass%) of each component in the emulsified composition.
<比較例7>
油溶性物質として、シリコーンオイル80gを流動パラフィン80gとした以外は比較例6と同様にして、D相中油型(O/D型)乳化組成物を作製し分散安定性の評価を行った。結果を表2に示す。
<Comparative Example 7>
A D-phase medium oil type (O / D type) emulsified composition was prepared and the dispersion stability was evaluated in the same manner as in Comparative Example 6 except that 80 g of silicone oil was used as the oil-soluble substance and 80 g of liquid paraffin was used. The results are shown in Table 2.
<比較例8>
油溶性物質として、シリコーンオイル80gをスクワラン80gとした以外は比較例6と同様にして、D相中油型(O/D型)乳化組成物を作製し分散安定性の評価を行った。結果を表2に示す。
<Comparative Example 8>
A D-phase medium oil type (O / D type) emulsified composition was prepared and the dispersion stability was evaluated in the same manner as in Comparative Example 6 except that 80 g of silicone oil was used as the oil-soluble substance and 80 g of squalane was used. The results are shown in Table 2.
<比較例9>
油溶性物質として、シリコーンオイル80gをオリーブ油80gとした以外は比較例6と同様にして、D相中油型(O/D型)乳化組成物を作製し分散安定性の評価を行った。結果を表2に示す。
<Comparative Example 9>
A D-phase medium oil type (O / D type) emulsified composition was prepared and the dispersion stability was evaluated in the same manner as in Comparative Example 6 except that 80 g of silicone oil was used as the oil-soluble substance and 80 g of olive oil. The results are shown in Table 2.
<比較例10>
油溶性物質として、シリコーンオイル80gをホホバ油80gとした以外は比較例6と同様にして、D相中油型(O/D型)乳化組成物を作製し分散安定性の評価を行った。結果を表1に示す。
<Comparative Example 10>
A D-phase medium oil type (O / D type) emulsified composition was prepared and the dispersion stability was evaluated in the same manner as in Comparative Example 6 except that 80 g of silicone oil was used as the oil-soluble substance and 80 g of jojoba oil was used. The results are shown in Table 1.
図2は、実施例9〜13である、キチンナノファイバーとシリコーンオイル、流動パラフィン、スクワラン、オリーブ油、ホホバ油のそれぞれとを撹拌して得られた乳化組成物を観察した画像であり、72時間後の乳化組成物の画像である。 FIG. 2 is an image of observing the emulsified composition obtained by stirring chitin nanofibers and silicone oil, liquid paraffin, squalane, olive oil, and jojoba oil, which are Examples 9 to 13, for 72 hours. It is an image of the later emulsified composition.
<実施例17>
油溶性物質としてシリコーンオイル80gを使用して、以下の手順で乳化組成物(D相中油型(O/D型)乳化組成物)の作製を行った。
<Example 17>
Using 80 g of silicone oil as an oil-soluble substance, an emulsified composition (D phase medium oil type (O / D type) emulsified composition) was prepared by the following procedure.
(1)16gのグリセリンに、結晶性セルロース由来のナノファイバー水分散体((株)スギノマシン製BiNFi−s(AFO−10010)、結晶性セルロース由来のナノファイバー濃度10wt%、平均径20〜50nm、以下の結晶性セルロース由来のナノファイバーの例も同様)とイオン交換水をそれぞれ2g添加して、撹拌を10分間行い、均一な混合体を作製した。
(2)スリーワンモーター撹拌機でシリコーンオイルを(1)で作製した混合体に5ml/分の速度で添加した。
(3)添加終了後、300rpmで15分間攪拌し、D相中油型(O/D型)乳化組成物を得た。作製した乳化組成物について分散安定性の評価を行った。表3に乳化組成物中の各成分の割合(質量%)とともに評価結果とを示す。
(1) 16 g of glycerin, an aqueous dispersion of nanofibers derived from crystalline cellulose (BiNFi-s (AFO-10010) manufactured by Sugino Machine Co., Ltd., nanofiber concentration derived from crystalline cellulose 10 wt%, average diameter 20 to 50 nm , The same applies to the following examples of nanofibers derived from crystalline cellulose) and 2 g of ion-exchanged water were added, and the mixture was stirred for 10 minutes to prepare a uniform mixture.
(2) Silicone oil was added to the mixture prepared in (1) at a rate of 5 ml / min with a three-one motor stirrer.
(3) After completion of the addition, the mixture was stirred at 300 rpm for 15 minutes to obtain a D-phase medium oil type (O / D type) emulsified composition. The dispersion stability of the prepared emulsified composition was evaluated. Table 3 shows the evaluation results together with the ratio (mass%) of each component in the emulsified composition.
<実施例18>
油溶性物質として、シリコーンオイル80gを流動パラフィン80gとした以外は実施例17と同様にして、D相中油型(O/D型)乳化組成物を作製し分散安定性の評価を行った。結果を表3に示す。
<Example 18>
A D-phase medium oil type (O / D type) emulsified composition was prepared in the same manner as in Example 17 except that 80 g of silicone oil was used as the oil-soluble substance and 80 g of liquid paraffin was used, and the dispersion stability was evaluated. The results are shown in Table 3.
<実施例19>
油溶性物質として、シリコーンオイル80gをスクワラン80gとした以外は実施例17と同様にして、D相中油型(O/D型)乳化組成物を作製し分散安定性の評価を行った。結果を表3に示す。
<Example 19>
A D-phase medium oil type (O / D type) emulsified composition was prepared and the dispersion stability was evaluated in the same manner as in Example 17 except that 80 g of silicone oil was used as the oil-soluble substance and 80 g of squalane was used. The results are shown in Table 3.
<実施例20>
油溶性物質として、シリコーンオイル80gをオリーブ油80gとした以外は実施例17と同様にして、D相中油型(O/D型)乳化組成物を作製し分散安定性の評価を行った。結果を表3に示す。
<Example 20>
A D-phase medium oil type (O / D type) emulsified composition was prepared and the dispersion stability was evaluated in the same manner as in Example 17 except that 80 g of silicone oil was used as the oil-soluble substance and 80 g of olive oil. The results are shown in Table 3.
<実施例21>
油溶性物質として、シリコーンオイル80gをホホバ油80gとした以外は実施例17と同様にして、D相中油型(O/D型)乳化組成物を作製し分散安定性の評価を行った。結果を表3に示す。
<Example 21>
A D-phase medium oil type (O / D type) emulsified composition was prepared in the same manner as in Example 17 except that 80 g of silicone oil was used as the oil-soluble substance and 80 g of jojoba oil was used, and the dispersion stability was evaluated. The results are shown in Table 3.
<比較例11>
比較例11として、油溶性物質としてシリコーンオイル80gを使用して、以下の手順で乳化組成物(D相中油型(O/D型)乳化組成物)の作製を行った。
(1)16gのグリセリン(富士フイルム和光純薬製)に結晶性セルロース粒子(平均粒径10〜250μm、アスペクト比(長径/短径)10未満)を0.2gとイオン交換水を3.8g添加して、撹拌を10分間行い、均一な混合体を作製した。
(2)スリーワンモーター撹拌機でシリコーンオイルを(1)で作製した混合体に5ml/分の速度で添加した。
(3)添加終了後、300rpmで15分間攪拌し、D相中油型(O/D型)乳化組成物からなる自己乳化性油脂を得た。作製した乳化組成物について分散安定性の評価を行った。表3に乳化組成物中の各成分の割合(質量%)とともに評価結果とを示す。
<Comparative Example 11>
As Comparative Example 11, using 80 g of silicone oil as an oil-soluble substance, an emulsified composition (D phase medium oil type (O / D type) emulsified composition) was prepared by the following procedure.
(1) 16 g of glycerin (manufactured by Wako Pure Chemical Industries, Ltd.), 0.2 g of crystalline cellulose particles (average particle size 10 to 250 μm, aspect ratio (major axis / minor axis) less than 10) and 3.8 g of ion-exchanged water. Addition and stirring were carried out for 10 minutes to prepare a uniform mixture.
(2) Silicone oil was added to the mixture prepared in (1) at a rate of 5 ml / min with a three-one motor stirrer.
(3) After completion of the addition, the mixture was stirred at 300 rpm for 15 minutes to obtain a self-emulsifying fat and oil composed of a D-phase medium oil type (O / D type) emulsifying composition. The dispersion stability of the prepared emulsified composition was evaluated. Table 3 shows the evaluation results together with the ratio (mass%) of each component in the emulsified composition.
<比較例12>
油溶性物質として、シリコーンオイル80gを流動パラフィン80gとした以外は比較例11と同様にして、D相中油型(O/D型)乳化組成物を作製し分散安定性の評価を行った。結果を表3に示す。
<Comparative Example 12>
A D-phase medium oil type (O / D type) emulsified composition was prepared and the dispersion stability was evaluated in the same manner as in Comparative Example 11 except that 80 g of silicone oil was used as the oil-soluble substance and 80 g of liquid paraffin was used. The results are shown in Table 3.
<比較例13>
油溶性物質として、シリコーンオイル80gをスクワラン80gとした以外は比較例11と同様にして、D相中油型(O/D型)乳化組成物を作製し分散安定性の評価を行った。結果を表3に示す。
<Comparative Example 13>
A D-phase medium oil type (O / D type) emulsified composition was prepared and the dispersion stability was evaluated in the same manner as in Comparative Example 11 except that 80 g of silicone oil was used as the oil-soluble substance and 80 g of squalane was used. The results are shown in Table 3.
<比較例14>
油溶性物質として、シリコーンオイル80gをオリーブ油80gとした以外は比較例11と同様にして、D相中油型(O/D型)乳化組成物を作製し分散安定性の評価を行った。結果を表3に示す。
<Comparative Example 14>
A D-phase medium oil type (O / D type) emulsified composition was prepared and the dispersion stability was evaluated in the same manner as in Comparative Example 11 except that 80 g of silicone oil was used as the oil-soluble substance and 80 g of olive oil. The results are shown in Table 3.
<比較例15>
油溶性物質として、シリコーンオイル80gをホホバ油80gとした以外は比較例11と同様にして、D相中油型(O/D型)乳化組成物を作製し分散安定性の評価を行った。結果を表3に示す。
<Comparative Example 15>
A D-phase medium oil type (O / D type) emulsified composition was prepared and the dispersion stability was evaluated in the same manner as in Comparative Example 11 except that 80 g of silicone oil was used as the oil-soluble substance and 80 g of jojoba oil was used. The results are shown in Table 3.
<実施例22>
油溶性物質として、実施例17と同じシリコーンオイル80gを使用して、以下の手順で乳化組成物(D相中油型(O/D型)乳化組成物)の作製を行った。
(1)16gのグリセリンに実施例17で使用した結晶性セルロース由来のナノファイバー水分散体を3gとイオン交換水を1g添加して、撹拌を10分間行い、均一な混合体を作製した。
(2)スリーワンモーター撹拌機でシリコーンオイルを(1)で作製した混合体に5ml/分の速度で添加した。
(3)添加終了後、300rpmで15分間撹拌し、D相中油型(O/D型)乳化組成物からなる自己乳化性油脂を得た。作製した乳化組成物について分散安定性の評価を行った。表3に乳化組成物中の各成分の割合(質量%)とともに評価結果とを示す。
<Example 22>
Using 80 g of the same silicone oil as in Example 17 as the oil-soluble substance, an emulsified composition (D phase medium oil type (O / D type) emulsified composition) was prepared by the following procedure.
(1) To 16 g of glycerin, 3 g of the crystalline cellulose-derived nanofiber aqueous dispersion used in Example 17 and 1 g of ion-exchanged water were added, and the mixture was stirred for 10 minutes to prepare a uniform mixture.
(2) Silicone oil was added to the mixture prepared in (1) at a rate of 5 ml / min with a three-one motor stirrer.
(3) After completion of the addition, the mixture was stirred at 300 rpm for 15 minutes to obtain a self-emulsifying fat and oil composed of a D-phase medium oil type (O / D type) emulsifying composition. The dispersion stability of the prepared emulsified composition was evaluated. Table 3 shows the evaluation results together with the ratio (mass%) of each component in the emulsified composition.
<実施例23>
(1)16gのグリセリンに、結晶性セルロース由来のナノファイバー水分散体を2gとイオン交換水を52g添加して、撹拌を10分間行い、均一な混合体を作製した。
(2)スリーワンモーター撹拌機でシリコーンオイルを(1)で作製した混合体に5ml/分の速度で30g添加した。
(3)添加終了後、300rpmで15分間攪拌し、D相中油型(O/D型)乳化組成物を得た。作製した乳化組成物について分散安定性の評価を行った。表3に乳化組成物中の各成分の割合(質量%)とともに評価結果とを示す。
<Example 23>
(1) To 16 g of glycerin, 2 g of an aqueous dispersion of nanofibers derived from crystalline cellulose and 52 g of ion-exchanged water were added, and the mixture was stirred for 10 minutes to prepare a uniform mixture.
(2) With a three-one motor stirrer, 30 g of silicone oil was added to the mixture prepared in (1) at a rate of 5 ml / min.
(3) After completion of the addition, the mixture was stirred at 300 rpm for 15 minutes to obtain a D-phase medium oil type (O / D type) emulsified composition. The dispersion stability of the prepared emulsified composition was evaluated. Table 3 shows the evaluation results together with the ratio (mass%) of each component in the emulsified composition.
<実施例24>
(1)16gのグリセリン(富士フイルム和光純薬製)に、結晶性セルロース由来のナノファイバー水分散体を2gとイオン交換水を32g添加して、撹拌を10分間行い、均一な混合体を作製した。
(2)スリーワンモーター撹拌機でシリコーンオイルを(1)で作製した混合体に5ml/分の速度で50g添加した。
(3)添加終了後、300rpmで15分間攪拌し、D相中油型(O/D型)乳化組成物を得た。作製した乳化組成物について分散安定性の評価を行った。表3に乳化組成物中の各成分の割合(質量%)とともに評価結果とを示す。
<Example 24>
(1) To 16 g of glycerin (manufactured by Wako Pure Chemical Industries, Ltd.), 2 g of an aqueous dispersion of nanofibers derived from crystalline cellulose and 32 g of ion-exchanged water were added, and the mixture was stirred for 10 minutes to prepare a uniform mixture. did.
(2) 50 g of silicone oil was added to the mixture prepared in (1) at a rate of 5 ml / min with a three-one motor stirrer.
(3) After completion of the addition, the mixture was stirred at 300 rpm for 15 minutes to obtain a D-phase medium oil type (O / D type) emulsified composition. The dispersion stability of the prepared emulsified composition was evaluated. Table 3 shows the evaluation results together with the ratio (mass%) of each component in the emulsified composition.
<実施例25>
油溶性物質として、実施例18と同じ流動パラフィン80gを使用して、以下の手順で乳化組成物(D相中油型(O/D型)乳化組成物)の作製を行った。
(1)16gのグリセリンに実施例17で使用した結晶性セルロース由来のナノファイバー水分散体を3g、イオン交換水を1gそれぞれ添加して、撹拌を10分間行い、均一な混合体を作製した。
(2)スリーワンモーター撹拌機で流動パラフィンを(1)で作製した混合体に5ml/分の速度で添加した。
(3)添加終了後、300rpmで15分間撹拌し、D相中油型(O/D型)乳化組成物からなる自己乳化性油脂を得た。作製した乳化組成物について分散安定性の評価を行った。表3に乳化組成物中の各成分の割合(質量%)とともに評価結果とを示す。
<Example 25>
Using 80 g of the same liquid paraffin as in Example 18 as the oil-soluble substance, an emulsified composition (D phase medium oil type (O / D type) emulsified composition) was prepared by the following procedure.
(1) To 16 g of glycerin, 3 g of the crystalline cellulose-derived nanofiber aqueous dispersion used in Example 17 and 1 g of ion-exchanged water were added, and stirring was performed for 10 minutes to prepare a uniform mixture.
(2) Liquid paraffin was added to the mixture prepared in (1) at a rate of 5 ml / min with a three-one motor stirrer.
(3) After completion of the addition, the mixture was stirred at 300 rpm for 15 minutes to obtain a self-emulsifying fat and oil composed of a D-phase medium oil type (O / D type) emulsifying composition. The dispersion stability of the prepared emulsified composition was evaluated. Table 3 shows the evaluation results together with the ratio (mass%) of each component in the emulsified composition.
<実施例26>
油溶性物質として、流動パラフィン80gをスクワラン80gとした以外は実施例25と同様にして、D相中油型(O/D型)乳化組成物を作製し分散安定性の評価を行った。結果を表3に示す。
<Example 26>
A D-phase medium oil type (O / D type) emulsified composition was prepared in the same manner as in Example 25 except that 80 g of liquid paraffin was used as the oil-soluble substance and 80 g of squalane was used, and the dispersion stability was evaluated. The results are shown in Table 3.
<実施例27>
油溶性物質として、流動パラフィン80gをオリーブ油80gとした以外は実施例25と同様にして、D相中油型(O/D型)乳化組成物を作製し分散安定性の評価を行った。結果を表3に示す。
<Example 27>
A D-phase medium oil type (O / D type) emulsified composition was prepared and the dispersion stability was evaluated in the same manner as in Example 25 except that 80 g of liquid paraffin was used as an oil-soluble substance and 80 g of olive oil. The results are shown in Table 3.
<実施例28>
油溶性物質として、流動パラフィン80gをホホバ油80gとした以外は実施例25と同様にして、D相中油型(O/D型)乳化組成物を作製し分散安定性の評価を行った。結果を表3に示す。
<Example 28>
A D-phase medium oil type (O / D type) emulsified composition was prepared in the same manner as in Example 25 except that 80 g of liquid paraffin was used as the oil-soluble substance and 80 g of jojoba oil was used, and the dispersion stability was evaluated. The results are shown in Table 3.
図4は、実施例17〜21である、結晶性セルロース由来のナノファイバーとシリコーンオイル、流動パラフィン、スクワラン、オリーブ油、ホホバ油のそれぞれとを撹拌して得られた乳化組成物を観察した画像であり、72時間後の乳化組成物の画像である。
図5は、実施例22、25〜28である、結晶性セルロース由来のナノファイバーとシリコーンオイル、流動パラフィン、スクワラン、オリーブ油、ホホバ油のそれぞれとを撹拌して得られた乳化組成物を観察した画像であり、72時間後の乳化組成物の画像である。
FIG. 4 is an image of observing the emulsified composition obtained by stirring the nanofibers derived from crystalline cellulose and each of silicone oil, liquid paraffin, squalane, olive oil, and jojoba oil, which are Examples 17 to 21. Yes, it is an image of the emulsified composition after 72 hours.
FIG. 5 observed the emulsified composition obtained by stirring the nanofibers derived from crystalline cellulose and each of silicone oil, liquid paraffin, squalane, olive oil, and jojoba oil, which are Examples 22 and 25 to 28. It is an image, and is an image of an emulsified composition after 72 hours.
<実施例29>
油溶性物質としてシリコーンオイル80g使用して、以下の手順で乳化組成物(D相中油型(O/D型)乳化組成物)の作製を行った。
<Example 29>
Using 80 g of silicone oil as an oil-soluble substance, an emulsified composition (D phase medium oil type (O / D type) emulsified composition) was prepared by the following procedure.
(1)16gのグリセリン(富士フイルム和光純薬(株)製、以下の例も同様)に、粉末セルロース由来のナノファイバー水分散体((株)スギノマシン製BiNFi−s(WFO−10010)、粉末セルロース由来のナノファイバー濃度10wt%、平均径20〜50nm、以下の粉末セルロース由来のナノファイバーの例も同様)とイオン交換水をそれぞれ2g添加して、撹拌を10分間行い、均一な混合体を作製した。
(2)スリーワンモーター撹拌機でシリコーンオイルを(1)で作製した混合体に5ml/分の速度で添加した。
(3)添加終了後、300rpmで15分間攪拌し、D相中油型(O/D型)乳化組成物を得た。作製した乳化組成物について分散安定性の評価を行った。表4に乳化組成物中の各成分の割合(質量%)とともに評価結果とを示す。
(1) 16 g of glycerin (manufactured by Fujifilm Wako Pure Chemical Industries, Ltd., the same applies to the following examples), nanofiber aqueous dispersion derived from powdered cellulose (BiNFi-s (WFO-10010) manufactured by Sugino Machine Co., Ltd.), Add 2 g each of nanofibers derived from powdered cellulose (nanofiber concentration 10 wt%, average diameter 20-50 nm, the same applies to the following examples of nanofibers derived from powdered cellulose) and ion-exchanged water, and stir for 10 minutes to obtain a uniform mixture. Was produced.
(2) Silicone oil was added to the mixture prepared in (1) at a rate of 5 ml / min with a three-one motor stirrer.
(3) After completion of the addition, the mixture was stirred at 300 rpm for 15 minutes to obtain a D-phase medium oil type (O / D type) emulsified composition. The dispersion stability of the prepared emulsified composition was evaluated. Table 4 shows the evaluation results together with the ratio (mass%) of each component in the emulsified composition.
<実施例30>
油溶性物質として、シリコーンオイル80gを流動パラフィン80gとした以外は実施例29と同様にして、D相中油型(O/D型)乳化組成物を作製し分散安定性の評価を行った。結果を表4に示す。
<Example 30>
A D-phase medium oil type (O / D type) emulsified composition was prepared in the same manner as in Example 29 except that 80 g of silicone oil was used as the oil-soluble substance and 80 g of liquid paraffin was used, and the dispersion stability was evaluated. The results are shown in Table 4.
<実施例31>
油溶性物質として、シリコーンオイル80gをスクワラン80gとした以外は実施例29と同様にして、D相中油型(O/D型)乳化組成物を作製し分散安定性の評価を行った。結果を表4に示す。
<Example 31>
A D-phase medium oil type (O / D type) emulsified composition was prepared and the dispersion stability was evaluated in the same manner as in Example 29 except that 80 g of silicone oil was used as the oil-soluble substance and 80 g of squalane was used. The results are shown in Table 4.
<実施例32>
油溶性物質として、シリコーンオイル80gをオリーブ油80gとした以外は実施例29と同様にして、D相中油型(O/D型)乳化組成物を作製し分散安定性の評価を行った。結果を表4に示す。
<Example 32>
A D-phase medium oil type (O / D type) emulsified composition was prepared and the dispersion stability was evaluated in the same manner as in Example 29 except that 80 g of silicone oil was used as the oil-soluble substance and 80 g of olive oil. The results are shown in Table 4.
<実施例33>
油溶性物質として、シリコーンオイル80gをホホバ油80gとした以外は実施例29と同様にして、D相中油型(O/D型)乳化組成物を作製し分散安定性の評価を行った。結果を表4に示す。
<Example 33>
A D-phase medium oil type (O / D type) emulsified composition was prepared in the same manner as in Example 29 except that 80 g of silicone oil was used as the oil-soluble substance and 80 g of jojoba oil was used, and the dispersion stability was evaluated. The results are shown in Table 4.
<比較例16>
比較例16として、油溶性物質としてシリコーンオイル80gを使用して、以下の手順で乳化組成物(D相中油型(O/D型)乳化組成物)の作製を行った。
(1)16gのグリセリン(富士フイルム和光純薬製)に粉末セルロース粒子(平均粒径10〜250μm、アスペクト比(長径/短径)10未満)を0.2gとイオン交換水を3.8g添加して、撹拌を10分間行い、均一な混合体を作製した。
(2)スリーワンモーター撹拌機でシリコーンオイルを(1)で作製した混合体に5ml/分の速度で添加した。
(3)添加終了後、300rpmで15分間攪拌し、D相中油型(O/D型)乳化組成物からなる自己乳化性油脂を得た。作製した乳化組成物について分散安定性の評価を行った。表4に乳化組成物中の各成分の割合(質量%)とともに評価結果とを示す。
<Comparative Example 16>
As Comparative Example 16, using 80 g of silicone oil as an oil-soluble substance, an emulsified composition (D phase medium oil type (O / D type) emulsified composition) was prepared by the following procedure.
(1) Add 0.2 g of powdered cellulose particles (average particle size 10 to 250 μm, aspect ratio (major axis / minor axis) less than 10) and 3.8 g of ion-exchanged water to 16 g of glycerin (manufactured by Fujifilm Wako Pure Chemical Industries, Ltd.). Then, stirring was carried out for 10 minutes to prepare a uniform mixture.
(2) Silicone oil was added to the mixture prepared in (1) at a rate of 5 ml / min with a three-one motor stirrer.
(3) After completion of the addition, the mixture was stirred at 300 rpm for 15 minutes to obtain a self-emulsifying fat and oil composed of a D-phase medium oil type (O / D type) emulsifying composition. The dispersion stability of the prepared emulsified composition was evaluated. Table 4 shows the evaluation results together with the ratio (mass%) of each component in the emulsified composition.
<比較例17>
油溶性物質として、シリコーンオイル80gを流動パラフィン80gとした以外は比較例16と同様にして、D相中油型(O/D型)乳化組成物を作製し分散安定性の評価を行った。結果を表4に示す。
<Comparative example 17>
A D-phase medium oil type (O / D type) emulsified composition was prepared and the dispersion stability was evaluated in the same manner as in Comparative Example 16 except that 80 g of silicone oil was used as the oil-soluble substance and 80 g of liquid paraffin was used. The results are shown in Table 4.
<比較例18>
油溶性物質として、シリコーンオイル80gをスクワラン80gとした以外は比較例16と同様にして、D相中油型(O/D型)乳化組成物を作製し分散安定性の評価を行った。結果を表4に示す。
<Comparative Example 18>
A D-phase medium oil type (O / D type) emulsified composition was prepared and the dispersion stability was evaluated in the same manner as in Comparative Example 16 except that 80 g of silicone oil was used as the oil-soluble substance and 80 g of squalane was used. The results are shown in Table 4.
<比較例19>
油溶性物質として、シリコーンオイル80gをオリーブ油80gとした以外は比較例16と同様にして、D相中油型(O/D型)乳化組成物を作製し分散安定性の評価を行った。結果を表4に示す。
<Comparative Example 19>
A D-phase medium oil type (O / D type) emulsified composition was prepared and the dispersion stability was evaluated in the same manner as in Comparative Example 16 except that 80 g of silicone oil was used as the oil-soluble substance and 80 g of olive oil. The results are shown in Table 4.
<比較例20>
油溶性物質として、シリコーンオイル80gをホホバ油80gとした以外は比較例16と同様にして、D相中油型(O/D型)乳化組成物を作製し分散安定性の評価を行った。結果を表4に示す。
<Comparative Example 20>
A D-phase medium oil type (O / D type) emulsified composition was prepared and the dispersion stability was evaluated in the same manner as in Comparative Example 16 except that 80 g of silicone oil was used as the oil-soluble substance and 80 g of jojoba oil was used. The results are shown in Table 4.
<実施例34>
油溶性物質として、実施例29と同じシリコーンオイル80gを使用して、以下の手順で乳化組成物(D相中油型(O/D型)乳化組成物)の作製を行った。
(1)16gのグリセリンに実施例29で使用した粉末セルロース由来のナノファイバー水分散体を4g添加して、撹拌を10分間行い、均一な混合体を作製した。
(2)スリーワンモーター撹拌機でシリコーンオイルを(1)で作製した混合体に5ml/分の速度で添加した。
(3)添加終了後、300rpmで15分間撹拌し、D相中油型(O/D型)乳化組成物からなる自己乳化性油脂を得た。作製した乳化組成物について分散安定性の評価を行った。表4に乳化組成物中の各成分の割合(質量%)とともに評価結果とを示す。
<Example 34>
Using 80 g of the same silicone oil as in Example 29 as the oil-soluble substance, an emulsified composition (D phase medium oil type (O / D type) emulsified composition) was prepared by the following procedure.
(1) 4 g of the nanofiber aqueous dispersion derived from powdered cellulose used in Example 29 was added to 16 g of glycerin, and the mixture was stirred for 10 minutes to prepare a uniform mixture.
(2) Silicone oil was added to the mixture prepared in (1) at a rate of 5 ml / min with a three-one motor stirrer.
(3) After completion of the addition, the mixture was stirred at 300 rpm for 15 minutes to obtain a self-emulsifying fat and oil composed of a D-phase medium oil type (O / D type) emulsifying composition. The dispersion stability of the prepared emulsified composition was evaluated. Table 4 shows the evaluation results together with the ratio (mass%) of each component in the emulsified composition.
<実施例35>
油溶性物質として、シリコーンオイル80gを流動パラフィン80gとした以外は実施例34と同様にして、D相中油型(O/D型)乳化組成物を作製し分散安定性の評価を行った。結果を表4に示す。
<Example 35>
A D-phase medium oil type (O / D type) emulsified composition was prepared and the dispersion stability was evaluated in the same manner as in Example 34 except that 80 g of silicone oil was used as the oil-soluble substance and 80 g of liquid paraffin was used. The results are shown in Table 4.
<実施例36>
油溶性物質として、シリコーンオイル80gをスクワラン80gとした以外は実施例34と同様にして、D相中油型(O/D型)乳化組成物を作製し分散安定性の評価を行った。結果を表4に示す。
<Example 36>
A D-phase medium oil type (O / D type) emulsified composition was prepared and the dispersion stability was evaluated in the same manner as in Example 34 except that 80 g of silicone oil was used as the oil-soluble substance and 80 g of squalane was used. The results are shown in Table 4.
<実施例37>
油溶性物質として、シリコーンオイル80gをオリーブ油80gとした以外は実施例34と同様にして、D相中油型(O/D型)乳化組成物を作製し分散安定性の評価を行った。結果を表4に示す。
<Example 37>
A D-phase medium oil type (O / D type) emulsified composition was prepared and the dispersion stability was evaluated in the same manner as in Example 34 except that 80 g of silicone oil was used as the oil-soluble substance and 80 g of olive oil. The results are shown in Table 4.
<実施例38>
油溶性物質として、シリコーンオイル80gをホホバ油80gとした以外は実施例34と同様にして、D相中油型(O/D型)乳化組成物を作製し分散安定性の評価を行った。結果を表4に示す。
<Example 38>
A D-phase medium oil type (O / D type) emulsified composition was prepared and the dispersion stability was evaluated in the same manner as in Example 34 except that 80 g of silicone oil was used as the oil-soluble substance and 80 g of jojoba oil was used. The results are shown in Table 4.
図6は、実施例29〜33である、粉末セルロース由来のナノファイバーとシリコーンオイル、流動パラフィン、スクワラン、オリーブ油、ホホバ油のそれぞれとを撹拌して得られた乳化組成物を観察した画像であり、72時間後の乳化組成物の画像である。
図7は、実施例34〜38である、粉末セルロース由来のナノファイバーとシリコーンオイル、流動パラフィン、スクワラン、オリーブ油、ホホバ油のそれぞれとを撹拌して得られた乳化組成物を観察した画像であり、72時間後の乳化組成物の画像である。
FIG. 6 is an image of observing the emulsified composition obtained by stirring nanofibers derived from powdered cellulose and each of silicone oil, liquid paraffin, squalane, olive oil, and jojoba oil, which are Examples 29 to 33. , 72 hours later, is an image of the emulsified composition.
FIG. 7 is an image of observing the emulsified composition obtained by stirring nanofibers derived from powdered cellulose and each of silicone oil, liquid paraffin, squalane, olive oil, and jojoba oil, which are Examples 34 to 38. , 72 hours later, is an image of the emulsified composition.
以上の実施例等から、本発明の乳化組成物は、加熱処理が必要なレトルト食品や医療薬品や化粧料への適用が容易となり、また、例えば、化粧料に適用した場合に、熱処理に影響を受ける原料を処方に組み入れることが可能となり、その温度管理範囲の幅が広くなり、温度管理が容易となる等の効果が得られる。 From the above examples and the like, the emulsified composition of the present invention can be easily applied to retort foods, medical chemicals and cosmetics that require heat treatment, and, for example, when applied to cosmetics, it affects heat treatment. It is possible to incorporate the raw material to be received into the formulation, widen the range of the temperature control range, and obtain the effect of facilitating the temperature control.
Claims (5)
A cosmetic composition comprising the emulsified composition according to any one of claims 1 to 3 or the oil-in-water (O / W type) emulsified composition according to claim 4.
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