JP6619367B2 - 検体濃度測定 - Google Patents
検体濃度測定 Download PDFInfo
- Publication number
- JP6619367B2 JP6619367B2 JP2016573879A JP2016573879A JP6619367B2 JP 6619367 B2 JP6619367 B2 JP 6619367B2 JP 2016573879 A JP2016573879 A JP 2016573879A JP 2016573879 A JP2016573879 A JP 2016573879A JP 6619367 B2 JP6619367 B2 JP 6619367B2
- Authority
- JP
- Japan
- Prior art keywords
- potential
- pulse
- cycle
- working electrode
- oxidation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000005259 measurement Methods 0.000 title claims description 30
- 238000006479 redox reaction Methods 0.000 claims description 33
- 238000012360 testing method Methods 0.000 claims description 33
- 238000009825 accumulation Methods 0.000 claims description 29
- 238000006722 reduction reaction Methods 0.000 claims description 28
- 230000003647 oxidation Effects 0.000 claims description 26
- 238000007254 oxidation reaction Methods 0.000 claims description 26
- 230000009467 reduction Effects 0.000 claims description 24
- 238000000034 method Methods 0.000 claims description 22
- 239000012491 analyte Substances 0.000 claims description 20
- 239000008364 bulk solution Substances 0.000 claims description 14
- 238000009792 diffusion process Methods 0.000 claims description 14
- 230000000694 effects Effects 0.000 claims description 10
- 230000003247 decreasing effect Effects 0.000 claims description 9
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 19
- 239000008103 glucose Substances 0.000 description 19
- 238000006243 chemical reaction Methods 0.000 description 16
- 230000035945 sensitivity Effects 0.000 description 14
- 210000004369 blood Anatomy 0.000 description 7
- 239000008280 blood Substances 0.000 description 7
- 230000000116 mitigating effect Effects 0.000 description 7
- 230000007423 decrease Effects 0.000 description 6
- 238000013459 approach Methods 0.000 description 4
- 210000004027 cell Anatomy 0.000 description 3
- 239000003153 chemical reaction reagent Substances 0.000 description 3
- 230000001419 dependent effect Effects 0.000 description 3
- 102000004190 Enzymes Human genes 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 239000013543 active substance Substances 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 238000000840 electrochemical analysis Methods 0.000 description 1
- 210000003743 erythrocyte Anatomy 0.000 description 1
- 238000005534 hematocrit Methods 0.000 description 1
- 230000036571 hydration Effects 0.000 description 1
- 238000006703 hydration reaction Methods 0.000 description 1
- 238000009533 lab test Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 239000000376 reactant Substances 0.000 description 1
- 238000011946 reduction process Methods 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
- G01N27/3274—Corrective measures, e.g. error detection, compensation for temperature or hematocrit, calibration
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Electrochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1412156.0A GB201412156D0 (en) | 2014-07-08 | 2014-07-08 | Analyte concentration measurement |
| GB1412156.0 | 2014-07-08 | ||
| PCT/GB2015/051973 WO2016005743A1 (en) | 2014-07-08 | 2015-07-08 | Analyte concentration measurement |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017519990A JP2017519990A (ja) | 2017-07-20 |
| JP6619367B2 true JP6619367B2 (ja) | 2019-12-11 |
Family
ID=51410820
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016573879A Expired - Fee Related JP6619367B2 (ja) | 2014-07-08 | 2015-07-08 | 検体濃度測定 |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP3167282A1 (ru) |
| JP (1) | JP6619367B2 (ru) |
| KR (1) | KR20170028408A (ru) |
| CN (1) | CN106687803A (ru) |
| AU (1) | AU2015287447A1 (ru) |
| BR (1) | BR112017000305A2 (ru) |
| CA (1) | CA2953452A1 (ru) |
| GB (1) | GB201412156D0 (ru) |
| RU (1) | RU2680266C2 (ru) |
| WO (1) | WO2016005743A1 (ru) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108350408B (zh) | 2015-08-25 | 2022-12-16 | 阿威尔斯医疗公司 | 用于检测流体样品中有活力的微生物的设备、系统和方法 |
| EP4397973A2 (en) | 2016-05-31 | 2024-07-10 | Avails Medical, Inc. | Devices, systems and methods to detect viable infectious agents in a fluid sample and susceptibility of infectious agents to anti-infectives |
| US20180306744A1 (en) * | 2017-04-20 | 2018-10-25 | Lifescan Scotland Limited | Analyte measurement system and method |
| WO2019005296A1 (en) | 2017-06-27 | 2019-01-03 | Avails Medical, Inc. | APPARATUS, SYSTEMS AND METHODS FOR DETERMINING THE SENSITIVITY OF MICROORGANISMS TO ANTI-INFECTIOUS |
| CN111182971B (zh) * | 2017-10-03 | 2022-08-30 | 阿威尔斯医疗公司 | 用于基于氧化还原反应测定微生物的浓度和微生物对抗感染剂的敏感性的装置、系统和方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7455975B2 (en) * | 2000-04-14 | 2008-11-25 | Esa Biosciences, Inc. | Electrochemical detection of nucleic acid sequences |
| RU2267120C2 (ru) * | 2000-07-14 | 2005-12-27 | Лайфскен, Инк. | Электрохимический способ измерения скоростей химических реакций |
| GB0211449D0 (en) * | 2002-05-17 | 2002-06-26 | Oxford Biosensors Ltd | Analyte measurement |
| WO2005073708A2 (de) * | 2004-01-29 | 2005-08-11 | Siemens Aktiengesellschaft | Verfahren zur messung der konzentration oder konzentrationsänderung einer redoxaktiven substanz und zugehörige vorrichtung |
| CN1981192B (zh) * | 2004-05-14 | 2014-04-16 | 拜尔健康护理有限责任公司 | 检测生物分析物的伏安测量系统 |
| US7749371B2 (en) * | 2005-09-30 | 2010-07-06 | Lifescan, Inc. | Method and apparatus for rapid electrochemical analysis |
| ES2397663T3 (es) * | 2006-10-05 | 2013-03-08 | Lifescan Scotland Limited | Sistemas y procedimientos para determinar una concentración de un analito sustancialmente independiente del hematocrito |
| US8603768B2 (en) * | 2008-01-17 | 2013-12-10 | Lifescan, Inc. | System and method for measuring an analyte in a sample |
| WO2012012341A1 (en) * | 2010-07-19 | 2012-01-26 | Cilag Gmbh International | System and method for measuring an analyte in a sample |
| US9201038B2 (en) * | 2012-07-24 | 2015-12-01 | Lifescan Scotland Limited | System and methods to account for interferents in a glucose biosensor |
| US9005426B2 (en) * | 2012-09-28 | 2015-04-14 | Cilag Gmbh International | System and method for determining hematocrit insensitive glucose concentration |
| GB2515299B (en) * | 2013-06-18 | 2015-12-30 | Suresensors Ltd | Methods and apparatus for determining analyte in a sample |
-
2014
- 2014-07-08 GB GBGB1412156.0A patent/GB201412156D0/en not_active Ceased
-
2015
- 2015-07-08 CA CA2953452A patent/CA2953452A1/en not_active Abandoned
- 2015-07-08 JP JP2016573879A patent/JP6619367B2/ja not_active Expired - Fee Related
- 2015-07-08 BR BR112017000305A patent/BR112017000305A2/pt not_active Application Discontinuation
- 2015-07-08 KR KR1020177003207A patent/KR20170028408A/ko unknown
- 2015-07-08 WO PCT/GB2015/051973 patent/WO2016005743A1/en active Application Filing
- 2015-07-08 RU RU2017103730A patent/RU2680266C2/ru not_active IP Right Cessation
- 2015-07-08 EP EP15747510.4A patent/EP3167282A1/en not_active Withdrawn
- 2015-07-08 CN CN201580037065.6A patent/CN106687803A/zh active Pending
- 2015-07-08 AU AU2015287447A patent/AU2015287447A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| KR20170028408A (ko) | 2017-03-13 |
| AU2015287447A1 (en) | 2016-12-22 |
| JP2017519990A (ja) | 2017-07-20 |
| RU2017103730A (ru) | 2018-08-08 |
| GB201412156D0 (en) | 2014-08-20 |
| WO2016005743A1 (en) | 2016-01-14 |
| RU2680266C2 (ru) | 2019-02-19 |
| CA2953452A1 (en) | 2016-01-14 |
| EP3167282A1 (en) | 2017-05-17 |
| RU2017103730A3 (ru) | 2019-01-14 |
| BR112017000305A2 (pt) | 2017-10-31 |
| CN106687803A (zh) | 2017-05-17 |
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