JP6895968B2 - サイトカインおよびカルボキシルエステラーゼを発現する腫瘍溶解性改変ワクシニアウイルス、および、その使用方法 - Google Patents

サイトカインおよびカルボキシルエステラーゼを発現する腫瘍溶解性改変ワクシニアウイルス、および、その使用方法 Download PDF

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JP6895968B2
JP6895968B2 JP2018531280A JP2018531280A JP6895968B2 JP 6895968 B2 JP6895968 B2 JP 6895968B2 JP 2018531280 A JP2018531280 A JP 2018531280A JP 2018531280 A JP2018531280 A JP 2018531280A JP 6895968 B2 JP6895968 B2 JP 6895968B2
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cancer
promoter
vaccinia virus
virus
cells
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JP2018526450A (ja
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ホ ファン，テ
ホ ファン，テ
ヒ イ，ナム
ヒ イ，ナム
チョ，ウンア
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シルラジェン インコーポレイテッド
シルラジェン インコーポレイテッド
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JP2018531280A 2015-09-08 2016-09-02 サイトカインおよびカルボキシルエステラーゼを発現する腫瘍溶解性改変ワクシニアウイルス、および、その使用方法 Expired - Fee Related JP6895968B2 (ja)

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US201562215651P 2015-09-08 2015-09-08
US62/215,651 2015-09-08
PCT/KR2016/009866 WO2017043815A1 (en) 2015-09-08 2016-09-02 Modified oncolytic vaccinia viruses expressing a cytokine and a car- boxylesterase and methods of use thereof

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JP2018526450A JP2018526450A (ja) 2018-09-13
JP2018526450A5 JP2018526450A5 (https=) 2019-08-29
JP6895968B2 true JP6895968B2 (ja) 2021-06-30

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US (1) US10646524B2 (https=)
EP (1) EP3347460A4 (https=)
JP (1) JP6895968B2 (https=)
KR (1) KR102674362B1 (https=)
CN (1) CN108350434B (https=)
AU (1) AU2016320355B2 (https=)
CA (1) CA2996120C (https=)
HK (1) HK1255192A1 (https=)
WO (1) WO2017043815A1 (https=)

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CN108025056B (zh) * 2015-06-19 2022-01-14 新罗杰股份有限公司 用于病毒栓塞的组合物和方法
JP7025339B2 (ja) 2016-02-25 2022-02-24 メモリアル スローン ケタリング キャンサー センター 癌免疫療法のための、チミジンキナーゼの欠失を伴い、ヒトｆｌｔ３ｌまたはｇｍ－ｃｓｆの発現を伴うかまたは伴わない、複製可能な弱毒化ワクシニアウイルス
CN109152827B (zh) 2016-02-25 2023-07-21 纪念斯隆凯特琳癌症中心 重组mva或表达人flt3l的mvaδe3l及其作为抗固体肿瘤的免疫治疗剂的用途
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CN109735558B (zh) * 2018-12-12 2022-04-15 中南大学 一种重组car19-il24基因、慢病毒载体、car19-il24-t细胞及应用
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WO2022036159A2 (en) 2020-08-12 2022-02-17 Actym Therapeutics, Inc. Immunostimulatory bacteria-based vaccines, therapeutics, and rna delivery platforms
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AU2016320355B2 (en) 2020-10-08
EP3347460A1 (en) 2018-07-18
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