JP6525962B2 - ヒト角膜内皮細胞（ｈｃｅｃ）の同定及び分離 - Google Patents

ヒト角膜内皮細胞（ｈｃｅｃ）の同定及び分離 Download PDF

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JP6525962B2
JP6525962B2 JP2016512974A JP2016512974A JP6525962B2 JP 6525962 B2 JP6525962 B2 JP 6525962B2 JP 2016512974 A JP2016512974 A JP 2016512974A JP 2016512974 A JP2016512974 A JP 2016512974A JP 6525962 B2 JP6525962 B2 JP 6525962B2
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gene
binds
antibody
affinity reagent
protein product
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JP2016521130A (ja
JP2016521130A5 (https=
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ジェフレイ エル ゴールドバーグ
ジェフレイ エル ゴールドバーグ
ノエリア ジェイ クンゼビツキー
ノエリア ジェイ クンゼビツキー
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0621—Eye cells, e.g. cornea, iris pigmented cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5064—Endothelial cells

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
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  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Prostheses (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2016512974A 2013-05-03 2014-05-02 ヒト角膜内皮細胞（ｈｃｅｃ）の同定及び分離 Active JP6525962B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361819146P 2013-05-03 2013-05-03
US61/819,146 2013-05-03
PCT/US2014/036616 WO2014179716A2 (en) 2013-05-03 2014-05-02 IDENTIFICATION AND ISOLATION OF HUMAN CORNEAL ENDOTHELIAL CELLS (HCECs)

Related Child Applications (1)

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JP2019087341A Division JP6877483B2 (ja) 2013-05-03 2019-05-07 ヒト角膜内皮細胞（ｈｃｅｃ）の同定及び分離

Publications (3)

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JP2016521130A JP2016521130A (ja) 2016-07-21
JP2016521130A5 JP2016521130A5 (https=) 2017-06-15
JP6525962B2 true JP6525962B2 (ja) 2019-06-05

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JP2016512974A Active JP6525962B2 (ja) 2013-05-03 2014-05-02 ヒト角膜内皮細胞（ｈｃｅｃ）の同定及び分離
JP2019087341A Active JP6877483B2 (ja) 2013-05-03 2019-05-07 ヒト角膜内皮細胞（ｈｃｅｃ）の同定及び分離
JP2021074689A Active JP7752485B2 (ja) 2013-05-03 2021-04-27 ヒト角膜内皮細胞（ｈｃｅｃ）の同定及び分離
JP2023092180A Withdrawn JP2023116581A (ja) 2013-05-03 2023-06-05 ヒト角膜内皮細胞（ｈｃｅｃ）の同定及び分離

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JP2019087341A Active JP6877483B2 (ja) 2013-05-03 2019-05-07 ヒト角膜内皮細胞（ｈｃｅｃ）の同定及び分離
JP2021074689A Active JP7752485B2 (ja) 2013-05-03 2021-04-27 ヒト角膜内皮細胞（ｈｃｅｃ）の同定及び分離
JP2023092180A Withdrawn JP2023116581A (ja) 2013-05-03 2023-06-05 ヒト角膜内皮細胞（ｈｃｅｃ）の同定及び分離

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US (3) US10655102B2 (https=)
EP (2) EP2992087B1 (https=)
JP (4) JP6525962B2 (https=)
ES (1) ES2853351T3 (https=)
WO (1) WO2014179716A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021112206A (ja) * 2013-05-03 2021-08-05 エメトロープ オフサルミクス エルエルシー ヒト角膜内皮細胞（ｈｃｅｃ）の同定及び分離

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LT2788472T (lt) 2011-12-06 2019-04-10 Astellas Institute For Regenerative Medicine Kryptingos diferenciacijos būdas, skirtas ragenos endotelio ląstelių gamybai

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1130032A1 (en) 2000-02-28 2001-09-05 Gesellschaft für biotechnologische Forschung mbH (GBF) Single-chain antibodies recognizing the human vascular endothelial growth factor receptor-2 (VEGFR-2/KDR)
KR20070053152A (ko) 2003-10-10 2007-05-23 셀룰라 바이오엔지니어링 인코포레이티드 인간의 각막 내피세포 및 각막세포 이식을 위한 세포배양및 수득방법
WO2010034812A1 (en) 2008-09-25 2010-04-01 INSERM (Institut National de la Santé et de la Recherche Médicale) Monoclonal anti-claudin 1 antibodies for the inhibition of hepatitis c virus infection
WO2010084970A1 (ja) * 2009-01-23 2010-07-29 国立大学法人大阪大学 標的細胞誘導用フィーダー細胞
EP2532738B1 (en) * 2010-02-05 2016-12-21 Cornea Regeneration Institute Co., Ltd. Method for culture of corneal endothelial cells, process for production of corneal endothelial cell sheet for transplantation purposes, and culture kit for corneal endothelial cells
US9347041B2 (en) * 2011-07-15 2016-05-24 Osaka University Method for preparing corneal endothelial cell
LT2788472T (lt) 2011-12-06 2019-04-10 Astellas Institute For Regenerative Medicine Kryptingos diferenciacijos būdas, skirtas ragenos endotelio ląstelių gamybai
JP6525962B2 (ja) 2013-05-03 2019-06-05 エメトロープ オフサルミクス エルエルシー ヒト角膜内皮細胞（ｈｃｅｃ）の同定及び分離
US10908161B2 (en) 2013-07-30 2021-02-02 Kyoto Prefectural Public University Corporation Corneal endothelial cell marker

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021112206A (ja) * 2013-05-03 2021-08-05 エメトロープ オフサルミクス エルエルシー ヒト角膜内皮細胞（ｈｃｅｃ）の同定及び分離

Also Published As

Publication number Publication date
EP3985102A1 (en) 2022-04-20
US20240027446A1 (en) 2024-01-25
WO2014179716A3 (en) 2015-01-22
US20160102290A1 (en) 2016-04-14
US10655102B2 (en) 2020-05-19
EP2992087A2 (en) 2016-03-09
EP3985102C0 (en) 2025-10-15
JP6877483B2 (ja) 2021-05-26
EP3985102B1 (en) 2025-10-15
JP2019150039A (ja) 2019-09-12
EP2992087A4 (en) 2016-09-21
EP2992087B1 (en) 2020-12-30
JP2016521130A (ja) 2016-07-21
JP2021112206A (ja) 2021-08-05
ES2853351T3 (es) 2021-09-15
JP2023116581A (ja) 2023-08-22
WO2014179716A2 (en) 2014-11-06
US20200277572A1 (en) 2020-09-03
JP7752485B2 (ja) 2025-10-10
US11740239B2 (en) 2023-08-29

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