JP6866379B2 - 神経発達障害療法 - Google Patents

神経発達障害療法 Download PDF

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JP6866379B2
JP6866379B2 JP2018536130A JP2018536130A JP6866379B2 JP 6866379 B2 JP6866379 B2 JP 6866379B2 JP 2018536130 A JP2018536130 A JP 2018536130A JP 2018536130 A JP2018536130 A JP 2018536130A JP 6866379 B2 JP6866379 B2 JP 6866379B2
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mice
day
syndrome
rett syndrome
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JP2019502716A5 (enExample
JP2019502716A (ja
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クリストファー ユー． ミスリング，
クリストファー ユー． ミスリング，
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アナベックス ライフ サイエンシズ コーポレイション
アナベックス ライフ サイエンシズ コーポレイション
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2018536130A 2016-01-26 2017-01-24 神経発達障害療法 Active JP6866379B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662287062P 2016-01-26 2016-01-26
US62/287,062 2016-01-26
PCT/US2017/014702 WO2017132127A1 (en) 2016-01-26 2017-01-24 Neurodevelopmental disorder therapy

Related Child Applications (1)

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JP2021010835A Division JP7153950B2 (ja) 2016-01-26 2021-01-27 神経発達障害療法

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JP2019502716A JP2019502716A (ja) 2019-01-31
JP2019502716A5 JP2019502716A5 (enExample) 2020-03-05
JP6866379B2 true JP6866379B2 (ja) 2021-04-28

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JP2018536130A Active JP6866379B2 (ja) 2016-01-26 2017-01-24 神経発達障害療法
JP2021010835A Active JP7153950B2 (ja) 2016-01-26 2021-01-27 神経発達障害療法
JP2022153402A Pending JP2022173373A (ja) 2016-01-26 2022-09-27 神経発達障害療法

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JP2022153402A Pending JP2022173373A (ja) 2016-01-26 2022-09-27 神経発達障害療法

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US (5) US10507196B2 (enExample)
EP (2) EP4104831A1 (enExample)
JP (3) JP6866379B2 (enExample)
CA (1) CA3012199C (enExample)
WO (1) WO2017132127A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6866379B2 (ja) 2016-01-26 2021-04-28 アナベックス ライフ サイエンシズ コーポレイション 神経発達障害療法
WO2018022848A1 (en) 2016-07-27 2018-02-01 Anavex Life Sciences Corp. A2-73 as a therapeutic for insomnia, anxiety, and agitation
CN112105349A (zh) 2018-04-12 2020-12-18 阿纳韦克斯生命科学公司 A2-73结晶多晶型物质组合物及其使用方法
US12383526B2 (en) 2018-05-18 2025-08-12 Anavex Life Sciences Corp. Optimized sigma-1 agonist method of responder selection and treatment
CN114390937A (zh) * 2019-06-26 2022-04-22 加利福尼亚大学董事会 用于治疗史密斯-马吉利综合征的方法和组合物
US12642784B2 (en) 2019-07-22 2026-06-02 Anavex Life Sciences Corp. ANAVEX2-73 for the treatment of genetic neurodevelopmental disorders
WO2025101987A1 (en) 2023-11-08 2025-05-15 CaddyHack, Inc. Dynamic data collection and systematic processing system
WO2025231180A1 (en) * 2024-05-01 2025-11-06 Anavex Life Sciences Corp. Blarcamesine correction of eeg biomarkers in fragile x syndrome

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR1002616B (el) 1996-02-21 1997-02-20 Συνθεση και μεθοδος συνθεσης μοριου: τετραυδρο-ν,ν-διμεθυλο-2,2-διφαινυλο-3-φουρανομεθαναμινης (αε 37), αντισπασμωδικης, αντικαταθλιπτικης και νοοτροπικης δρασης.
GR1004208B (en) * 2001-10-15 2003-04-04 Αλεξανδρος Βαμβακιδης Aminotetrahydrofuran derivatives, muscarinic/sigma/sodium channel ligands, with synergic sigma/muscarinic (neuroactivating) and sigma/sodium channel (neuroprotective) components, as prototypical activating - neuroprotectors and neuroregenerative drugs
FR2897535B1 (fr) 2006-02-21 2012-07-20 Alexandre Vamvakides Les sigma ligands : (mono- ou di-alkylaminoalkyl)-y- butyrolactones, leurs analogues aminotetrodrafuranes et les (1-adamantyl) benzene(s) alkylamines en tant que modulateurs prototypiques des recepteurs cellulaires
GR1005865B (el) * 2007-01-17 2008-04-07 Anavex Life Sciences Corp. Νεοι συνδετες των σιγμα υποδοχεων με αντι-αποπτωτικες και/η προ-αποπτωτικες ιδιοτητες επι των κυτταρικων βιοχημικων μηχανισμων, με νευρο-προστατευτικη, αντικαρκινικη, αντι-μεταστατικη και αντι- αντι-(χρονιο)φλεγμονικη δραση.
BRPI0812768A2 (pt) 2007-06-08 2014-12-02 Massachusetts Inst Technology Igf para o tratamento de síndrome de rett e transtornos sinápticos.
GR1006794B (el) 2009-02-26 2010-06-04 Αλεξανδρος Βαμβακιδης Προσδετες των σιγμα υποδοχεων, αντι-αποπτωτικες και προ-αποπτωτικες ιδιοτητες επι των κυτταρικων μηχανισμων, και με πρωτοτυπη κυτταρο-προστατευτικη αλλα και αντικαρκινικη δραση
NZ609640A (en) 2010-10-25 2015-06-26 Univ D’Aix Marseille Treatment of mecp2-associated disorders
CN104583402A (zh) 2012-05-16 2015-04-29 Rana医疗有限公司 用于调节mecp2表达的组合物和方法
US10555916B2 (en) * 2013-01-25 2020-02-11 Case Western Reserve University NMDAR antagonist for the treatment of pervasive development disorders
JP6866379B2 (ja) * 2016-01-26 2021-04-28 アナベックス ライフ サイエンシズ コーポレイション 神経発達障害療法
US12383526B2 (en) * 2018-05-18 2025-08-12 Anavex Life Sciences Corp. Optimized sigma-1 agonist method of responder selection and treatment

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Publication number Publication date
US20200246303A1 (en) 2020-08-06
US10888543B2 (en) 2021-01-12
US20210228532A1 (en) 2021-07-29
JP7153950B2 (ja) 2022-10-17
CA3012199C (en) 2024-05-07
JP2022173373A (ja) 2022-11-18
EP3407880B1 (en) 2022-08-17
JP2019502716A (ja) 2019-01-31
JP2021063136A (ja) 2021-04-22
US11839600B2 (en) 2023-12-12
US20240066003A1 (en) 2024-02-29
US11446275B2 (en) 2022-09-20
WO2017132127A1 (en) 2017-08-03
US10507196B2 (en) 2019-12-17
CA3012199A1 (en) 2017-08-03
US20220387373A1 (en) 2022-12-08
US20190022052A1 (en) 2019-01-24
EP4104831A1 (en) 2022-12-21
EP3407880A1 (en) 2018-12-05

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