JP6401172B2 - 貧血の治療方法 - Google Patents

貧血の治療方法 Download PDF

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Publication number
JP6401172B2
JP6401172B2 JP2015539751A JP2015539751A JP6401172B2 JP 6401172 B2 JP6401172 B2 JP 6401172B2 JP 2015539751 A JP2015539751 A JP 2015539751A JP 2015539751 A JP2015539751 A JP 2015539751A JP 6401172 B2 JP6401172 B2 JP 6401172B2
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gdf11
seq
actriia
polypeptide
actriib
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Japanese (ja)
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JP2016503398A5 (https=
JP2016503398A (ja
Inventor
スング ビクトリア
スング ビクトリア
チョプラ ラジェシュ
チョプラ ラジェシュ
ヘルミネ オリビエル
ヘルミネ オリビエル
クルズモウラ イバン
クルズモウラ イバン
ドウシオト ミチャエル
ドウシオト ミチャエル
トロバトイマシエル トヒアゴ
トロバトイマシエル トヒアゴ
フリコト アウレリエ
フリコト アウレリエ
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Celgene Corp
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Celgene Corp
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/6425—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a receptor, e.g. CD4, a cell surface antigen, i.e. not a peptide ligand targeting the antigen, or a cell surface determinant, i.e. a part of the surface of a cell
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2015539751A 2012-10-24 2013-10-23 貧血の治療方法 Active JP6401172B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261718128P 2012-10-24 2012-10-24
US61/718,128 2012-10-24
PCT/US2013/066353 WO2014066487A2 (en) 2012-10-24 2013-10-23 Methods for treating anemia

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2018131952A Division JP2018184430A (ja) 2012-10-24 2018-07-12 貧血の治療方法

Publications (3)

Publication Number Publication Date
JP2016503398A JP2016503398A (ja) 2016-02-04
JP2016503398A5 JP2016503398A5 (https=) 2016-12-08
JP6401172B2 true JP6401172B2 (ja) 2018-10-10

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JP2015539751A Active JP6401172B2 (ja) 2012-10-24 2013-10-23 貧血の治療方法
JP2018131952A Pending JP2018184430A (ja) 2012-10-24 2018-07-12 貧血の治療方法
JP2020108654A Withdrawn JP2020183390A (ja) 2012-10-24 2020-06-24 貧血の治療方法

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JP2018131952A Pending JP2018184430A (ja) 2012-10-24 2018-07-12 貧血の治療方法
JP2020108654A Withdrawn JP2020183390A (ja) 2012-10-24 2020-06-24 貧血の治療方法

Country Status (9)

Country Link
US (1) US20150266950A1 (https=)
EP (2) EP2911682A4 (https=)
JP (3) JP6401172B2 (https=)
CN (3) CN112933223A (https=)
AU (4) AU2013334660B2 (https=)
CA (1) CA2889286A1 (https=)
HK (1) HK1214504A1 (https=)
NZ (1) NZ747350A (https=)
WO (1) WO2014066487A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020183390A (ja) * 2012-10-24 2020-11-12 セルジーン コーポレイション 貧血の治療方法

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Publication number Publication date
EP2911682A2 (en) 2015-09-02
JP2018184430A (ja) 2018-11-22
CN112957462A (zh) 2021-06-15
AU2018256635A1 (en) 2018-11-22
US20150266950A1 (en) 2015-09-24
AU2022201923A1 (en) 2022-04-14
CN104981250A (zh) 2015-10-14
EP3527219A1 (en) 2019-08-21
EP2911682A4 (en) 2016-03-23
WO2014066487A3 (en) 2014-06-19
NZ747350A (en) 2020-07-31
JP2020183390A (ja) 2020-11-12
AU2020203198A1 (en) 2020-06-11
AU2013334660B2 (en) 2018-08-09
WO2014066487A2 (en) 2014-05-01
CN112933223A (zh) 2021-06-11
AU2020203198B2 (en) 2021-12-23
CA2889286A1 (en) 2014-05-01
AU2013334660A1 (en) 2015-05-14
HK1214504A1 (zh) 2016-07-29
JP2016503398A (ja) 2016-02-04

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