JP6513949B2 - Ｖｄｊ組み換え産物を特定する方法 - Google Patents

Ｖｄｊ組み換え産物を特定する方法 Download PDF

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JP6513949B2
JP6513949B2 JP2014559299A JP2014559299A JP6513949B2 JP 6513949 B2 JP6513949 B2 JP 6513949B2 JP 2014559299 A JP2014559299 A JP 2014559299A JP 2014559299 A JP2014559299 A JP 2014559299A JP 6513949 B2 JP6513949 B2 JP 6513949B2
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vdj
cell population
recombinant
product
dna
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Japanese (ja)
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JP2015509724A5 (https=
JP2015509724A (ja
Inventor
ウッド アンドリュー
ウッド アンドリュー
ボルランド ダニエル
ボルランド ダニエル
マトヘソン ロウイセ
マトヘソン ロウイセ
コルコラン アンネ
コルコラン アンネ
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ザ・バブラハム・インスティテュート
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
JP2014559299A 2012-03-02 2013-03-01 Ｖｄｊ組み換え産物を特定する方法 Expired - Fee Related JP6513949B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1203720.6A GB201203720D0 (en) 2012-03-02 2012-03-02 Method of identifying VDJ recombination products
GB1203720.6 2012-03-02
PCT/GB2013/050516 WO2013128204A1 (en) 2012-03-02 2013-03-01 Method of identifying vdj recombination products

Publications (3)

Publication Number Publication Date
JP2015509724A JP2015509724A (ja) 2015-04-02
JP2015509724A5 JP2015509724A5 (https=) 2016-04-14
JP6513949B2 true JP6513949B2 (ja) 2019-05-22

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JP2014559299A Expired - Fee Related JP6513949B2 (ja) 2012-03-02 2013-03-01 Ｖｄｊ組み換え産物を特定する方法

Country Status (5)

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US (1) US9797014B2 (https=)
EP (1) EP2820153B1 (https=)
JP (1) JP6513949B2 (https=)
GB (1) GB201203720D0 (https=)
WO (1) WO2013128204A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10227655B2 (en) 2013-10-29 2019-03-12 Region Syddanmark Method for analyzing body fluid samples
US12043856B2 (en) 2016-05-24 2024-07-23 The Translational Genomics Research Institute Molecular tagging methods and sequencing libraries
CN108699554B (zh) * 2016-05-27 2019-11-01 深圳市海普洛斯生物科技有限公司 一种适用于超微量dna测序的接头及其应用
CN110234772B (zh) 2017-01-31 2024-01-19 路德维格癌症研究所有限公司 增强的免疫细胞受体测序方法
US20200131564A1 (en) * 2017-07-07 2020-04-30 Board Of Regents, The University Of Texas System High-coverage and ultra-accurate immune repertoire sequencing using molecular identifiers
CN112204155A (zh) * 2017-10-10 2021-01-08 纪念斯隆-凯特林癌症中心 引物提取和克隆性检测的系统和方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2671356B1 (fr) * 1991-01-09 1993-04-30 Inst Nat Sante Rech Med Procede de description des repertoires d'anticorps (ab) et des recepteurs des cellules t (tcr) du systeme immunitaire d'un individu.
US6221600B1 (en) 1999-10-08 2001-04-24 Board Of Regents, The University Of Texas System Combinatorial oligonucleotide PCR: a method for rapid, global expression analysis
DE60334471D1 (de) 2002-10-11 2010-11-18 Univ Erasmus Primer für nukleinsäureamplifikation in pcr-basierten klonalitätsstudien
US8642513B2 (en) * 2005-09-15 2014-02-04 Crucell Holland B.V. Method for preparing immunoglobulin libraries
WO2008026927A2 (en) 2006-08-30 2008-03-06 Academisch Medisch Centrum Process for displaying t- and b-cell receptor repertoires
WO2011140433A2 (en) * 2010-05-07 2011-11-10 The Board Of Trustees Of The Leland Stanford Junior University Measurement and comparison of immune diversity by high-throughput sequencing
EP2625295B1 (en) * 2010-10-08 2019-03-13 President and Fellows of Harvard College High-throughput immune sequencing

Also Published As

Publication number Publication date
US9797014B2 (en) 2017-10-24
GB201203720D0 (en) 2012-04-18
US20150031042A1 (en) 2015-01-29
EP2820153A1 (en) 2015-01-07
JP2015509724A (ja) 2015-04-02
EP2820153B1 (en) 2018-12-05
WO2013128204A1 (en) 2013-09-06

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