JP6769992B2 - ポリマーナノ粒子における感光性化合物を含む組成物およびその組成物を使用する方法 - Google Patents

ポリマーナノ粒子における感光性化合物を含む組成物およびその組成物を使用する方法 Download PDF

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JP6769992B2
JP6769992B2 JP2017555716A JP2017555716A JP6769992B2 JP 6769992 B2 JP6769992 B2 JP 6769992B2 JP 2017555716 A JP2017555716 A JP 2017555716A JP 2017555716 A JP2017555716 A JP 2017555716A JP 6769992 B2 JP6769992 B2 JP 6769992B2
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cancer
nanoparticles
sinc
polymer
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JP2018513875A5 (enExample
JP2018513875A (ja
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タラチュラ、オレナ
タラチュラ、オレフ
アラニ、アダム
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オレゴン ステート ユニヴァーシティ
オレゴン ステート ユニヴァーシティ
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/409—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having four such rings, e.g. porphine derivatives, bilirubin, biliverdine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0036—Porphyrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0063—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
    • A61K49/0069—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form
    • A61K49/0089—Particulate, powder, adsorbate, bead, sphere
    • A61K49/0091—Microparticle, microcapsule, microbubble, microsphere, microbead, i.e. having a size or diameter higher or equal to 1 micrometer
    • A61K49/0093—Nanoparticle, nanocapsule, nanobubble, nanosphere, nanobead, i.e. having a size or diameter smaller than 1 micrometer, e.g. polymeric nanoparticle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nanotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2017555716A 2015-04-20 2016-04-18 ポリマーナノ粒子における感光性化合物を含む組成物およびその組成物を使用する方法 Active JP6769992B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562150125P 2015-04-20 2015-04-20
US62/150,125 2015-04-20
PCT/US2016/028113 WO2016172046A1 (en) 2015-04-20 2016-04-18 A composition comprising a photosensitive compound in a polymeric nanoparticle, and a method of using the composition

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JP2018513875A JP2018513875A (ja) 2018-05-31
JP2018513875A5 JP2018513875A5 (enExample) 2019-06-06
JP6769992B2 true JP6769992B2 (ja) 2020-10-14

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US (1) US10646472B2 (enExample)
EP (1) EP3285765B1 (enExample)
JP (1) JP6769992B2 (enExample)
CN (1) CN107613975B (enExample)
CA (1) CA2981614C (enExample)
WO (2) WO2016172046A1 (enExample)

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EP3285765B1 (en) * 2015-04-20 2020-04-08 Oregon State University A composition comprising a photosensitive compound in a polymeric nanoparticle, and a method of using the composition
CN107789623B (zh) * 2017-11-09 2020-12-15 福州大学 哌嗪取代硅酞菁及其在光热治疗中的应用
RU2020132481A (ru) * 2018-03-30 2022-05-04 Торэй Индастриз, Инк. Биоразлагаемый блок-сополимер
US20210268129A1 (en) * 2018-06-22 2021-09-02 The Governers Of The University Of Alberta Theranostic Radiophotodynamic Therapy Nanoparticles
JP7371476B2 (ja) * 2018-12-13 2023-10-31 東洋インキＳｃホールディングス株式会社 近赤外蛍光組成物および近赤外蛍光標識剤
WO2020132980A1 (zh) * 2018-12-26 2020-07-02 深圳先进技术研究院 细菌-光热纳米颗粒复合物及制备方法和应用
JP2022530823A (ja) * 2019-05-02 2022-07-01 ザ・ユニバーシティ・オブ・シドニー がん治療のためのペプチド誘導体とそのコンジュゲート
CN115802930A (zh) * 2020-06-30 2023-03-14 强生消费者公司 用于使用示踪剂控制针对皮肤病症的治疗的装置和方法
CN116634925A (zh) 2020-08-03 2023-08-22 强生消费者公司 选择性施用化妆品组合物以赋予眼下亮白的系统和方法
CN112972690B (zh) * 2021-02-22 2022-12-23 上海交通大学医学院附属第九人民医院 一种基于三角纳米金载体、制备方法及用途
CN113368235B (zh) * 2021-05-11 2022-11-15 上海师范大学 一种Gd-NGQDs/BTS@PLGA-PEG纳米材料及其制备方法和应用
US20240424147A1 (en) * 2021-10-05 2024-12-26 The Trustees Of The University Of Pennsylvania Phthalocyanine-loaded micelles for the direct visualization of tumors
CN116637209B (zh) * 2023-05-18 2024-06-07 南京溯远基因科技有限公司 一种荧光染料复合物及其制备方法

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US6635740B1 (en) 1997-03-27 2003-10-21 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Ligand/lytic peptide compositions and methods of use
JP2010083860A (ja) * 2008-02-29 2010-04-15 Kyoto Univ ポリマーナノ微粒子及び光分子イメージング用造影剤
IT1391530B1 (it) * 2008-07-31 2012-01-11 Cyanagen S R L Particelle attive per applicazioni bio-analitiche e metodi per la loro preparazione
WO2013012628A2 (en) 2011-07-15 2013-01-24 The University Of Georgia Research Foundation, Inc. Immune-stimulating photoactive hybrid nanoparticles
US8974830B2 (en) * 2012-02-23 2015-03-10 Canon Kabushiki Kaisha Particles and contrast agent including the same for optical imaging
US20130336889A1 (en) * 2012-06-14 2013-12-19 National Taiwan University Nanoparticle and method for detecting or treating a tumor using the same
WO2015026963A2 (en) * 2013-08-21 2015-02-26 Oregon State University Phthalocy anine-dendrimer compositions and a method of using
EP3285765B1 (en) * 2015-04-20 2020-04-08 Oregon State University A composition comprising a photosensitive compound in a polymeric nanoparticle, and a method of using the composition
ES2992591T3 (en) 2015-08-18 2024-12-16 Rakuten Medical Inc Compositions, combinations and related methods for photoimmunotherapy

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Publication number Publication date
WO2019079201A3 (en) 2019-05-31
WO2019079201A2 (en) 2019-04-25
US10646472B2 (en) 2020-05-12
EP3285765B1 (en) 2020-04-08
US20180028496A1 (en) 2018-02-01
CA2981614C (en) 2023-09-05
CA2981614A1 (en) 2016-10-27
EP3285765A4 (en) 2018-12-05
WO2016172046A1 (en) 2016-10-27
CN107613975B (zh) 2021-08-03
EP3285765A1 (en) 2018-02-28
CN107613975A (zh) 2018-01-19
JP2018513875A (ja) 2018-05-31

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