JP6868014B2 - 翼状片を治療するための組成物及び方法 - Google Patents

翼状片を治療するための組成物及び方法 Download PDF

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JP6868014B2
JP6868014B2 JP2018515193A JP2018515193A JP6868014B2 JP 6868014 B2 JP6868014 B2 JP 6868014B2 JP 2018515193 A JP2018515193 A JP 2018515193A JP 2018515193 A JP2018515193 A JP 2018515193A JP 6868014 B2 JP6868014 B2 JP 6868014B2
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pterygium
nintedanib
eye
pharmaceutical composition
composition according
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JP2018521120A (ja
JP2018521120A5 (enExample
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ニー，ジンソン
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クラウドブレイク・セラピューティクス・エル・エル・シー
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Priority to JP2023024878A priority patent/JP7571171B2/ja
Priority to JP2024035547A priority patent/JP7838007B2/ja
Priority to JP2025044397A priority patent/JP7774170B2/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
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    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
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    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
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    • A61K9/0012—Galenical forms characterised by the site of application
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    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts or implants
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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  • Health & Medical Sciences (AREA)
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  • Life Sciences & Earth Sciences (AREA)
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  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
JP2018515193A 2015-06-06 2016-06-03 翼状片を治療するための組成物及び方法 Active JP6868014B2 (ja)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2021066291A JP7234283B2 (ja) 2015-06-06 2021-04-09 翼状片を治療するための組成物及び方法
JP2023024878A JP7571171B2 (ja) 2015-06-06 2023-02-21 翼状片を治療するための組成物及び方法
JP2024035547A JP7838007B2 (ja) 2015-06-06 2024-03-08 翼状片を治療するための組成物及び方法
JP2025044397A JP7774170B2 (ja) 2015-06-06 2025-03-19 翼状片を治療するための組成物及び方法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562172063P 2015-06-06 2015-06-06
US62/172,063 2015-06-06
US201562186660P 2015-06-30 2015-06-30
US62/186,660 2015-06-30
PCT/US2016/035726 WO2016200688A1 (en) 2015-06-06 2016-06-03 Compositions and methods for treating pterygium

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JP2021066291A Division JP7234283B2 (ja) 2015-06-06 2021-04-09 翼状片を治療するための組成物及び方法

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JP2018521120A JP2018521120A (ja) 2018-08-02
JP2018521120A5 JP2018521120A5 (enExample) 2019-07-04
JP6868014B2 true JP6868014B2 (ja) 2021-05-12

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JP2018515193A Active JP6868014B2 (ja) 2015-06-06 2016-06-03 翼状片を治療するための組成物及び方法
JP2021066291A Active JP7234283B2 (ja) 2015-06-06 2021-04-09 翼状片を治療するための組成物及び方法
JP2023024878A Active JP7571171B2 (ja) 2015-06-06 2023-02-21 翼状片を治療するための組成物及び方法
JP2024035547A Active JP7838007B2 (ja) 2015-06-06 2024-03-08 翼状片を治療するための組成物及び方法
JP2025044397A Active JP7774170B2 (ja) 2015-06-06 2025-03-19 翼状片を治療するための組成物及び方法

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JP2021066291A Active JP7234283B2 (ja) 2015-06-06 2021-04-09 翼状片を治療するための組成物及び方法
JP2023024878A Active JP7571171B2 (ja) 2015-06-06 2023-02-21 翼状片を治療するための組成物及び方法
JP2024035547A Active JP7838007B2 (ja) 2015-06-06 2024-03-08 翼状片を治療するための組成物及び方法
JP2025044397A Active JP7774170B2 (ja) 2015-06-06 2025-03-19 翼状片を治療するための組成物及び方法

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US (7) US9980901B2 (enExample)
EP (2) EP3302379B1 (enExample)
JP (5) JP6868014B2 (enExample)
KR (5) KR20260025887A (enExample)
CN (2) CN114010787A (enExample)
AU (3) AU2016276170B2 (enExample)
ES (1) ES2971096T3 (enExample)
MX (2) MX393691B (enExample)
TW (1) TWI714596B (enExample)
WO (1) WO2016200688A1 (enExample)

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