JP6553454B2 - Antiperspirant composition - Google Patents

Description

  The present invention relates to antiperspirant compositions.

  Heretofore, there has been proposed a deodorant composition which is excellent in antiperspirant effect and durability of antiperspirant effect by containing chlorhydroxyaluminum and a specific anionic polymer and forming a film on the skin (for example, a patent) Reference 1 and 2). However, the above-mentioned proposal has a problem that as perspiration amount and perspiration time increase, durability of antiperspirant effect and antiperspirant effect decreases. Moreover, the said proposal is not fully examined about the ease of application to the skin, the lack of feeling of skin firmness, the non-stickiness of the skin, and the lack of irritation to the skin.

  Therefore, even when the amount of sweating and the time of sweating increase, the antiperspirant effect and the durability of the antiperspirant effect are excellent, and the ease of application to the skin, no feeling of skin firmness, and good non-stickiness of the skin are good. It is desirable to provide an antiperspirant composition that is less irritating to the skin.

JP 2014-015421 A International Publication No. 2013/081055 Pamphlet

  An object of the present invention is to solve the above-mentioned problems in the prior art and to achieve the following objects. That is, according to the present invention, even when the amount of sweating and the time of sweating increase, the antiperspirant effect and the durability of the antiperspirant effect are excellent, easiness to apply to the skin, no sense of skin firmness, and no stickiness of the skin It is an object of the present invention to provide an antiperspirant composition which is good and less irritating to the skin.

  As a result of intensive studies conducted by the inventor to solve the above problems, (A) at least one antiperspirant selected from (A) aluminum compounds, zirconium compounds, and complexes thereof, and (B) vinyl-type anionic A polymer, (C) ethanol, (D) a hydrophobized modified alkyl cellulose, and (E) a neutralizing agent, wherein the content of (C) ethanol is 50% by mass to 85% by mass, The mass ratio (B / D) of the content (% by mass) of the (B) vinyl type anionic polymer and the content (% by mass) of the (D) hydrophobized modified alkyl cellulose is 0.6 to 28. The antiperspirant composition which is an antiperspirant effect and the durability of the antiperspirant effect is excellent even if the amount of perspiration and the perspiration time are increased by the synergetic effect of each component, the ease of applying to the skin, the firmness of the skin No feeling and sticky skin Is is good, and found that skin irritation is less.

This invention is based on the said knowledge by this inventor, and as a means for solving the said subject, it is as follows.
<1> (A) at least one antiperspirant selected from an aluminum compound, a zirconium compound, and a complex thereof
(B) vinyl type anionic polymer,
(C) with ethanol
(D) a hydrophobically modified alkyl cellulose;
(E) containing a neutralizing agent,
The content of the (C) ethanol is 50% by mass to 85% by mass,
The mass ratio (B / D) of the content (mass%) of the (B) vinyl-type anionic polymer and the content (mass%) of the (D) hydrophobized modified alkyl cellulose is 0.6 to 28. It is an antiperspirant composition characterized by being.
<2> (A) The antiperspirant composition according to <1>, wherein the antiperspirant is chlorhydroxyaluminum.
<3> (B) The vinyl type anionic polymer is selected from (vinyl acetate / crotonic acid / vinyl neodecanoate) copolymer, (vinyl methyl ether / ethyl maleate) copolymer, and (vinyl methyl ether / butyl maleate) copolymer The antiperspirant composition according to any one of <1> to <2>, which is at least one selected from the group consisting of
<4> (D) The antiperspirant composition according to any one of <1> to <3>, wherein the hydrophobized modified alkyl cellulose is stearoxyhydroxypropyl methylcellulose.
<5> (E) The antiperspirant composition according to any one of <1> to <4>, wherein the neutralizing agent is 2-amino-2-methyl-1-propanol.
<6> (A) The antiperspirant content is 6% by mass to 15% by mass,
(B) The content of the vinyl type anionic polymer is 1% by mass to 2.5% by mass,
(C) The content of ethanol is 60% by mass to 75% by mass,
(D) The content of hydrophobized modified alkyl cellulose is 0.2% by mass to 0.6% by mass,
(E) It is an antiperspirant composition in any one of said <1> to <5> whose content of a neutralizing agent is 0.1 mass%-0.3 mass%.
<7> The mass ratio (B / D) of the content (mass%) of the (B) vinyl-type anionic polymer and the content (mass%) of the (D) hydrophobized modified alkyl cellulose is from 1.25 to It is an antiperspirant composition in any one of said <1> to <6> which is 12.5.
<8> The antiperspirant composition according to any one of <1> to <7>, which is any one selected from a roll-on type, a gel type, a lotion type, and a mist type.

  According to the present invention, it is possible to solve the above-described problems and achieve the above-described object, and even when the sweating amount and the sweating time are increased, the antiperspirant effect and the persistence of the antiperspirant effect are excellent, and the skin. It is possible to provide an antiperspirant composition having good ease of application, no feeling of skin firmness, and non-sticky skin, and less irritation to the skin.

(Antiperspirant composition)
The antiperspirant composition of the present invention comprises (A) an antiperspirant, (B) a vinyl type anionic polymer, (C) ethanol, (D) hydrophobized modified alkyl cellulose, and (E) a neutralizing agent. And, if necessary, contain other ingredients.

<(A) Antiperspirant>
The antiperspirant of the said (A) component is contained in order to improve the antiperspirant effect.

  Examples of the antiperspirant of the component (A) include aluminum compounds, zirconium compounds, and complexes thereof. These may be used alone or in combination of two or more.

As said aluminum compound, aluminum salt etc. are mentioned, for example.
Examples of the aluminum salt include aluminum chloride, aluminum sulfate, potassium aluminum sulfate, aluminum acetate, chlorohydroxyaluminum, bromohydroxyaluminum, and allantochlorohydroxyaluminum. These may be used alone or in combination of two or more.

Examples of the zirconium compound include zirconium salts.
Examples of the zirconium salt include zirconium chloride, hydroxy zirconium chloride, zirconium hydroxide, zirconium ammonium carbonate, potassium zirconium carbonate, zirconium sulfate and the like. These may be used alone or in combination of two or more.

  Examples of these complexes include complexes of an aluminum compound and glycine, complexes of an aluminum compound and propylene glycol, and complexes of a mixture of an aluminum compound and a zirconium compound and glycine. These may be used alone or in combination of two or more.

  As a complex of the aluminum compound and glycine, for example, aluminum chloride / glycine complex, aluminum sulfate / glycine complex, aluminum potassium sulfate / glycine complex, aluminum acetate / glycine complex, chlorohydroxyaluminum / glycine complex, bromohydroxyaluminum / glycine And complexes such as allantoin chlorohydroxyaluminum-glycine complex. These may be used alone or in combination of two or more.

  As a complex of the aluminum compound and propylene glycol, for example, aluminum chloride / propylene glycol complex, aluminum sulfate / propylene glycol complex, aluminum potassium sulfate / propylene glycol complex, aluminum acetate / propylene glycol complex, chlorhydroxyaluminum / propylene glycol complex Bromohydroxyaluminum / propylene glycol complex, allantoinchlorohydroxyaluminum / propylene glycol complex, and the like. These may be used alone or in combination of two or more.

Examples of the complex of the mixture of aluminum compound and zirconium compound with glycine include: aluminum chloride / zirconium compound / glycine complex, aluminum sulfate / zirconium compound / glycine complex, aluminum potassium sulfate / zirconium compound / glycine complex, aluminum acetate / zirconium Examples include compounds and glycine complexes, chlorohydroxyaluminum / zirconium compounds and glycine complexes, bromohydroxyaluminum / zirconium compounds and glycine complexes, and allantoin chlorohydroxyaluminum / zirconium compounds and glycine complexes. These may be used alone or in combination of two or more.
Among these, aluminum chloride, aluminum sulfate, potassium aluminum sulfate, aluminum acetate, chlorohydroxyaluminum, allantoin chlorohydroxyaluminum, chlorohydroxyaluminum / propylene glycol complex, chlorhydroxyaluminum, from the viewpoint of antiperspirant effect and durability of antiperspirant effect. Hydroxyaluminum / zirconium glycine complex is preferable, chlorhydroxyaluminum, chlorhydroxyaluminum propylene glycol complex, potassium aluminum sulfate, chlorhydroxyaluminum / zirconium glycine complex are more preferable, and chlorhydroxyaluminum is particularly preferable.

  The content of the antiperspirant of the component (A) is the total amount of the antiperspirant composition from the viewpoints of antiperspirant effect, durability of antiperspirant effect, no feeling of skin firmness and no stickiness of the skin. On the other hand, 4 mass%-20 mass% are preferable, and 6 mass%-15 mass% are more preferable. If the content is less than 4% by mass, the antiperspirant effect and the persistence of the antiperspirant effect may be insufficient, and if it exceeds 20% by mass, the feeling of skin firmness and the skin Sometimes the stickiness is not enough.

<(B) Vinyl type anionic polymer>
The vinyl type anionic polymer of the component (B) is contained in order to improve the sustainability of the antiperspirant effect by a film formed on the skin.

  Examples of the vinyl type anionic polymer of the component (B) include a copolymer obtained by copolymerizing an anionic monomer and at least one of a vinyl ether compound and a vinyl ester compound; vinyl ester unit in the copolymer And a copolymer in which a vinyl alcohol unit is formed in the copolymer by further hydrolysis. These may be used alone or in combination of two or more.

  Examples of the anionic monomer include crotonic acid, maleic acid, maleic acid monoester, itaconic acid and the like. These may be used alone or in combination of two or more.

  Examples of the vinyl ether compounds include vinyl methyl ether, vinyl ethyl ether, vinyl hexyl ether, vinyl octyl ether, vinyl decyl ether, vinyl ethyl hexyl ether, vinyl methoxyethyl ether, vinyl ethoxyethyl ether, vinyl chloroethyl ether, 1-methyl -2,2-Dimethylpropyl vinyl ether, 2-ethyl butyl vinyl ether, hydroxyethyl vinyl ether, diethylene glycol vinyl ether, dimethylaminoethyl vinyl ether, diethylaminoethyl vinyl ether, butylaminoethyl vinyl ether, benzyl vinyl ether, tetrahydrofurfuryl vinyl ether, vinyl phenyl ether, vinyl tolyl Ether, vinyl chlorophenyl ether , Vinyl 2,4-dichlorophenyl ether, vinyl naphthyl ether, and vinyl anthranyl ether. These may be used alone or in combination of two or more.

  Examples of the vinyl ester compound include vinyl butyrate, vinyl isobutyrate, vinyl trimethyl acetate, vinyl diethyl acetate, vinyl barato, vinyl caproate, vinyl chloroacetate, vinyl dichloro acetate, vinyl methoxy acetate, vinyl butoxy acetate And vinyl phenyl acetate, vinyl acetoacetate, vinyl lactate, vinyl-β-phenyl butyrate, vinyl cyclohexyl carboxylate and the like. These may be used alone or in combination of two or more.

  Examples of the vinyl type anionic polymer of the component (B) include (vinyl acetate / crotonic acid / vinyl neodecanoate) copolymer (trade name: RESYN 28-2930, manufactured by Akzo Nobel KK), (vinyl methyl ether / maleic acid) Alkyl) copolymer (trade name: GANTREZ ES-225, trade name: ES-425, trade name: SP-215, manufactured by ISP Japan Ltd.), vinyl acetate / crotonic acid copolymer (trade name: Resin 28- 1310, National Starch Co., Ltd., vinyl acetate / crotonic acid / vinyl propionate copolymer (trade name: Rubiset CAP, manufactured by BASF), vinyl alcohol / itaconic acid copolymer (trade name: KM-118, manufactured by Kuraray Co., Ltd.) Etc. These may be used alone or in combination of two or more. Among these, (vinyl acetate / crotonic acid / vinyl neodecanoate) copolymers and (vinyl methyl ether / alkyl maleate) copolymers are preferable from the viewpoint of the persistence of the antiperspirant effect, and (vinyl acetate / crotonic acid / vinyl neodecanoate) are preferable. ) Copolymers are more preferred. The (vinyl acetate / crotonic acid / vinyl neodecanoate) copolymer means a copolymer obtained by copolymerizing vinyl acetate, crotonic acid and vinyl neodecanoate.

  Examples of the (vinyl methyl ether / alkyl maleate) copolymer include (vinyl methyl ether / maleic acid) copolymer (trade name: Gantrez AN, manufactured by ISP Japan Ltd.), (vinyl methyl ether / ethyl maleate) Copolymers (trade name: Gantrez ES-225, manufactured by ISP Japan Ltd.), (vinyl methyl ether / butyl maleate) copolymer (trade name: Gantrez ES-425, manufactured by ISP Japan Ltd.), etc. . These may be used alone or in combination of two or more. Among these, (vinyl methyl ether / ethyl maleate) copolymer and (vinyl methyl ether / butyl maleate) copolymer are preferable from the viewpoint of the antiperspirant effect. The (vinyl methyl ether / ethyl maleate) copolymer means a copolymer obtained by copolymerizing vinyl methyl ether and ethyl maleate, and the (vinyl methyl ether / butyl maleate) copolymer means vinyl methyl. It means a copolymer obtained by copolymerizing ether and butyl maleate.

  The content of the vinyl-type anionic polymer of the component (B) is the total amount of the antiperspirant composition in view of the durability of the antiperspirant effect, the no firmness of the skin and the no tackiness of the skin. 0.5 mass% to 3 mass% is preferable, and 1 mass% to 2.5 mass% is more preferable. If the content is less than 0.5% by mass, the persistence of the antiperspirant effect may be insufficient, and if it exceeds 3% by mass, the skin does not have a feeling of firmness and no stickiness. May be inadequate.

<(C) ethanol>
The component (C) ethanol is contained to improve the skin's tackiness.

  As ethanol of the said (C) component, absolute ethanol, 95 volume% ethanol (standard value 95 volume%-95.5 volume%) etc. are mentioned, for example. These may be used alone or in combination of two or more.

  The content of ethanol of the component (C) is the total amount of the antiperspirant composition in view of the antiperspirant effect, the durability of the antiperspirant effect, the non-stickiness of the skin, and the non-irritability to the skin. And 50% by mass to 85% by mass in terms of absolute ethanol, preferably 60% by mass to 75% by mass. When the content of ethanol is less than 50% by mass, the skin is not tacky enough, and when it exceeds 85% by mass, the antiperspirant effect and the antiperspirant effect are insufficiently sustained, and sensitive skin Causes skin irritation.

As content of ethanol of the said (C) component, when a plant extract etc. are contained as another component, it is total content of the absolute ethanol containing the ethanol carried in from these components.
The content (mass%) converted to absolute ethanol in the case of using 95% by volume of ethanol can be determined by the following formula 1 (independent medical corporation medical device medical device general transmission document 038-1309. Pdf) and formula 2 Can.
Ethanol mass% = volume% × 0.79422 (specific gravity of 100% by volume at 15 ° C.) / D (specific gravity at 15 ° C.) Formula 1
= (95 x 0.79422) /0.81639
= 92.42
-Absolute ethanol content (mass%) = 95 vol% ethanol content (mass%) x 92.42 / 100 Formula 2

<(D) Hydrophobicized modified alkyl cellulose>
The hydrophobized modified alkyl cellulose of the component (D) is contained to improve the durability of the antiperspirant effect even when the amount of perspiration and the perspiration time increase.

ただし、前記一般式（Ｄ１）中、Ｒ^１、Ｒ^２、及びＲ^３は、それぞれ独立に、水素原子、アルキル基、及びアルコキシ基のいずれかを示し、前記Ｒ^１、前記Ｒ^２、及び前記Ｒ^３から選択される少なくとも一つはアルコキシ基を示し、ｎは１００〜１０,０００の整数を示す。 The hydrophobized modified alkyl cellulose of the component (D) is a hydrophobized product of modified alkyl cellulose, and a compound represented by the following general formula (D1) is preferable.

However, in said general formula (D1), R ¹ , R ² and R ³ each independently represent a hydrogen atom, an alkyl group or an alkoxy group, and said R ¹ , said R ² and said At least one selected from R ³ represents an alkoxy group, and n represents an integer of 100 to 10,000.

  The alkoxy group may be linear or branched. Among these, from the viewpoint of high hydrophobicity, a long-chain alkoxy group is preferable, a long-chain alkoxy group having 12 or more carbon atoms is more preferable, and a long-chain alkoxy group having 12 to 22 carbon atoms is particularly preferable.

  Examples of the alkoxy group include dodecyloxy group (lauroxy group), tridecyloxy group, tetradecyloxy group (myristyloxy group), pentadecyloxy group, hexadecyloxy group (secyloxy group), heptadecyloxy group, octadecyloxy group (stearoxy group). Group), nonadecyloxy group, eicosyloxy group, henecosyloxy group, docosyloxy group and the like. Among these, an octadecyloxy group (stearoxy group) is preferable from the viewpoint of sustaining the antiperspirant effect.

  Examples of the alkyl group include methyl group, ethyl group, propyl group, isopropyl group, butyl group, isobutyl group, t-butyl group and cyclohexyl group.

As the kinematic viscosity of the hydrophobically-modified alkyl cellulose component (D), at 25 ° ^C., preferably from 20mm ² / s~300mm 2 / s, in terms of ^usability, 70mm ² / ^s~110mm 2 / s Gayori preferable. The kinematic viscosity can be measured using an Ubbelohde viscometer.

Examples of the hydrophobized modified alkyl cellulose of the component (D) include hydrophobized hydroxyalkyl cellulose and the like.
As the hydrophobized hydroxyalkyl cellulose, for example, dodecyloxy hydroxyalkyl cellulose (lauroxy hydroxyalkyl cellulose), tridesiloxy hydroxyalkyl cellulose, tetradecyloxy hydroxyalkyl cellulose (myristyloxy hydroxyalkyl cellulose), pentadecyloxy hydroxycellulose Alkylcellulose, hexadecyloxyhydroxyalkylcellulose (cetyloxyhydroxyalkylcellulose), heptadecyloxyhydroxyalkylcellulose, octadecyloxyhydroxyalkylcellulose (stearoxyhydroxyalkylcellulose), nonadecyloxyhydroxyalkylcellulose, eicosyloxyhydroxyalkylcellulose , Henei Kosiloxy hydroxyl Le cellulose, docosyl siloxy hydroxyalkyl cellulose. These may be used alone or in combination of two or more. Among these, octadecyloxyhydroxyalkylcellulose (stearoxyhydroxyalkylcellulose) is preferable, and octadecyloxyhydroxypropylmethylcellulose (stearoxyhydroxypropylmethylcellulose) is more preferable, from the viewpoint of the antiperspirant effect.

  As the hydrophobized modified alkyl cellulose of the component (D), a commercial product may be used, and as the commercial product, for example, trade name: Sangerose 60L, trade name: Sangerose 60M, trade name: Sangerose 90L , Trade name: Sangelose 90M (component name: stearoxyhydroxypropyl methylcellulose, manufactured by Daido Kasei Kogyo Co., Ltd.), and the like. These may be used alone or in combination of two or more.

  The content of the hydrophobized modified alkyl cellulose of the component (D) is the total amount of the antiperspirant composition from the viewpoint of the durability of the antiperspirant effect, the ease of application to the skin and the lack of firmness of the skin. 0.1 mass%-1 mass% are preferable, and 0.2 mass%-0.6 mass% are more preferable. When the content is less than 0.1% by mass, durability of the antiperspirant effect and ease of application to the skin may be insufficient. When the content exceeds 1% by mass, it is easy to apply to the skin. And the feeling of skin firmness may be inadequate.

<(E) neutralizer>
The neutralizing agent of the component (E) is contained to improve the durability of the antiperspirant effect.

  Examples of the neutralizing agent for the component (E) include monoethanolamine, diethanolamine, triethanolamine, 2-amino-2-methyl-1-propanol and the like. These may be used alone or in combination of two or more. Among these, 2-amino-2-methyl-1-propanol is preferable from the viewpoint of durability of the antiperspirant effect.

  The content of the neutralizing agent of the component (E) is 0.05% by mass to 0.3% by mass with respect to the total amount of the antiperspirant composition from the viewpoint of durability of the antiperspirant effect and skin irritation. % Is preferable, and 0.1% by mass to 0.3% by mass is more preferable. If the content is less than 0.05% by mass, durability of the antiperspirant effect may be insufficient, and if it exceeds 0.3% by mass, skin irritation may occur on sensitive skin.

  As an apparatus used for the neutralization by the neutralizing agent of the said (E) component, Metrom potential difference automatic titration apparatus (made by Metrome Japan KK) etc. are mentioned, for example.

[Mass ratio (B / D)]
As a mass ratio (B / D) of the content (mass%) of the (B) vinyl type anionic polymer and the content (mass%) of the (D) hydrophobized modified alkyl cellulose, It is 0.6 to 28, and preferably 1.25 to 12.5 from the viewpoint of durability, ease of application to the skin, lack of firmness of the skin and non-stickiness of the skin. When the mass ratio (B / D) is less than 0.6, the ease of application to the skin and the lack of firmness of the skin become insufficient, and when it exceeds 28, the ease of application to the skin, skin Lack of firmness and lack of stickiness on the skin will be inadequate.

<Other ingredients>
There is no restriction | limiting in particular as said other component, According to the objective, it can select suitably, In the range which does not impair the effect of this invention besides each component of said (A)-said (D) component, Other ingredients can be included. Examples of the other components include oil and fat compounds, wax compounds, silicone compounds, hydrocarbon oils, higher fatty acids, higher alcohols, surfactants, polymer compounds other than the component (B), antioxidants, dyes, and emulsions. Stabilizers, pH adjusters, preservatives, UV absorbers, chelating agents, moisturizers, thickeners such as hydroxypropyl cellulose other than the above component (D), cooling agents, anti-inflammatory agents, bactericides such as isopropyl cellulose, Examples include amino acids, vitamins, fragrances, and various plant extracts.

-PH-
The pH of the antiperspirant composition at 25 ° C. is preferably 3 to 4.5 from the viewpoints of antiperspirant effect, durability of antiperspirant effect, and no stickiness of the skin. When the pH is less than 3, the antiperspirant effect and the persistence of the antiperspirant effect may be insufficient, and when it is more than 4.5, the non-greasy skin may be insufficient. .

-Viscosity-
There is no restriction | limiting in particular as a viscosity of the said antiperspirant composition, Although it can select suitably according to the objective, When it is liquid, it is 25 from the point of the persistence of the antiperspirant effect, and no stickiness of skin. At m ° C., 1 mPa · s to 3,000 mPa · s is preferable, and 5 mPa · s to 1,600 mPa · s is more preferable. When the viscosity is less than 1 mPa · s, the durability of the antiperspirant effect may be insufficient, and when it is more than 3,000 mPa · s, the skin may not be sufficiently tacky.
The viscosity is, for example, No. 1 at 25 ° C. using a BL type viscometer. 1-3 rotors can be used and measured at 60 rpm for 1 minute.

-Dosage form-
There is no restriction | limiting in particular as a dosage form of the said antiperspirant composition, According to the objective, it can select suitably, For example, solid state type, semi-solid state type, gel-like type, liquid type etc. are mentioned. Among them, gel-type and liquid-type are preferable in that they are applied to the skin in a state dissolved in water, which is effective for exhibiting the effect, can be applied in high adhesion, and can exhibit high antiperspirant effect. Type is more preferred.
Examples of the solid type include a stick type and a sheet type.
Examples of the semi-solid type include a cream type.
Examples of the gel type include a gel type.
Examples of the liquid type include a roll-on type, a lotion type, and a mist type. Among these, the roll-on type is preferable from the viewpoint of the antiperspirant effect.

When the antiperspirant composition is a roll-on type, it is preferable to use an antiperspirant product comprising the antiperspirant composition and a roll-on container having an application ball filled with the composition. The roll-on type preparation is contained in a known roll-on container, and the antiperspirant composition is attached to a ball held in a holder and rotatably held with a part thereof exposed in the roll-on container, at the time of use Such balls can be attached to the skin and applied.
Further, a gel preparation which is filled with the antiperspirant composition in a bottle container and which is applied as it is using a container, a gel preparation which is applied using a fingertip or a hand, and a lotion preparation can be suitably used.

-Manufacturing method-
There is no restriction | limiting in particular as a manufacturing method of the said antiperspirant composition, According to the objective, it can select suitably, For example, said (A)-said (E) component, and said other components (antiperspirant) It can be adjusted by mixing the remaining amount so that the whole composition becomes 100% by mass. Specifically, the component (B) is charged into the component (C) and dissolved uniformly, and then the component (A) is charged. Thereafter, the component (D), water and the other components are added, and uniformly dissolved and mixed. Thereafter, the antiperspirant composition can be obtained by neutralization with the component (E).
There is no restriction | limiting in particular as an apparatus which prepares the said antiperspirant composition, According to the objective, it can select suitably, For example, it is equipped with several stirring blade (a propeller, a turbine, a disper, etc.) which can carry out whole mixing with shear. Stirring apparatus etc. are mentioned. In the preparation of the antiperspirant composition, the components (A) to (E) and the other components may be used alone or in combination of two or more components. You may use in the state.

-Container-
Examples of the container include a roll-on container, a bottle container for gel, a bottle container for lotion, and a trigger type spray container for mist. Among these, a roll-on container is preferable from the viewpoint of easy application to the skin. The roll-on container can be suitably used in that the antiperspirant composition can be applied to the skin with high adhesion, and an antiperspirant effect can be exhibited. The roll-on container is not particularly limited as long as it can be filled with the antiperspirant composition, and can be appropriately selected according to the purpose. For example, those described in JP-A-2005-186997 Can be mentioned.

  As the roll-on container, for example, a bottle (material: HDPE natural, full filling internal volume: about 56 mL, body diameter: about 33 mm, height: about 87 mm, made by Yoshino Kogyo Co., Ltd.), ring (material: LLDPE natural) , Outer diameter: about 26 mm, height: about 18 mm, manufactured by Yoshino Kogyo Co., Ltd.), balls (material: PP white, diameter: about 20 mm, manufactured by Yoshino Kogyo Co., Ltd.), and the like.

  As the above-mentioned bottle container for gel, for example, a bottle (trade name: TOMII, material: HDPE natural, full filling volume: about 34 mL, body diameter: about 39 mm × 24 mm (oval) diameter, height: about 76 mm, Takemoto container Made in Japan Co., Ltd., Inside stopper (product name: TO cap nozzle B, material: PE natural, outer diameter: about 12 mm, height: about 13 mm, made by Takemoto Container Co., Ltd.), cap (product name: TO cap, material : AS / PP white, outer diameter: diameter about 37 mm × 23 mm (oval), height: about 22 mm, manufactured by Takemoto Container Co., Ltd., etc. can be used.

  As the bottle container for lotion, for example, a bottle (trade name: TOM III-50, material: HDPE natural, full filling volume: about 34 mL, body diameter: about 42 mm × 29 mm (oval) diameter, height: about 88 mm, Takemoto Container Co., Ltd.), Inner plug (Product name: TO Cap Nozzle A, Material: PE Natural, Outer Diameter: about 12mm, Height: About 13mm, Takemoto Container Co., Ltd.), Cap (Product Name: TOMIII Cap) Material: PP white, outer diameter: about 37 mm × 25 mm (oval), height: about 24 mm, manufactured by Takemoto Container Co., Ltd., etc. can be used.

  Examples of the trigger container for mist include, for example, a bottle (trade name: PH-100, material: PE natural, full capacity: about 100 mL, body diameter: about 40 mm in diameter, height: about 120 mm, Kamimura Chemical Co., Ltd. Made (trade name: Z-305, average diameter of spray hole: 0.45 mm, manufactured by Mitani Valve Co., Ltd.) or the like can be used.

-Application-
The antiperspirant composition of the present invention is excellent in antiperspirant effect and durability of antiperspirant effect even when the amount of perspiration and perspiration time increase, ease of application to the skin, lack of feeling of skin tightness, and skin It has good non-stickiness and is less irritating to the skin, so it can be applied to, for example, cosmetics, medicines, quasi-drugs, etc. Antiperspirant, deodorant, antiperspirant, deodorant, deodorant And deodorant spray, and particularly suitable for roll-on type antiperspirant and the like.

  Hereinafter, the present invention will be more specifically described based on examples and comparative examples, but the present invention is not limited to the following examples. In addition, content of each component of the description of an Example and a comparative example is the value all converted into a pure part.

(Examples 1-30 and Comparative Examples 1-10)
An antiperspirant composition having the compositions and contents shown in Tables 1 to 8 below was prepared by the following method. That is, the component (B) was added to the component (C) and dissolved uniformly, and then the component (A) was added. Thereafter, the component (D) or the component (D '), purified water, and the common component were charged, and uniformly dissolved and mixed. Then, it neutralized with (E) component and obtained the composition of pH 3-4.5. Note that the antiperspirant composition of Comparative Example 3 could not be formulated because it did not contain the component (C) ethanol serving as a solvent. Moreover, neutralization by the (E) component was confirmed using a Metrohm potentiometric automatic titrator (manufactured by Metrohm Japan).
Next, 40 mL of the antiperspirant compositions of Examples 1 to 25, 29 to 30, and Comparative Examples 1, 2, and 4 to 10 were filled in a roll-on container (container A) having the following specifications. In addition, the antiperspirant composition of Example 26 is in a bottle container for gel (container B) of the following specification, and the antiperspirant composition of Example 27 is in a bottle container for lotion of the following specification (container C). 20 mL of each of the 28 antiperspirant compositions was filled in a mist bottle container (container D) of the following specification.

-Roll-on container (container A)-
・ Bottle (material: HDPE natural, full filling inner volume: about 56 mL, body diameter: about 33 mm in diameter, height: about 87 mm, made by Yoshino Kogyo Co., Ltd.)
-Ring (material: LLDPE natural, outer diameter: about 26 mm, height: about 18 mm, manufactured by Yoshino Kogyo Co., Ltd.)
・ Ball (material: PP white, diameter: about 20 mm, made by Yoshino Industry Co., Ltd.)

-Bottle container for gel (container B)-
・ Bottle (trade name: TOMII, material: HDPE natural, full fill volume: about 34 mL, body diameter: about 39 mm × 24 mm in diameter (oval), height: about 76 mm, manufactured by Takemoto Container Co., Ltd.)
・ Inner stopper (Product name: TO cap nozzle B, Material: PE natural, Outer diameter: approx. 12 mm, Height: approx. 13 mm, Takemoto Container Co., Ltd.)
・ Cap (trade name: TO cap, material: AS / PP white, outer diameter: about 37 mm × 23 mm in diameter (oval), height: about 22 mm, manufactured by Takemoto Container Co., Ltd.)

-Bottle container for lotion (container C)-
・ Bottle (trade name: TOMIII-50, material: HDPE natural, full fill volume: about 34 mL, body diameter: about 42 mm × 29 mm in diameter (oval), height: about 88 mm, manufactured by Takemoto Container Co., Ltd.)
-Inside plug (Product name: TO cap nozzle A, material: PE natural, outer diameter: about 12 mm, height: about 13 mm, manufactured by Takemoto Container Co., Ltd.)
・ Cap (trade name: TOM III cap, material: PP white, outer diameter: about 37 mm × 25 mm (oval), height: about 24 mm, manufactured by Takemoto Container Co., Ltd.)

-Mist bottle container (container D)-
・ Bottle (trade name: PH-100, material: PE natural, full filling capacity: about 100 mL, body diameter: about 40 mm in diameter, height: about 120 mm, made by Kamimura Chemical Co., Ltd.)
・ Trigger (trade name: Z-305, average diameter of spray hole: 0.45 mm, manufactured by Mitani Valve Co., Ltd.)

  About the prepared antiperspirant compositions of Examples 1 to 30 and Comparative Examples 1, 2 and 4 to 10, "Antiperspirant effect", "Persistence of antiperspirant effect", "Skin" Ease of application to the skin, "no feeling of skin firmness", "no stickiness of the skin" and "no irritation to the skin" were evaluated. The results are shown in Tables 1 to 8. In addition, since the antiperspirant composition of the comparative example 3 does not contain the ethanol of the (C) component used as a solvent, it could not formulate, and was not able to be evaluated.

−制汗効果、及び制汗効果の持続性の評価基準−
◎ ：制汗率が５６％以上１００％以下
◎〜○ ：制汗率が４６％以上５６％未満
○ ：制汗率が３６％以上４６％未満
△ ：制汗率が２６％以上３６％未満
× ：制汗率が０％以上２６％未満 <Antiperspirant effect and durability of antiperspirant effect>
For 20 expert panelists, apply 0.5g of antiperspirant composition as a sample to the axilla on one side and use an exercise bike (trade name: FB-300HP, made by Remark) under an environment of 38 ° C and 40% relative humidity. I did exercise for 15 minutes. Then, the axilla (sample application part) which apply | coated the sample using the perspiration meter (brand name: SKN-2000, Nishizawa Denki Keiki Seisakusho Co., Ltd. product), and the other axilla of the sample non-application (sample non-application part) The amount of sweating was measured, and the antiperspirant rate was determined from the following formula. The result shows the average value of 20 specialized panelists. From the result of the antiperspirant rate, the "antiperspirant effect" was evaluated based on the following evaluation criteria. Thereafter, the exercise by the exercise bike was further performed for 30 minutes, and “sustainability of antiperspirant effect” was evaluated by the same evaluation method.

-Evaluation criteria of antiperspirant effect and durability of antiperspirant effect-
:: Antiperspirant rate of 56% to 100% 汗 ~: Antiperspirant rate of 46% to 56% ○: Antiperspirant rate of 36% to 46%%: Antiperspirant rate of 26% to 36% X: Antiperspirant rate is 0% or more and less than 26%

<Ease of application to skin>
For 20 professional panelists, 0.5 g of each antiperspirant composition was applied to the axilla, and “easy to apply to skin” was evaluated based on the following evaluation criteria.
-Evaluation criteria-
:: 19 to 20 expert panelists answered that it is easy to apply to the skin 〜 ~ ○: 16 to 18 expert panelists answered that it is easy to apply to the skin ○: 11 to 20 expert panelists Answer: More than 15 people can easily apply to the skin :: Answer: More than 6 out of 20 specialist panelists can easily apply to the skin Easy to respond: ×: 5 out of 20 expert panelists say it is easy to apply to the skin

<No feeling of skin firmness>
After applying 0.5 g of each antiperspirant composition to the axilla and drying it for 20 expert panelists, "the feeling of no skin firmness" was evaluated based on the following evaluation criteria.
-Evaluation criteria-
:: 19 or more and 20 or less of 20 specialized panelists answered that there is no feeling of skin firming 〜 ○: 16 or more of 18 specialized panelists and less than 18 people answered that there is no skin pinching feeling ○:: Specialized paneler 11 or more and 15 or less out of 20 answered that there is no skin firmness feeling :: 6 or more out of 20 specialized panelists and less than 10 answered that there is no skin firmness feeling out ×: 5 or less out of 20 specialized panelists If there is no feeling of skin tightening

<No sticky skin>
0.5 g of each antiperspirant composition was applied to the axilla to 20 specialized panelists, and immediately after application until each antiperspirant composition dried, “skin tackiness was determined based on the following evaluation criteria. I evaluated "Masa".

-Evaluation criteria-
:: 19 or more and 20 or less of the 20 expert panelists answered that the skin was not sticky 〜 ○: 16 or more and 18 or less of the 20 expert panelists answered that the skin was not tacky ○: 20 specialized panelists Among them, 11 or more and 15 or less answered that the skin was not sticky △: 6 or more out of 20 specialized panelists and 10 or less answered that the skin was not tacky x: or less than 5 out of 20 specialized panelists were sticky If there is no answer

<No skin irritation>
After applying 0.5 g of each antiperspirant composition to the axilla to 20 specialized panelists (sensitive skin panelers), "non-irritating to the skin" was evaluated based on the following evaluation criteria.
-Evaluation criteria-
:: 16 or more and 20 or less out of 20 specialized panelists answered that there is no skin irritation ○: 11 or more out of 20 specialized panelists and 15 or less answered that there is no skin irritation 20: 20 specialized panelists 6 to 10 of them answered that there was no irritation to the skin ×: 5 or less of 20 professional panelists answered that there was no irritation to the skin

In addition, about the detail of the various component used by the said Example and the said comparative example, it shows in following Table 9.

  The antiperspirant composition of the present invention is excellent in antiperspirant effect and durability of antiperspirant effect even when the amount of perspiration and perspiration time increase, ease of application to the skin, lack of feeling of skin tightness, and skin It has good non-stickiness and is less irritating to the skin, so it can be applied to, for example, cosmetics, medicines, quasi-drugs, etc. Antiperspirant, deodorant, antiperspirant, deodorant, deodorant It is suitable for a deodorant spray and is particularly suitable for a roll-on type antiperspirant.

Claims (5)

(A) at least one antiperspirant selected from aluminum compounds, zirconium compounds, and complexes thereof,
(B) vinyl type anionic polymer,
(C) with ethanol
(D) a hydrophobically modified alkyl cellulose;
(E) containing a neutralizing agent,
Content of said (A) antiperspirant is 4 mass%-20 mass%,
The content of the (B) vinyl-type anionic polymer is 0.5% by mass to 3% by mass,
The content of the (C) ethanol is 50% by mass to 85% by mass,
The content of the (D) hydrophobized modified alkyl cellulose is 0.1% by mass to 1% by mass,
The content of the (E) neutralizing agent is 0.05% by mass to 0.3% by mass,
The (B) vinyl type anionic polymer is selected from (vinyl acetate / crotonic acid / vinyl neodecanoate) copolymer, (vinyl methyl ether / ethyl maleate) copolymer, and (vinyl methyl ether / butyl maleate) copolymer At least one,
The (D) hydrophobized modified alkyl cellulose is stearoxyhydroxypropyl methyl cellulose,
The mass ratio (B / D) of the content (mass%) of the (B) vinyl-type anionic polymer and the content (mass%) of the (D) hydrophobized modified alkyl cellulose is 0.6 to 28. An antiperspirant composition characterized by being:   The antiperspirant composition according to claim 1, wherein (A) the antiperspirant is chlorohydroxyaluminum. (A) The antiperspirant content is 6% by mass to 15% by mass,
(B) The content of the vinyl type anionic polymer is 1% by mass to 2.5% by mass,
(C) The content of ethanol is 60% by mass to 75% by mass,
(D) The content of the hydrophobically modified alkyl cellulose is 0.2% by mass to 0.6% by mass,
The antiperspirant composition according to any one of claims 1 to 2, wherein the content of the (E) neutralizing agent is 0.1% by mass to 0.3% by mass. (B) The mass ratio (B / D) of the content (% by mass) of the vinyl type anionic polymer and the content (% by mass) of (D) the hydrophobically modified alkyl cellulose is 1.25 to 12.5. The antiperspirant composition according to any one of claims 1 to 3, which is The antiperspirant composition according to any one of claims 1 to 4, which is any one selected from roll-on type, gel type, lotion type and mist type.