JP6662789B2 - 脳アミロイドーシスを処置及び／又は予防する投与計画 - Google Patents
脳アミロイドーシスを処置及び／又は予防する投与計画 Download PDFInfo
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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- A—HUMAN NECESSITIES
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
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- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| US14/684,967 US9675627B2 (en) | 2014-04-14 | 2015-04-13 | Dosing regimens for treating and/or preventing cerebral amyloidoses |
| PCT/US2015/025733 WO2015160796A1 (en) | 2014-04-14 | 2015-04-14 | Dosing regimens for treating and/or preventing cerebral amyloidoses |
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| JP2017511372A JP2017511372A (ja) | 2017-04-20 |
| JP2017511372A5 JP2017511372A5 (enExample) | 2019-05-09 |
| JP6662789B2 true JP6662789B2 (ja) | 2020-03-11 |
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| JP6061677B2 (ja) * | 2009-10-19 | 2017-01-18 | アミカス セラピューティックス インコーポレイテッド | 薬理シャペロンを用いてガングリオシドの活性を増大させて、アルツハイマー病を治療するための方法 |
| US9994589B2 (en) | 2015-12-14 | 2018-06-12 | Amicus Therapeutics, Inc. | Compounds and methods for the treatment of alzheimer's disease and/or cerebral amyloid angiopathy |
| US20220184185A1 (en) | 2018-07-25 | 2022-06-16 | Modernatx, Inc. | Mrna based enzyme replacement therapy combined with a pharmacological chaperone for the treatment of lysosomal storage disorders |
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| US5766846A (en) | 1992-07-10 | 1998-06-16 | Athena Neurosciences | Methods of screening for compounds which inhibit soluble β-amyloid peptide production |
| US5383851A (en) | 1992-07-24 | 1995-01-24 | Bioject Inc. | Needleless hypodermic injection device |
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| US6274597B1 (en) | 1998-06-01 | 2001-08-14 | Mount Sinai School Of Medicine Of New York University | Method of enhancing lysosomal α-Galactosidase A |
| US20050031651A1 (en) | 2002-12-24 | 2005-02-10 | Francine Gervais | Therapeutic formulations for the treatment of beta-amyloid related diseases |
| WO2004103368A1 (en) | 2003-05-22 | 2004-12-02 | The Hospital For Sick Children | Treatment of tay sachs or sandhoff diseases by enhancing hexosaminidase activity |
| MX2007015602A (es) | 2005-06-08 | 2008-02-21 | Amicus Therapeutics Inc | Tratamiento de trastornos del sistema nervioso central asociados con mutaciones en genes que codifican las enzimas lisosomicas. |
| JP2009537149A (ja) * | 2006-05-16 | 2009-10-29 | アミークス セラピューティックス インコーポレイテッド | ファブリー病に対する治療の選択を診断し、評価するためのアッセイ |
| ATE555788T1 (de) | 2006-06-23 | 2012-05-15 | Amicus Therapeutics Inc | Verfahren zur behandlung neurologischer erkrankungen mittels verstärkung der beta - glucocerebrosidaseaktivität |
| WO2008134628A2 (en) | 2007-04-26 | 2008-11-06 | Amicus Therapeutics, Inc. | Dosing regimens for the treatment of lysosomal storage diseases using pharmacological chaperones |
| WO2011011181A1 (en) | 2009-07-01 | 2011-01-27 | Amicus Therapeutics, Inc. | Pharmacological chaperones for the treatment of alzheimer's disease |
| JP6061677B2 (ja) | 2009-10-19 | 2017-01-18 | アミカス セラピューティックス インコーポレイテッド | 薬理シャペロンを用いてガングリオシドの活性を増大させて、アルツハイマー病を治療するための方法 |
| US20140219986A1 (en) * | 2011-03-11 | 2014-08-07 | Amicus Therapeutics ,Inc. | Dosing regimens for the treatment of fabry disease |
| ES2864774T3 (es) * | 2011-12-22 | 2021-10-14 | Centogene Ip Gmbh | Combinación de un compuesto que tiene la capacidad de reorganizar una enzima lisosomal y Ambroxol y/o un derivado de Ambroxol |
| EP2844279B1 (en) * | 2012-05-03 | 2020-12-09 | Amicus Therapeutics, Inc. | Dosing regimens for the treatment of pompe disease |
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2015
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- 2015-04-14 CN CN201580031471.1A patent/CN107148270A/zh active Pending
- 2015-04-14 SG SG11201610349SA patent/SG11201610349SA/en unknown
- 2015-04-14 KR KR1020167031756A patent/KR20170003576A/ko not_active Withdrawn
- 2015-04-14 CA CA2945707A patent/CA2945707A1/en not_active Abandoned
- 2015-04-14 HK HK18103256.3A patent/HK1243643A1/zh unknown
- 2015-04-14 AU AU2015247859A patent/AU2015247859B2/en not_active Ceased
- 2015-04-14 JP JP2016562965A patent/JP6662789B2/ja not_active Expired - Fee Related
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| Publication number | Publication date |
|---|---|
| AU2015247859A1 (en) | 2016-12-01 |
| CN107148270A (zh) | 2017-09-08 |
| US9675627B2 (en) | 2017-06-13 |
| AU2015247859B2 (en) | 2020-03-26 |
| JP2017511372A (ja) | 2017-04-20 |
| KR20170003576A (ko) | 2017-01-09 |
| WO2015160796A1 (en) | 2015-10-22 |
| US20160008383A1 (en) | 2016-01-14 |
| CA2945707A1 (en) | 2015-10-22 |
| US20170273996A1 (en) | 2017-09-28 |
| HK1243643A1 (zh) | 2018-07-20 |
| EP3131547A1 (en) | 2017-02-22 |
| SG11201610349SA (en) | 2017-01-27 |
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