JP6749917B2 - ｉＦＲ−ＣＴ - Google Patents

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JP6749917B2
JP6749917B2 JP2017536523A JP2017536523A JP6749917B2 JP 6749917 B2 JP6749917 B2 JP 6749917B2 JP 2017536523 A JP2017536523 A JP 2017536523A JP 2017536523 A JP2017536523 A JP 2017536523A JP 6749917 B2 JP6749917 B2 JP 6749917B2
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resistance
stenosis
outlet
blood vessel
image data
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JP2018501894A5 (enExample
JP2018501894A (ja
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リラン ゴシェン
リラン ゴシェン
イェチェル ラマッシュ
イェチェル ラマッシュ
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Koninklijke Philips NV
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/50—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications
    • A61B6/507—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications for determination of haemodynamic parameters, e.g. perfusion CT
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/50—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications
    • A61B6/504—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications for diagnosis of blood vessels, e.g. by angiography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/02007—Evaluating blood vessel condition, e.g. elasticity, compliance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7271—Specific aspects of physiological measurement analysis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/02—Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
    • A61B6/03—Computed tomography [CT]
    • A61B6/032—Transmission computed tomography [CT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/52—Devices using data or image processing specially adapted for radiation diagnosis
    • A61B6/5211—Devices using data or image processing specially adapted for radiation diagnosis involving processing of medical diagnostic data
    • A61B6/5217—Devices using data or image processing specially adapted for radiation diagnosis involving processing of medical diagnostic data extracting a diagnostic or physiological parameter from medical diagnostic data
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/60—Analysis of geometric attributes
    • G06T7/62—Analysis of geometric attributes of area, perimeter, diameter or volume
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H30/00—ICT specially adapted for the handling or processing of medical images
    • G16H30/20—ICT specially adapted for the handling or processing of medical images for handling medical images, e.g. DICOM, HL7 or PACS
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/30—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/02028—Determining haemodynamic parameters not otherwise provided for, e.g. cardiac contractility or left ventricular ejection fraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/026—Measuring blood flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/02—Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
    • A61B6/03—Computed tomography [CT]
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10072—Tomographic images
    • G06T2207/10081—Computed x-ray tomography [CT]
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30101—Blood vessel; Artery; Vein; Vascular
    • G06T2207/30104—Vascular flow; Blood flow; Perfusion
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/50—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medical Informatics (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Optics & Photonics (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Physiology (AREA)
  • Vascular Medicine (AREA)
  • Theoretical Computer Science (AREA)
  • Dentistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • General Physics & Mathematics (AREA)
  • Primary Health Care (AREA)
  • Epidemiology (AREA)
  • Artificial Intelligence (AREA)
  • Psychiatry (AREA)
  • Signal Processing (AREA)
  • Cardiology (AREA)
  • Quality & Reliability (AREA)
  • Geometry (AREA)
  • Pulmonology (AREA)
  • Databases & Information Systems (AREA)
  • Data Mining & Analysis (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
JP2017536523A 2015-01-15 2016-01-06 ｉＦＲ−ＣＴ Active JP6749917B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562103721P 2015-01-15 2015-01-15
US62/103,721 2015-01-15
PCT/IB2016/050043 WO2016113646A1 (en) 2015-01-15 2016-01-06 Ifr-ct

Publications (3)

Publication Number Publication Date
JP2018501894A JP2018501894A (ja) 2018-01-25
JP2018501894A5 JP2018501894A5 (enExample) 2019-02-07
JP6749917B2 true JP6749917B2 (ja) 2020-09-02

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JP2017536523A Active JP6749917B2 (ja) 2015-01-15 2016-01-06 ｉＦＲ−ＣＴ

Country Status (5)

Country Link
US (1) US10646185B2 (enExample)
EP (1) EP3244790B1 (enExample)
JP (1) JP6749917B2 (enExample)
CN (1) CN107580470B (enExample)
WO (1) WO2016113646A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3518751B1 (en) * 2016-09-30 2025-01-29 Koninklijke Philips N.V. Apparatus for determining a functional index for stenosis assessment
CN109770888A (zh) * 2019-03-19 2019-05-21 苏州润迈德医疗科技有限公司 基于压力传感器和造影图像计算瞬时无波形比率的方法
CN109616200A (zh) * 2018-11-06 2019-04-12 北京三普威盛科技有限公司 用于冠脉狭窄评估的方法，装置，存储介质及电子设备
CN111166315B (zh) * 2018-11-13 2023-03-28 苏州润迈德医疗科技有限公司 基于造影图像计算瞬时无波型比率和静息态舒张期压力比率的方法
CN111166316B (zh) * 2018-11-13 2023-03-21 苏州润迈德医疗科技有限公司 基于造影图像计算造影瞬时无波型比率和造影舒张期压力比率的方法
WO2020142789A1 (en) * 2019-01-06 2020-07-09 Covanos, Inc. Noninvasive determination of resting state diastole hemodynamic information
US10861157B2 (en) 2019-04-04 2020-12-08 Medtronic Vascular, Inc. System and methods for determining modified fractional flow reserve values
CN110353645A (zh) * 2019-08-19 2019-10-22 苏州润迈德医疗科技有限公司 测量无波形期压力、比率方法、装置、系统及存储介质

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5085800A (en) 1999-05-21 2000-12-12 Nycomed Imaging As Method of magnetic resonance imaging
DE10049549A1 (de) * 2000-10-06 2002-05-02 Markus Hecker Modulation der Transkription pro-inflammatorischer Genprodukte
GB0221434D0 (en) 2002-09-16 2002-10-23 Houston John G A method of analysing fluid flow in a conduit
IL165636A0 (en) 2004-12-08 2006-01-15 Paieon Inc Method and apparatus for finding the coronary velocity and flow and related parameters
EP1830701A1 (en) 2004-12-08 2007-09-12 Paieon Inc. Method and apparatus for blood vessel parameter determinations
US8052611B2 (en) 2007-03-14 2011-11-08 Cardiac Pacemakers, Inc. Method and apparatus for management of heart failure hospitalization
WO2009051731A1 (en) * 2007-10-15 2009-04-23 Harbert Richard H Even fire 90° v12 ic engines, fueling and firing sequence controllers, and methods of operation by ps/p technology and ifr compensation by fuel feed control
JP2011521618A (ja) * 2008-02-04 2011-07-28 バイパー サイエンシズ，インコーポレイティド Ｐａｒｐ仲介疾患を診断および治療する方法
DE102008014792B3 (de) 2008-03-18 2009-06-18 Siemens Aktiengesellschaft Verfahren und Vorrichtung zur Simulation eines Blutflusses in einem Gefäßabschnitt
US8200466B2 (en) 2008-07-21 2012-06-12 The Board Of Trustees Of The Leland Stanford Junior University Method for tuning patient-specific cardiovascular simulations
US8898022B2 (en) 2008-08-25 2014-11-25 Eth Zurich Method, system and device for enhancing flow field data
US8908939B2 (en) 2008-09-30 2014-12-09 Koninklijke Philips N.V. Perfusion imaging
US20100125197A1 (en) 2008-11-18 2010-05-20 Fishel Robert S Method and apparatus for addressing vascular stenotic lesions
US20100130878A1 (en) 2008-11-24 2010-05-27 General Electric Company Systems, apparatus and processes for automated blood flow assessment of vasculature
KR101100551B1 (ko) * 2008-12-17 2011-12-29 삼성메디슨 주식회사 클러터 신호를 필터링하는 초음파 시스템 및 방법
US9405886B2 (en) 2009-03-17 2016-08-02 The Board Of Trustees Of The Leland Stanford Junior University Method for determining cardiovascular information
WO2011038044A2 (en) * 2009-09-23 2011-03-31 Lightlab Imaging, Inc. Lumen morphology and vascular resistance measurements data collection systems, apparatus and methods
US20110307231A1 (en) 2010-06-09 2011-12-15 Jens Kirchner Method and arrangement for creating an individualized, computer-aided model of a system, and a corresponding computer program and a corresponding machine-readable storage medium
CN101847208B (zh) * 2010-06-11 2012-06-06 哈尔滨工程大学 指纹与指静脉双模态识别的二级分类融合识别方法
US8682626B2 (en) 2010-07-21 2014-03-25 Siemens Aktiengesellschaft Method and system for comprehensive patient-specific modeling of the heart
US8315812B2 (en) 2010-08-12 2012-11-20 Heartflow, Inc. Method and system for patient-specific modeling of blood flow
US8157742B2 (en) * 2010-08-12 2012-04-17 Heartflow, Inc. Method and system for patient-specific modeling of blood flow
US9119540B2 (en) 2010-09-16 2015-09-01 Siemens Aktiengesellschaft Method and system for non-invasive assessment of coronary artery disease
DE102010043849B3 (de) 2010-11-12 2012-02-16 Siemens Aktiengesellschaft Vorrichtung und Computertomograph zur Bestimmung und Darstellung der Durchblutung des Herzmuskels
US10186056B2 (en) 2011-03-21 2019-01-22 General Electric Company System and method for estimating vascular flow using CT imaging
US20120296199A1 (en) 2011-03-21 2012-11-22 New York University Apparatus and Method of Non-Contrast Magnetic Resonance Angiography of Abdominal and Pelvic Arteries
US9135699B2 (en) * 2012-03-15 2015-09-15 Siemens Aktiengesellschaft Method and system for hemodynamic assessment of aortic coarctation from medical image data
BR112014028143A2 (pt) 2012-05-14 2017-06-27 Koninklijke Philips Nv sistema e meio de armazenamento legível por computador
JP6134789B2 (ja) * 2012-06-26 2017-05-24 シンク−アールエックス，リミティド 管腔器官における流れに関連する画像処理
US10398386B2 (en) * 2012-09-12 2019-09-03 Heartflow, Inc. Systems and methods for estimating blood flow characteristics from vessel geometry and physiology
US9675301B2 (en) 2012-10-19 2017-06-13 Heartflow, Inc. Systems and methods for numerically evaluating vasculature
EP2916735B1 (en) * 2012-11-06 2019-09-25 Koninklijke Philips N.V. Fractional flow reserve (ffr) index
US9424395B2 (en) 2013-03-04 2016-08-23 Heartflow, Inc. Method and system for sensitivity analysis in modeling blood flow characteristics
US20140276137A1 (en) 2013-03-14 2014-09-18 Volcano Corporation Systems and methods for determining coronary flow reserve
CN204089830U (zh) * 2014-02-25 2015-01-07 捷荣航材(广州)有限公司 一种vhf收发机综合试验装置
US9595089B2 (en) * 2014-05-09 2017-03-14 Siemens Healthcare Gmbh Method and system for non-invasive computation of hemodynamic indices for coronary artery stenosis
US9747525B2 (en) * 2014-06-16 2017-08-29 Siemens Healthcare Gmbh Method and system for improved hemodynamic computation in coronary arteries
CN106659400B (zh) * 2014-06-30 2021-01-05 皇家飞利浦有限公司 用于确定血流储备分数值的装置
US10130266B2 (en) * 2014-06-30 2018-11-20 Siemens Healthcare Gmbh Method and system for prediction of post-stenting hemodynamic metrics for treatment planning of arterial stenosis
US9888968B2 (en) * 2014-07-22 2018-02-13 Siemens Healthcare Gmbh Method and system for automated therapy planning for arterial stenosis

Also Published As

Publication number Publication date
EP3244790B1 (en) 2020-09-02
US10646185B2 (en) 2020-05-12
WO2016113646A1 (en) 2016-07-21
CN107580470A (zh) 2018-01-12
US20180271468A1 (en) 2018-09-27
CN107580470B (zh) 2021-06-22
JP2018501894A (ja) 2018-01-25
EP3244790A1 (en) 2017-11-22

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