JP6682430B2 - 風味前駆体を含む喫煙用組成物 - Google Patents
風味前駆体を含む喫煙用組成物 Download PDFInfo
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- JP6682430B2 JP6682430B2 JP2016522111A JP2016522111A JP6682430B2 JP 6682430 B2 JP6682430 B2 JP 6682430B2 JP 2016522111 A JP2016522111 A JP 2016522111A JP 2016522111 A JP2016522111 A JP 2016522111A JP 6682430 B2 JP6682430 B2 JP 6682430B2
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- 239000000796 flavoring agent Substances 0.000 title claims description 198
- 235000019634 flavors Nutrition 0.000 title claims description 158
- 230000000391 smoking effect Effects 0.000 title claims description 132
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- 239000000203 mixture Substances 0.000 title description 51
- 150000001875 compounds Chemical class 0.000 claims description 130
- 235000002637 Nicotiana tabacum Nutrition 0.000 claims description 80
- 241000208125 Nicotiana Species 0.000 claims description 78
- 239000000758 substrate Substances 0.000 claims description 58
- 238000010438 heat treatment Methods 0.000 claims description 27
- 150000003573 thiols Chemical class 0.000 claims description 15
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 claims description 13
- 229960002715 nicotine Drugs 0.000 claims description 13
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 claims description 13
- ZFFTZDQKIXPDAF-UHFFFAOYSA-N 2-Furanmethanethiol Chemical compound SCC1=CC=CO1 ZFFTZDQKIXPDAF-UHFFFAOYSA-N 0.000 claims description 3
- 238000000034 method Methods 0.000 description 28
- 235000019504 cigarettes Nutrition 0.000 description 27
- 239000000443 aerosol Substances 0.000 description 26
- RWSXRVCMGQZWBV-WDSKDSINSA-N glutathione Chemical compound OC(=O)[C@@H](N)CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O RWSXRVCMGQZWBV-WDSKDSINSA-N 0.000 description 13
- LSDPWZHWYPCBBB-UHFFFAOYSA-N Methanethiol Chemical compound SC LSDPWZHWYPCBBB-UHFFFAOYSA-N 0.000 description 12
- 230000008569 process Effects 0.000 description 12
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- 229910052799 carbon Inorganic materials 0.000 description 11
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- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 10
- 125000000539 amino acid group Chemical group 0.000 description 10
- 239000000543 intermediate Substances 0.000 description 10
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- 235000018417 cysteine Nutrition 0.000 description 9
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 description 9
- 229910052739 hydrogen Inorganic materials 0.000 description 9
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- 239000007788 liquid Substances 0.000 description 8
- 239000000463 material Substances 0.000 description 8
- 238000004519 manufacturing process Methods 0.000 description 7
- RWSOTUBLDIXVET-UHFFFAOYSA-N Dihydrogen sulfide Chemical compound S RWSOTUBLDIXVET-UHFFFAOYSA-N 0.000 description 6
- 108010024636 Glutathione Proteins 0.000 description 6
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 6
- 229960003180 glutathione Drugs 0.000 description 6
- 239000000843 powder Substances 0.000 description 6
- 229910052717 sulfur Inorganic materials 0.000 description 6
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- 125000000291 glutamic acid group Chemical group N[C@@H](CCC(O)=O)C(=O)* 0.000 description 4
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- PWKSKIMOESPYIA-BYPYZUCNSA-N L-N-acetyl-Cysteine Chemical compound CC(=O)N[C@@H](CS)C(O)=O PWKSKIMOESPYIA-BYPYZUCNSA-N 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
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- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 description 2
- GYDPOKGOQFTYGW-UHFFFAOYSA-N 3-Methyl-2-butene-1-thiol Chemical compound CC(C)=CCS GYDPOKGOQFTYGW-UHFFFAOYSA-N 0.000 description 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- UGFAIRIUMAVXCW-UHFFFAOYSA-N Carbon monoxide Chemical compound [O+]#[C-] UGFAIRIUMAVXCW-UHFFFAOYSA-N 0.000 description 2
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 description 2
- UQSXHKLRYXJYBZ-UHFFFAOYSA-N Iron oxide Chemical compound [Fe]=O UQSXHKLRYXJYBZ-UHFFFAOYSA-N 0.000 description 2
- 244000246386 Mentha pulegium Species 0.000 description 2
- 235000016257 Mentha pulegium Nutrition 0.000 description 2
- 235000004357 Mentha x piperita Nutrition 0.000 description 2
- XUYPXLNMDZIRQH-LURJTMIESA-N N-acetyl-L-methionine Chemical compound CSCC[C@@H](C(O)=O)NC(C)=O XUYPXLNMDZIRQH-LURJTMIESA-N 0.000 description 2
- 244000061176 Nicotiana tabacum Species 0.000 description 2
- IDIDJDIHTAOVLG-UHFFFAOYSA-N S-methyl-L-cysteine Natural products CSCC(N)C(O)=O IDIDJDIHTAOVLG-UHFFFAOYSA-N 0.000 description 2
- 244000299461 Theobroma cacao Species 0.000 description 2
- 229960004308 acetylcysteine Drugs 0.000 description 2
- 239000000654 additive Substances 0.000 description 2
- 239000011324 bead Substances 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 235000019658 bitter taste Nutrition 0.000 description 2
- 239000006227 byproduct Substances 0.000 description 2
- 239000002775 capsule Substances 0.000 description 2
- 229910002091 carbon monoxide Inorganic materials 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 235000019506 cigar Nutrition 0.000 description 2
- 125000000151 cysteine group Chemical group N[C@@H](CS)C(=O)* 0.000 description 2
- 238000009826 distribution Methods 0.000 description 2
- RRAFCDWBNXTKKO-UHFFFAOYSA-N eugenol Chemical compound COC1=CC(CC=C)=CC=C1O RRAFCDWBNXTKKO-UHFFFAOYSA-N 0.000 description 2
- 238000001125 extrusion Methods 0.000 description 2
- 239000000945 filler Substances 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 238000004817 gas chromatography Methods 0.000 description 2
- 230000014509 gene expression Effects 0.000 description 2
- 239000008187 granular material Substances 0.000 description 2
- 235000001050 hortel pimenta Nutrition 0.000 description 2
- 238000010348 incorporation Methods 0.000 description 2
- 229940041616 menthol Drugs 0.000 description 2
- 239000008188 pellet Substances 0.000 description 2
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- 239000002904 solvent Substances 0.000 description 2
- 238000005507 spraying Methods 0.000 description 2
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- 125000003396 thiol group Chemical group [H]S* 0.000 description 2
- 238000011282 treatment Methods 0.000 description 2
- YDBYJHTYSHBBAU-UHFFFAOYSA-N 2-amino-4-dimethylsulfoniobutanoate Chemical compound C[S+](C)CCC(N)C([O-])=O YDBYJHTYSHBBAU-UHFFFAOYSA-N 0.000 description 1
- CLUWOWRTHNNBBU-UHFFFAOYSA-N 3-methylthiopropanal Chemical compound CSCCC=O CLUWOWRTHNNBBU-UHFFFAOYSA-N 0.000 description 1
- VDSUAILXEZKWIZ-UHFFFAOYSA-N 4-methylsulfanylbutanoic acid Chemical compound CSCCCC(O)=O VDSUAILXEZKWIZ-UHFFFAOYSA-N 0.000 description 1
- 108010088751 Albumins Proteins 0.000 description 1
- 102000009027 Albumins Human genes 0.000 description 1
- 229920003043 Cellulose fiber Polymers 0.000 description 1
- NPBVQXIMTZKSBA-UHFFFAOYSA-N Chavibetol Natural products COC1=CC=C(CC=C)C=C1O NPBVQXIMTZKSBA-UHFFFAOYSA-N 0.000 description 1
- 244000223760 Cinnamomum zeylanicum Species 0.000 description 1
- 240000007154 Coffea arabica Species 0.000 description 1
- 244000004281 Eucalyptus maculata Species 0.000 description 1
- 239000005770 Eugenol Substances 0.000 description 1
- FFFHZYDWPBMWHY-UHFFFAOYSA-N HOMOCYSTEINE Chemical compound OC(=O)C(N)CCS FFFHZYDWPBMWHY-UHFFFAOYSA-N 0.000 description 1
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 description 1
- 108010058846 Ovalbumin Proteins 0.000 description 1
- UVMRYBDEERADNV-UHFFFAOYSA-N Pseudoeugenol Natural products COC1=CC(C(C)=C)=CC=C1O UVMRYBDEERADNV-UHFFFAOYSA-N 0.000 description 1
- 244000223014 Syzygium aromaticum Species 0.000 description 1
- 235000016639 Syzygium aromaticum Nutrition 0.000 description 1
- 244000269722 Thea sinensis Species 0.000 description 1
- 235000009470 Theobroma cacao Nutrition 0.000 description 1
- 244000290333 Vanilla fragrans Species 0.000 description 1
- 235000009499 Vanilla fragrans Nutrition 0.000 description 1
- 235000012036 Vanilla tahitensis Nutrition 0.000 description 1
- 244000273928 Zingiber officinale Species 0.000 description 1
- 235000006886 Zingiber officinale Nutrition 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
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- 238000012387 aerosolization Methods 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
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- 239000000428 dust Substances 0.000 description 1
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Images
Classifications
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
- A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
- A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
- A24B15/302—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances by natural substances obtained from animals or plants
- A24B15/303—Plant extracts other than tobacco
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
- A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
- A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
- A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
- A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
- A24B15/302—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances by natural substances obtained from animals or plants
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24D—CIGARS; CIGARETTES; TOBACCO SMOKE FILTERS; MOUTHPIECES FOR CIGARS OR CIGARETTES; MANUFACTURE OF TOBACCO SMOKE FILTERS OR MOUTHPIECES
- A24D1/00—Cigars; Cigarettes
- A24D1/002—Cigars; Cigarettes with additives, e.g. for flavouring
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24D—CIGARS; CIGARETTES; TOBACCO SMOKE FILTERS; MOUTHPIECES FOR CIGARS OR CIGARETTES; MANUFACTURE OF TOBACCO SMOKE FILTERS OR MOUTHPIECES
- A24D1/00—Cigars; Cigarettes
- A24D1/22—Cigarettes with integrated combustible heat sources, e.g. with carbonaceous heat sources
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
- A24F42/00—Simulated smoking devices other than electrically operated; Component parts thereof; Manufacture or testing thereof
- A24F42/10—Devices with chemical heating means
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Toxicology (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Botany (AREA)
- Manufacture Of Tobacco Products (AREA)
- Cigarettes, Filters, And Manufacturing Of Filters (AREA)
- Fats And Perfumes (AREA)
Description
式中、
R1はOHまたはアミノ酸残基であり、
R2はH、C(O)CH3、またはアミノ酸残基であり、
R3はHまたはC1−C3非置換型アルキルであり、
R4は随意で、存在する場合にはC1−C3非置換型アルキルであり、
xは1〜3の整数である。
式中、
R1はOHまたはアミノ酸残基であり、
R2はH、C(O)CH3、またはアミノ酸残基であり、
R3はH、C1−C3非置換型アルキルまたはアミノ酸残基であり、
xは1〜3の整数である。
式中、
R1はOHまたはアミノ酸残基であり、
R2はH、C(O)CH3、またはアミノ酸残基であり、
xは1〜3の整数である。
Claims (3)
- 喫煙物品(101,102)であって、
たばこを含むエアロゾル形成基体(106,111)と、
前記エアロゾル形成基体を加熱するが燃焼はしないように構成された発熱体(104,113)と、
前記エアロゾル形成基体に追加される風味前駆体化合物であって、前記風味前駆体化合物が、前記発熱体による前記エアロゾル形成基体の加熱に伴い、チオール含有風味化合物を放出するものとを含み、
前記たばこおよび前記風味前駆体化合物の加熱の結果、フルフリルチオールが生成される、喫煙物品。 - 前記風味前駆体化合物が前記風味化合物を約200℃〜約450℃の温度で放出するよう構成された、請求項1に記載の喫煙物品。
- ニコチンまたはニコチン源をさらに含む、請求項1または2に記載の喫煙物品。
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361907441P | 2013-11-22 | 2013-11-22 | |
EP13194143 | 2013-11-22 | ||
US61/907,441 | 2013-11-22 | ||
EP13194143.7 | 2013-11-22 | ||
PCT/IB2014/066172 WO2015075650A1 (en) | 2013-11-22 | 2014-11-19 | Smoking composition comprising flavour precursor |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2020006650A Division JP2020058390A (ja) | 2013-11-22 | 2020-01-20 | 風味前駆体を含む喫煙用組成物 |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2017500002A JP2017500002A (ja) | 2017-01-05 |
JP2017500002A5 JP2017500002A5 (ja) | 2017-12-21 |
JP6682430B2 true JP6682430B2 (ja) | 2020-04-15 |
Family
ID=49674189
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2016522111A Active JP6682430B2 (ja) | 2013-11-22 | 2014-11-19 | 風味前駆体を含む喫煙用組成物 |
Country Status (19)
Country | Link |
---|---|
US (2) | US20160286851A1 (ja) |
EP (1) | EP3071057B1 (ja) |
JP (1) | JP6682430B2 (ja) |
KR (1) | KR102289549B1 (ja) |
CN (1) | CN105744848B (ja) |
AU (1) | AU2014351398B2 (ja) |
BR (1) | BR112016008829B1 (ja) |
CA (1) | CA2928020A1 (ja) |
ES (1) | ES2645338T3 (ja) |
HK (1) | HK1223249A1 (ja) |
IL (1) | IL245494B (ja) |
MX (1) | MX2016006506A (ja) |
MY (1) | MY180432A (ja) |
PH (1) | PH12016500588A1 (ja) |
PL (1) | PL3071057T3 (ja) |
PT (1) | PT3071057T (ja) |
UA (1) | UA117836C2 (ja) |
WO (1) | WO2015075650A1 (ja) |
ZA (1) | ZA201602268B (ja) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2524293B (en) * | 2014-03-19 | 2017-12-06 | Kind Consumer Ltd | An inhaler |
TW201700019A (zh) * | 2015-06-30 | 2017-01-01 | 菲利浦莫里斯製品股份有限公司 | 具有改良的熄滅性的菸製品 |
GB2594423B (en) * | 2016-02-26 | 2022-03-30 | Nerudia Ltd | System, apparatus and method |
WO2018033477A1 (en) * | 2016-08-17 | 2018-02-22 | Philip Morris Products S.A. | Aerosol-generating article having improved wrapper |
JP7039562B2 (ja) * | 2016-08-17 | 2022-03-22 | フィリップ・モーリス・プロダクツ・ソシエテ・アノニム | 新型たばこ基体を有するエアロゾル発生物品 |
CA3044615A1 (en) * | 2016-12-29 | 2018-07-05 | Jt International S.A. | Tobacco mousse |
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WO2015075650A1 (en) | 2015-05-28 |
KR20160086822A (ko) | 2016-07-20 |
HK1223249A1 (zh) | 2017-07-28 |
CN105744848A (zh) | 2016-07-06 |
CA2928020A1 (en) | 2015-05-28 |
UA117836C2 (uk) | 2018-10-10 |
AU2014351398A1 (en) | 2016-04-28 |
KR102289549B1 (ko) | 2021-08-17 |
IL245494A0 (en) | 2016-06-30 |
JP2017500002A (ja) | 2017-01-05 |
ZA201602268B (en) | 2017-06-28 |
US20160286851A1 (en) | 2016-10-06 |
PH12016500588B1 (en) | 2016-06-13 |
MX2016006506A (es) | 2016-08-04 |
BR112016008829A2 (ja) | 2017-08-01 |
ES2645338T3 (es) | 2017-12-05 |
EP3071057A1 (en) | 2016-09-28 |
PH12016500588A1 (en) | 2016-06-13 |
AU2014351398B2 (en) | 2018-08-09 |
BR112016008829B1 (pt) | 2022-03-08 |
MY180432A (en) | 2020-11-28 |
PT3071057T (pt) | 2017-12-21 |
US20230284673A1 (en) | 2023-09-14 |
EP3071057B1 (en) | 2017-10-04 |
PL3071057T3 (pl) | 2018-02-28 |
IL245494B (en) | 2019-12-31 |
CN105744848B (zh) | 2018-11-16 |
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