JP6497017B2 - Hygroscopic packaging - Google Patents

Description

  The present invention relates to a hygroscopic package that absorbs moisture in the package.

  In a package that wraps a product that dislikes moisture such as a biosensor such as a blood glucose level measurement sensor (glucose sensor, enzyme electrode), a hygroscopic agent such as silica gel is filled together with the product in order to remove moisture inside. Is known (Patent Documents 1 and 2).

  However, filling such a hygroscopic agent has a problem in that the surface of the package is uneven, making it easier to break the bag. Further, there is a problem that even if the bag is not broken, the gas barrier layer provided in the laminated film constituting the package is damaged in order to prevent water vapor from entering. In addition, the filling of the hygroscopic agent causes unevenness, resulting in an increase in bulkiness of the package, a decrease in filling properties during packaging, and an increase in transportation costs.

Further, there is a problem that the moisture absorbent is crushed in the bag during transportation or storage, and the fragments and powder adhere to contents such as a blood glucose level measurement sensor and have an adverse effect.
Furthermore, there are problems that the number of steps for filling the hygroscopic agent is increased, the working efficiency is lowered, and the manufacturing cost is increased.

Japanese Patent No. 4138070 Japanese Patent No. 4422285

  An object of the present invention is to solve the above-mentioned problems, and to provide a hygroscopic package that does not need to be filled with a hygroscopic agent, has good workability, and exhibits a high hygroscopic effect.

  As a result of various studies, the inventors have obtained a package obtained by heat-sealing a peripheral portion of two gas barrier laminated films having at least a gas barrier layer and a heat seal layer by overlapping the heat seal layer surfaces. Then, it has been found that the hygroscopic package achieves the above object, wherein at least one heat seal layer of the two gas barrier laminate films is a hygroscopic heat seal layer. It was.

The present invention is characterized by the following points.
(1) A packaging body obtained by heat-sealing a peripheral portion of two gas barrier laminate films having at least a gas barrier layer and a heat seal layer by superimposing the heat seal layer surfaces, the gas barrier laminate film 2 The hygroscopic package according to claim 1, wherein at least one of the heat seal layers is a hygroscopic heat seal layer.
(2) The hygroscopic package according to (1), wherein the hygroscopic heat seal layer is made of a heat seal resin containing a hygroscopic agent.
(3) The hygroscopic package according to (2), wherein the hygroscopic agent is a chemical hygroscopic agent.
(4) The hygroscopic packaging body according to any one of (1) to (3), which is a packaging body for a blood glucose level measurement sensor.

In the hygroscopic package of the present invention, the innermost layer of the package exhibits hygroscopicity. Therefore, moisture inside the package can be absorbed quickly and efficiently, and deterioration of the product due to moisture can be prevented without filling the moisture absorbent.
Moreover, since it does not fill with a hygroscopic agent, it is difficult to break the bag during transportation or storage, and the contents can be stably stored over a long period of time without damaging the gas barrier layer.

  Furthermore, since there is no need to fill the hygroscopic agent, the work efficiency is good and the manufacturing cost can be reduced. Moreover, since a hygroscopic agent is not accommodated, it can be set as a thin package which is not bulky, and a transportation cost is also reduced.

  Therefore, the hygroscopic package of the present invention is a disposable enzyme electrode used for monitoring a blood glucose level by self-collecting blood when a diabetic patient administers insulin. Especially suitable.

It is a schematic sectional drawing which shows the example about the layer structure of the hygroscopic laminated | multilayer film which comprises the hygroscopic packaging body of this invention. It is a schematic sectional drawing which shows another example about the layer structure of the hygroscopic laminated | multilayer film which comprises the hygroscopic packaging body of this invention.

The above-described present invention will be described in more detail below.
<Layer structure of hygroscopic easily peelable package of the present invention>
FIG. 1 is a schematic cross-sectional view showing an example of the layer structure of the hygroscopic package according to the present invention. As shown in FIG. 1, the package of the present invention comprises two gas barrier laminate films (A, B) having a gas barrier layer (1, 4) and a heat seal layer (2, 3). The surfaces of the layers (2, 3) are overlapped with each other facing each other, and the peripheral edge is heat-sealed. Here, at least one (A) of the two gas barrier laminate films is a hygroscopic heat seal layer in which the heat seal layer (2) exhibits hygroscopicity. The hygroscopic or non-hygroscopic heat seal layer (2, 3) may be a single layer configuration or a multilayer configuration.

When the hygroscopic heat seal layer (2) has a single layer structure, the hygroscopic heat seal layer (2) is a layer made of a heat seal resin containing a hygroscopic agent.
When the heat-sealable layer (2) exhibiting hygroscopicity has a multilayer structure, the hygroscopic heat-seal layer (2) includes at least a layer composed of a resin composition containing a hygroscopic agent and a binder resin, and a heat-sealable resin. And a layer consisting of Here, the binder resin may be a heat-sealable resin, and the layer made of the heat-sealable resin may contain a hygroscopic agent.

  For example, when the hygroscopic heat seal layer (2) has a two-layer structure, one of the two layers, for example, the innermost layer of the package is made of a heat sealable resin containing a hygroscopic agent. The layer opposite to the other gas barrier layer may be made of a heat-sealable resin that does not contain a hygroscopic agent. Since the layer on the side facing the gas barrier layer does not contain a hygroscopic agent, the adhesive strength between the layers can be increased. Conversely, the innermost layer of the package is made of a heat-sealable resin containing no hygroscopic agent, and the layer facing the gas barrier layer is made of a heat-sealable resin containing a hygroscopic agent. Also good. With this configuration, the sealing strength of the package can be improved.

  In another embodiment, the hygroscopic heat seal layer (2) may have a three-layer structure as shown in FIG. In this case, for example, heat-sealable resin layer (2a) containing no hygroscopic agent / intermediate layer (2b) made of a resin composition containing a hygroscopic agent and a binder resin / heat-sealable resin layer containing no hygroscopic agent (2c) ) Is preferable because the sealing strength and interlayer adhesion strength can be improved.

<Gas barrier layer>
In this invention, a gas barrier layer (1, 4) is not specifically limited, You may consist of a gas barrier film which has the barrier property with respect to well-known or commercially available oxygen gas or water vapor | steam.

  Specific examples of the gas barrier film suitably used in the present invention include resins such as polyethylene terephthalate (PET), polybutylene terephthalate, polyethylene naphthalate, polyamide, polyimide, polyvinyl alcohol, and ethylene / vinyl alcohol copolymer. The resin film which becomes can be mentioned.

  Further, any base film such as polyethylene resin, polypropylene resin, cyclic polyolefin resin, fluorine resin, polystyrene resin, acrylonitrile-styrene copolymer (AS resin), acrylonitrile-butadiene-styrene copolymer ( ABS resin), polyvinyl chloride resin, fluorine resin, poly (meth) acrylic resin, polycarbonate resin, polyester resins such as PET and polyethylene naphthalate, polyamide resins such as various nylons, polyimide resins, From various resins such as polyamideimide resin, polyaryl phthalate resin, silicone resin, polysulfone resin, polyphenylene sulfide resin, polyethersulfone resin, polyurethane resin, acetal resin, cellulose resin, etc. Deposited film having a vapor deposited film such as a silica-deposited film or alumina-deposited film may be mentioned on at least one side of that film.

Furthermore, although the laminated film which laminated metal foil, such as aluminum foil, on the said base film can also be used, it is not limited to these.
Among the above-mentioned films, it is preferable to use a silica vapor-deposited film, an alumina vapor-deposited film, a laminated film laminated with an aluminum foil, or the like from the viewpoint of excellent gas barrier properties. In particular, by using an aluminum foil, light shielding properties can be imparted, and as a result, it can be suitably used as a package for products that are easily deteriorated by light irradiation.

Moreover, in one of the preferable aspects, at least one of the two gas barrier laminate films constituting the package of the present invention has visibility.
More preferably, the non-transparent hygroscopic gas barrier laminate in which one of the two gas barrier multi-layer films constituting the package has a non-transparent gas barrier layer (1) and a hygroscopic heat seal layer (2). It is a film (A), and the other sheet is a transparent non-hygroscopic gas barrier laminate film (B) having a transparent gas barrier layer (4) and a non-hygroscopic heat seal layer (3).

With this configuration, it can be particularly preferably used as a package of a product that preferably confirms the internal state and the direction of contents from the outside of the package before opening, for example, a package of a blood glucose level measurement sensor.
As a transparent gas barrier layer, it is preferable to use a silica vapor deposition film, for example, For example, IB-PET-RB (made by Dai Nippon Printing Co., Ltd.) can be used suitably.
Furthermore, you may provide the gas barrier coating film which is demonstrated below on the said vapor deposition film. Thereby, a further excellent gas barrier property can be obtained.

  In the present invention, the gas barrier coating film is a gas barrier property obtained by hydrolysis and polycondensation of an alkoxide and a water-soluble polymer by the sol-gel method in the presence of a sol-gel method catalyst, acid, water and an organic solvent. It is a film formed by applying and drying the composition. In some cases, the gas barrier composition may further contain a silane coupling agent.

Examples of the alkoxide that can be used in the gas barrier composition include a general formula R ¹ _n M (OR ² ) _m (wherein R ¹ and R ² represent an organic group having 1 to 8 carbon atoms, M Represents a metal atom, n represents an integer of 0 or more, m represents an integer of 1 or more, and n + m represents an atomic valence of M), and preferably at least one alkoxide represented by Can be used. Here, as the metal atom M, silicon, zirconium, titanium, aluminum or the like can be used. Specific examples of the organic group represented by R ¹ and R ² include alkyl groups such as a methyl group, an ethyl group, an n-propyl group, an i-propyl group, an n-butyl group, and an i-butyl group. Can be mentioned. In the same molecule, these alkyl groups may be the same or different. Examples of such alkoxides include tetramethoxysilane Si (OCH ₃ ) ₄ , tetraethoxysilane Si (OC ₂ H ₅ ) ₄ , tetrapropoxysilane Si (OC ₃ H ₇ ) ₄ , tetrabutoxysilane Si (OC _4). H ₉ ) _{4 and the} like.

  As the water-soluble polymer that can be used in the gas barrier composition, either a polyvinyl alcohol-based resin or an ethylene / vinyl alcohol copolymer or both can be preferably used.

  The sol-gel catalyst can be a tertiary amine, particularly N, N-dimethylbenzylamine, which is substantially insoluble in water and soluble in an organic solvent. Examples of the acid used in the gas barrier composition include mineral acids such as sulfuric acid, hydrochloric acid, and nitric acid, and organic acids such as acetic acid and tartaric acid. Furthermore, as the organic solvent, for example, methyl alcohol, ethyl alcohol, isopropyl alcohol, n-propyl alcohol, or the like can be used.

  The content of the water-soluble polymer in the gas barrier composition is preferably in the range of 5 to 500 parts by weight with respect to 100 parts by weight of the total amount of the alkoxide. In the above, if it exceeds 500 parts by weight, the formed gas barrier coating film becomes more brittle and its weather resistance and the like are also unfavorable.

When the gas barrier composition is applied onto the vapor deposition film and heated to remove the solvent and the alcohol produced by the polycondensation reaction, the polycondensation reaction is completed, and a transparent gas barrier coating film is formed. Here, since the hydroxyl group generated by hydrolysis and the silanol group derived from the silane coupling agent are bonded to the hydroxyl group on the surface of the deposited film, the adhesiveness between the deposited film and the gas barrier coating film is good. Become.
The gas barrier coating film may be a composite polymer layer in which one layer or two or more layers are laminated. Moreover, the dry film thickness may be 0.01-30 micrometers, Preferably the thickness may be 0.1-10 micrometers.

<Heat seal layer>
One of the two gas barrier laminate films constituting the package of the present invention is a hygroscopic heat seal layer in which the heat seal layer exhibits hygroscopicity, and the other heat seal layer is hygroscopic. Or non-hygroscopic.

  When applied to a package of a product for which it is preferable to confirm the state of the inside and the direction of the contents from the outside of the package, such as a package for a blood glucose level sensor, the other heat seal layer is not It is preferably hygroscopic and exhibits high transparency.

Hygroscopic heat seal layer In the present invention, the hygroscopic agent contained in the hygroscopic heat seal layer is not particularly limited, and a known or commercially available material having an absolutely dry effect or a humidity control effect can be used. The absolute dry effect indicates the effect of absorbing relative humidity up to about 0%, and the humidity control effect is the effect of absorbing moisture when the humidity is high and releasing moisture when the humidity is low, thereby keeping the humidity constant. Point to.

  In the present invention, those suitably used as the hygroscopic agent include, for example, silica gel, alumina gel, silica alumina gel, anhydrous magnesium sulfate, zeolite, synthetic zeolite, calcium oxide, calcium chloride, and calcined alum, or a mixture thereof. However, it is not limited to these.

  When used as a package for a blood glucose level measurement sensor, it is possible to prevent the re-release of moisture that has been absorbed once, and because it is stable over time in the low humidity state of the package, etc. A chemical hygroscopic agent having an effect is preferred. And by using the chemical hygroscopic agent which has an absolutely dry effect, as shown in Table 1, the humidity in the pouch bag can maintain a low value even after elapse of 7 days, for example.

  Further, by using the chemical hygroscopic agent, the amount of addition can be reduced as compared with the case of using a physical hygroscopic agent, and in some cases, the hygroscopic heat seal layer can also be configured as a single layer.

In the present invention, the binder resin mixed with the hygroscopic agent is not particularly limited as long as the hygroscopic agent can be stably held, and any resin can be used. In particular, a heat sealable resin can be preferably used.
It does not restrict | limit especially as heat sealable resin, The well-known or commercially available polyolefin resin which has heat sealability can be used.

  Examples of such polyolefin-based resins include low-density polyethylene, medium-density polyethylene, high-density polyethylene, linear (linear) low-density polyethylene (LLDPE), and the like, polypropylene, ethylene-vinyl acetate copolymer, ethylene- Ethyl acrylate copolymer, ethylene-acrylic acid copolymer, ethylene-methacrylic acid copolymer, ethylene-methyl methacrylic acid copolymer, ethylene-propylene copolymer, methylpentene polymer, acid-modified polyolefin resin, and Although the mixture of these resin etc. are mentioned, it is not limited to these resins. In addition, any of an antioxidant, an anti-blocking agent and the like that is present in a small amount as an additive can also be applied.

In particular, it is preferable to use low density polyethylene, LLDPE, polypropylene or the like in order to exhibit excellent heat sealability and hygroscopicity in a state containing a hygroscopic agent.
The amount of the hygroscopic agent added to the hygroscopic heat seal layer may be 1% by mass or more based on the total mass of the hygroscopic heat seal layer to which the hygroscopic agent is added, that is, the total mass of the hygroscopic additive layer. However, in order to obtain a good hygroscopic effect, the content is preferably 3% by mass or more. On the other hand, in order to obtain good film forming properties, the amount of the hygroscopic agent needs to be less than 55% by mass.

  The amount of the hygroscopic agent added is 1% by mass to 50% by mass, preferably 3% by mass to 50% by mass, and more preferably 15% by mass to 50% by mass with respect to the total mass of the hygroscopic agent added layer of the hygroscopic heat seal layer. % By mass.

  In another embodiment, the hygroscopic heat seal layer may be a layer made of hygroscopic resin such as nylon or ethylene-vinyl acetate copolymer. Furthermore, the addition amount of the hygroscopic agent in the hygroscopic resin is 1% by mass to 50% by mass, preferably 3% by mass to 50% by mass, and more preferably based on the total mass of the hygroscopic heat seal layer. It is 15 mass%-50 mass%.

As the thickness of the hygroscopic heat seal layer, film formation is possible if it is 5 μm or more, but preferably 10 μm to 200 μm in order to obtain good film forming property and hygroscopicity.
In one embodiment of the present invention, the adsorptive heat seal layer has a single-layer structure made of a resin composition obtained by kneading a hygroscopic agent in a heat sealable resin.

  In another embodiment, the hygroscopic heat seal layer has a multilayer structure having two or more layers, and each layer may be made of a resin composition in which the amount of the hygroscopic agent is different. In this configuration, there may be a layer made of only a heat-sealable resin without containing a hygroscopic agent.

  The hygroscopic agent may be uniformly dispersed in the layer. Further, for example, it may be dispersed with an increasing concentration gradient from the surface on the innermost layer side to the surface facing the gas barrier layer, and this configuration improves heat sealability. On the contrary, it may be dispersed with a decreasing concentration gradient from the surface on the innermost layer side to the surface facing the gas barrier layer, and this configuration improves interlayer adhesion strength.

  For example, in a hygroscopic package comprising an LDPE layer / hygroscopic heat seal layer (1) / hygroscopic heat seal layer (2), the hygroscopic heat seal layer (1) is more hygroscopic than the hygroscopic agent added. It can be appropriately selected depending on the use to make it larger than the heat-resistant heat seal layer (2) or vice versa.

  As a method of kneading the hygroscopic agent in the heat-sealable resin or binder resin, a known or conventional kneading method can be applied. For example, a so-called masterbatch-type blending method in which a moisture-absorbing agent is dispersed in a heat-sealable resin or a binder resin to produce a pellet-like masterbatch, which is dispersed again in the heat-sealable resin or binder resin. Even a hygroscopic agent that easily aggregates can be uniformly dispersed.

Non-Hygroscopic Heat Seal Layer In the present invention, when one heat seal layer of the two gas barrier laminated films constituting the package is a non-hygroscopic heat seal layer that does not exhibit hygroscopicity, this layer is The constituent resin is not particularly limited as long as it has heat sealability, and a known or commercially available polyolefin resin having heat sealability can be used. For example, polyethylene such as low density polyethylene, medium density polyethylene, high density polyethylene, linear (linear) low density polyethylene, 1-butene, 1-pentene, 1-hexene, 1-octene, polypropylene, propylene elastomer, ethylene -Vinyl acetate copolymer, ethylene-ethyl acrylate copolymer, ethylene-acrylic acid copolymer, ethylene-methacrylic acid copolymer, ethylene-methyl methacrylic acid copolymer, ethylene-propylene copolymer, methylpentene Polymers, acid-modified polyolefin resins, and the like can be used, and are not limited to these resins.

<Laminated film>
By laminating the heat seal layer on the gas barrier film constituting the gas barrier layer, the gas barrier laminated film constituting the package of the present invention is obtained.
In the present invention, this laminating method is not particularly limited, and the resin or resin composition forming the heat seal layer may be laminated by extrusion coating on a gas barrier film, optionally via an adhesive layer. it can. In extrusion coating, first, the resin or resin composition is heated and melted, expanded and stretched in a necessary width direction with a T-die, extruded into a curtain shape, and the molten resin is allowed to flow down onto a gas barrier film. By sandwiching between a rubber roll and a cooled metal roll, the heat seal layer is formed and adhered to the gas barrier film and laminated at the same time.

  Here, the adhesive layer may be made of an arbitrary anchor coating agent, and for example, an organic titanium-based, isocyanate-based, polyethyleneimine-based, acid-modified polyethylene-based, polybutadiene-based anchor coating agent or the like can be used.

  Alternatively, a film made of the above resin or resin composition may be formed, and this may be laminated with a gas barrier film via an adhesive layer by dry lamination, non-solvent lamination, sand lamination, or the like. Here, as a film forming method, a known or conventional film forming method can be applied. For example, when an inflation method is used as the film forming method, a heat-sealable resin or binder that forms a heat seal layer. The melt flow rate (MFR) of the resin is preferably 0.2 to 5.0 g / 10 min, and more preferably 0.2 to 4.0 g / 10 min. If the MFR is less than 0.2 g / 10 min or 5.0 g / 10 min or more, it is not effective in terms of proper processing. In addition, in this specification, MFR is a value measured from the method based on JISK7210.

In one embodiment of the present invention, the adhesive layer may be a layer made of an adhesive for dry laminate, an adhesive for non-solvent laminate, or the like.
When using an adhesive for dry laminating as an adhesive layer, the adhesive dispersed or dissolved in a solvent is applied onto one film and dried, and the other film is stacked and laminated at a temperature of 30 to 120 ° C. By aging from time to several days, the adhesive is cured and laminated.

  When using an adhesive for non-solvent laminating, the adhesive itself is applied on a film without being dispersed or dissolved in a solvent and dried, and the other film is laminated and laminated, and then at 30 to 120 ° C. for several hours. Aged for several days to cure and laminate the adhesive.

  These adhesives may be thermosetting, ultraviolet curable, electron beam curable, or the like. Examples of such adhesives include polyvinyl acetate adhesives such as polyvinyl acetate and vinyl acetate-ethylene copolymers, and polyacrylic acid composed of copolymers of polyacrylic acid and polystyrene, polyester, polyvinyl acetate, and the like. Adhesives, cyanoacrylate adhesives, ethylene copolymer adhesives made of copolymers of ethylene and monomers such as vinyl acetate, ethyl acrylate, acrylic acid, methacrylic acid, cellulose adhesives, polyurethane adhesives Polyester adhesive, polyamide adhesive, polyimide adhesive, polyolefin adhesive, amino resin adhesive made of urea resin or melamine resin, phenol resin adhesive, epoxy adhesive, reactive type (meta ) Acrylic adhesives, chloroprene rubber, nitrile rubber, styrene-butadiene rubber, etc. Ranaru elastomeric adhesive, a silicone adhesive, an alkali metal silicate, inorganic adhesive or the like made of a low-melting glass.

  In addition, the adhesive may be in any form such as aqueous type, solution type, emulsion type, dispersion type, and the property may be any form such as film / sheet shape, powder shape, solid shape, Further, the bonding mechanism may be any form such as a chemical reaction type, a solvent volatilization type, a heat melting type, and a hot pressure type.

The adhesive layer is formed by applying the above-mentioned adhesive by, for example, roll coating, gravure roll coating, kiss coating, etc., and the coating amount is preferably about 0.1 to 10 g / m ² (dry state). By setting the coating amount of the adhesive within the above range, good adhesiveness can be obtained.

In another embodiment of the present invention, the gas barrier film and the film forming the heat seal layer may be laminated by sand lamination. In this case, any resin that can be heated and melted and applied by an extruder can be used for the adhesive layer. Specifically, the resins mentioned as the heat sealable resin can be preferably used.
In the present invention, the gas barrier laminate film may have a further layer in addition to the gas barrier layer and the heat seal layer.

<Packaging body>
The package of the present invention is formed by bag-making the above gas barrier laminate film, and the two laminate films are overlapped so that the surfaces of the heat seal layer face each other, and the peripheral portion thereof is heat sealed. Can be manufactured.

  In the present invention, publicly known methods such as a bar seal, a rotary roll seal, a belt seal, an impulse seal, a high frequency seal, and an ultrasonic seal can be applied as a heat seal method.

<Example 1>
A hygroscopic resin composition containing 35% by mass of calcium oxide in a polyethylene resin (Daiichi Seika Kogyo Co., Ltd., Pericon) and LLDPE (Prime Polymer Co., Ltd., ULTZEX 2022F) are subjected to an inflation method (extrusion temperature). 180 ° C.) to produce a hygroscopic heat-sealable resin film of LLDPE layer 10 μm / hygroscopic resin composition layer (calcium oxide 35 mass%) 60 μm / LLDPE layer 10 μm.

PET film (thickness 12 μm, Toyobo Co., Ltd., S4102 made), aluminum foil (thickness 9 μm, made by Toyo Aluminum Co., Ltd.), and dry laminate adhesive (lock paint) Co., RU004 / H-1, coating amount 3.5 g / m ^{2 for} each adhesive layer, drying temperature 70 ° C.), PET film / adhesive / aluminum foil / adhesive / hygroscopic heat seal A hygroscopic gas barrier laminate film having a layer structure of a conductive resin film was produced.

On the other hand, PET film (thickness 12 μm, manufactured by Toyobo Co., Ltd., ESPET T4102), aluminum foil (thickness 9 μm, Toyo Aluminum Co., Ltd.), and LLDPE film (Toyobo Co., Ltd., Rick Film L6100) were dried. Lamination adhesive (Rock Paint Co., Ltd., RU004 / H-1, coating amount 3.5 g / m ^{2 for} each adhesive layer, drying temperature 70 ° C.) and bonding, PET film / adhesive / aluminum foil / A gas barrier laminate film having a hygroscopicity having an adhesive / LLDPE film layer structure was produced.

The hygroscopic gas barrier laminate film obtained above and the gas barrier laminate film not having hygroscopic properties are overlapped with the surface of the hygroscopic heat-sealable resin film facing the surface of the LLDPE film, and its peripheral edge Was heat-sealed under the conditions of 160 ° C., 1 kgf / cm ² , and 1 second to produce a hygroscopic package of the present invention.

<Example 2>
Except for using a hygroscopic heat-sealable resin film (Sasaki Chemical Co., Ltd., Dry Keep ^(R) SPES30-132J) as the hygroscopic heat-sealable resin film, the same as in Example 1 was used. A hygroscopic package was produced.

<Example 3>
As a gas barrier layer in a gas barrier laminate film having no hygroscopicity, silicon oxide is formed on a PET film (thickness 12 μm) by chemical vapor deposition instead of a gas barrier film obtained by laminating an aluminum foil on a PET film. A gas barrier film (Dai Nippon Printing Co., Ltd., IB-PET-RB) provided with a vapor deposition film (thickness 10 nm) and a gas barrier coating film (thickness 200 nm) is applied. A hygroscopic package of the present invention was produced in the same manner as in Example 1 except that a gas barrier laminate film having a layer configuration of vapor deposition film / PET film / adhesive / LLDPE film was used.

<Example 4>
As a gas barrier layer in a hygroscopic gas barrier laminated film and a gas barrier laminated film having no hygroscopic property, a chemical film is formed on a PET film (thickness 12 μm) instead of a gas barrier film formed by laminating an aluminum foil on a PET film. A gas barrier film (Dai Nippon Printing Co., Ltd., IB-PET-RB) provided with a silicon oxide vapor deposition film (thickness 10 nm) by a vapor deposition method and a gas barrier coating film (thickness 200 nm) is applied. Gas barrier coating film / deposition film / PET film / adhesive / hygroscopic heat-sealable resin film, and laminated film having a gas barrier coating film / deposition film / PET film / adhesive / LLDPE film. A hygroscopic package of the present invention was produced in the same manner as in Example 1 except that it was used.

<Example 5>
The hygroscopic heat-sealable resin film produced in Example 1 was laminated between an aluminum foil of a gas barrier laminate film having no hygroscopic property and an LLDPE film via an adhesive for dry lamination, and PET film / adhesion The hygroscopic package of the present invention was prepared in the same manner as in Example 1 except that a laminated film having a layer structure of agent / aluminum foil / adhesive / hygroscopic heat-sealable resin film / adhesive / LLDPE film was produced. Manufactured.

<Example 6>
The hygroscopic heat-sealable resin film produced in Example 1 is laminated between the PET film and the LLDPE film, which are non-hygroscopic PET films, via an adhesive for dry lamination, and a gas barrier coating film / deposition is deposited. A hygroscopic package of the present invention was produced in the same manner as in Example 4 except that a laminated film having a layer configuration of film / PET film / adhesive / hygroscopic heat-sealable resin film / LLDPE film was produced.

<Example 7>
A hygroscopic package of the present invention was produced in the same manner as in Example 1 except that a hygroscopic heat-sealable resin film (Sasaki Chemical Co., Ltd., Dry Keep ^(R) SPES30-111J) was used.

<Example 8>
PET film / adhesive / aluminum foil / adhesive / hygroscopicity was used in the same manner as in Example 1 using two hygroscopic heat-sealable resin films (Sasaki Chemical Co., Ltd., Dry Keep ^(R) SPES30-132J). Two heat-sealable resin films were prepared, the surfaces of the hygroscopic heat-seal layer were opposed to each other, and the peripheral edges were heat-sealed under the conditions of 160 ° C., 1 kgf / cm ² , 1 second, A hygroscopic package of the present invention was produced.

<Example 9>
Hygroscopic resin composition containing 50% by mass of calcium oxide in polyethylene resin (Pericon: Dainichi Seika Kogyo Co., Ltd.), LLDPE (Prime Polymer Co., Ltd., ULTZEX)
2022F) by co-extrusion by an inflation method (extrusion temperature 180 ° C.), and a hygroscopic heat-sealable resin film of LLDPE layer 10 μm / hygroscopic resin composition layer (calcium oxide 50 mass%) 30 μm / LLDPE layer 10 μm A hygroscopic package of the present invention was produced in the same manner as in Example 1 except that was produced.

<Example 10>
Hygroscopic resin composition containing 15% by mass of calcium oxide in polyethylene resin (Daiichi Seika Kogyo Co., Ltd., Pericon) and LLDPE (Prime Polymer Co., Ltd., ULTZEX)
2022F) and a coextruded film by an inflation method (extrusion temperature 180 ° C.), and a hygroscopic heat-sealable resin film of LLDPE layer 10 μm / hygroscopic resin composition layer (calcium oxide 15% by mass) 30 μm / LLDPE layer 10 μm A hygroscopic package of the present invention was produced in the same manner as in Example 1 except that was produced.

<Example 11>
Hygroscopic resin composition containing 35% by mass of calcium oxide in polyethylene resin (Daiichi Seika Kogyo Co., Ltd., Pericon), LLDPE (Prime Polymer Co., Ltd., ULTZEX)
2022F) by co-extrusion by an inflation method (extrusion temperature 180 ° C.), and a hygroscopic heat-sealable resin film of LLDPE layer 10 μm / hygroscopic resin composition layer (calcium oxide 35 mass%) 30 μm / LLDPE layer 10 μm A hygroscopic package of the present invention was produced in the same manner as in Example 1 except that was produced.

<Example 12>
Except that a hygroscopic heat-sealable resin film (Sasaki Chemical Co., Ltd., Drykeep ^(R) SPES30-132J) was used as the hygroscopic heat-sealable resin film, A hygroscopic package was produced.

<Comparative Example 1>
Instead of laminating a hygroscopic heat-sealable resin film, LLDPE (Prime Polymer Co., Ltd., ULTZEX) does not contain a hygroscopic agent.
2022F) A laminated film and a package were produced in the same manner as in Example 1 except that a heat seal layer (thickness 50 μm) was provided.

<Hygroscopic effect>
A pouch bag (120 mm × 160 mm) was prepared from the laminated films prepared in Examples and Comparative Examples, a hygrometer was placed in the pouch, and the relative humidity after being left for 7 days was measured. The evaluation results are shown in Table 1.

本結果より、実施例１〜１２の包装体は、良好な吸湿効果を示した。

From this result, the packaging body of Examples 1-12 showed the favorable hygroscopic effect.

A, B Gas barrier laminated film 1, 4 Gas barrier layer 2, 3 Heat seal layer 2a, 2c Heat seal resin layer 2b containing no hygroscopic agent Intermediate layer

Claims (2)

A package obtained by heat-sealing a peripheral portion of two gas barrier laminate films having at least a gas barrier layer and a heat seal layer, by superimposing the heat seal layer surface,
Of the two gas barrier laminate films that make up the package,
One sheet is a non-transparent hygroscopic gas barrier laminated film having a non-transparent gas barrier layer and a hygroscopic heat seal layer,
The other is a transparent non-hygroscopic gas barrier laminated film having a transparent gas barrier layer and a non-hygroscopic heat seal layer,
The non-transparent hygroscopic gas barrier laminate film heat seal layer is a hygroscopic heat seal layer made of a heat seal resin containing a chemical hygroscopic agent,
The hygroscopic heat seal layer has a two-layer structure, the inner layer of the package is made of a heat seal resin containing a hygroscopic agent, and the layer on the side facing the other gas barrier layer is It consists of a heat-sealable resin that does not contain a hygroscopic agent.
The hygroscopic package described above.   The hygroscopic packaging body according to claim 1, which is a packaging body for a blood glucose level measurement sensor.

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