JP6626847B2 - 吸入デバイス - Google Patents
吸入デバイス Download PDFInfo
- Publication number
- JP6626847B2 JP6626847B2 JP2016574383A JP2016574383A JP6626847B2 JP 6626847 B2 JP6626847 B2 JP 6626847B2 JP 2016574383 A JP2016574383 A JP 2016574383A JP 2016574383 A JP2016574383 A JP 2016574383A JP 6626847 B2 JP6626847 B2 JP 6626847B2
- Authority
- JP
- Japan
- Prior art keywords
- vibrator
- drug
- spacer
- transducer
- chamber
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0085—Inhalators using ultrasonics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/005—Sprayers or atomisers specially adapted for therapeutic purposes using ultrasonics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0005—Details of inhalators; Constructional features thereof with means for agitating the medicament
- A61M15/001—Details of inhalators; Constructional features thereof with means for agitating the medicament using ultrasonic means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/002—Details of inhalators; Constructional features thereof with air flow regulating means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B17/00—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
- B05B17/04—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
- B05B17/06—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
- B05B17/0607—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers
- B05B17/0653—Details
- B05B17/0661—Transducer materials
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B7/00—Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas
- B05B7/14—Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas designed for spraying particulate materials
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B7/00—Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas
- B05B7/14—Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas designed for spraying particulate materials
- B05B7/1404—Arrangements for supplying particulate material
- B05B7/1413—Apparatus to be carried on or by a person, e.g. by hand; Apparatus comprising a container fixed to the discharge device
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2207/00—Methods of manufacture, assembly or production
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B17/00—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
- B05B17/04—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
- B05B17/06—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
- B05B17/0607—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Special Spraying Apparatus (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Description
(1)小さいサイズの粒子は、製造および貯蔵の間に粒子自体に静電荷を発生させることがある。これにより、粒子がそれ自体もしくは肺グレードのラクトースなどの製剤添加剤に対して塊状化また凝集し、結果として、5ミクロン超の実効サイズを有する粒子の塊が生じる可能性がある。その場合、こうした大きい塊が肺の奥まで到達する確率は低くなる。このため、パッケージ化された薬物のうち、患者が吸収に利用できる割合が低くなる。
(2)患者に送達する必要がある活性薬物の量は、数十マイクログラム程度、またはそれより少ない場合がある。たとえば、喘息に使用される薬物であるアルブテロールの場合、これは通常25〜50マイクログラムである。現在の製造装置は、ミリグラムの用量範囲内の一定分量の薬物を、許容可能な精度で効果的に提供することができる。したがって、標準的な実施は、活性薬物をラクトース等の賦形剤または充填剤と混合することである。またこの添加物は、薬物を「流れやすく」する。この賦形剤は、これらの粒子に薬物粒子が静電的または化学的な結合によって固着するため、キャリアとも呼ばれる。こうしたキャリア粒子のサイズは、薬物粒子よりもずっと大きい。乾燥粉末吸入器がキャリアから薬物を分離する能力は、設計の有効性における重要な性能パラメータである。
(3)製薬業界では一般的に、5ミクロン超のサイズを有する活性薬物粒子は、口または咽頭の中に堆積すると考えられている。こうした場所における薬物の生物学的利用能および吸収は肺とは異なるため、これによって別のレベルの不確実性がもたらされる。乾燥粉末吸入器は、こうした場所に堆積する薬物を最小限に抑え、薬物の生物学的利用能に関連付けられる不確実性を低減する必要がある。
・ 先行技術の吸入器の性能は、使用者が生じさせる流量に依存する。流量が小さいと粉末が完全に分解されず、したがって患者に送達される用量に悪影響を及ぼす。
・ 分解プロセスに一貫性が欠如しているため、用量間の薬物の生物学的利用能に一貫性がない。
・ 電気機械ベースの吸入器を駆動するには大きいエネルギーが必要であるため、デバイスはサイズが大きくなり、携帯使用に不向きになる。
・ 開放されたまたは先端が切り取られたカプセルからの薬剤の損失。
・ 酸素または湿気に曝されることによる、開放されたまたは先端が切り取られたカプセル内の薬剤の劣化。
13 壁
14 圧電セラミックディスク、圧電ディスク、ディスク
15 回路基板
16 正極リード線
18 シリコーン接着剤
20 負極リード線
22 金属スペーサ、スペーサ
24 タブ
26 張力隔離碍子リング、リング
30 間隙
Claims (15)
- 薬を保持するための投薬チャンバと、前記投薬チャンバと相互作用して前記薬をエアロゾル化するためのバイブレータとを含む吸入デバイスであって、
平面視で実質的に円形であり、前記バイブレータの面の外周のまわりに配置された、バイブレータの前記面と前記投薬チャンバの壁との間のスペーサであって、前記バイブレータの前記面と前記投薬チャンバの前記壁との間に空気隙間が作られるようなスペーサを含むデバイス。 - 前記バイブレータは圧電トランスデューサ組立体を含む、請求項1に記載のデバイス。
- 前記バイブレータの前記面の上に隔離碍子のスリーブをさらに含む、請求項1又は請求項2に記載のデバイス。
- 前記隔離碍子のスリーブは二軸延伸ポリマー材料で形成される、請求項3に記載のデバイス。
- 前記スペーサは金属で作られる、請求項1〜4のいずれか一項に記載のデバイス。
- 前記薬は液体を含む、請求項1〜5のいずれか一項に記載のデバイス。
- 前記薬は乾燥粉末を含む、請求項1〜6のいずれか一項に記載のデバイス。
- 前記スペーサは1つまたは複数の間隙によって分割される、請求項1〜7のいずれか一項に記載のデバイス。
- 薬を保持するための投薬チャンバを有する吸入器デバイス内にバイブレータを配置するための方法であって、
平面視で実質的に円形であり、前記バイブレータの面の外周のまわりに配置された、前記バイブレータの前記面と前記投薬チャンバの壁との間にスペーサを位置決めするステップであって、前記バイブレータの前記面と前記投薬チャンバの前記壁との間に空気隙間が作られる、ステップ
を含む方法。 - バイブレータは圧電トランスデューサを含む、請求項9に記載の方法。
- 前記バイブレータの面端部の上に隔離碍子のスリーブを加えるステップをさらに含む、請求項9又は請求項10に記載の方法。
- 前記隔離碍子のスリーブはポリマー材料で形成される、請求項11に記載の方法。
- 前記スペーサは金属で作られる、請求項9〜12のいずれか一項に記載の方法。
- 前記薬は液体を含む、請求項9〜13のいずれか一項に記載の方法。
- 前記薬は乾燥粉末を含む、請求項9〜13のいずれか一項に記載の方法。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462021560P | 2014-07-07 | 2014-07-07 | |
US62/021,560 | 2014-07-07 | ||
PCT/US2015/038882 WO2016007356A1 (en) | 2014-07-07 | 2015-07-01 | Inhalation device |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2017522101A JP2017522101A (ja) | 2017-08-10 |
JP6626847B2 true JP6626847B2 (ja) | 2019-12-25 |
Family
ID=53546756
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2016574383A Expired - Fee Related JP6626847B2 (ja) | 2014-07-07 | 2015-07-01 | 吸入デバイス |
Country Status (19)
Country | Link |
---|---|
US (1) | US10744278B2 (ja) |
EP (2) | EP3166666B1 (ja) |
JP (1) | JP6626847B2 (ja) |
KR (2) | KR102235192B1 (ja) |
CN (1) | CN106573120B (ja) |
AR (1) | AR105409A1 (ja) |
AU (1) | AU2015288166B2 (ja) |
BR (1) | BR112017000356A2 (ja) |
CA (1) | CA2951966C (ja) |
CL (1) | CL2017000044A1 (ja) |
EA (1) | EA032922B1 (ja) |
ES (1) | ES2860998T3 (ja) |
IL (1) | IL249015A0 (ja) |
MX (1) | MX2017000287A (ja) |
PE (1) | PE20161503A1 (ja) |
TW (1) | TWI595898B (ja) |
UA (1) | UA121480C2 (ja) |
WO (1) | WO2016007356A1 (ja) |
ZA (1) | ZA201608603B (ja) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA3039908A1 (en) * | 2016-10-11 | 2018-04-19 | Microdose Therapeutx, Inc. | Inhaler and methods of use thereof |
WO2018071435A1 (en) | 2016-10-11 | 2018-04-19 | Microdose Therapeutx, Inc. | Inhaler and methods of use thereof |
WO2020102464A1 (en) | 2018-11-15 | 2020-05-22 | Xtreme Prototyping, Inc. | Compact ultrasonic atomizers using folded resonators |
Family Cites Families (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2517482A (en) | 1949-04-09 | 1950-08-01 | Sharp & Dohme Inc | Inhaler |
US3507277A (en) | 1966-09-17 | 1970-04-21 | Fisons Pharmaceuticals Ltd | Inhalation device |
GB1182779A (en) | 1966-09-17 | 1970-03-04 | Fisons Pharmaceuticals Ltd | Inhalation Device |
GB1268051A (en) | 1968-06-07 | 1972-03-22 | Fisons Pharmaceuticals Ltd | Inhalation device |
US3831606A (en) | 1971-02-19 | 1974-08-27 | Alza Corp | Auto inhaler |
IT941426B (it) | 1971-07-17 | 1973-03-01 | Isf Spa | Inalatore a camera di turbinio per sostanze medicamentose polveriformi |
US3795244A (en) | 1973-02-02 | 1974-03-05 | Syntex Corp | Inhalation device |
US3948264A (en) | 1975-05-21 | 1976-04-06 | Mead Johnson & Company | Inhalation device |
US4976259A (en) * | 1986-12-22 | 1990-12-11 | Mountain Medical Equipment, Inc. | Ultrasonic nebulizer |
DE69233690T2 (de) | 1991-07-02 | 2008-01-24 | Nektar Therapeutics, San Carlos | Abgabevorrichtung für nebelförmige Medikamente |
US6026809A (en) | 1996-01-25 | 2000-02-22 | Microdose Technologies, Inc. | Inhalation device |
US5694920A (en) | 1996-01-25 | 1997-12-09 | Abrams; Andrew L. | Inhalation device |
US5823434A (en) * | 1997-05-05 | 1998-10-20 | The United States Of America As Represented By The Secretary Of The Navy | Electromechanical driver for an aerosol dispensing apparatus which dispenses a medicated vapor into the lungs of a patient |
US6152130A (en) | 1998-06-12 | 2000-11-28 | Microdose Technologies, Inc. | Inhalation device with acoustic control |
US6142146A (en) | 1998-06-12 | 2000-11-07 | Microdose Technologies, Inc. | Inhalation device |
US6328033B1 (en) * | 1999-06-04 | 2001-12-11 | Zohar Avrahami | Powder inhaler |
US6283118B1 (en) * | 1999-10-13 | 2001-09-04 | Hsueh-Yu Lu | Ultrasonic nebulizer |
SE9904706D0 (sv) * | 1999-12-21 | 1999-12-21 | Astra Ab | An inhalation device |
US7080644B2 (en) | 2000-06-28 | 2006-07-25 | Microdose Technologies, Inc. | Packaging and delivery of pharmaceuticals and drugs |
CN100589849C (zh) | 2004-02-24 | 2010-02-17 | 微计量技术有限公司 | 基于合成射流的药物输送方法和装置 |
NZ549588A (en) | 2004-02-24 | 2009-03-31 | Microdose Technologies Inc | Directional flow sensor inhaler |
NZ566670A (en) * | 2005-09-06 | 2011-06-30 | Intelligent Medical Technologies Pty Ltd | Nebuliser with focal point above surface of nebulisable liquid |
GB0605676D0 (en) | 2006-03-22 | 2006-05-03 | Vectura Ltd | Improvements in extraction of powder formulations |
ES2360634T3 (es) * | 2006-04-05 | 2011-06-07 | Microdose Therapeutx, Inc. | Dispositivo de inhalación de dosis variables. |
US7779831B1 (en) * | 2006-04-20 | 2010-08-24 | Ric Investments, Llc | Ultrasonic nebulizer with metal coated ultrasonic generator |
US8196576B2 (en) | 2007-02-28 | 2012-06-12 | Microdose Therapeutx, Inc. | Inhaler |
US8439033B2 (en) | 2007-10-09 | 2013-05-14 | Microdose Therapeutx, Inc. | Inhalation device |
US8371294B2 (en) | 2008-02-29 | 2013-02-12 | Microdose Therapeutx, Inc. | Method and apparatus for driving a transducer of an inhalation device |
US20110000481A1 (en) | 2009-07-01 | 2011-01-06 | Anand Gumaste | Nebulizer for infants and respiratory compromised patients |
JP2011072398A (ja) | 2009-09-29 | 2011-04-14 | Terumo Corp | ネブライザー |
CN105381524A (zh) | 2010-01-05 | 2016-03-09 | 微剂量治疗技术公司 | 吸入设备和方法 |
US9050424B2 (en) * | 2010-01-11 | 2015-06-09 | Koninklijke Philips N.V. | Magnetic coupling for aerosol generating apparatus |
WO2011083380A1 (en) * | 2010-01-11 | 2011-07-14 | Koninklijke Philips Electronics N.V. | Magnetic coupling for aerosol generating apparatus |
US20110020252A1 (en) | 2010-10-01 | 2011-01-27 | Shantha Totada R | Method of long lasting human skin tanning |
-
2015
- 2015-07-01 ES ES15738226T patent/ES2860998T3/es active Active
- 2015-07-01 PE PE2016002503A patent/PE20161503A1/es not_active Application Discontinuation
- 2015-07-01 MX MX2017000287A patent/MX2017000287A/es unknown
- 2015-07-01 UA UAA201701042A patent/UA121480C2/uk unknown
- 2015-07-01 EP EP15738226.8A patent/EP3166666B1/en active Active
- 2015-07-01 BR BR112017000356-2A patent/BR112017000356A2/pt not_active Application Discontinuation
- 2015-07-01 JP JP2016574383A patent/JP6626847B2/ja not_active Expired - Fee Related
- 2015-07-01 WO PCT/US2015/038882 patent/WO2016007356A1/en active Application Filing
- 2015-07-01 AU AU2015288166A patent/AU2015288166B2/en not_active Ceased
- 2015-07-01 CN CN201580033300.2A patent/CN106573120B/zh not_active Expired - Fee Related
- 2015-07-01 US US15/324,478 patent/US10744278B2/en active Active
- 2015-07-01 KR KR1020177003313A patent/KR102235192B1/ko active IP Right Grant
- 2015-07-01 CA CA2951966A patent/CA2951966C/en not_active Expired - Fee Related
- 2015-07-01 EA EA201692173A patent/EA032922B1/ru not_active IP Right Cessation
- 2015-07-01 EP EP20211358.5A patent/EP3804794A1/en not_active Withdrawn
- 2015-07-01 KR KR1020217007125A patent/KR20210030496A/ko active Application Filing
- 2015-07-03 AR ARP150102152A patent/AR105409A1/es unknown
- 2015-07-07 TW TW104122064A patent/TWI595898B/zh not_active IP Right Cessation
-
2016
- 2016-11-16 IL IL249015A patent/IL249015A0/en active IP Right Grant
- 2016-12-13 ZA ZA2016/08603A patent/ZA201608603B/en unknown
-
2017
- 2017-01-06 CL CL2017000044A patent/CL2017000044A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
US20170197041A1 (en) | 2017-07-13 |
CL2017000044A1 (es) | 2017-08-04 |
EA201692173A1 (ru) | 2017-02-28 |
MX2017000287A (es) | 2017-04-27 |
PE20161503A1 (es) | 2017-01-27 |
ES2860998T3 (es) | 2021-10-05 |
CA2951966A1 (en) | 2016-01-14 |
CA2951966C (en) | 2021-03-16 |
EP3804794A1 (en) | 2021-04-14 |
TW201617103A (zh) | 2016-05-16 |
BR112017000356A2 (pt) | 2018-06-26 |
US10744278B2 (en) | 2020-08-18 |
AR105409A1 (es) | 2017-10-04 |
CN106573120B (zh) | 2020-02-07 |
CN106573120A (zh) | 2017-04-19 |
KR20210030496A (ko) | 2021-03-17 |
TWI595898B (zh) | 2017-08-21 |
AU2015288166B2 (en) | 2019-09-12 |
JP2017522101A (ja) | 2017-08-10 |
WO2016007356A1 (en) | 2016-01-14 |
KR20170028420A (ko) | 2017-03-13 |
EA032922B1 (ru) | 2019-08-30 |
AU2015288166A1 (en) | 2017-01-12 |
EP3166666A1 (en) | 2017-05-17 |
EP3166666B1 (en) | 2021-01-13 |
ZA201608603B (en) | 2018-05-30 |
UA121480C2 (uk) | 2020-06-10 |
IL249015A0 (en) | 2017-01-31 |
KR102235192B1 (ko) | 2021-04-05 |
AU2015288166A2 (en) | 2017-01-19 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP1166812B1 (en) | Packaging and delivery of pharmaceuticals and drugs | |
US20050172962A1 (en) | Blister pack for use with an inhalation device | |
US8371294B2 (en) | Method and apparatus for driving a transducer of an inhalation device | |
JP6626847B2 (ja) | 吸入デバイス | |
WO2016014153A1 (en) | Dry powder nebulizer | |
NZ584010A (en) | Pleated tape holding medicament in side-by-side pockets for inhaler |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20170111 |
|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20180629 |
|
A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20190422 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20190603 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20190814 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20191105 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20191202 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 6626847 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
LAPS | Cancellation because of no payment of annual fees |