JP6768662B2 - Nadphオキシダーゼに関連する状態の処置に使用するための化合物 - Google Patents
Nadphオキシダーゼに関連する状態の処置に使用するための化合物 Download PDFInfo
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- JP6768662B2 JP6768662B2 JP2017532057A JP2017532057A JP6768662B2 JP 6768662 B2 JP6768662 B2 JP 6768662B2 JP 2017532057 A JP2017532057 A JP 2017532057A JP 2017532057 A JP2017532057 A JP 2017532057A JP 6768662 B2 JP6768662 B2 JP 6768662B2
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- QCWUZEVYHRNXTA-UHFFFAOYSA-N Cc(cc1C)cc(C)c1S(NCCC1C=CC=CC1)(O)=O Chemical compound Cc(cc1C)cc(C)c1S(NCCC1C=CC=CC1)(O)=O QCWUZEVYHRNXTA-UHFFFAOYSA-N 0.000 description 1
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- A61K31/00—Medicinal preparations containing organic active ingredients
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- A61K31/18—Sulfonamides
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Endocrinology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Obesity (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Vascular Medicine (AREA)
- Rheumatology (AREA)
- Oncology (AREA)
- Physical Education & Sports Medicine (AREA)
- Communicable Diseases (AREA)
- Ophthalmology & Optometry (AREA)
- Emergency Medicine (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14198240.5 | 2014-12-16 | ||
| EP14198240 | 2014-12-16 | ||
| PCT/EP2015/079586 WO2016096720A1 (en) | 2014-12-16 | 2015-12-14 | Compounds for use in the treatment of conditions associated with nadph oxidase |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018500324A JP2018500324A (ja) | 2018-01-11 |
| JP2018500324A5 JP2018500324A5 (enExample) | 2019-01-24 |
| JP6768662B2 true JP6768662B2 (ja) | 2020-10-14 |
Family
ID=52133887
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017532057A Active JP6768662B2 (ja) | 2014-12-16 | 2015-12-14 | Nadphオキシダーゼに関連する状態の処置に使用するための化合物 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US10195167B2 (enExample) |
| EP (1) | EP3233072A1 (enExample) |
| JP (1) | JP6768662B2 (enExample) |
| CN (1) | CN107405318A (enExample) |
| CA (1) | CA2969051C (enExample) |
| WO (1) | WO2016096720A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2857957T3 (es) | 2016-10-06 | 2021-09-29 | Basf Se | Procedimiento de enriquecimiento de enantiómeros a partir de una mezcla de enantiómeros |
| JP7455762B2 (ja) * | 2018-05-09 | 2024-03-26 | グルソックス・バイオテック・アーベー | 選択的なNox阻害活性を有する新規のスルホンアミド誘導体 |
| CN118178506B (zh) * | 2024-03-18 | 2025-09-12 | 山东中医药大学附属医院 | 升麻提取物、灵芝多糖和nadph联合使用在制备治疗重症脓毒症药物中的用途 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007536348A (ja) | 2004-05-05 | 2007-12-13 | ノボ ノルディスク アクティーゼルスカブ | スルホンアミド誘導体 |
| US8071631B2 (en) * | 2006-08-16 | 2011-12-06 | The J. David Gladstone Institutes, A Testamentary Trust Established Under The Will Of J. David Gladstone | Small molecule inhibitors of kynurenine-3-monooxygenase |
| CN101817767A (zh) * | 2009-02-26 | 2010-09-01 | 中国科学院上海药物研究所 | 取代磺酰胺类化合物及其制备方法、药物组合物和应用 |
| KR101298651B1 (ko) * | 2011-03-16 | 2013-08-21 | 연세대학교 산학협력단 | 효능이 강화된 혈관신생 억제용 약제학적 조성물 |
| ES2863538T3 (es) * | 2012-09-20 | 2021-10-11 | Univ Temple | Derivados de alquil diarilo sustituidos, métodos de preparación y usos |
| US9687490B2 (en) * | 2012-10-24 | 2017-06-27 | Glucox Biotech Ab | Triazine derivatives for the treatment of conditions associated with nicotinamide adenine dinucleotide phosphate oxidase |
-
2015
- 2015-12-14 WO PCT/EP2015/079586 patent/WO2016096720A1/en not_active Ceased
- 2015-12-14 CN CN201580069060.1A patent/CN107405318A/zh active Pending
- 2015-12-14 EP EP15808420.2A patent/EP3233072A1/en active Pending
- 2015-12-14 JP JP2017532057A patent/JP6768662B2/ja active Active
- 2015-12-14 CA CA2969051A patent/CA2969051C/en active Active
- 2015-12-14 US US15/535,524 patent/US10195167B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CA2969051C (en) | 2023-12-12 |
| CA2969051A1 (en) | 2016-06-23 |
| US10195167B2 (en) | 2019-02-05 |
| EP3233072A1 (en) | 2017-10-25 |
| WO2016096720A1 (en) | 2016-06-23 |
| JP2018500324A (ja) | 2018-01-11 |
| US20180271810A1 (en) | 2018-09-27 |
| CN107405318A (zh) | 2017-11-28 |
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