JP6549151B2 - 生体試料の特性を測定するための回転可能カートリッジ - Google Patents

生体試料の特性を測定するための回転可能カートリッジ Download PDF

Info

Publication number
JP6549151B2
JP6549151B2 JP2016562788A JP2016562788A JP6549151B2 JP 6549151 B2 JP6549151 B2 JP 6549151B2 JP 2016562788 A JP2016562788 A JP 2016562788A JP 2016562788 A JP2016562788 A JP 2016562788A JP 6549151 B2 JP6549151 B2 JP 6549151B2
Authority
JP
Japan
Prior art keywords
cartridge
container
fluid
cavity
friction element
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2016562788A
Other languages
English (en)
Japanese (ja)
Other versions
JP2017516086A5 (enExample
JP2017516086A (ja
Inventor
ベーム,クリストフ
ルッツ,サッシャ
ドルビノウ,トーマス
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of JP2017516086A publication Critical patent/JP2017516086A/ja
Publication of JP2017516086A5 publication Critical patent/JP2017516086A5/ja
Application granted granted Critical
Publication of JP6549151B2 publication Critical patent/JP6549151B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • G01N35/00069Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides whereby the sample substrate is of the bio-disk type, i.e. having the format of an optical disk
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1079Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices with means for piercing stoppers or septums
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/04Closures and closing means
    • B01L2300/041Connecting closures to device or container
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/04Closures and closing means
    • B01L2300/041Connecting closures to device or container
    • B01L2300/044Connecting closures to device or container pierceable, e.g. films, membranes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0627Sensor or part of a sensor is integrated
    • B01L2300/0645Electrodes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0672Integrated piercing tool
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0803Disc shape
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0848Specific forms of parts of containers
    • B01L2300/0858Side walls
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/087Multiple sequential chambers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/16Surface properties and coatings
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0409Moving fluids with specific forces or mechanical means specific forces centrifugal forces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/06Valves, specific forms thereof
    • B01L2400/0677Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers
    • B01L2400/0683Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers mechanically breaking a wall or membrane within a channel or chamber

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
JP2016562788A 2014-05-13 2015-05-07 生体試料の特性を測定するための回転可能カートリッジ Active JP6549151B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14168042.1A EP2944965A1 (en) 2014-05-13 2014-05-13 Rotatable cartridge for measuring a property of a biological sample
EP14168042.1 2014-05-13
PCT/EP2015/060013 WO2015173097A1 (en) 2014-05-13 2015-05-07 Rotatable cartridge for measuring a property of a biological sample

Publications (3)

Publication Number Publication Date
JP2017516086A JP2017516086A (ja) 2017-06-15
JP2017516086A5 JP2017516086A5 (enExample) 2018-06-21
JP6549151B2 true JP6549151B2 (ja) 2019-07-24

Family

ID=50735885

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016562788A Active JP6549151B2 (ja) 2014-05-13 2015-05-07 生体試料の特性を測定するための回転可能カートリッジ

Country Status (6)

Country Link
US (1) US9808801B2 (enExample)
EP (2) EP2944965A1 (enExample)
JP (1) JP6549151B2 (enExample)
KR (1) KR101869184B1 (enExample)
CN (1) CN107076768B (enExample)
WO (1) WO2015173097A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3173149A1 (en) 2015-11-26 2017-05-31 Roche Diagnostics GmbH Determining a quantity of an analyte in a blood sample
WO2018043779A1 (ko) * 2016-09-05 2018-03-08 주식회사 녹십자엠에스 당화혈색소 측정용 일체형 카세트
US10137447B1 (en) * 2017-05-17 2018-11-27 Biotix, Inc. Ergonomic fluid handling tubes
MX2021002160A (es) * 2018-08-24 2021-04-28 Zoetis Services Llc Dispositivo de rotor microfluidico.
KR102599483B1 (ko) * 2018-08-24 2023-11-08 조에티스 서비시즈 엘엘씨 마이크로 유체 회전자 디바이스
US11094050B2 (en) 2018-08-24 2021-08-17 Zoetis Services Llc Systems and methods for inspecting a microfluidic rotor device
EP3840884B1 (en) 2018-08-24 2023-09-13 Zoetis Services LLC Methods for manufacturing a microfluidic rotor device
KR102600016B1 (ko) 2018-08-24 2023-11-09 조에티스 서비시즈 엘엘씨 마이크로 유체 회전자 디바이스
CN109991392B (zh) * 2019-04-11 2021-07-30 中原工学院 一种用于土工试验液塑限联合测定的三瓣皿及测试方法
CN118125056A (zh) * 2019-05-03 2024-06-04 简·探针公司 用于分析系统的容器输送系统
WO2023102427A1 (en) * 2021-11-30 2023-06-08 Gregor Diagnostics Sample collection device and system
US20240377337A1 (en) * 2023-05-11 2024-11-14 Instrumentation Laboratory Company Cartridges and uses thereof
DE102023208589A1 (de) * 2023-09-06 2025-03-06 Robert Bosch Gesellschaft mit beschränkter Haftung Freisetzvorrichtung für ein Analysegerät zum Analysieren einer in einer Kartusche enthaltene Probe, Analysegerät und Verfahren zum Betreiben eines Analysegerätes

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4812294A (en) * 1986-02-28 1989-03-14 Automated Diagnostic Systems, Inc. Specimen processing system
EP0533801B1 (en) * 1990-06-15 1994-08-10 Chiron Corporation Self-contained assay assembly and apparatus
US6309875B1 (en) * 2000-02-29 2001-10-30 Agilent Technologies, Inc. Apparatus for biomolecular array hybridization facilitated by agitation during centrifuging
KR100566459B1 (ko) * 2001-05-25 2006-03-31 가부시키가이샤 히타치세이사쿠쇼 화학 물질 정제 구조체
US20040131500A1 (en) * 2002-01-18 2004-07-08 Chow Herbert S. Device and method for evaluating platelets
US20030219890A1 (en) * 2002-05-21 2003-11-27 Gordon Gary B. Probe array bio-analysis by centrifuging shallow reaction cell
US20050169804A1 (en) * 2004-02-04 2005-08-04 Hach Company User-configurable analytical rotor system
JP2006308366A (ja) * 2005-04-27 2006-11-09 Hitachi High-Technologies Corp 化学分析装置及び化学分析カートリッジ
US20070065346A1 (en) * 2005-09-19 2007-03-22 Henry Lauren R Micro-fluidic device with neutralization and neutralization methods
JP4901333B2 (ja) * 2006-06-30 2012-03-21 ローム株式会社 マイクロチップ検査装置
EP1916524A1 (de) 2006-09-27 2008-04-30 Roche Diagnostics GmbH Rotierbares Testelement
KR20080107212A (ko) * 2007-06-05 2008-12-10 삼성전자주식회사 유체 컨테이너를 구비한 미세유동 장치
ATE541639T1 (de) 2007-11-24 2012-02-15 Hoffmann La Roche Analysesystem und verfahren zur analyse einer körperflüssigkeitsprobe auf einen darin enthaltenen analyten
US20110085950A1 (en) * 2009-10-08 2011-04-14 Samsung Electronics Co., Ltd. Centrifugal force based microfluidic system and bio cartridge for the microfluidic system
US20140037516A1 (en) * 2011-03-15 2014-02-06 Carclo Technical Plastics Limited Surface preparation
MX336625B (es) * 2011-05-18 2016-01-26 3M Innovative Properties Co Sistemas y metodos para medicion volumetrica en dispositivo de procesamiento de muestra.
GB201216454D0 (en) * 2012-09-14 2012-10-31 Carclo Technical Plastics Ltd Sample metering device

Also Published As

Publication number Publication date
CN107076768B (zh) 2018-11-30
WO2015173097A1 (en) 2015-11-19
EP2944965A1 (en) 2015-11-18
US9808801B2 (en) 2017-11-07
CN107076768A (zh) 2017-08-18
JP2017516086A (ja) 2017-06-15
US20170050185A1 (en) 2017-02-23
EP3143412A1 (en) 2017-03-22
KR101869184B1 (ko) 2018-06-19
EP3143412B1 (en) 2019-12-18
KR20160137633A (ko) 2016-11-30

Similar Documents

Publication Publication Date Title
JP6549151B2 (ja) 生体試料の特性を測定するための回転可能カートリッジ
JP6494658B2 (ja) 生体試料を分析するための回転可能カートリッジ
US11406979B2 (en) Rotatable cartridge for processing and analyzing a biological sample and dispensing method therewith
US10307757B2 (en) Rotatable cartridge with a metering chamber for analyzing a biological sample
JP7007799B2 (ja) 毛管構造を備える血液採取装置

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20180424

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20180514

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20190123

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20190225

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20190424

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20190604

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20190626

R150 Certificate of patent or registration of utility model

Ref document number: 6549151

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250