JP6668045B2 - ドラベ症候群を処置するための選択的5−ht受容体アゴニストおよびアンタゴニスト - Google Patents

ドラベ症候群を処置するための選択的5−ht受容体アゴニストおよびアンタゴニスト Download PDF

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JP6668045B2
JP6668045B2 JP2015221719A JP2015221719A JP6668045B2 JP 6668045 B2 JP6668045 B2 JP 6668045B2 JP 2015221719 A JP2015221719 A JP 2015221719A JP 2015221719 A JP2015221719 A JP 2015221719A JP 6668045 B2 JP6668045 B2 JP 6668045B2
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scn1lab
receptor
agonist
epilepsy
methyl
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JP2016216438A (ja
JP2016216438A5 (enExample
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ウィッテ ピーター ド
ウィッテ ピーター ド
リーヴェン ラガエ
リーヴェン ラガエ
ジョー スルブロン
ジョー スルブロン
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ゾゲニクス インターナショナル リミテッド
ゾゲニクス インターナショナル リミテッド
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Priority to US15/265,062 priority Critical patent/US20170071949A1/en
Publication of JP2016216438A publication Critical patent/JP2016216438A/ja
Priority to US15/989,812 priority patent/US20180325909A1/en
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JP2015221719A 2015-05-15 2015-11-12 ドラベ症候群を処置するための選択的5−ht受容体アゴニストおよびアンタゴニスト Expired - Fee Related JP6668045B2 (ja)

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US15/265,062 US20170071949A1 (en) 2015-09-14 2016-09-14 Combination treatment of specific forms of epilepsy
US15/989,812 US20180325909A1 (en) 2015-09-14 2018-05-25 Combination treatment of specific forms of epilepsy
US17/579,135 US20220193082A1 (en) 2015-09-14 2022-01-19 Combination treatment of specific forms of epilepsy

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US201562162544P 2015-05-15 2015-05-15
US62/162,544 2015-05-15

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JP2016216438A JP2016216438A (ja) 2016-12-22
JP2016216438A5 JP2016216438A5 (enExample) 2018-07-26
JP6668045B2 true JP6668045B2 (ja) 2020-03-18

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US9549909B2 (en) 2013-05-03 2017-01-24 The Katholieke Universiteit Leuven Method for the treatment of dravet syndrome
JP2019507111A (ja) 2015-12-22 2019-03-14 ゾゲニクス インターナショナル リミテッド 代謝抵抗性フェンフルラミン類縁体およびその使用法
KR102688278B1 (ko) 2015-12-22 2024-07-26 조게닉스 인터내셔널 리미티드 펜플루라민 조성물 및 그 제조 방법
CA3032996C (en) 2016-08-24 2025-05-06 Zogenix International Ltd Formulation for inhibiting formation of 5-ht 2b agonists and methods of using same
US20190091179A1 (en) * 2017-09-26 2019-03-28 Zogenix International Limited Congnitive function with fenfluramine
JP2021530541A (ja) * 2018-07-27 2021-11-11 ゼノン・ファーマシューティカルズ・インコーポレイテッドXenon Pharmaceuticals Inc. てんかんの治療方法
AU2019384963B2 (en) 2018-11-19 2022-05-26 Zogenix International Limited Methods of treating Rett syndrome using fenfluramine
WO2020112460A1 (en) * 2018-11-30 2020-06-04 Zogenix International Limited A method of treating refractory epilepsy syndromes using fenfluramine enantiomers
CN113897399A (zh) * 2021-08-31 2022-01-07 浙江赛微思生物科技有限公司 一种scn1lab基因敲除斑马鱼癫痫模型及其应用

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WO2009051747A1 (en) * 2007-10-15 2009-04-23 Concert Pharmaceuticals, Inc. Deuterated lorcaserin
US9549909B2 (en) * 2013-05-03 2017-01-24 The Katholieke Universiteit Leuven Method for the treatment of dravet syndrome
WO2015066344A1 (en) * 2013-11-01 2015-05-07 Arena Pharmaceuticals, Inc. 5-ht2c receptor agonists and compositions and methods of use

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