JP6810146B2 - 受容体媒介化学療法による癌の治療のためのペプチド化合物およびペプチドコンジュゲート - Google Patents

受容体媒介化学療法による癌の治療のためのペプチド化合物およびペプチドコンジュゲート Download PDF

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JP6810146B2
JP6810146B2 JP2018527804A JP2018527804A JP6810146B2 JP 6810146 B2 JP6810146 B2 JP 6810146B2 JP 2018527804 A JP2018527804 A JP 2018527804A JP 2018527804 A JP2018527804 A JP 2018527804A JP 6810146 B2 JP6810146 B2 JP 6810146B2
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cancer
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JP2019501141A (ja
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ベリヴォー、リシャール
アンナビ、ボーレーヌ
デミュール、ミシェル
ラロック、アラン
− クリストフ カリー、ジャン
− クリストフ カリー、ジャン
シャルフィ、シンディア
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トランスフェール プリュ エス.ウ.セ.
トランスフェール プリュ エス.ウ.セ.
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    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
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    • A61K31/713Double-stranded nucleic acids or oligonucleotides
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    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
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    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5169Proteins, e.g. albumin, gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2018527804A 2015-11-24 2016-11-24 受容体媒介化学療法による癌の治療のためのペプチド化合物およびペプチドコンジュゲート Active JP6810146B2 (ja)

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US201562259178P 2015-11-24 2015-11-24
US62/259,178 2015-11-24
PCT/CA2016/051379 WO2017088058A1 (en) 2015-11-24 2016-11-24 Peptide compounds and peptide conjugates for the treatment of cancer through receptor-mediated chemotherapy

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JP2020135993A Division JP7095035B2 (ja) 2015-11-24 2020-08-11 受容体媒介化学療法による癌の治療のためのペプチド化合物およびペプチドコンジュゲート

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JP2019501141A5 JP2019501141A5 (enExample) 2019-12-26
JP6810146B2 true JP6810146B2 (ja) 2021-01-06

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JP2020135993A Active JP7095035B2 (ja) 2015-11-24 2020-08-11 受容体媒介化学療法による癌の治療のためのペプチド化合物およびペプチドコンジュゲート

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EP (2) EP3380495B1 (enExample)
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CA (2) CA3071494C (enExample)
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JP6810146B2 (ja) * 2015-11-24 2021-01-06 トランスフェール プリュ エス.ウ.セ. 受容体媒介化学療法による癌の治療のためのペプチド化合物およびペプチドコンジュゲート
EP3625245A4 (en) * 2017-05-24 2020-12-16 Transfert Plus, S.E.C. PEPTIDE COMPOUNDS, CONJUGATE COMPOUNDS AND THEIR USES IN THE TREATMENT OF INFLAMMATORY DISEASES
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AU2019324747A1 (en) * 2018-08-24 2021-04-01 Transfert Plus, S.E.C. Methods and compounds for targeting sortilin receptors and inhibiting vasculogenic mimicry
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CN120641133A (zh) * 2022-11-14 2025-09-12 瑟瑞技术公司 用于刺激抗肿瘤免疫应答的药物缀合物化合物
WO2025054707A1 (en) * 2023-09-11 2025-03-20 Theratechnologies Inc. Peptide conjugates of camptothecin analogs and uses thereof
CN117904303B (zh) * 2024-03-18 2024-06-18 湖南宏雅基因技术有限公司 Sorcs1基因甲基化和pax1基因甲基化联合诊断的检测引物探针组在制备宫颈癌诊断产品中的应用
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CA3006313A1 (en) 2017-06-01
EP3380495B1 (en) 2021-05-19
DK3380495T3 (da) 2021-08-16
JP2019501141A (ja) 2019-01-17
AU2021201085A1 (en) 2021-03-11
US20250296957A1 (en) 2025-09-25
JP2020189867A (ja) 2020-11-26
PT3380495T (pt) 2021-08-19
CA3071494C (en) 2021-12-14
SI3380495T1 (sl) 2022-01-31
AU2016358324B2 (en) 2021-03-11
CN116478245A (zh) 2023-07-25
AU2021201085B2 (en) 2023-01-19
BR112018010535A2 (pt) 2018-11-13
CN108473541A (zh) 2018-08-31
US11034727B2 (en) 2021-06-15
EP3925969A1 (en) 2021-12-22
US20200392184A1 (en) 2020-12-17
EP3380495A1 (en) 2018-10-03
EP3380495A4 (en) 2019-02-27
PL3380495T3 (pl) 2021-12-13
CA3071494A1 (en) 2017-06-01
JP7095035B2 (ja) 2022-07-04
EP3925969B1 (en) 2025-09-03
ES2882634T3 (es) 2021-12-02
WO2017088058A1 (en) 2017-06-01
ZA201804117B (en) 2022-08-31
US12269902B2 (en) 2025-04-08
US20240199695A1 (en) 2024-06-20
US20220356209A1 (en) 2022-11-10
US11780882B2 (en) 2023-10-10
CN108473541B (zh) 2023-05-12
CA3006313C (en) 2020-02-11
AU2016358324A1 (en) 2018-07-05
EP3925969C0 (en) 2025-09-03

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