JP6653706B2 - 血管腔サブ解像度セグメンテーション - Google Patents

血管腔サブ解像度セグメンテーション Download PDF

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JP6653706B2
JP6653706B2 JP2017536972A JP2017536972A JP6653706B2 JP 6653706 B2 JP6653706 B2 JP 6653706B2 JP 2017536972 A JP2017536972 A JP 2017536972A JP 2017536972 A JP2017536972 A JP 2017536972A JP 6653706 B2 JP6653706 B2 JP 6653706B2
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intensity
lumen
voxel
diameter
centerline
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JP2018501898A (ja
JP2018501898A5 (https=
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ピンカス フレイマン,モーデカイ
ピンカス フレイマン,モーデカイ
ラマシュ,イェヒエル
ゴシェン,リラン
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Koninklijke Philips NV
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    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/0002Inspection of images, e.g. flaw detection
    • G06T7/0012Biomedical image inspection
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/10Segmentation; Edge detection
    • G06T7/162Segmentation; Edge detection involving graph-based methods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/02Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
    • A61B6/03Computed tomography [CT]
    • A61B6/032Transmission computed tomography [CT]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/50Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications
    • A61B6/503Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications for diagnosis of the heart
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/50Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications
    • A61B6/504Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications for diagnosis of blood vessels, e.g. by angiography
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/52Devices using data or image processing specially adapted for radiation diagnosis
    • A61B6/5211Devices using data or image processing specially adapted for radiation diagnosis involving processing of medical diagnostic data
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/10Segmentation; Edge detection
    • G06T7/11Region-based segmentation
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
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    • G06T7/10Segmentation; Edge detection
    • G06T7/12Edge-based segmentation
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/60Analysis of geometric attributes
    • G06T7/62Analysis of geometric attributes of area, perimeter, diameter or volume
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/10Image acquisition modality
    • G06T2207/10072Tomographic images
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/10Image acquisition modality
    • G06T2207/10072Tomographic images
    • G06T2207/10081Computed x-ray tomography [CT]
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/10Image acquisition modality
    • G06T2207/10072Tomographic images
    • G06T2207/10088Magnetic resonance imaging [MRI]
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/10Image acquisition modality
    • G06T2207/10072Tomographic images
    • G06T2207/10104Positron emission tomography [PET]
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/10Image acquisition modality
    • G06T2207/10132Ultrasound image
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/20Special algorithmic details
    • G06T2207/20081Training; Learning
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/20Special algorithmic details
    • G06T2207/20112Image segmentation details
    • G06T2207/20168Radial search
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/30Subject of image; Context of image processing
    • G06T2207/30004Biomedical image processing
    • G06T2207/30048Heart; Cardiac
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/30Subject of image; Context of image processing
    • G06T2207/30004Biomedical image processing
    • G06T2207/30101Blood vessel; Artery; Vein; Vascular
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/30Subject of image; Context of image processing
    • G06T2207/30172Centreline of tubular or elongated structure

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  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medical Informatics (AREA)
  • Physics & Mathematics (AREA)
  • Theoretical Computer Science (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • General Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Optics & Photonics (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dentistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Quality & Reliability (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Geometry (AREA)
  • Primary Health Care (AREA)
  • Epidemiology (AREA)
  • Databases & Information Systems (AREA)
  • Data Mining & Analysis (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Image Analysis (AREA)
JP2017536972A 2015-01-16 2016-01-14 血管腔サブ解像度セグメンテーション Active JP6653706B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562104100P 2015-01-16 2015-01-16
US62/104,100 2015-01-16
PCT/IB2016/050156 WO2016113690A1 (en) 2015-01-16 2016-01-14 Vessel lumen sub-resolution segmentation

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JP2018501898A JP2018501898A (ja) 2018-01-25
JP2018501898A5 JP2018501898A5 (https=) 2020-01-09
JP6653706B2 true JP6653706B2 (ja) 2020-02-26

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US (1) US10580141B2 (https=)
EP (1) EP3245632B1 (https=)
JP (1) JP6653706B2 (https=)
CN (1) CN107111876B (https=)
WO (1) WO2016113690A1 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10210956B2 (en) 2012-10-24 2019-02-19 Cathworks Ltd. Diagnostically useful results in real time
EP3461253B1 (en) 2016-05-16 2023-08-09 Cathworks Ltd. Selection of vascular paths from images
EP4300419A3 (en) 2016-05-16 2024-04-03 Cathworks Ltd. System for vascular assessment
WO2018001099A1 (zh) * 2016-06-30 2018-01-04 上海联影医疗科技有限公司 一种血管提取方法与系统
CN110914866B (zh) * 2017-05-09 2024-04-30 哈特弗罗公司 用于在图像分析中进行解剖结构分割的系统和方法
US10885630B2 (en) * 2018-03-01 2021-01-05 Intuitive Surgical Operations, Inc Systems and methods for segmentation of anatomical structures for image-guided surgery
JP2024504407A (ja) * 2021-01-26 2024-01-31 フル-イドディーエー レスピ エン ヴェー 血管の寸法測定方法
US12315076B1 (en) 2021-09-22 2025-05-27 Cathworks Ltd. Four-dimensional motion analysis of a patient's coronary arteries and myocardial wall
JP2023059147A (ja) * 2021-10-14 2023-04-26 キヤノンメディカルシステムズ株式会社 医用画像処理装置、医用画像処理方法及び医用画像処理プログラム
IL314862A (en) 2022-02-10 2024-10-01 Cathworks Ltd System and method for machine-learning based sensor analysis and vascular tree segmentation
RS67435B1 (sr) 2022-12-22 2025-12-31 Hemolens Diagnostics Spolka Z Ograniczona Odpowiedzialnoscia Na računaru primenljiv postupak, proizvod računarskog programa i sistem za prikazivanje slike
IL326432A (en) 2023-08-09 2026-04-01 Cathworks Ltd Coronary artery assessment after PCI
IL326434A (en) 2023-08-09 2026-04-01 Cathworks Ltd User interface and signal leakage testing for vascular index measurement
JP7766752B2 (ja) * 2023-09-18 2025-11-10 オリンパスメディカルシステムズ株式会社 処置具
US12499646B1 (en) 2024-06-12 2025-12-16 Cathworks Ltd. Three-dimensional sizing tool for cardiac assessment

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2708166A1 (fr) * 1993-07-22 1995-01-27 Philips Laboratoire Electroniq Procédé de traitement d'images numérisées pour la détection automatique de sténoses.
JPH0765154A (ja) * 1993-08-31 1995-03-10 Toshiba Corp 血管像の定量解析装置及びその定量解析方法
WO1997013457A1 (en) * 1995-10-06 1997-04-17 Philips Electronics N.V. Determining a dimension from a density distribution
JP4421203B2 (ja) * 2003-03-20 2010-02-24 株式会社東芝 管腔状構造体の解析処理装置
CA2564240C (en) * 2004-04-26 2014-10-07 David F. Yankelevitz Medical imaging system for accurate measurement evaluation of changes in a target lesion
US20060079746A1 (en) * 2004-10-11 2006-04-13 Perret Florence M Apparatus and method for analysis of tissue classes along tubular structures
US7711165B2 (en) 2005-07-28 2010-05-04 Siemens Medical Solutions Usa, Inc. System and method for coronary artery segmentation of cardiac CT volumes
DE102006002259A1 (de) * 2006-01-17 2007-07-19 Siemens Ag Verfahren zur Untersuchung von Gefäßen eines Patienten auf der Grundlage von innerhalb eines Untersuchungsbereichs mit einem Tomographiegerät erfassten Bilddaten
US7990379B2 (en) 2006-10-25 2011-08-02 Siemens Aktiengesellschaft System and method for coronary segmentation and visualization
US8077939B2 (en) * 2006-11-22 2011-12-13 General Electric Company Methods and systems for enhanced plaque visualization
US8107707B2 (en) * 2006-11-30 2012-01-31 Koninklijke Philips Electronics N.V. Visualizing a vascular structure
US20090012382A1 (en) * 2007-07-02 2009-01-08 General Electric Company Method and system for detection of obstructions in vasculature
JP5523681B2 (ja) * 2007-07-05 2014-06-18 株式会社東芝 医用画像処理装置
WO2009056147A1 (en) 2007-10-31 2009-05-07 Aarhus Universitet Method for calculating pressures in a fluid stream through a tube section, especially a blood vessel with atherosclerotic plaque
US8126232B2 (en) 2008-03-05 2012-02-28 Siemens Aktiengesellschaft System and method for 3D vessel segmentation with minimal cuts
JP2010000306A (ja) * 2008-06-23 2010-01-07 Toshiba Corp 医用画像診断装置、画像処理装置、及びプログラム
US8094898B2 (en) * 2008-07-16 2012-01-10 Siemens Medical Solutions Usa, Inc. Functional image quality assessment
US8077954B2 (en) * 2008-08-04 2011-12-13 Siemens Aktiengesellschaft System and method for image processing
DE102009023504A1 (de) * 2009-06-02 2010-12-09 Siemens Aktiengesellschaft Verfahren zur Bestimmung eines Abmessungswerts und Abmessungsbestimmungseinrichtung
US12426789B2 (en) * 2009-09-23 2025-09-30 Lightlab Imaging, Inc. Blood vessel lumen morphology and minimum lumen area measurements data collection by intravascular imaging systems for stenosis or stent planning
US8675941B2 (en) * 2010-09-30 2014-03-18 Siemens Aktiengesellschaft Method for visualization of airway anatomical changes
EP2665406B1 (en) * 2011-01-20 2021-03-10 University of Iowa Research Foundation Automated determination of arteriovenous ratio in images of blood vessels
US10186056B2 (en) * 2011-03-21 2019-01-22 General Electric Company System and method for estimating vascular flow using CT imaging
US8600132B2 (en) * 2011-05-03 2013-12-03 General Electric Company Method and apparatus for motion correcting medical images
WO2013031744A1 (ja) * 2011-08-26 2013-03-07 イービーエム株式会社 血流性状診断のためのシステム、その方法及びコンピュータソフトウエアプログラム
RU2014137146A (ru) 2012-02-14 2016-04-10 Конинклейке Филипс Н.В. Повышение разрешающей способности изображения
JP6101048B2 (ja) * 2012-02-20 2017-03-22 キヤノン株式会社 画像処理装置及び画像処理方法
US9943233B2 (en) * 2012-10-24 2018-04-17 Cathworks Ltd. Automated measurement system and method for coronary artery disease scoring
US9858387B2 (en) * 2013-01-15 2018-01-02 CathWorks, LTD. Vascular flow assessment
CN104768465B (zh) 2012-11-06 2018-06-19 皇家飞利浦有限公司 血流储备分数(ffr)指标
US9351698B2 (en) * 2013-03-12 2016-05-31 Lightlab Imaging, Inc. Vascular data processing and image registration systems, methods, and apparatuses
WO2014149722A1 (en) * 2013-03-15 2014-09-25 Wake Forest University Health Sciences Vascular territory segmentation using mutual clustering information from image space and label space
US10165955B2 (en) * 2014-02-06 2019-01-01 Reuven Gladshtein Obtaining cardiovascular parameters using arterioles related transient time
US9943277B2 (en) * 2014-04-02 2018-04-17 International Business Machines Corporation Detecting coronary stenosis through spatio-temporal tracking
SG11201707951WA (en) * 2015-03-31 2017-10-30 Agency Science Tech & Res Method and apparatus for assessing blood vessel stenosis
GB201506842D0 (en) * 2015-04-22 2015-06-03 Ucl Business Plc And Schooling Steven Locally rigid vessel based registration for laparoscopic liver surgery
JP6516597B2 (ja) * 2015-07-07 2019-05-22 キヤノン株式会社 画像処理装置及び画像処理方法
JP5890055B1 (ja) * 2015-07-09 2016-03-22 株式会社アルム 血管画像処理装置、血管画像処理プログラム、および血管画像処理方法
JP6718975B2 (ja) * 2016-03-16 2020-07-08 ハートフロー, インコーポレイテッド 冠動脈において健全な管腔径を推定し狭窄を定量化するためのシステム及び方法

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Publication number Publication date
JP2018501898A (ja) 2018-01-25
EP3245632B1 (en) 2020-07-15
WO2016113690A1 (en) 2016-07-21
CN107111876B (zh) 2021-01-05
US10580141B2 (en) 2020-03-03
EP3245632A1 (en) 2017-11-22
US20180276828A1 (en) 2018-09-27
CN107111876A (zh) 2017-08-29

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