JP6670763B2 - 治療用途のための一酸化炭素放出分子ならびにその作製および使用の方法 - Google Patents

治療用途のための一酸化炭素放出分子ならびにその作製および使用の方法 Download PDF

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JP6670763B2
JP6670763B2 JP2016571722A JP2016571722A JP6670763B2 JP 6670763 B2 JP6670763 B2 JP 6670763B2 JP 2016571722 A JP2016571722 A JP 2016571722A JP 2016571722 A JP2016571722 A JP 2016571722A JP 6670763 B2 JP6670763 B2 JP 6670763B2
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heteroaryl
cycloalkyl
moiety
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JP2017528416A (ja
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ビンヘ ワン,
ビンヘ ワン,
ダンツ ワン,
ダンツ ワン,
シンユ ジ,
シンユ ジ,
アレクサンダー ドラガノフ,
アレクサンダー ドラガノフ,
チャオフェン ダイ,
チャオフェン ダイ,
クリシュナ ダメラ,
クリシュナ ダメラ,
ディディエ マーリン,
ディディエ マーリン,
エミリー べノアス,
エミリー べノアス,
ユチン ゼン,
ユチン ゼン,
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ジョージア ステイト ユニバーシティ リサーチ ファンデーション, インコーポレイテッド
ジョージア ステイト ユニバーシティ リサーチ ファンデーション, インコーポレイテッド
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
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JP2016571722A 2014-06-09 2015-06-09 治療用途のための一酸化炭素放出分子ならびにその作製および使用の方法 Active JP6670763B2 (ja)

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US201462009451P 2014-06-09 2014-06-09
US62/009,451 2014-06-09
PCT/US2015/034948 WO2015191616A1 (en) 2014-06-09 2015-06-09 Carbon monoxide-releasing molecules for therapeutic applications and methods of making and using thereof

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US (2) US10300069B2 (enExample)
EP (1) EP3151919B1 (enExample)
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KR (1) KR20170007857A (enExample)
CN (1) CN106794362B (enExample)
AU (1) AU2015274767B2 (enExample)
CA (1) CA2950007A1 (enExample)
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WO2015191616A1 (en) 2014-06-09 2015-12-17 Georgia State University Research Foundation, Inc. Carbon monoxide-releasing molecules for therapeutic applications and methods of making and using thereof
US11420994B2 (en) 2016-11-16 2022-08-23 Georgia State University Research Foundation, Inc. Carbon-monoxide-releasing molecules and therapeutic applications thereof
KR102373273B1 (ko) * 2017-04-18 2022-03-15 기초과학연구원 고분자형 젤과 이의 제조방법, 및 이를 포함하는 물품
WO2018231841A1 (en) 2017-06-12 2018-12-20 Georgia State University Research Foundation, Inc. Enzyme-triggered carbon monoxide releasing molecules
US20180369278A1 (en) * 2017-06-23 2018-12-27 The Regents Of The University Of Michigan Carbon monoxide-based therapies and implantable devices for the treatment of vascular disease
WO2019032879A1 (en) * 2017-08-09 2019-02-14 Georgia State University Research Foundation, Inc. CARBON MONOXIDE RELEASE MOLECULES DISCHARGED BY PHYSIOLOGICAL STIMULI
WO2019084323A1 (en) 2017-10-25 2019-05-02 Georgia State University Research Foundation, Inc. CHEMICAL RELEASE SYSTEM DELIVERED BY ENRICHMENT
CN109306049B (zh) * 2018-09-28 2020-12-01 中国热带农业科学院农产品加工研究所 植物油-壳聚糖基可生物降解pua及其制备方法和应用
CN113365617B (zh) * 2018-10-16 2025-12-23 乔治亚州立大学研究基金会股份有限公司 用于医学疾病治疗的一氧化碳前药
CN113559071B (zh) * 2021-08-18 2022-12-27 苏州大学 一种co靶向递送系统及其构建方法与应用
EP4275682A1 (en) * 2022-05-12 2023-11-15 Institut National De La Sante Et De La Recherche Medicale - Inserm Carbon monoxide-releasing molecule (corm) or composition thereof for use in the treatment or the prevention of an intestinal dysbiosis in a subject
CN117534840A (zh) * 2022-08-02 2024-02-09 巴迪脉通医疗科技(苏州)有限公司 一种可释放co的医用高分子及其制备方法及应用
WO2025090901A1 (en) * 2023-10-26 2025-05-01 Georgia State University Research Foundation, Inc. Ros-activated co prodrugs for cancer treatment

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US5670664A (en) * 1995-09-08 1997-09-23 University Of Maryland Biotechnology Institute Photosensitive organic compounds that release carbon monoxide upon illumination
EP2319518A1 (en) 2002-02-04 2011-05-11 ALFAMA-Investigacao e Desenvolvimento de Produtos Farmaceuticos Lda. Use of CO-releasing compounds for the manufacture of a medicament for the treatment of inflammatory diseases
US7807619B2 (en) 2004-11-01 2010-10-05 The Regents Of The University Of California Compositions and methods for modification of biomolecules
US8519122B2 (en) 2010-02-12 2013-08-27 The Regents Of The University Of California Compositions and methods for modification of biomolecules
WO2015191616A1 (en) 2014-06-09 2015-12-17 Georgia State University Research Foundation, Inc. Carbon monoxide-releasing molecules for therapeutic applications and methods of making and using thereof

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EP3151919A1 (en) 2017-04-12
CA2950007A1 (en) 2015-12-17
US10751344B2 (en) 2020-08-25
US20170128456A1 (en) 2017-05-11
WO2015191616A1 (en) 2015-12-17
KR20170007857A (ko) 2017-01-20
EP3151919A4 (en) 2018-02-21
US20190350937A1 (en) 2019-11-21
EP3151919B1 (en) 2023-08-30
AU2015274767B2 (en) 2020-04-16
AU2015274767A1 (en) 2017-01-05
US10300069B2 (en) 2019-05-28
CN106794362B (zh) 2021-07-06
CN106794362A (zh) 2017-05-31
JP2017528416A (ja) 2017-09-28

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