JP6829201B2 - 医薬製剤 - Google Patents

医薬製剤 Download PDF

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Publication number
JP6829201B2
JP6829201B2 JP2017538226A JP2017538226A JP6829201B2 JP 6829201 B2 JP6829201 B2 JP 6829201B2 JP 2017538226 A JP2017538226 A JP 2017538226A JP 2017538226 A JP2017538226 A JP 2017538226A JP 6829201 B2 JP6829201 B2 JP 6829201B2
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pharmaceutical composition
aqueous pharmaceutical
injectable aqueous
composition according
injection
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JP2017538226A
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English (en)
Japanese (ja)
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JP2018502872A5 (enExample
JP2018502872A (ja
Inventor
マヘンドラ ジー. シャー,
マヘンドラ ジー. シャー,
Original Assignee
セムヌール ファーマシューティカルズ, インコーポレイテッド
セムヌール ファーマシューティカルズ, インコーポレイテッド
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/661Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0085Brain, e.g. brain implants; Spinal cord
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/04Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/06Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Inorganic Chemistry (AREA)
  • Psychology (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Steroid Compounds (AREA)
JP2017538226A 2015-01-21 2016-01-20 医薬製剤 Active JP6829201B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562106045P 2015-01-21 2015-01-21
US62/106,045 2015-01-21
PCT/US2016/014165 WO2016118649A1 (en) 2015-01-21 2016-01-20 Pharmaceutical formulation

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2020008235A Division JP7065129B2 (ja) 2015-01-21 2020-01-22 医薬製剤

Publications (3)

Publication Number Publication Date
JP2018502872A JP2018502872A (ja) 2018-02-01
JP2018502872A5 JP2018502872A5 (enExample) 2019-02-14
JP6829201B2 true JP6829201B2 (ja) 2021-02-10

Family

ID=55405453

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2017538226A Active JP6829201B2 (ja) 2015-01-21 2016-01-20 医薬製剤
JP2020008235A Active JP7065129B2 (ja) 2015-01-21 2020-01-22 医薬製剤
JP2021105585A Active JP7269992B2 (ja) 2015-01-21 2021-06-25 医薬製剤
JP2021143727A Pending JP2021183649A (ja) 2015-01-21 2021-09-03 医薬製剤

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2020008235A Active JP7065129B2 (ja) 2015-01-21 2020-01-22 医薬製剤
JP2021105585A Active JP7269992B2 (ja) 2015-01-21 2021-06-25 医薬製剤
JP2021143727A Pending JP2021183649A (ja) 2015-01-21 2021-09-03 医薬製剤

Country Status (13)

Country Link
US (4) US10500284B2 (enExample)
EP (2) EP3247329B3 (enExample)
JP (4) JP6829201B2 (enExample)
KR (2) KR102600792B1 (enExample)
CN (2) CN112957320A (enExample)
AU (1) AU2016209332B2 (enExample)
BR (1) BR112017015452B1 (enExample)
CA (1) CA2974657C (enExample)
ES (1) ES2877371T7 (enExample)
IL (1) IL253570B (enExample)
MX (2) MX386732B (enExample)
TW (3) TWI772659B (enExample)
WO (1) WO2016118649A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
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JP2020073576A (ja) * 2015-01-21 2020-05-14 セムヌール ファーマシューティカルズ, インコーポレイテッド 医薬製剤

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JP6215354B2 (ja) 2013-01-23 2017-10-18 セムヌール ファーマシューティカルズ, インコーポレイテッド 不溶性コルチコステロイドおよび可溶性コルチコステロイドを含む医薬処方物
US11857554B2 (en) * 2015-06-02 2024-01-02 Intravital Pty Ltd. Drug delivery device with pre-assembled cartridge
AU2019301542B2 (en) 2018-07-09 2025-04-03 Tlc Biopharmaceuticals, Inc. Methods to reduce complications of intra-articular steroid
IT201800010415A1 (it) * 2018-11-19 2020-05-19 Innate S R L Composizione iniettabile comprendente acido ialuronico e trealosio e uso della detta composizione.
CN112870155B (zh) * 2021-03-08 2023-06-30 上海昱聚科技有限公司 缓释地塞米松药物的凝胶注射剂及其制备方法和应用
WO2024159191A1 (en) * 2023-01-26 2024-08-02 Insignia Pharmaceuticals, Llc Pharmaceutical compositions for treating osteoarthritis
WO2025219919A1 (en) * 2024-04-19 2025-10-23 Beam Medical Inc. Anesthetic pharmaceutical compositions, kits and uses thereof for slow release of an anesthetic agent and concurrent medical imaging of its distribution

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020073576A (ja) * 2015-01-21 2020-05-14 セムヌール ファーマシューティカルズ, インコーポレイテッド 医薬製剤
JP7065129B2 (ja) 2015-01-21 2022-05-11 セムヌール ファーマシューティカルズ, インコーポレイテッド 医薬製剤

Also Published As

Publication number Publication date
US11020485B2 (en) 2021-06-01
KR20230157534A (ko) 2023-11-16
KR20170103974A (ko) 2017-09-13
BR112017015452A2 (pt) 2018-01-23
CN112957320A (zh) 2021-06-15
KR102600792B1 (ko) 2023-11-10
JP2020073576A (ja) 2020-05-14
IL253570A0 (en) 2017-09-28
US10500284B2 (en) 2019-12-10
WO2016118649A1 (en) 2016-07-28
TW201630609A (zh) 2016-09-01
HK1243932A1 (zh) 2018-07-27
US20180008714A1 (en) 2018-01-11
US20180185494A1 (en) 2018-07-05
IL253570B (en) 2020-08-31
EP3247329B1 (en) 2021-05-19
TWI772659B (zh) 2022-08-01
AU2016209332A1 (en) 2017-09-07
JP7065129B2 (ja) 2022-05-11
MX386732B (es) 2025-03-19
ES2877371T3 (es) 2021-11-16
US10117938B2 (en) 2018-11-06
KR102824858B1 (ko) 2025-06-26
US12285485B2 (en) 2025-04-29
US20200197523A1 (en) 2020-06-25
ES2877371T7 (es) 2022-05-24
BR112017015452B1 (pt) 2022-11-08
AU2016209332B2 (en) 2020-10-22
EP3247329A1 (en) 2017-11-29
CA2974657A1 (en) 2016-07-28
CN107205926A (zh) 2017-09-26
EP3925597A1 (en) 2021-12-22
HK1245653A1 (zh) 2018-08-31
JP2021183649A (ja) 2021-12-02
MX2017009482A (es) 2017-11-15
CA2974657C (en) 2024-02-20
JP2021143209A (ja) 2021-09-24
MX2021012029A (es) 2021-10-26
US20210386859A1 (en) 2021-12-16
CN107205926B (zh) 2021-03-05
EP3247329B3 (en) 2022-02-09
JP7269992B2 (ja) 2023-05-09
TW202005652A (zh) 2020-02-01
TW202245791A (zh) 2022-12-01
TWI674899B (zh) 2019-10-21
TWI845973B (zh) 2024-06-21
JP2018502872A (ja) 2018-02-01

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