JP6879496B2 - 小分子のためのサンドイッチアッセイ - Google Patents

小分子のためのサンドイッチアッセイ Download PDF

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Publication number
JP6879496B2
JP6879496B2 JP2018521922A JP2018521922A JP6879496B2 JP 6879496 B2 JP6879496 B2 JP 6879496B2 JP 2018521922 A JP2018521922 A JP 2018521922A JP 2018521922 A JP2018521922 A JP 2018521922A JP 6879496 B2 JP6879496 B2 JP 6879496B2
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Japan
Prior art keywords
sirolimus
antibody
binding
tacrolimus
binding partner
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JP2018521922A
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English (en)
Japanese (ja)
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JP2018534568A5 (enExample
JP2018534568A (ja
Inventor
ウエイ、ティエ
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Siemens Healthcare Diagnostics Inc
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Siemens Healthcare Diagnostics Inc
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/9493—Immunosupressants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2470/00—Immunochemical assays or immunoassays characterised by the reaction format or reaction type
    • G01N2470/04—Sandwich assay format

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2018521922A 2015-10-29 2016-10-12 小分子のためのサンドイッチアッセイ Active JP6879496B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562247970P 2015-10-29 2015-10-29
US62/247,970 2015-10-29
PCT/US2016/056551 WO2017074703A1 (en) 2015-10-29 2016-10-12 Sandwich assay for small molecules

Publications (3)

Publication Number Publication Date
JP2018534568A JP2018534568A (ja) 2018-11-22
JP2018534568A5 JP2018534568A5 (enExample) 2019-10-24
JP6879496B2 true JP6879496B2 (ja) 2021-06-02

Family

ID=58630580

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2018521922A Active JP6879496B2 (ja) 2015-10-29 2016-10-12 小分子のためのサンドイッチアッセイ

Country Status (5)

Country Link
US (3) US20180306828A1 (enExample)
EP (1) EP3368900B1 (enExample)
JP (1) JP6879496B2 (enExample)
ES (1) ES2863624T3 (enExample)
WO (1) WO2017074703A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016100116A1 (en) * 2014-12-17 2016-06-23 Siemens Healthcare Diagnostics Inc. Sandwich assay design for small molecules
US10408764B2 (en) 2017-09-13 2019-09-10 Applied Materials Israel Ltd. System, method and computer program product for object examination
CN114008457A (zh) * 2019-06-28 2022-02-01 美国西门子医学诊断股份有限公司 使用颗粒增强凝集检测的夹心免疫测定试剂及其生产和使用方法
CN110907649A (zh) * 2019-12-23 2020-03-24 山东莱博生物科技有限公司 一种检测短链脂肪酸的试剂盒及其应用
CN113176403A (zh) * 2021-04-21 2021-07-27 佛山职业技术学院 一种检测啶虫脒的双抗夹心elisa试剂盒及其应用
CN115267208B (zh) * 2022-09-27 2023-01-03 上海芯超生物科技有限公司 一种幽门螺旋杆菌抗体检测用抗原、试剂盒及其制备方法
CN117871874A (zh) * 2023-12-07 2024-04-12 深圳市新产业生物医学工程股份有限公司 小分子物质免疫检测方法

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3817837A (en) 1971-05-14 1974-06-18 Syva Corp Enzyme amplification assay
US4275149A (en) 1978-11-24 1981-06-23 Syva Company Macromolecular environment control in specific receptor assays
US4318980A (en) 1978-04-10 1982-03-09 Miles Laboratories, Inc. Heterogenous specific binding assay employing a cycling reactant as label
ATE98700T1 (de) 1987-06-05 1994-01-15 Fujisawa Pharmaceutical Co Anti-fr-900506-stoffe-antikoerper und hoechstempfindliches enzym-immunoassay-verfahren.
US5089390A (en) 1987-09-04 1992-02-18 Syntex (U.S.A.) Inc. 2-methyl-4-hexene- and 2-methyl-4-heptene-1,2-diol derivatives
US5185243A (en) 1988-08-25 1993-02-09 Syntex (U.S.A.) Inc. Method for detection of specific nucleic acid sequences
US5164495A (en) 1991-09-18 1992-11-17 Abbott Laboratories Method for preparing a dicarboxylic acid half-acid ester of FK506
US6187547B1 (en) 1993-09-08 2001-02-13 Novartis Ag Assay kit
CA2286311A1 (en) * 1997-04-09 1998-10-15 Isotechnika, Inc. Method for production of antibodies to specific sites of rapamycin
US6709873B1 (en) * 1997-04-09 2004-03-23 Isodiagnostika Inc. Method for production of antibodies to specific sites of rapamycin
AU763822B2 (en) * 1998-10-09 2003-07-31 Isotechnika, Inc. Methods for the production of antibodies to specific regions of cyclosporine and cyclosporine metabolites
US7186518B2 (en) 2003-11-21 2007-03-06 Dade Behring Inc. Method and composition useful for determining FK 506
US8021849B2 (en) * 2004-11-05 2011-09-20 Siemens Healthcare Diagnostics Inc. Methods and kits for the determination of sirolimus in a sample
CA2602732A1 (en) * 2005-04-06 2006-10-12 Abbott Laboratories Methods to measure immunosuppressive tacrolimus, sirolimus, and cyclosporin a complexes in a blood sample
US7189582B2 (en) * 2005-04-27 2007-03-13 Dade Behring Inc. Compositions and methods for detection of sirolimus
ES2393135T3 (es) * 2006-12-29 2012-12-18 Abbott Laboratories Ensayo mejorado para fármacos inmunosupresores
US7617986B2 (en) * 2007-01-10 2009-11-17 Datacard Corporation Laminate security feature
US8586322B2 (en) * 2012-03-07 2013-11-19 Siemens Healthcare Diagnostics, Inc Sandwich assay for immunosuppressant drugs
US9244083B2 (en) * 2012-11-30 2016-01-26 Siemens Healthcare Diagnostics Inc. Compositions and methods for detecting vitamin D
US9121859B2 (en) 2012-12-04 2015-09-01 Siemens Healthcare Diagnostics Inc. Compounds and methods for determination of FKBP-binding immunosuppressant drugs
US20140308751A1 (en) * 2013-04-12 2014-10-16 Siemens Healthcare Diagnostics Inc. Assays for Analyte Homologs
WO2016100116A1 (en) * 2014-12-17 2016-06-23 Siemens Healthcare Diagnostics Inc. Sandwich assay design for small molecules
ES2992864T3 (en) * 2018-11-02 2024-12-18 Siemens Healthcare Diagnostics Inc Binding competitors for use in macrophilin-binding pharmaceutical assays and methods of use thereof
CN114008457A (zh) * 2019-06-28 2022-02-01 美国西门子医学诊断股份有限公司 使用颗粒增强凝集检测的夹心免疫测定试剂及其生产和使用方法

Also Published As

Publication number Publication date
US20240159781A1 (en) 2024-05-16
ES2863624T3 (es) 2021-10-11
US20210199677A1 (en) 2021-07-01
EP3368900A1 (en) 2018-09-05
US11913965B2 (en) 2024-02-27
US20180306828A1 (en) 2018-10-25
WO2017074703A1 (en) 2017-05-04
EP3368900B1 (en) 2020-12-23
EP3368900A4 (en) 2018-09-05
JP2018534568A (ja) 2018-11-22

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