BR112014024308B1 - Uso de neuregulina para tratar lesão de nervo periférico - Google Patents

Uso de neuregulina para tratar lesão de nervo periférico Download PDF

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Publication number
BR112014024308B1
BR112014024308B1 BR112014024308-5A BR112014024308A BR112014024308B1 BR 112014024308 B1 BR112014024308 B1 BR 112014024308B1 BR 112014024308 A BR112014024308 A BR 112014024308A BR 112014024308 B1 BR112014024308 B1 BR 112014024308B1
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BR
Brazil
Prior art keywords
weeks
neuregulin
injury
nerve
ggf2
Prior art date
Application number
BR112014024308-5A
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English (en)
Portuguese (pt)
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BR112014024308A8 (pt
BR112014024308A2 (pt
Inventor
Anthony O. Caggiano
Anthony J. Bella
Anindita Ganguly
Jennifer Iaci
Thomas Parry
Raymond Warrern Colburn
Original Assignee
Acorda Therapeutics, Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Acorda Therapeutics, Inc filed Critical Acorda Therapeutics, Inc
Publication of BR112014024308A2 publication Critical patent/BR112014024308A2/pt
Publication of BR112014024308A8 publication Critical patent/BR112014024308A8/pt
Publication of BR112014024308B1 publication Critical patent/BR112014024308B1/pt

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1883—Neuregulins, e.g.. p185erbB2 ligands, glial growth factor, heregulin, ARIA, neu differentiation factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
BR112014024308-5A 2012-03-30 2013-03-29 Uso de neuregulina para tratar lesão de nervo periférico BR112014024308B1 (pt)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US201261618381P 2012-03-30 2012-03-30
US61/618,381 2012-03-30
US201261674060P 2012-07-20 2012-07-20
US61/674,060 2012-07-20
US201261693589P 2012-08-27 2012-08-27
US201261693585P 2012-08-27 2012-08-27
US61/693,585 2012-08-27
US61/693,589 2012-08-27
US201361785419P 2013-03-14 2013-03-14
US61/785,419 2013-03-14
PCT/US2013/034634 WO2013149163A1 (en) 2012-03-30 2013-03-29 Use of neuregulin to treat peripheral nerve injury

Publications (3)

Publication Number Publication Date
BR112014024308A2 BR112014024308A2 (pt) 2017-08-08
BR112014024308A8 BR112014024308A8 (pt) 2018-01-23
BR112014024308B1 true BR112014024308B1 (pt) 2021-11-30

Family

ID=48128617

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014024308-5A BR112014024308B1 (pt) 2012-03-30 2013-03-29 Uso de neuregulina para tratar lesão de nervo periférico

Country Status (15)

Country Link
US (3) US20150094263A1 (https=)
EP (3) EP3842059A1 (https=)
JP (4) JP6420233B2 (https=)
CN (2) CN104321072A (https=)
AU (4) AU2013237896B2 (https=)
BR (1) BR112014024308B1 (https=)
CA (1) CA2869070A1 (https=)
DK (2) DK3278811T3 (https=)
ES (2) ES2647917T3 (https=)
IL (3) IL288785B2 (https=)
MX (1) MX354598B (https=)
NZ (1) NZ700546A (https=)
PL (2) PL2830645T3 (https=)
PT (2) PT2830645T (https=)
WO (1) WO2013149163A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110166068A1 (en) 2008-07-17 2011-07-07 Acorda Therapeutics, Inc. Therapeutic Dosing of a Neuregulin or a Subsequence Thereof for Treatment or Pro-phylaxis of Heart Failure
NZ625673A (en) 2009-10-14 2015-11-27 Acorda Therapeutics Inc Use of a neuregulin to treat peripheral nerve injury
ITUB20155471A1 (it) * 2015-11-11 2017-05-11 Univ Degli Studi Di Torino Coniugato della neuregulina 1 per il trattamento delle lesioni dei nervi periferici
WO2017096358A1 (en) * 2015-12-04 2017-06-08 University Of Iowa Research Foundation Apparatus, systems and methods for predicting, screening and monitoring of encephalopathy / delirium
US11511136B2 (en) 2017-11-17 2022-11-29 The Research Foundation For The State University Of New York Method for treating damaged peripheral nerves using x-ray microbeam irradiation
CN110946991A (zh) * 2018-09-27 2020-04-03 广州中医药大学(广州中医药研究院) 神经调节蛋白1的应用
WO2021022254A2 (en) * 2019-08-01 2021-02-04 Mark Evans Methods and apparatus for reducing the risk, and identifying the existence, of neurological injury to a human fetus during and before labor
CN116116737B (zh) * 2023-04-14 2023-06-30 新华手术器械有限公司 止血钳毛坯自动上料装置及使用方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7037A (en) 1850-01-22 Grid-ikon slide-valve
US888A (en) 1838-08-20 perkins
US5530109A (en) 1991-04-10 1996-06-25 Ludwig Institute For Cancer Research DNA encoding glial mitogenic factors
US5716930A (en) 1991-04-10 1998-02-10 Ludwig Institute For Cancer Research Glial growth factors
US6087323A (en) * 1992-04-03 2000-07-11 Cambridge Neuroscience, Inc. Use of neuregulins as modulators of cellular communication
US7037888B1 (en) 1992-04-03 2006-05-02 Acorda Therapeutics, Inc. Methods for treating muscle diseases and disorders
AU745324B2 (en) * 1997-10-14 2002-03-21 Cenes Pharmaceuticals, Inc. Therapeutic methods comprising use of a neuregulin
AU2001274947B2 (en) * 2000-05-23 2006-08-17 Acorda Therapeutics, Inc. Nrg-2 nucleic acid molecules, polypeptides, and diagnostic and therapeutic methods
US20100286043A1 (en) * 2007-10-05 2010-11-11 Tufts Medical Center, Inc. Use of neuregulin-1 in reducing brain damage
WO2009108390A2 (en) * 2008-02-29 2009-09-03 Acorda Therapeutics, Inc. Method for achieving desired glial growth factor 2 plasma levels
US20110166068A1 (en) * 2008-07-17 2011-07-07 Acorda Therapeutics, Inc. Therapeutic Dosing of a Neuregulin or a Subsequence Thereof for Treatment or Pro-phylaxis of Heart Failure
KR101237927B1 (ko) * 2009-05-07 2013-03-04 (주)문엔제이 신경손상 및 신경질환 예방 또는 치료용 약학조성물
NZ625673A (en) * 2009-10-14 2015-11-27 Acorda Therapeutics Inc Use of a neuregulin to treat peripheral nerve injury
EP2603221A4 (en) * 2010-08-13 2014-02-26 Univ Georgetown GGF2 AND METHOD FOR ITS APPLICATION

Also Published As

Publication number Publication date
NZ700546A (en) 2017-05-26
IL273186A (en) 2020-04-30
IL234882B (en) 2020-03-31
PT3278811T (pt) 2021-03-03
US20150094263A1 (en) 2015-04-02
IL288785B (en) 2022-11-01
AU2013237896A1 (en) 2014-10-16
ES2647917T3 (es) 2017-12-27
IL288785A (en) 2022-02-01
JP2021059605A (ja) 2021-04-15
ES2857810T3 (es) 2021-09-29
AU2013237896B2 (en) 2017-11-02
PL3278811T3 (pl) 2021-08-02
JP7108724B2 (ja) 2022-07-28
CA2869070A1 (en) 2013-10-03
JP2019131582A (ja) 2019-08-08
JP6420233B2 (ja) 2018-11-07
EP3278811A1 (en) 2018-02-07
MX354598B (es) 2018-03-12
EP2830645B1 (en) 2017-08-30
DK2830645T3 (da) 2017-11-20
HK1249038A1 (en) 2018-10-26
DK3278811T3 (da) 2021-03-01
AU2019202401B2 (en) 2020-10-15
JP2017149746A (ja) 2017-08-31
AU2020260539A1 (en) 2020-11-26
PT2830645T (pt) 2017-11-28
JP2015514096A (ja) 2015-05-18
EP3842059A1 (en) 2021-06-30
MX2014011838A (es) 2015-03-09
HK1206632A1 (en) 2016-01-15
BR112014024308A8 (pt) 2018-01-23
US20160346353A1 (en) 2016-12-01
PL2830645T3 (pl) 2018-01-31
WO2013149163A1 (en) 2013-10-03
EP3278811B1 (en) 2020-12-02
IL288785B2 (en) 2023-03-01
AU2019202401A1 (en) 2019-05-02
BR112014024308A2 (pt) 2017-08-08
EP2830645A1 (en) 2015-02-04
AU2018200592A1 (en) 2018-02-15
IL234882A0 (en) 2014-12-31
US20230117985A1 (en) 2023-04-20
CN104321072A (zh) 2015-01-28
CN106511971A (zh) 2017-03-22
IL273186B (en) 2022-01-01

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Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 29/03/2013, OBSERVADAS AS CONDICOES LEGAIS.

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 11A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2768 DE 23-01-2024 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.