JP6559568B2 - ウェルからの拘束液体の抽出 - Google Patents
ウェルからの拘束液体の抽出 Download PDFInfo
- Publication number
- JP6559568B2 JP6559568B2 JP2015541936A JP2015541936A JP6559568B2 JP 6559568 B2 JP6559568 B2 JP 6559568B2 JP 2015541936 A JP2015541936 A JP 2015541936A JP 2015541936 A JP2015541936 A JP 2015541936A JP 6559568 B2 JP6559568 B2 JP 6559568B2
- Authority
- JP
- Japan
- Prior art keywords
- extraction
- extraction device
- chip
- liquid
- open wells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5025—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures for parallel transport of multiple samples
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
- B01L3/50857—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates using arrays or bundles of open capillaries for holding samples
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F17—STORING OR DISTRIBUTING GASES OR LIQUIDS
- F17D—PIPE-LINE SYSTEMS; PIPE-LINES
- F17D1/00—Pipe-line systems
- F17D1/08—Pipe-line systems for liquids or viscous products
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0609—Holders integrated in container to position an object
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0819—Microarrays; Biochips
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0893—Geometry, shape and general structure having a very large number of wells, microfabricated wells
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0896—Nanoscaled
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/12—Specific details about materials
- B01L2300/126—Paper
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
- B01L2400/049—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics vacuum
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/0318—Processes
- Y10T137/0391—Affecting flow by the addition of material or energy
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/8593—Systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/2575—Volumetric liquid transfer
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Organic Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Public Health (AREA)
- Water Supply & Treatment (AREA)
- Mechanical Engineering (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- General Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Extraction Or Liquid Replacement (AREA)
- Devices For Use In Laboratory Experiments (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261724118P | 2012-11-08 | 2012-11-08 | |
| US61/724,118 | 2012-11-08 | ||
| US201361777459P | 2013-03-12 | 2013-03-12 | |
| US61/777,459 | 2013-03-12 | ||
| PCT/US2013/069214 WO2014074863A2 (en) | 2012-11-08 | 2013-11-08 | Extraction of restrained liquid from wells |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016508025A JP2016508025A (ja) | 2016-03-17 |
| JP2016508025A5 JP2016508025A5 (enExample) | 2016-12-28 |
| JP6559568B2 true JP6559568B2 (ja) | 2019-08-14 |
Family
ID=50680498
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015541936A Active JP6559568B2 (ja) | 2012-11-08 | 2013-11-08 | ウェルからの拘束液体の抽出 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US9447925B2 (enExample) |
| EP (1) | EP2916953B1 (enExample) |
| JP (1) | JP6559568B2 (enExample) |
| CN (1) | CN104884168B (enExample) |
| AU (1) | AU2013342218A1 (enExample) |
| CA (1) | CA2891088C (enExample) |
| HK (1) | HK1214200A1 (enExample) |
| WO (1) | WO2014074863A2 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7622296B2 (en) | 2004-05-28 | 2009-11-24 | Wafergen, Inc. | Apparatus and method for multiplex analysis |
| AU2013342218A1 (en) | 2012-11-08 | 2015-06-04 | Wafergen, Inc. | Extraction of restrained liquid from wells |
| WO2016134342A1 (en) | 2015-02-20 | 2016-08-25 | Wafergen, Inc. | Method for rapid accurate dispensing, visualization and analysis of single cells |
| CN108449933A (zh) * | 2015-11-18 | 2018-08-24 | 宝生物工程(美国)有限公司 | 用于汇集来自多孔装置的样品的系统和方法 |
| CN109070044B (zh) | 2016-07-21 | 2021-07-30 | 宝生物工程(美国)有限公司 | 使用多孔装置进行的多z平面成像和分配 |
| CN113832219A (zh) * | 2020-06-23 | 2021-12-24 | 安徽微分基因科技有限公司 | 一种基于parms技术的纳升级超高通量snp基因分型方法 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4902481A (en) * | 1987-12-11 | 1990-02-20 | Millipore Corporation | Multi-well filtration test apparatus |
| US6083761A (en) | 1996-12-02 | 2000-07-04 | Glaxo Wellcome Inc. | Method and apparatus for transferring and combining reagents |
| US6143496A (en) * | 1997-04-17 | 2000-11-07 | Cytonix Corporation | Method of sampling, amplifying and quantifying segment of nucleic acid, polymerase chain reaction assembly having nanoliter-sized sample chambers, and method of filling assembly |
| US6893877B2 (en) | 1998-01-12 | 2005-05-17 | Massachusetts Institute Of Technology | Methods for screening substances in a microwell array |
| US6274088B1 (en) | 1998-04-06 | 2001-08-14 | Pharmacopeia, Inc. | Methods and apparatus for high throughput plate to plate or plate to membrane transfer |
| DE10026647A1 (de) * | 2000-05-29 | 2001-12-06 | Merck Patent Gmbh | Positioniervorrichtung |
| CA2311622A1 (en) * | 2000-06-15 | 2001-12-15 | Moussa Hoummady | Sub-nanoliter liquid drop dispensing system and method therefor |
| WO2003028878A1 (en) | 2001-09-28 | 2003-04-10 | Dynametrix Limited | Methods and means for creating arrays |
| US6994544B2 (en) * | 2004-01-30 | 2006-02-07 | Texas Instruments Incorporated | Wafer scale thermal stress fixture and method |
| US7622296B2 (en) | 2004-05-28 | 2009-11-24 | Wafergen, Inc. | Apparatus and method for multiplex analysis |
| US8133456B2 (en) * | 2005-11-07 | 2012-03-13 | Konica Minolta Medical & Graphic, Inc. | Microreactor and method of liquid feeding making use of the same |
| WO2007098184A2 (en) * | 2006-02-21 | 2007-08-30 | Nanogen, Inc. | Methods and compositions for analyte detection |
| GB0617035D0 (en) * | 2006-08-30 | 2006-10-11 | Inverness Medical Switzerland | Fluidic indicator device |
| KR20100019409A (ko) | 2007-01-22 | 2010-02-18 | 웨이퍼젠, 인크. | 고효율 화학 반응을 위한 장치 및 방법 |
| EP2237886A1 (en) * | 2007-12-17 | 2010-10-13 | Gong, Hai-Qing | Microfluidic device |
| US20090260458A1 (en) | 2008-04-17 | 2009-10-22 | Victor Joseph | High throughput dispenser |
| JP2011062119A (ja) | 2009-09-16 | 2011-03-31 | Seiko Epson Corp | 生体試料定量用チップ |
| TW201234011A (en) * | 2010-11-01 | 2012-08-16 | Nanoink Inc | High-throughput slide processing apparatus |
| AU2013342218A1 (en) | 2012-11-08 | 2015-06-04 | Wafergen, Inc. | Extraction of restrained liquid from wells |
| WO2015116591A1 (en) * | 2014-01-30 | 2015-08-06 | Illumina, Inc. | Compositions and methods for dispensing reagents |
-
2013
- 2013-11-08 AU AU2013342218A patent/AU2013342218A1/en not_active Abandoned
- 2013-11-08 WO PCT/US2013/069214 patent/WO2014074863A2/en not_active Ceased
- 2013-11-08 JP JP2015541936A patent/JP6559568B2/ja active Active
- 2013-11-08 EP EP13852704.9A patent/EP2916953B1/en active Active
- 2013-11-08 HK HK16102432.4A patent/HK1214200A1/zh unknown
- 2013-11-08 US US14/075,631 patent/US9447925B2/en active Active
- 2013-11-08 CA CA2891088A patent/CA2891088C/en active Active
- 2013-11-08 CN CN201380058480.0A patent/CN104884168B/zh active Active
-
2016
- 2016-09-19 US US15/269,258 patent/US10500585B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2916953A2 (en) | 2015-09-16 |
| EP2916953A4 (en) | 2016-06-29 |
| CA2891088C (en) | 2024-01-02 |
| US9447925B2 (en) | 2016-09-20 |
| CN104884168B (zh) | 2017-07-18 |
| AU2013342218A1 (en) | 2015-06-04 |
| US10500585B2 (en) | 2019-12-10 |
| JP2016508025A (ja) | 2016-03-17 |
| US20140130885A1 (en) | 2014-05-15 |
| CA2891088A1 (en) | 2014-05-15 |
| WO2014074863A3 (en) | 2014-07-17 |
| WO2014074863A2 (en) | 2014-05-15 |
| EP2916953B1 (en) | 2023-03-29 |
| HK1214200A1 (zh) | 2016-07-22 |
| US20170001193A1 (en) | 2017-01-05 |
| CN104884168A (zh) | 2015-09-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP6559568B2 (ja) | ウェルからの拘束液体の抽出 | |
| US7347976B2 (en) | Methods and devices for removal of organic molecules from biological mixtures using a hydrophilic solid support in a hydrophobic matrix | |
| CN103946392B (zh) | 生化分析的系统、设备和方法 | |
| WO2005028629A2 (en) | Whole genome expression analysis system | |
| KR101916989B1 (ko) | 핵산 서열분석을 수행하기 위한 회전식 플랫폼 | |
| JP2005505269A (ja) | 核酸のアーカイブ | |
| JPH09511407A (ja) | 中規模ポリヌクレオチド増幅装置 | |
| EP0863213A1 (en) | Thermal cycler equipment | |
| EP2294214A2 (en) | Compositions and methods for providing substances to and from an array | |
| WO2011006671A1 (en) | A microfabricated device for metering an analyte | |
| Phaneuf et al. | Sensitive, microliter PCR with consensus degenerate primers for Epstein Barr virus amplification | |
| CN103074203A (zh) | 用于核酸扩增反应的微芯片及其制造方法 | |
| WO2013035867A1 (ja) | マルチ核酸反応具およびそれを用いた検出方法 | |
| JP6116836B2 (ja) | マルチ核酸反応具およびそれを用いた検出方法 | |
| US20100196884A1 (en) | Nucleic Acid Preparation | |
| JP2014030411A (ja) | 核酸増幅反応用マイクロチップ | |
| JP4556230B2 (ja) | 核酸検出容器 | |
| WO2008001691A1 (en) | Method of treating sample | |
| WO2025054265A1 (en) | Methods for anchoring lyophilized reagents to a substrate and complexes formed therefrom | |
| JP2008154490A (ja) | 複数種類の標的塩基配列を同時に増幅するために用いられる基板と、該基板を用いた塩基配列の増幅方法 | |
| HK1200498B (zh) | 生化分析的系统、设备和方法 | |
| HK1092157A (en) | Nucleic acid preparation |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A711 | Notification of change in applicant |
Free format text: JAPANESE INTERMEDIATE CODE: A711 Effective date: 20150911 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A821 Effective date: 20150911 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20161108 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20161108 |
|
| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20170920 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20171024 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20180124 |
|
| A711 | Notification of change in applicant |
Free format text: JAPANESE INTERMEDIATE CODE: A712 Effective date: 20180320 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A821 Effective date: 20180320 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20180703 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20180928 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20190219 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20190424 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20190625 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20190717 |
|
| R150 | Certificate of patent or registration of utility model |
Ref document number: 6559568 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |