JP6772431B2 - 高電圧アナログ回路パルサー及びパルス発生器の放電回路 - Google Patents
高電圧アナログ回路パルサー及びパルス発生器の放電回路 Download PDFInfo
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- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
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- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
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- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00773—Sensed parameters
- A61B2018/00875—Resistance or impedance
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- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00773—Sensed parameters
- A61B2018/00892—Voltage
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
- A61B2018/1405—Electrodes having a specific shape
- A61B2018/1425—Needle
- A61B2018/143—Needle multiple needles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
- A61B2018/1467—Probes or electrodes therefor using more than two electrodes on a single probe
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Description
本願は、「HIGH−VOLTAGE ANALOG CIRCUIT PULSER AND PULSE GENERATOR DISCHARGE CIRCUIT」と題する2016年11月9日に出願された米国特許出願第15/347,729号の継続出願であり、参照により本明細書に援用される「HIGH−VOLTAGE ANALOG CIRCUIT PULSER」と題する、2016年2月29日に出願された米国仮特許出願第62/301,477号の利益を主張する。
Claims (23)
- ナノ秒パルス電場(nsPEF)発生器であって、
直列に接続されている複数のパルス発生器段と、
入力信号パルスに応えて前記複数のパルス発生器段のために駆動信号パルスを発生させるように構成されたドライバ回路と、を備え、
前記複数のパルス発生器段のそれぞれが、
直列に接続された複数のスイッチを含むスイッチスタックと、
前記駆動信号パルスに応えて前記複数のスイッチを切り替えるために制御信号パルスを発生させるように構成された少なくとも1つのスイッチドライバと、を備え、
前記スイッチドライバの入力ポートが、前記ドライバ回路の出力ポートに結合され、
前記スイッチドライバの出力ポートが、前記複数のスイッチの前記それぞれのスイッチに結合され、
前記スイッチドライバの前記出力ポートが、変圧器を通して前記スイッチドライバの前記入力ポートに結合され、
容量性素子が、前記スイッチスタックに結合される、
前記ナノ秒パルス電場発生器。 - 前記複数のパルス発生器段のうちの少なくともいくつかが複数のスイッチドライバを備え、
各スイッチドライバが、前記複数のスイッチのうちのそれぞれのスイッチに対応し、前記駆動信号パルスに応えて前記それぞれのスイッチを切り替えるために制御信号パルスを発生させるように構成される、
請求項1に記載のnsPEF発生器。 - 抵抗素子をさらに備え、充電モード中、前記容量性素子が、前記抵抗素子を通って流れる電流により充電電圧まで充電される、
請求項1または2に記載のnsPEF発生器。 - 前記複数のパルス発生器段及び前記ドライバ回路がパルス発生器回路であるパネルを形成し、
前記nsPEF発生器が、並列に接続された複数のパネルを含む、
請求項1〜3のいずれか1項に記載のnsPEF発生器。 - 前記複数のパルス発生器段が5つ以下の段を含む、
請求項1〜4のいずれか1項に記載のnsPEF発生器。 - 前記複数のパルス発生器段のうちの少なくともいくつかが、5kVを超える振幅を有するパルスを発生させるように構成される、
請求項1〜5のいずれか1項に記載のnsPEF発生器。 - 前記変圧器が、損失の多い変圧器を含む、
請求項1〜6のいずれか1項に記載のnsPEF発生器。 - 前記変圧器が、100Vμs未満の電圧時間定数を有する、
請求項7に記載のnsPEF発生器。 - 前記変圧器が、
5巻き未満を有する一次巻線と、
5巻き未満を有する二次巻線と、を含む、
請求項1〜8のいずれか1項に記載のnsPEF発生器。 - 前記変圧器が、リセットを行う巻線なしの変圧器を含む、
請求項1〜9のいずれか1項に記載のnsPEF発生器。 - 前記複数のスイッチが、金属酸化物半導体電界効果トランジスタ(MOSFET)、サイリスタ、または絶縁ゲートバイポーラトランジスタ(IGBT)を含む、
請求項1〜10のいずれか1項に記載のnsPEF発生器。 - 前記複数のパルス発生器段のうちのそれぞれを選択的に放電するように構成された放電回路をさらに備える、
請求項1〜11のいずれか1項に記載のnsPEF発生器。 - 前記放電回路が、充電電圧と、前記パルス発生器段の前記容量性素子全体での電圧との差異に基づいてパルス発生器段を放電するように構成される、
請求項12に記載のnsPEF発生器。 - 前記放電回路が複数の放電段を含み、各放電段がパルス発生器段に対応する、
請求項12に記載のnsPEF発生器。 - 前記複数の放電段のうちの1つの放電段が、
直列に接続された複数の放電スイッチを含む放電スイッチスタックと、
パルス発生器段の前記容量性素子に前記放電スイッチスタックを接続する放電抵抗器と、を備える、
請求項14に記載のnsPEF発生器。 - 前記複数の放電段のうちの前記1つの放電段が、さらに
前記パルス発生器段の前記容量性素子全体での電圧に基づいてパルスを発生させるように構成されたパルス発生器と、
複数の変圧器であって、前記複数の変圧器の各変圧器が、前記パルス発生器及びそれぞれの放電スイッチに接続され、前記パルス発生器の出力に基づいて前記それぞれの放電スイッチのために制御信号を生成するように構成される、前記複数の変圧器と、を備える、
請求項15に記載のnsPEF発生器。 - 前記放電回路が、放電入力端子において受信される放電制御信号に応じて、前記複数のパルス発生器段のそれぞれに放電するように構成されている、請求項12に記載のnsPEF発生器。
- パルス発生器の作動方法であって、
ドライバ回路によって入力信号パルスを受け取ることと、
前記ドライバ回路によって、前記入力信号パルスに基づいて駆動信号パルスを発生させることと、
複数の直列接続されたパルス発生器段の各パルス発生器段によって、及び前記駆動信号パルスに基づいて、
前記パルス発生器段の容量性素子を充電すること、及び
複数のスイッチを切り替えて前記容量性素子を電極を通して放電するために、少なくとも1つのスイッチドライバによって及び前記駆動信号パルスに基づいて、制御信号パルスを発生させること
によって、前記駆動信号パルスよりも高い振幅を有する出力パルスを発生させることと、を含み、
前記複数のスイッチが直列に接続されてスイッチスタックを形成し、
前記少なくとも1つのスイッチドライバが、前記駆動信号パルスを前記制御信号パルスに変換する変圧器を含む、
前記方法。 - 前記複数のスイッチを切り替えるために前記制御信号パルスを発生させることが、
前記少なくとも1つのスイッチドライバによって、前記複数のスイッチのそれぞれのスイッチを切り替えるために制御信号パルスを発生させること、を含む、
請求項18に記載の方法。 - 前記制御信号パルスの最大幅、前記複数のスイッチの最大ターンオン時間、及び前記出力パルスの最大パルス幅がナノ秒範囲内である、
請求項18または19に記載の方法。 - 充電電圧と、前記対応するパルス発生器段の前記容量性素子全体での電圧との差異に基づいて前記複数の直列に接続されたパルス発生器段の各パルス発生器段を選択的に放電すること、をさらに含む、
請求項18〜20のいずれか1項に記載の方法。 - 各パルス発生器段を選択的に放電することが、放電抵抗器を通して放電スイッチスタックによって前記容量性素子を放電することを含む、
請求項21に記載の方法。 - 前記放電スイッチスタックによって前記容量性素子を放電することが、
複数の変圧器のうちの1つの変圧器によって、前記放電スイッチスタックのそれぞれの放電スイッチのために制御信号を生成することと、を含む、
請求項22に記載の方法。
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Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662301477P | 2016-02-29 | 2016-02-29 | |
US62/301,477 | 2016-02-29 | ||
US15/347,729 US10874451B2 (en) | 2016-02-29 | 2016-11-09 | High-voltage analog circuit pulser and pulse generator discharge circuit |
US15/347,729 | 2016-11-09 | ||
PCT/US2017/015881 WO2017151260A1 (en) | 2016-02-29 | 2017-01-31 | High-voltage analog circuit pulser and pulse generator discharge circuit |
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JP2019506950A JP2019506950A (ja) | 2019-03-14 |
JP6772431B2 true JP6772431B2 (ja) | 2020-10-21 |
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EP (1) | EP3424145A4 (ja) |
JP (1) | JP6772431B2 (ja) |
KR (1) | KR102212539B1 (ja) |
CN (1) | CN108702146B (ja) |
AU (2) | AU2017225296B2 (ja) |
CA (1) | CA3015754C (ja) |
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WO (1) | WO2017151260A1 (ja) |
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