JP6833703B2 - 卒中サブタイプの判定装置および方法 - Google Patents

卒中サブタイプの判定装置および方法 Download PDF

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JP6833703B2
JP6833703B2 JP2017544844A JP2017544844A JP6833703B2 JP 6833703 B2 JP6833703 B2 JP 6833703B2 JP 2017544844 A JP2017544844 A JP 2017544844A JP 2017544844 A JP2017544844 A JP 2017544844A JP 6833703 B2 JP6833703 B2 JP 6833703B2
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sample
conversion
test sample
whole blood
clot
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JP2017534069A5 (enExample
JP2017534069A (ja
Inventor
イーライ コーエン
イーライ コーエン
ガブリエル ラヴィヴ
ガブリエル ラヴィヴ
アイリーン ナヴィッカス
アイリーン ナヴィッカス
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コラ ヘルスケア インコーポレイテッド
コラ ヘルスケア インコーポレイテッド
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N29/00—Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic waves; Visualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object
    • G01N29/02—Analysing fluids
    • G01N29/036—Analysing fluids by measuring frequency or resonance of acoustic waves
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150755—Blood sample preparation for further analysis, e.g. by separating blood components or by mixing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/974—Thrombin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/22—Haematology
    • G01N2800/224—Haemostasis or coagulation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2871—Cerebrovascular disorders, e.g. stroke, cerebral infarct, cerebral haemorrhage, transient ischemic event

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Acoustics & Sound (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2017544844A 2014-11-14 2015-11-13 卒中サブタイプの判定装置および方法 Active JP6833703B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462079631P 2014-11-14 2014-11-14
US62/079,631 2014-11-14
PCT/US2015/060499 WO2016077657A1 (en) 2014-11-14 2015-11-13 Apparatus and method to determine stroke subtype

Related Child Applications (1)

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JP2020139188A Division JP7092831B2 (ja) 2014-11-14 2020-08-20 卒中サブタイプの判定装置および方法

Publications (3)

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JP2017534069A JP2017534069A (ja) 2017-11-16
JP2017534069A5 JP2017534069A5 (enExample) 2018-12-27
JP6833703B2 true JP6833703B2 (ja) 2021-02-24

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JP2017544844A Active JP6833703B2 (ja) 2014-11-14 2015-11-13 卒中サブタイプの判定装置および方法
JP2020139188A Active JP7092831B2 (ja) 2014-11-14 2020-08-20 卒中サブタイプの判定装置および方法

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Country Status (5)

Country Link
US (1) US12607641B2 (enExample)
EP (1) EP3218723B1 (enExample)
JP (2) JP6833703B2 (enExample)
CN (1) CN107438765B (enExample)
WO (1) WO2016077657A1 (enExample)

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5447440A (en) * 1993-10-28 1995-09-05 I-Stat Corporation Apparatus for assaying viscosity changes in fluid samples and method of conducting same
US6019735A (en) * 1997-08-28 2000-02-01 Visco Technologies, Inc. Viscosity measuring apparatus and method of use
US8076144B2 (en) * 1999-02-22 2011-12-13 Cora Healthcare, Inc. Protocol for risk stratification of ischemic events and optimized individualized treatment
US7144495B2 (en) * 2000-12-13 2006-12-05 Lifescan, Inc. Electrochemical test strip with an integrated micro-needle and associated methods
US20050153360A1 (en) * 2002-02-18 2005-07-14 Hochstrasser Denis F. Diagnostic method for stroke
US7261861B2 (en) 2003-04-24 2007-08-28 Haemoscope Corporation Hemostasis analyzer and method
CN101257908B (zh) 2005-04-20 2010-09-08 株式会社林原生物化学研究所 腹膜透析液
US20060269978A1 (en) * 2005-04-25 2006-11-30 Haworth William S Method and device for monitoring platelet function
US7879615B2 (en) 2005-10-20 2011-02-01 Coramed Technologies, Llc Hemostasis analyzer and method
US20090104637A1 (en) * 2006-01-31 2009-04-23 Ismagilov Rustem F Method and Apparatus for Assaying Blood Clotting
AU2010330861B2 (en) * 2009-12-18 2013-09-26 Entegrion, Inc. Portable coagulation monitoring device and method of assessing coagulation response
WO2011120556A1 (en) * 2010-03-30 2011-10-06 C A Casyso Ag Composition for the determination of coagulation characteristics of a test liquid
JP5992926B2 (ja) * 2011-02-10 2016-09-14 ザ クリーブランド クリニック ファウンデーションＴｈｅ Ｃｌｅｖｅｌａｎｄ ＣｌｉｎｉｃＦｏｕｎｄａｔｉｏｎ 心血管系疾患および血栓症の治療および予防のための組成物
JP2015503767A (ja) * 2012-01-16 2015-02-02 エイブラム サイエンティフィック，インコーポレーテッド 流体の物理的特性を測定するための方法、デバイス、およびシステム
ITUD20120028A1 (it) * 2012-02-21 2013-08-22 Sedicidodici S R L Camera di perfusione, relativa apparecchiatura utilizzante tale camera di perfusione e procedimento per l'analisi della patologia trombotico-ischemica ed emorragica
US20140142060A1 (en) * 2012-11-20 2014-05-22 Hyde Park West, LLC Method and device for identification of one carbon pathway gene variants as stroke risk markers, combined data mining, logistic regression, and pathway analysis
JP2016500443A (ja) * 2012-12-07 2016-01-12 ティー２ バイオシステムズ，インコーポレーテッド 強固な血餅形成をモニタリングするための方法
KR101481240B1 (ko) * 2012-12-27 2015-01-19 고려대학교 산학협력단 마이크로 유동칩 기반 혈소판 기능 및 약물반응 검사 장치 및 방법
US9068966B2 (en) * 2013-03-15 2015-06-30 Coramed Technologies, Llc Apparatus and cartridge for hemostasis testing

Also Published As

Publication number Publication date
JP7092831B2 (ja) 2022-06-28
US12607641B2 (en) 2026-04-21
CN107438765A (zh) 2017-12-05
WO2016077657A1 (en) 2016-05-19
EP3218723A1 (en) 2017-09-20
US20180238913A1 (en) 2018-08-23
CN107438765B (zh) 2022-07-26
JP2021001892A (ja) 2021-01-07
EP3218723B1 (en) 2021-10-06
JP2017534069A (ja) 2017-11-16

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