JP6386448B2 - ブタインターフェロンアルファ及びブタインターフェロンガンマを同時に発現する組換えアデノウィルス - Google Patents

ブタインターフェロンアルファ及びブタインターフェロンガンマを同時に発現する組換えアデノウィルス Download PDF

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JP6386448B2
JP6386448B2 JP2015514906A JP2015514906A JP6386448B2 JP 6386448 B2 JP6386448 B2 JP 6386448B2 JP 2015514906 A JP2015514906 A JP 2015514906A JP 2015514906 A JP2015514906 A JP 2015514906A JP 6386448 B2 JP6386448 B2 JP 6386448B2
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porcine
foot
porcine interferon
recombinant adenovirus
mouth disease
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JP2015523858A (ja
JP2015523858A5 (https=
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ス ミ キム
ス ミ キム
ジョン ヒョン パク
ジョン ヒョン パク
クァン ニョン リー
クァン ニョン リー
ヨウン ジョン コー
ヨウン ジョン コー
ヒャン シム リー
ヒャン シム リー
ユン キュン シン
ユン キュン シン
ビョウン ハン キム
ビョウン ハン キム
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Republic Of Korea Management Ministry Of Agriculture Food And Rural Affairs Animal And Plant Quarantine Agency
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Republic Of Korea Management Ministry Of Agriculture Food And Rural Affairs Animal And Plant Quarantine Agency
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    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C12N15/861—Adenoviral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/57—IFN-gamma
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32111—Aphthovirus, e.g. footandmouth disease virus
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    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron

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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
JP2015514906A 2012-05-31 2013-05-31 ブタインターフェロンアルファ及びブタインターフェロンガンマを同時に発現する組換えアデノウィルス Active JP6386448B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR20120058410A KR101329348B1 (ko) 2012-05-31 2012-05-31 돼지 인터페론 알파-돼지 인터페론 감마를 동시 발현하는 재조합 아데노바이러스
KR10-2012-0058410 2012-05-31
PCT/KR2013/004784 WO2013180501A1 (ko) 2012-05-31 2013-05-31 돼지 인터페론 알파-돼지 인터페론 감마를 동시 발현하는 재조합 아데노바이러스

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JP2015523858A JP2015523858A (ja) 2015-08-20
JP2015523858A5 JP2015523858A5 (https=) 2016-07-21
JP6386448B2 true JP6386448B2 (ja) 2018-09-05

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JP2015514906A Active JP6386448B2 (ja) 2012-05-31 2013-05-31 ブタインターフェロンアルファ及びブタインターフェロンガンマを同時に発現する組換えアデノウィルス

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EP (1) EP2871240B1 (https=)
JP (1) JP6386448B2 (https=)
KR (1) KR101329348B1 (https=)
CN (1) CN104583410B (https=)
ES (1) ES2662948T3 (https=)
WO (1) WO2013180501A1 (https=)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107286257A (zh) * 2017-08-09 2017-10-24 芜湖英特菲尔生物制品产业研究院有限公司 一种重组猪长效干扰素α及制备此长效干扰素的融合蛋白及其制备方法
KR102384683B1 (ko) * 2020-05-07 2022-04-11 대한민국 구제역 바이러스 억제 활성을 갖는 신규한 돼지 인터페론-알파 융합 단백질 및 이의 용도
CN115595312A (zh) * 2021-06-28 2023-01-13 中国农业大学（Cn） 一种重组腺病毒及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8058248B2 (en) * 2001-04-26 2011-11-15 The United States Of America As Represented By The Secretary Of Agriculture Foot and mouth disease virus vaccine comprising interferons
US7485291B2 (en) 2003-06-03 2009-02-03 Cell Genesys, Inc. Compositions and methods for generating multiple polypeptides from a single vector using a virus derived peptide cleavage site, and uses thereof
US7632509B2 (en) 2005-07-19 2009-12-15 Biosante Pharmaceuticals, Inc. Methods to express recombinant proteins from lentiviral vectors
BRPI0618441B8 (pt) * 2005-11-10 2021-07-27 Genvec Inc vetor adenoviral
US7833533B2 (en) * 2008-04-24 2010-11-16 The United States Of America As Represented By The Secretary Of Agriculture Enhanced antiviral activity against foot and mouth disease

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Publication number Publication date
WO2013180501A1 (ko) 2013-12-05
EP2871240B1 (en) 2017-12-20
JP2015523858A (ja) 2015-08-20
CN104583410B (zh) 2017-09-22
KR101329348B1 (ko) 2013-11-15
ES2662948T3 (es) 2018-04-10
CN104583410A (zh) 2015-04-29
EP2871240A4 (en) 2016-01-27
EP2871240A1 (en) 2015-05-13

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