JP6420233B2 - 末梢神経損傷を処置するためのニューレグリンの使用 - Google Patents

末梢神経損傷を処置するためのニューレグリンの使用 Download PDF

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JP6420233B2
JP6420233B2 JP2015503646A JP2015503646A JP6420233B2 JP 6420233 B2 JP6420233 B2 JP 6420233B2 JP 2015503646 A JP2015503646 A JP 2015503646A JP 2015503646 A JP2015503646 A JP 2015503646A JP 6420233 B2 JP6420233 B2 JP 6420233B2
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composition
weeks
body weight
neuregulin
injury
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JP2015514096A5 (https=
JP2015514096A (ja
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アンソニー オー. カッジャーノ
アンソニー オー. カッジャーノ
アンソニー ジェイ. ベラ
アンソニー ジェイ. ベラ
アニンディータ ガングリー
アニンディータ ガングリー
ジェニファー イアチ
ジェニファー イアチ
トーマス パリー
トーマス パリー
レイモンド ワレン コルバーン
レイモンド ワレン コルバーン
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アコーダ セラピューティクス,インコーポレーテッド
アコーダ セラピューティクス,インコーポレーテッド
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1883Neuregulins, e.g.. p185erbB2 ligands, glial growth factor, heregulin, ARIA, neu differentiation factor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
JP2015503646A 2012-03-30 2013-03-29 末梢神経損傷を処置するためのニューレグリンの使用 Expired - Fee Related JP6420233B2 (ja)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US201261618381P 2012-03-30 2012-03-30
US61/618,381 2012-03-30
US201261674060P 2012-07-20 2012-07-20
US61/674,060 2012-07-20
US201261693589P 2012-08-27 2012-08-27
US201261693585P 2012-08-27 2012-08-27
US61/693,585 2012-08-27
US61/693,589 2012-08-27
US201361785419P 2013-03-14 2013-03-14
US61/785,419 2013-03-14
PCT/US2013/034634 WO2013149163A1 (en) 2012-03-30 2013-03-29 Use of neuregulin to treat peripheral nerve injury

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2017076415A Division JP2017149746A (ja) 2012-03-30 2017-04-07 末梢神経損傷を処置するためのニューレグリンの使用

Publications (3)

Publication Number Publication Date
JP2015514096A JP2015514096A (ja) 2015-05-18
JP2015514096A5 JP2015514096A5 (https=) 2015-08-06
JP6420233B2 true JP6420233B2 (ja) 2018-11-07

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Family Applications (4)

Application Number Title Priority Date Filing Date
JP2015503646A Expired - Fee Related JP6420233B2 (ja) 2012-03-30 2013-03-29 末梢神経損傷を処置するためのニューレグリンの使用
JP2017076415A Pending JP2017149746A (ja) 2012-03-30 2017-04-07 末梢神経損傷を処置するためのニューレグリンの使用
JP2019070976A Pending JP2019131582A (ja) 2012-03-30 2019-04-03 末梢神経損傷を処置するためのニューレグリンの使用
JP2021004728A Expired - Fee Related JP7108724B2 (ja) 2012-03-30 2021-01-15 末梢神経損傷を処置するためのニューレグリンの使用

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JP2017076415A Pending JP2017149746A (ja) 2012-03-30 2017-04-07 末梢神経損傷を処置するためのニューレグリンの使用
JP2019070976A Pending JP2019131582A (ja) 2012-03-30 2019-04-03 末梢神経損傷を処置するためのニューレグリンの使用
JP2021004728A Expired - Fee Related JP7108724B2 (ja) 2012-03-30 2021-01-15 末梢神経損傷を処置するためのニューレグリンの使用

Country Status (15)

Country Link
US (3) US20150094263A1 (https=)
EP (3) EP3842059A1 (https=)
JP (4) JP6420233B2 (https=)
CN (2) CN104321072A (https=)
AU (4) AU2013237896B2 (https=)
BR (1) BR112014024308B1 (https=)
CA (1) CA2869070A1 (https=)
DK (2) DK3278811T3 (https=)
ES (2) ES2647917T3 (https=)
IL (3) IL288785B2 (https=)
MX (1) MX354598B (https=)
NZ (1) NZ700546A (https=)
PL (2) PL2830645T3 (https=)
PT (2) PT2830645T (https=)
WO (1) WO2013149163A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110166068A1 (en) 2008-07-17 2011-07-07 Acorda Therapeutics, Inc. Therapeutic Dosing of a Neuregulin or a Subsequence Thereof for Treatment or Pro-phylaxis of Heart Failure
NZ625673A (en) 2009-10-14 2015-11-27 Acorda Therapeutics Inc Use of a neuregulin to treat peripheral nerve injury
ITUB20155471A1 (it) * 2015-11-11 2017-05-11 Univ Degli Studi Di Torino Coniugato della neuregulina 1 per il trattamento delle lesioni dei nervi periferici
WO2017096358A1 (en) * 2015-12-04 2017-06-08 University Of Iowa Research Foundation Apparatus, systems and methods for predicting, screening and monitoring of encephalopathy / delirium
US11511136B2 (en) 2017-11-17 2022-11-29 The Research Foundation For The State University Of New York Method for treating damaged peripheral nerves using x-ray microbeam irradiation
CN110946991A (zh) * 2018-09-27 2020-04-03 广州中医药大学(广州中医药研究院) 神经调节蛋白1的应用
WO2021022254A2 (en) * 2019-08-01 2021-02-04 Mark Evans Methods and apparatus for reducing the risk, and identifying the existence, of neurological injury to a human fetus during and before labor
CN116116737B (zh) * 2023-04-14 2023-06-30 新华手术器械有限公司 止血钳毛坯自动上料装置及使用方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7037A (en) 1850-01-22 Grid-ikon slide-valve
US888A (en) 1838-08-20 perkins
US5530109A (en) 1991-04-10 1996-06-25 Ludwig Institute For Cancer Research DNA encoding glial mitogenic factors
US5716930A (en) 1991-04-10 1998-02-10 Ludwig Institute For Cancer Research Glial growth factors
US6087323A (en) * 1992-04-03 2000-07-11 Cambridge Neuroscience, Inc. Use of neuregulins as modulators of cellular communication
US7037888B1 (en) 1992-04-03 2006-05-02 Acorda Therapeutics, Inc. Methods for treating muscle diseases and disorders
AU745324B2 (en) * 1997-10-14 2002-03-21 Cenes Pharmaceuticals, Inc. Therapeutic methods comprising use of a neuregulin
AU2001274947B2 (en) * 2000-05-23 2006-08-17 Acorda Therapeutics, Inc. Nrg-2 nucleic acid molecules, polypeptides, and diagnostic and therapeutic methods
US20100286043A1 (en) * 2007-10-05 2010-11-11 Tufts Medical Center, Inc. Use of neuregulin-1 in reducing brain damage
WO2009108390A2 (en) * 2008-02-29 2009-09-03 Acorda Therapeutics, Inc. Method for achieving desired glial growth factor 2 plasma levels
US20110166068A1 (en) * 2008-07-17 2011-07-07 Acorda Therapeutics, Inc. Therapeutic Dosing of a Neuregulin or a Subsequence Thereof for Treatment or Pro-phylaxis of Heart Failure
KR101237927B1 (ko) * 2009-05-07 2013-03-04 (주)문엔제이 신경손상 및 신경질환 예방 또는 치료용 약학조성물
NZ625673A (en) * 2009-10-14 2015-11-27 Acorda Therapeutics Inc Use of a neuregulin to treat peripheral nerve injury
EP2603221A4 (en) * 2010-08-13 2014-02-26 Univ Georgetown GGF2 AND METHOD FOR ITS APPLICATION

Also Published As

Publication number Publication date
NZ700546A (en) 2017-05-26
IL273186A (en) 2020-04-30
IL234882B (en) 2020-03-31
PT3278811T (pt) 2021-03-03
US20150094263A1 (en) 2015-04-02
IL288785B (en) 2022-11-01
AU2013237896A1 (en) 2014-10-16
ES2647917T3 (es) 2017-12-27
IL288785A (en) 2022-02-01
JP2021059605A (ja) 2021-04-15
ES2857810T3 (es) 2021-09-29
AU2013237896B2 (en) 2017-11-02
PL3278811T3 (pl) 2021-08-02
JP7108724B2 (ja) 2022-07-28
CA2869070A1 (en) 2013-10-03
JP2019131582A (ja) 2019-08-08
EP3278811A1 (en) 2018-02-07
MX354598B (es) 2018-03-12
BR112014024308B1 (pt) 2021-11-30
EP2830645B1 (en) 2017-08-30
DK2830645T3 (da) 2017-11-20
HK1249038A1 (en) 2018-10-26
DK3278811T3 (da) 2021-03-01
AU2019202401B2 (en) 2020-10-15
JP2017149746A (ja) 2017-08-31
AU2020260539A1 (en) 2020-11-26
PT2830645T (pt) 2017-11-28
JP2015514096A (ja) 2015-05-18
EP3842059A1 (en) 2021-06-30
MX2014011838A (es) 2015-03-09
HK1206632A1 (en) 2016-01-15
BR112014024308A8 (pt) 2018-01-23
US20160346353A1 (en) 2016-12-01
PL2830645T3 (pl) 2018-01-31
WO2013149163A1 (en) 2013-10-03
EP3278811B1 (en) 2020-12-02
IL288785B2 (en) 2023-03-01
AU2019202401A1 (en) 2019-05-02
BR112014024308A2 (pt) 2017-08-08
EP2830645A1 (en) 2015-02-04
AU2018200592A1 (en) 2018-02-15
IL234882A0 (en) 2014-12-31
US20230117985A1 (en) 2023-04-20
CN104321072A (zh) 2015-01-28
CN106511971A (zh) 2017-03-22
IL273186B (en) 2022-01-01

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