JP6630566B2 - 分析評価カートリッジのバルブシステム - Google Patents
分析評価カートリッジのバルブシステム Download PDFInfo
- Publication number
- JP6630566B2 JP6630566B2 JP2015520679A JP2015520679A JP6630566B2 JP 6630566 B2 JP6630566 B2 JP 6630566B2 JP 2015520679 A JP2015520679 A JP 2015520679A JP 2015520679 A JP2015520679 A JP 2015520679A JP 6630566 B2 JP6630566 B2 JP 6630566B2
- Authority
- JP
- Japan
- Prior art keywords
- rotor
- stator
- valve
- fluid
- cartridge
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/56—Labware specially adapted for transferring fluids
- B01L3/567—Valves, taps or stop-cocks
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Rigid containers without fluid transport within
- B01L3/5085—Rigid containers without fluid transport within for multiple samples, e.g. microtitration plates
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K11/00—Multiple-way valves, e.g. mixing valves; Pipe fittings incorporating such valves
- F16K11/02—Multiple-way valves, e.g. mixing valves; Pipe fittings incorporating such valves with all movable sealing faces moving as one unit
- F16K11/06—Multiple-way valves, e.g. mixing valves; Pipe fittings incorporating such valves with all movable sealing faces moving as one unit comprising only sliding valves, i.e. sliding closure elements
- F16K11/072—Multiple-way valves, e.g. mixing valves; Pipe fittings incorporating such valves with all movable sealing faces moving as one unit comprising only sliding valves, i.e. sliding closure elements with pivoted closure members
- F16K11/074—Multiple-way valves, e.g. mixing valves; Pipe fittings incorporating such valves with all movable sealing faces moving as one unit comprising only sliding valves, i.e. sliding closure elements with pivoted closure members with flat sealing faces
- F16K11/0743—Multiple-way valves, e.g. mixing valves; Pipe fittings incorporating such valves with all movable sealing faces moving as one unit comprising only sliding valves, i.e. sliding closure elements with pivoted closure members with flat sealing faces with both the supply and the discharge passages being on one side of the closure plates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0681—Filter
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0874—Three dimensional network
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0622—Valves, specific forms thereof distribution valves, valves having multiple inlets and/or outlets, e.g. metering valves, multi-way valves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0633—Valves, specific forms thereof with moving parts
- B01L2400/0644—Valves, specific forms thereof with moving parts rotary valves
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/2575—Volumetric liquid transfer
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Analytical Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Dispersion Chemistry (AREA)
- Multiple-Way Valves (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2019184210A JP6908671B2 (ja) | 2012-07-05 | 2019-10-07 | 分析評価カートリッジのバルブシステム |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261668226P | 2012-07-05 | 2012-07-05 | |
| US61/668,226 | 2012-07-05 | ||
| PCT/US2013/049296 WO2014008381A2 (en) | 2012-07-05 | 2013-07-03 | Assay cartridge valve system |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019184210A Division JP6908671B2 (ja) | 2012-07-05 | 2019-10-07 | 分析評価カートリッジのバルブシステム |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015523571A JP2015523571A (ja) | 2015-08-13 |
| JP2015523571A5 JP2015523571A5 (https=) | 2016-09-08 |
| JP6630566B2 true JP6630566B2 (ja) | 2020-01-15 |
Family
ID=49882606
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015520679A Active JP6630566B2 (ja) | 2012-07-05 | 2013-07-03 | 分析評価カートリッジのバルブシステム |
| JP2019184210A Active JP6908671B2 (ja) | 2012-07-05 | 2019-10-07 | 分析評価カートリッジのバルブシステム |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019184210A Active JP6908671B2 (ja) | 2012-07-05 | 2019-10-07 | 分析評価カートリッジのバルブシステム |
Country Status (4)
| Country | Link |
|---|---|
| US (4) | US10272436B2 (https=) |
| EP (1) | EP2870391B1 (https=) |
| JP (2) | JP6630566B2 (https=) |
| WO (1) | WO2014008381A2 (https=) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9638663B2 (en) | 2011-07-25 | 2017-05-02 | Proxim Diagnostics Corporation | Cartridge for diagnostic testing |
| JP6630566B2 (ja) * | 2012-07-05 | 2020-01-15 | メソ スケール テクノロジーズ エルエルシー | 分析評価カートリッジのバルブシステム |
| NL2017959B1 (en) * | 2016-12-08 | 2018-06-19 | Illumina Inc | Cartridge assembly |
| GB2516669B (en) | 2013-07-29 | 2015-09-09 | Atlas Genetics Ltd | A method for processing a liquid sample in a fluidic cartridge |
| DE102014105437A1 (de) * | 2014-04-16 | 2015-10-22 | Amodia Bioservice Gmbh | Mikrofluidik-Modul und Kassette für die immunologische und molekulare Diagnostik in einem Analyseautomaten |
| CN110038653A (zh) | 2014-05-27 | 2019-07-23 | 伊鲁米那股份有限公司 | 包括基本仪器和可拆卸盒的用于生物化学分析的系统和方法 |
| RU2688746C2 (ru) * | 2014-06-05 | 2019-05-22 | Иллумина, Инк. | Системы и способы с использованием поворотного клапана для по меньшей мере одного из приготовления образца или анализа образца |
| GB201418233D0 (en) * | 2014-10-15 | 2014-11-26 | Randox Lab Ltd | Microfluidic chip |
| US9885352B2 (en) * | 2014-11-25 | 2018-02-06 | Genia Technologies, Inc. | Selectable valve of a delivery system |
| US11123740B2 (en) | 2015-06-29 | 2021-09-21 | Arizona Board Of Regents On Behalf Of Arizona State University | Systems and methods for continuous flow digital droplet polymerase chain reaction bioanalysis |
| EA039230B1 (ru) * | 2015-07-24 | 2021-12-21 | Сифиид | Система для выполнения молекулярных диагностических анализов |
| EP3419758A1 (en) * | 2016-02-23 | 2019-01-02 | Bigtec Private Limited | A cartridge for purifying a sample and analysis |
| GB2554377A (en) * | 2016-09-23 | 2018-04-04 | Dnanudge Ltd | Method and apparatus for analysing a biological sample |
| MY194951A (en) | 2016-10-14 | 2022-12-28 | Illumina Inc | Cartridge assembly |
| WO2018091494A1 (en) * | 2016-11-17 | 2018-05-24 | F. Hoffmann-La Roche Ag | Fluid delivery system |
| WO2018098438A1 (en) | 2016-11-28 | 2018-05-31 | Arizona Board Of Regents On Behalf Of Arizona State University | Systems and methods related to continuous flow droplet reaction |
| KR102076220B1 (ko) * | 2017-12-28 | 2020-02-11 | 에스디 바이오센서 주식회사 | 핵산 추출용 카트리지의 유로 구조 |
| US10527192B2 (en) * | 2018-02-15 | 2020-01-07 | Talis Biomedical Corporation | Rotary valve |
| SG11202009478PA (en) | 2018-04-02 | 2020-10-29 | Dropworks Inc | Systems and methods for serial flow emulsion processes |
| WO2020264475A1 (en) * | 2019-06-28 | 2020-12-30 | Vanderbilt University | Microfluidic systems, pumps, valves, fluidic chips thereof, and applications of same |
| US10467679B1 (en) | 2019-04-15 | 2019-11-05 | Dnanudge Limited | Product recommendation device and method |
| AU2020232954B2 (en) | 2019-03-01 | 2026-01-15 | Meso Scale Technologies, Llc. | Electrochemiluminescent labeled probes for use in immunoassay methods, methods using such and kits comprising same |
| US10811140B2 (en) | 2019-03-19 | 2020-10-20 | Dnanudge Limited | Secure set-up of genetic related user account |
| US10699806B1 (en) | 2019-04-15 | 2020-06-30 | Dnanudge Limited | Monitoring system, wearable monitoring device and method |
| USD930184S1 (en) * | 2019-07-18 | 2021-09-07 | Spectrum Solutions L.L.C. | Sample collection device |
| USD924430S1 (en) * | 2019-07-18 | 2021-07-06 | Spectrum Solutions L.L.C. | Sample collection device |
| EP4084904A4 (en) * | 2019-12-30 | 2024-05-29 | Illumina, Inc. | FLOW CELL ARRANGEMENTS AND RELATED REAGENT SELECTION VALVES |
| WO2021222827A1 (en) | 2020-05-01 | 2021-11-04 | Meso Scale Technologies, Llc. | Methods and kits for virus detection |
| WO2021236584A1 (en) | 2020-05-19 | 2021-11-25 | Meso Scale Technologies, Llc. | Methods, compositions, and kits for nucleic acid detection |
| CN111575152B (zh) * | 2020-05-27 | 2023-09-08 | 合肥中科易康达生物医学有限公司 | 一种集成核酸提取扩增检测功能于一体的封闭式卡盒及检测方法 |
| CN113773942A (zh) * | 2020-06-10 | 2021-12-10 | 北京百康芯生物科技有限公司 | 一种核酸检测卡盒 |
| CN116194783A (zh) * | 2020-09-28 | 2023-05-30 | 积水化学工业株式会社 | 检测芯片 |
| GB2603451B (en) * | 2020-11-25 | 2024-10-02 | Oxford Nanoimaging Ltd | Reagent cartridge and measurement devices incorporating such cartridges |
| JP2024512975A (ja) | 2021-03-29 | 2024-03-21 | サンフラワー セラピューティクス,ピービーシー | 選択可能な流体カプラ |
| US20240287572A1 (en) | 2021-04-16 | 2024-08-29 | Meso Scale Technologies, Llc. | Methods, compositions, and kits for detecting hydrolase enzyme activity |
| US20220404360A1 (en) | 2021-05-21 | 2022-12-22 | Meso Scale Technologies, Llc. | Assays for viral strain determination |
| JP2024526217A (ja) | 2021-06-28 | 2024-07-17 | メソ スケール テクノロジーズ エルエルシー | アッセイシグナル増幅のための方法、組成物及びキット |
| DE102021116887A1 (de) * | 2021-06-30 | 2023-01-05 | Institut für Bioprozess- und Analysenmesstechnik e.V. | Anordnung zum Generieren von Fluidsequenzen in einem Multifluidtransportkanal zum Konditionieren und Detektieren der in dem Multifluidtransportkanal generierten Fluidsequenzen |
| EP4493940A4 (en) * | 2022-03-18 | 2026-03-18 | Illumina Inc | REAGENT CARTRIDGES AND ASSOCIATED SYSTEMS AND PROCESSES |
| WO2023245184A1 (en) | 2022-06-17 | 2023-12-21 | Meso Scale Technologies, Llc. | Viral strain serology assays |
| KR102515060B1 (ko) * | 2022-07-18 | 2023-03-29 | 한전케이피에스 주식회사 | 밸브 성능진단 시험장치 |
| US20240103002A1 (en) | 2022-09-23 | 2024-03-28 | Meso Scale Technologies, Llc. | Orthopoxvirus serology assays |
| EP4638775A1 (en) | 2022-12-20 | 2025-10-29 | Meso Scale Technologies, LLC | Assay methods and kits |
| CN115873691B (zh) * | 2023-02-24 | 2023-05-16 | 北京凡知医学科技有限公司 | 一种微流控芯片和核酸提取纯化方法及装置 |
| EP4459162A1 (en) * | 2023-05-02 | 2024-11-06 | BSH Hausgeräte GmbH | Multiway valve, water-bearing household device containing the valve and process for operating the household device |
| WO2025012428A1 (en) * | 2023-07-13 | 2025-01-16 | Curetis Gmbh | Cartridge for handling at least one substance, corresponding items and methods |
| WO2025049305A1 (en) | 2023-08-25 | 2025-03-06 | Meso Scale Technologies, Llc. | Viral strain serology assays |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61134668A (ja) | 1984-12-06 | 1986-06-21 | Toyo Soda Mfg Co Ltd | 液注入装置 |
| JP3607926B2 (ja) | 1996-10-21 | 2005-01-05 | 株式会社鷺宮製作所 | 電動多方弁 |
| JPH10120014A (ja) | 1996-10-25 | 1998-05-12 | Yoshino Kogyosho Co Ltd | 塗布容器 |
| US5819798A (en) * | 1996-11-27 | 1998-10-13 | Xerox Corporation | Multiport rotary indexing vacuum valve in a liquid ink printer |
| US6748975B2 (en) * | 2001-12-26 | 2004-06-15 | Micralyne Inc. | Microfluidic valve and method of manufacturing same |
| DE602005026500D1 (de) * | 2005-07-15 | 2011-04-07 | Agilent Technologies Inc | Vorrichtung zur Handhaben von mikrofluidischen Vorrichtungen mit einer Klemmeinrichtung |
| JP4670590B2 (ja) | 2005-10-28 | 2011-04-13 | 株式会社島津製作所 | 流路切換バルブ及びそれを用いた高速液体クロマトグラフ |
| US7377291B2 (en) * | 2005-12-28 | 2008-05-27 | Serveron Corporation | Multiport rotary valve |
| US20070194508A1 (en) * | 2006-02-21 | 2007-08-23 | Bucciero Henry R | Spring fabricated from a tube |
| US7950296B2 (en) * | 2007-06-01 | 2011-05-31 | Siemens Industry, Inc. | Continuous flow sample introduction apparatus and method |
| DE102008002674B9 (de) * | 2008-06-26 | 2010-10-21 | INSTITUT FüR MIKROTECHNIK MAINZ GMBH | Mikroventil und Abdichteinrichtung zur Verwendung in einem Mikrofluidiksystem sowie Verfahren zu deren Herstellung |
| DE102008002675B4 (de) * | 2008-06-26 | 2014-11-06 | INSTITUT FüR MIKROTECHNIK MAINZ GMBH | Abdichteinrichtung zur Verwendung in einem Probeaufbereitungschip sowie Verfahren zu deren Herstellung |
| US8480953B2 (en) | 2009-05-20 | 2013-07-09 | Protedyne Corporation | System and method for vessel alignment |
| EP4459241A3 (en) * | 2009-12-07 | 2025-01-01 | Meso Scale Technologies, LLC. | Assay cartridge reader |
| JP5800836B2 (ja) * | 2010-02-25 | 2015-10-28 | アイデックス・ヘルス・アンド・サイエンス・リミテッド ライアビリティ カンパニーIdex Health & Science Llc | マイクロ流体弁取り付け装置、マイクロ流体弁アセンブリ、及び、マイクロ流体弁システム |
| JP5824281B2 (ja) * | 2010-08-10 | 2015-11-25 | アークレイ株式会社 | 電気泳動装置、および電気泳動装置の制御方法 |
| JP2012093352A (ja) * | 2010-09-28 | 2012-05-17 | Arkray Inc | 気泡除去方法、気泡除去装置、それを用いた分析装置、気泡除去制御プログラム、およびこのプログラムの記憶媒体 |
| WO2012042226A2 (en) * | 2010-10-01 | 2012-04-05 | Oxford Nanopore Technologies Limited | Biochemical analysis apparatus and rotary valve |
| JP6630566B2 (ja) | 2012-07-05 | 2020-01-15 | メソ スケール テクノロジーズ エルエルシー | 分析評価カートリッジのバルブシステム |
-
2013
- 2013-07-03 JP JP2015520679A patent/JP6630566B2/ja active Active
- 2013-07-03 US US14/412,866 patent/US10272436B2/en active Active
- 2013-07-03 EP EP13813712.0A patent/EP2870391B1/en active Active
- 2013-07-03 WO PCT/US2013/049296 patent/WO2014008381A2/en not_active Ceased
-
2019
- 2019-03-05 US US16/292,521 patent/US11135594B2/en active Active
- 2019-10-07 JP JP2019184210A patent/JP6908671B2/ja active Active
-
2021
- 2021-10-01 US US17/492,207 patent/US12017229B2/en active Active
-
2024
- 2024-05-22 US US18/671,149 patent/US20240382969A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP6908671B2 (ja) | 2021-07-28 |
| US10272436B2 (en) | 2019-04-30 |
| JP2020020807A (ja) | 2020-02-06 |
| US20220097072A1 (en) | 2022-03-31 |
| JP2015523571A (ja) | 2015-08-13 |
| EP2870391B1 (en) | 2019-03-27 |
| US20150190810A1 (en) | 2015-07-09 |
| US11135594B2 (en) | 2021-10-05 |
| US12017229B2 (en) | 2024-06-25 |
| WO2014008381A3 (en) | 2014-02-20 |
| US20240382969A1 (en) | 2024-11-21 |
| EP2870391A4 (en) | 2016-03-09 |
| EP2870391A2 (en) | 2015-05-13 |
| WO2014008381A2 (en) | 2014-01-09 |
| US20190201906A1 (en) | 2019-07-04 |
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