JP6768662B2 - Nadphオキシダーゼに関連する状態の処置に使用するための化合物 - Google Patents

Nadphオキシダーゼに関連する状態の処置に使用するための化合物 Download PDF

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JP6768662B2
JP6768662B2 JP2017532057A JP2017532057A JP6768662B2 JP 6768662 B2 JP6768662 B2 JP 6768662B2 JP 2017532057 A JP2017532057 A JP 2017532057A JP 2017532057 A JP2017532057 A JP 2017532057A JP 6768662 B2 JP6768662 B2 JP 6768662B2
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JP2018500324A5 (enExample
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ヴィクストレェム,ペル
ヴァルム,エリク
ヴィルケ,モーナ
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グルソックス・バイオテック・アーベー
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/18Sulfonamides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P25/00Drugs for disorders of the nervous system
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    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Vascular Medicine (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Communicable Diseases (AREA)
  • Ophthalmology & Optometry (AREA)
  • Emergency Medicine (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2017532057A 2014-12-16 2015-12-14 Nadphオキシダーゼに関連する状態の処置に使用するための化合物 Active JP6768662B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14198240.5 2014-12-16
EP14198240 2014-12-16
PCT/EP2015/079586 WO2016096720A1 (en) 2014-12-16 2015-12-14 Compounds for use in the treatment of conditions associated with nadph oxidase

Publications (3)

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JP2018500324A JP2018500324A (ja) 2018-01-11
JP2018500324A5 JP2018500324A5 (enExample) 2019-01-24
JP6768662B2 true JP6768662B2 (ja) 2020-10-14

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JP2017532057A Active JP6768662B2 (ja) 2014-12-16 2015-12-14 Nadphオキシダーゼに関連する状態の処置に使用するための化合物

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US (1) US10195167B2 (enExample)
EP (1) EP3233072A1 (enExample)
JP (1) JP6768662B2 (enExample)
CN (1) CN107405318A (enExample)
CA (1) CA2969051C (enExample)
WO (1) WO2016096720A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2857957T3 (es) 2016-10-06 2021-09-29 Basf Se Procedimiento de enriquecimiento de enantiómeros a partir de una mezcla de enantiómeros
JP7455762B2 (ja) * 2018-05-09 2024-03-26 グルソックス・バイオテック・アーベー 選択的なNox阻害活性を有する新規のスルホンアミド誘導体
CN118178506B (zh) * 2024-03-18 2025-09-12 山东中医药大学附属医院 升麻提取物、灵芝多糖和nadph联合使用在制备治疗重症脓毒症药物中的用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007536348A (ja) 2004-05-05 2007-12-13 ノボ ノルディスク アクティーゼルスカブ スルホンアミド誘導体
US8071631B2 (en) * 2006-08-16 2011-12-06 The J. David Gladstone Institutes, A Testamentary Trust Established Under The Will Of J. David Gladstone Small molecule inhibitors of kynurenine-3-monooxygenase
CN101817767A (zh) * 2009-02-26 2010-09-01 中国科学院上海药物研究所 取代磺酰胺类化合物及其制备方法、药物组合物和应用
KR101298651B1 (ko) * 2011-03-16 2013-08-21 연세대학교 산학협력단 효능이 강화된 혈관신생 억제용 약제학적 조성물
ES2863538T3 (es) * 2012-09-20 2021-10-11 Univ Temple Derivados de alquil diarilo sustituidos, métodos de preparación y usos
US9687490B2 (en) * 2012-10-24 2017-06-27 Glucox Biotech Ab Triazine derivatives for the treatment of conditions associated with nicotinamide adenine dinucleotide phosphate oxidase

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Publication number Publication date
CA2969051C (en) 2023-12-12
CA2969051A1 (en) 2016-06-23
US10195167B2 (en) 2019-02-05
EP3233072A1 (en) 2017-10-25
WO2016096720A1 (en) 2016-06-23
JP2018500324A (ja) 2018-01-11
US20180271810A1 (en) 2018-09-27
CN107405318A (zh) 2017-11-28

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