JP6830671B6 - γ−ヒドロキシ酪酸(GHB)のプロドラッグ、その組成物および使用 - Google Patents
γ−ヒドロキシ酪酸(GHB)のプロドラッグ、その組成物および使用 Download PDFInfo
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- JP6830671B6 JP6830671B6 JP2018533996A JP2018533996A JP6830671B6 JP 6830671 B6 JP6830671 B6 JP 6830671B6 JP 2018533996 A JP2018533996 A JP 2018533996A JP 2018533996 A JP2018533996 A JP 2018533996A JP 6830671 B6 JP6830671 B6 JP 6830671B6
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- 0 *N(C(CC1)C(OCCCC(O)=O)=O)C1=O Chemical compound *N(C(CC1)C(OCCCC(O)=O)=O)C1=O 0.000 description 3
- JCEIBJVFHBUCAV-UHFFFAOYSA-N CC(C)(C)OC(N(C)CC(OCCCC(OCc1ccccc1)=O)=O)=O Chemical compound CC(C)(C)OC(N(C)CC(OCCCC(OCc1ccccc1)=O)=O)=O JCEIBJVFHBUCAV-UHFFFAOYSA-N 0.000 description 1
- RJUAQNQYOWKPMP-UHFFFAOYSA-N CC(N(C)CC(OCCCC(O)=O)=O)=O Chemical compound CC(N(C)CC(OCCCC(O)=O)=O)=O RJUAQNQYOWKPMP-UHFFFAOYSA-N 0.000 description 1
- OKJIRPAQVSHGFK-UHFFFAOYSA-N CC(NCC(O)=O)=O Chemical compound CC(NCC(O)=O)=O OKJIRPAQVSHGFK-UHFFFAOYSA-N 0.000 description 1
- GTSLNFPEODYFCH-UHFFFAOYSA-N CC(NCC(OCCCC(O)=O)=O)=O Chemical compound CC(NCC(OCCCC(O)=O)=O)=O GTSLNFPEODYFCH-UHFFFAOYSA-N 0.000 description 1
- VQDNPPATZWTNER-UHFFFAOYSA-N CC(NCC(OCCCC(OCc1ccccc1)=O)=O)=O Chemical compound CC(NCC(OCCCC(OCc1ccccc1)=O)=O)=O VQDNPPATZWTNER-UHFFFAOYSA-N 0.000 description 1
- RTVSUZHDJGUDGX-UHFFFAOYSA-N CCOC(NCC(O)=O)=O Chemical compound CCOC(NCC(O)=O)=O RTVSUZHDJGUDGX-UHFFFAOYSA-N 0.000 description 1
- VXNFULZFIHHASV-UHFFFAOYSA-N CCOC(NCC(OCCCC(O)=O)=O)=O Chemical compound CCOC(NCC(OCCCC(O)=O)=O)=O VXNFULZFIHHASV-UHFFFAOYSA-N 0.000 description 1
- GJGTZLRGIADNCI-UHFFFAOYSA-N CCOCCCC[O](C(C1CCCCC1)=O)=C Chemical compound CCOCCCC[O](C(C1CCCCC1)=O)=C GJGTZLRGIADNCI-UHFFFAOYSA-N 0.000 description 1
- UEPNSASLESQQAC-UHFFFAOYSA-N CN(CC1)CCC1OC(OCCCC(O)=O)=O Chemical compound CN(CC1)CCC1OC(OCCCC(O)=O)=O UEPNSASLESQQAC-UHFFFAOYSA-N 0.000 description 1
- PDWGZJIXKJTADD-UHFFFAOYSA-N COC(c(cc1)ccc1C(OCCCCO)=O)=O Chemical compound COC(c(cc1)ccc1C(OCCCCO)=O)=O PDWGZJIXKJTADD-UHFFFAOYSA-N 0.000 description 1
- LQRFRYWTEBOKSP-UHFFFAOYSA-N COC(c1ccccc1C(OCCCC(O)=O)=O)=O Chemical compound COC(c1ccccc1C(OCCCC(O)=O)=O)=O LQRFRYWTEBOKSP-UHFFFAOYSA-N 0.000 description 1
- LAGQUZVODFVDCD-UHFFFAOYSA-N COc(cccc1)c1C(OCCCCO)=O Chemical compound COc(cccc1)c1C(OCCCCO)=O LAGQUZVODFVDCD-UHFFFAOYSA-N 0.000 description 1
- ZNEWWAHXAFHYNC-UHFFFAOYSA-N COc1cccc(C(OCCCC(O)=O)=O)c1OC Chemical compound COc1cccc(C(OCCCC(O)=O)=O)c1OC ZNEWWAHXAFHYNC-UHFFFAOYSA-N 0.000 description 1
- LHNBNPDZALUVHZ-UHFFFAOYSA-N CS(c1cc(C(OCCCC(O)=O)=O)ccc1)(=O)=O Chemical compound CS(c1cc(C(OCCCC(O)=O)=O)ccc1)(=O)=O LHNBNPDZALUVHZ-UHFFFAOYSA-N 0.000 description 1
- BEWIBXFFRNDHOC-YFKPBYRVSA-N C[C@@H](C(OCCCC(O)=O)=O)N Chemical compound C[C@@H](C(OCCCC(O)=O)=O)N BEWIBXFFRNDHOC-YFKPBYRVSA-N 0.000 description 1
- DDSADWSLXATZOA-UHFFFAOYSA-N Cc(cc1)ccc1C(OCCCCO)=O Chemical compound Cc(cc1)ccc1C(OCCCCO)=O DDSADWSLXATZOA-UHFFFAOYSA-N 0.000 description 1
- ZPXYJQOKQBYSIF-UHFFFAOYSA-N Cc1cc(C(OCCCCO)=O)cc(C)c1 Chemical compound Cc1cc(C(OCCCCO)=O)cc(C)c1 ZPXYJQOKQBYSIF-UHFFFAOYSA-N 0.000 description 1
- DEMDSXYFGBXTCF-UHFFFAOYSA-N Cc1ccc(CC(OCCCC(O)=O)=O)cc1 Chemical compound Cc1ccc(CC(OCCCC(O)=O)=O)cc1 DEMDSXYFGBXTCF-UHFFFAOYSA-N 0.000 description 1
- CRXCATWWXVJNJF-UHFFFAOYSA-N OCCCC(OCc1ccccc1)=O Chemical compound OCCCC(OCc1ccccc1)=O CRXCATWWXVJNJF-UHFFFAOYSA-N 0.000 description 1
- URMLGKUHPKEIQE-UHFFFAOYSA-N OCCCCOC(Oc(cc1)cc2c1OCO2)=O Chemical compound OCCCCOC(Oc(cc1)cc2c1OCO2)=O URMLGKUHPKEIQE-UHFFFAOYSA-N 0.000 description 1
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