JP6675495B2 - 脳深部刺激療法の電極の三次元画像における回転配向の決定 - Google Patents

脳深部刺激療法の電極の三次元画像における回転配向の決定 Download PDF

Info

Publication number
JP6675495B2
JP6675495B2 JP2018544352A JP2018544352A JP6675495B2 JP 6675495 B2 JP6675495 B2 JP 6675495B2 JP 2018544352 A JP2018544352 A JP 2018544352A JP 2018544352 A JP2018544352 A JP 2018544352A JP 6675495 B2 JP6675495 B2 JP 6675495B2
Authority
JP
Japan
Prior art keywords
data
image
image data
tomographic
electrode
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2018544352A
Other languages
English (en)
Japanese (ja)
Other versions
JP2019511268A5 (enExample
JP2019511268A (ja
Inventor
アハツ，シュテファン
ヴェルライン，スヴェン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Brainlab SE
Original Assignee
Brainlab SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brainlab SE filed Critical Brainlab SE
Publication of JP2019511268A publication Critical patent/JP2019511268A/ja
Publication of JP2019511268A5 publication Critical patent/JP2019511268A5/ja
Application granted granted Critical
Publication of JP6675495B2 publication Critical patent/JP6675495B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/12—Arrangements for detecting or locating foreign bodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/02—Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
    • A61B6/03—Computed tomography [CT]
    • A61B6/032—Transmission computed tomography [CT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/44—Constructional features of apparatus for radiation diagnosis
    • A61B6/4417—Constructional features of apparatus for radiation diagnosis related to combined acquisition of different diagnostic modalities
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/52—Devices using data or image processing specially adapted for radiation diagnosis
    • A61B6/5211—Devices using data or image processing specially adapted for radiation diagnosis involving processing of medical diagnostic data
    • A61B6/5229—Devices using data or image processing specially adapted for radiation diagnosis involving processing of medical diagnostic data combining image data of a patient, e.g. combining a functional image with an anatomical image
    • A61B6/5247—Devices using data or image processing specially adapted for radiation diagnosis involving processing of medical diagnostic data combining image data of a patient, e.g. combining a functional image with an anatomical image combining images from an ionising-radiation diagnostic technique and a non-ionising radiation diagnostic technique, e.g. X-ray and ultrasound
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0526—Head electrodes
    • A61N1/0529—Electrodes for brain stimulation
    • A61N1/0534—Electrodes for deep brain stimulation
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/10—Segmentation; Edge detection
    • G06T7/13—Edge detection
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/10—Segmentation; Edge detection
    • G06T7/168—Segmentation; Edge detection involving transform domain methods
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/30—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to physical therapies or activities, e.g. physiotherapy, acupressure or exercising
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H30/00—ICT specially adapted for the handling or processing of medical images
    • G16H30/40—ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
    • G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
    • G16H40/63—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/08—Accessories or related features not otherwise provided for
    • A61B2090/0807—Indication means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/36—Image-producing devices or illumination devices not otherwise provided for
    • A61B2090/364—Correlation of different images or relation of image positions in respect to the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/36—Image-producing devices or illumination devices not otherwise provided for
    • A61B90/37—Surgical systems with images on a monitor during operation
    • A61B2090/376—Surgical systems with images on a monitor during operation using X-rays, e.g. fluoroscopy
    • A61B2090/3762—Surgical systems with images on a monitor during operation using X-rays, e.g. fluoroscopy using computed tomography systems [CT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
    • A61B2090/3954—Markers, e.g. radio-opaque or breast lesions markers magnetic, e.g. NMR or MRI
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
    • A61B2090/3966—Radiopaque markers visible in an X-ray image
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/4808—Multimodal MR, e.g. MR combined with positron emission tomography [PET], MR combined with ultrasound or MR combined with computed tomography [CT]
    • G01R33/4812—MR combined with X-ray or computed tomography [CT]
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10072—Tomographic images
    • G06T2207/10081—Computed x-ray tomography [CT]
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10116—X-ray image
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10116—X-ray image
    • G06T2207/10124—Digitally reconstructed radiograph [DRR]
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30204—Marker

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medical Informatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Optics & Photonics (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Theoretical Computer Science (AREA)
  • Epidemiology (AREA)
  • Primary Health Care (AREA)
  • General Physics & Mathematics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychology (AREA)
  • Pulmonology (AREA)
  • General Business, Economics & Management (AREA)
  • Business, Economics & Management (AREA)
  • Cardiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Electrotherapy Devices (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Nuclear Medicine (AREA)
JP2018544352A 2017-01-24 2017-01-24 脳深部刺激療法の電極の三次元画像における回転配向の決定 Active JP6675495B2 (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2017/051426 WO2018137759A1 (en) 2017-01-24 2017-01-24 Determining rotational orientation of a deep brain stimulation electrode in a three-dimensional image

Publications (3)

Publication Number Publication Date
JP2019511268A JP2019511268A (ja) 2019-04-25
JP2019511268A5 JP2019511268A5 (enExample) 2020-01-09
JP6675495B2 true JP6675495B2 (ja) 2020-04-01

Family

ID=57956255

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2018544352A Active JP6675495B2 (ja) 2017-01-24 2017-01-24 脳深部刺激療法の電極の三次元画像における回転配向の決定

Country Status (5)

Country Link
US (2) US11317880B2 (enExample)
EP (1) EP3376960B1 (enExample)
JP (1) JP6675495B2 (enExample)
CN (1) CN108697402B (enExample)
WO (1) WO2018137759A1 (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3532866A1 (en) 2016-10-28 2019-09-04 PPG Industries Ohio, Inc. Coatings for increasing near-infrared detection distances
KR20210087991A (ko) 2018-11-13 2021-07-13 피피지 인더스트리즈 오하이오 인코포레이티드 은닉 패턴을 검출하는 방법
US11561329B2 (en) 2019-01-07 2023-01-24 Ppg Industries Ohio, Inc. Near infrared control coating, articles formed therefrom, and methods of making the same
CN113795866B (zh) * 2019-03-12 2025-06-27 阿瑟雷克斯股份有限公司 单视场放射影像和三维模型配准方法与系统
US10959672B2 (en) * 2019-04-25 2021-03-30 Medtronic, Inc. Identification of orientation of implanted lead
CN110742652A (zh) * 2019-09-18 2020-02-04 中国科学院西安光学精密机械研究所 一种对消化道肿瘤磁辅助超声图像的三维重建设备及方法
WO2021121631A1 (en) * 2019-12-20 2021-06-24 Brainlab Ag Correcting segmentation of medical images using a statistical analysis of historic corrections
CN111544020B (zh) * 2020-04-17 2023-08-01 北京东软医疗设备有限公司 X射线成像设备的几何校正方法及装置
CN113926078B (zh) * 2020-06-29 2025-02-21 上海微创卜算子医疗科技有限公司 植入式电极的检测方法及检测装置和计算机可读存储介质
TWI737404B (zh) * 2020-07-15 2021-08-21 臺北醫學大學 醫療影像處理系統及方法
US11238591B1 (en) 2020-07-15 2022-02-01 Taipei Medical University (Tmu) Medical image processing system and method thereof
US12121379B2 (en) 2020-08-31 2024-10-22 Medtronic, Inc. Lead orientation detection
DE102020130079A1 (de) 2020-11-13 2022-05-19 Boston Scientific Neuromodulation Corporation Verfahren und System zur Ermittlung der Rotationsorientierung einer in einem Patienten implantierten Elektrode
US12541874B2 (en) 2021-10-20 2026-02-03 Medtronic, Inc. Lead orientation determination for electrical stimulation therapy
EP4173590B1 (en) * 2021-10-26 2025-05-21 Ecential Robotics Method for registering a 3d medical image with a registration phantom
US20230355191A1 (en) * 2022-05-05 2023-11-09 GE Precision Healthcare LLC System and Method for Presentation of Anatomical Orientation of 3D Reconstruction
US12588870B2 (en) 2022-05-16 2026-03-31 Medtronic, Inc. Electrode orientation detection
WO2024002476A1 (en) 2022-06-29 2024-01-04 Brainlab Ag Determining electrode orientation using optimized imaging parameters
CN116524011B (zh) * 2023-04-26 2024-04-30 北京航空航天大学 一种居家环境下机器人对目标位姿的精化方法
CN119680098A (zh) * 2024-12-11 2025-03-25 景昱医疗科技（苏州）股份有限公司 应用于方向性刺激电极的电极朝向确定方法、装置及系统
WO2026129742A1 (zh) * 2024-12-16 2026-06-25 景昱医疗科技（苏州）股份有限公司 电极导线及识别电极片朝向的方法
CN119656468A (zh) * 2024-12-16 2025-03-21 景昱医疗科技（苏州）股份有限公司 一种方向性电极及植入式刺激系统

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005028746B4 (de) * 2005-06-21 2018-02-22 Siemens Healthcare Gmbh Verfahren zum Ermitteln der Position und Orientierung eines Objekts, insbesondere eines Katheters, aus zweidimonsionalen Röntgenbildern
US20090220136A1 (en) * 2006-02-03 2009-09-03 University Of Florida Research Foundation Image Guidance System for Deep Brain Stimulation
US7394889B2 (en) * 2006-05-18 2008-07-01 Varian Medical Systems Technologies, Inc. Contrast-enhanced cone beam X-ray imaging, evaluation, monitoring and treatment delivery
US20080147086A1 (en) * 2006-10-05 2008-06-19 Marcus Pfister Integrating 3D images into interventional procedures
CN101687097B (zh) * 2007-07-10 2014-02-26 沙皮恩斯脑部刺激控制有限公司 神经刺激系统
US9220889B2 (en) * 2008-02-11 2015-12-29 Intelect Medical, Inc. Directional electrode devices with locating features
US8849632B2 (en) * 2008-05-15 2014-09-30 Intelect Medical, Inc. Clinician programmer system and method for generating interface models and displays of volumes of activation
US8995731B2 (en) * 2008-11-26 2015-03-31 Medtronic, Inc. Image-based characterization of implanted medical leads
CN102316816B (zh) * 2009-02-12 2014-11-05 皇家飞利浦电子股份有限公司 用于确定导管取向的系统
JP5759446B2 (ja) * 2009-04-02 2015-08-05 コーニンクレッカ フィリップス エヌ ヴェ 解剖学的特徴を輪郭抽出するシステム、作動方法及びコンピュータ可読媒体
CN102147919B (zh) * 2010-02-10 2013-09-25 昆明医学院第一附属医院 一种校正术前三维图像的术中配准方法和装置
WO2011159688A2 (en) * 2010-06-14 2011-12-22 Boston Scientific Neuromodulation Corporation Programming interface for spinal cord neuromodulation
WO2012009181A2 (en) * 2010-07-16 2012-01-19 Boston Scientific Neuromodulation Corporation Systems and methods for radial steering of electrode arrays
CN103002808B (zh) * 2010-07-19 2016-06-15 皇家飞利浦电子股份有限公司 起源于3d的心脏路图绘制
DE102010027692A1 (de) * 2010-07-20 2012-01-26 Siemens Aktiengesellschaft Verfahren zur Bildüberwachung bei der Implantation eines Chochlea-Implantats und Röntgeneinrichtung
WO2013044992A1 (en) * 2011-09-30 2013-04-04 Brainlab Ag Dose distribution display method using colours
US9549707B2 (en) 2011-11-01 2017-01-24 Siemens Medical Solutions Usa, Inc. System for orientation and display of ultrasound imaging data
US20140094823A1 (en) * 2012-10-03 2014-04-03 Boston Scientific Neuromodulation Corporation Micro-electrode recording-guided implantation of directional leads
US9406130B2 (en) * 2012-10-26 2016-08-02 Brainlab Ag Determining an anatomical atlas
WO2014100397A1 (en) * 2012-12-21 2014-06-26 Jason Spencer Catheter orienting markers
US10799145B2 (en) * 2013-03-15 2020-10-13 The Cleveland Clinic Foundation Method and system to facilitate intraoperative positioning and guidance
US9875540B2 (en) * 2013-07-11 2018-01-23 Brainlab Ag Generation of a patient-specific anatomical atlas
WO2015010859A1 (en) * 2013-07-23 2015-01-29 Koninklijke Philips N.V. Registration system for registering an imaging device with a tracking device
JP2015181773A (ja) * 2014-03-25 2015-10-22 オリンパス株式会社 神経刺激用リード
US9999772B2 (en) * 2014-04-03 2018-06-19 Pacesetter, Inc. Systems and method for deep brain stimulation therapy
JP6376873B2 (ja) * 2014-07-16 2018-08-22 キヤノン株式会社 画像処理装置、画像処理方法及びプログラム
JP6457238B2 (ja) * 2014-10-24 2019-01-23 オリンパス株式会社 電気刺激カテーテル
US10265531B2 (en) * 2015-09-01 2019-04-23 Boston Scientific Neuromodulation Corporation Detection of lead orientation

Also Published As

Publication number Publication date
EP3376960A1 (en) 2018-09-26
EP3376960B1 (en) 2019-03-27
CN108697402A (zh) 2018-10-23
US20200237326A1 (en) 2020-07-30
CN108697402B (zh) 2022-05-31
US11317880B2 (en) 2022-05-03
US12070343B2 (en) 2024-08-27
JP2019511268A (ja) 2019-04-25
US20220249038A1 (en) 2022-08-11
WO2018137759A1 (en) 2018-08-02

Similar Documents

Publication Publication Date Title
US12070343B2 (en) Determining rotational orientation of a deep brain stimulation electrode in a three-dimensional image
CN110770792B (zh) 确定临床靶体积
US9875540B2 (en) Generation of a patient-specific anatomical atlas
US11669982B2 (en) Soft tissue stereo-tracking
US20250017667A1 (en) Determining a consensus plane for imaging a medical device
US20190012805A1 (en) Automatic detection of an artifact in patient image data
US20250114056A1 (en) Determining electrode orientation using optimized imaging parameters
US20250242177A1 (en) Ct-less free breathing image contour for planning radiation treatment
US20250256128A1 (en) Determining physically correct digitally reconstructed radiographs
EP3526799B1 (en) Optimizing an atlas
WO2025026523A1 (en) Self-validating elastic fusion

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20180822

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20190731

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20190807

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20191107

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20191115

A524 Written submission of copy of amendment under article 19 pct

Free format text: JAPANESE INTERMEDIATE CODE: A524

Effective date: 20191115

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20200226

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20200310

R150 Certificate of patent or registration of utility model

Ref document number: 6675495

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250