JP6292647B1 - Detection tool, method for manufacturing the same, and method for evaluating a test substance - Google Patents

Abstract

[PROBLEMS] To eliminate the presence of contaminants in a suspension such as muddy water and the concentration thereof by using a detection material or the like in which a coloring reagent is supported on a substrate, and the like. And a detection tool suitable for simple measurement. A detection tool 10 having a packaging structure in which a detection material 1 is encapsulated, wherein a first surface of the packaging structure has a layer of a porous material (nonwoven fabric 31), and a second of the packaging structure. A detection tool 10 having a packaging structure in which a surface has a transparent layer (transparent film 21) and an adhesive portion 4 is provided around a first surface and a second surface. [Selection] Figure 1

Description

  The present invention relates to a detection tool and a method for manufacturing the detection tool. The present invention also relates to a method for evaluating a substance to be inspected using the detection tool. This detection tool can be used for environmental analysis of soil, water quality, industrial waste, and as a physics and chemistry teaching material for schools.

  Conventionally, analysis tools for analyzing water quality, gas, and the like by a simple method have been proposed. For example, Patent Document 1 discloses an invention relating to a simple analysis tool. This Patent Document 1 relates to an instrument that easily measures an aqueous solution, and includes a plug member that encloses a color reaction reagent in a transparent container that can be seen through and can be pulled out so as to penetrate inside and outside of the sealed container. A simple analyzer characterized by the above is disclosed. By pulling out the plug member, this simple analyzer can easily obtain a through hole for discharging the air in the sealed container and sucking in the liquid to be inspected.

  Patent Document 2 relates to a gas measuring instrument using a material in which a coloring reagent is supported on a solid, and has a detection agent composed of a reagent that changes color in response to a specific gas. A detection member is disclosed that detects the concentration of the specific gas contained in the air in contact with the surrounding air.

  Patent Documents 3 and 4 disclose detection materials for detecting metal ions and environmental pollutants. The detection materials disclosed in these documents are those in which a color former or the like is supported on a base material, and by using these, the presence or absence of metal ions and environmental pollutants can be evaluated quickly by a simple method. .

Japanese Patent No. 4125603 JP 2003-270236 A Japanese Patent Laying-Open No. 2015-083971 Japanese Patent Laying-Open No. 2015-152514

  Many detection materials and the like disclosed in Patent Documents 1 to 4 evaluate the presence or absence of coloration when reacted with a specific substance as an evaluation method. When this evaluation is performed, if the substance to be evaluated is a suspension such as muddy water, it may be difficult to determine the presence or absence of coloration due to the color or turbidity of the suspension. In order to eliminate the influence of such a suspension, it is conceivable to filter the suspension in advance, but it may be necessary to prepare an instrument for filtration. Sometimes it was required.

  Under such circumstances, the present invention is suitable for simple measurement of the presence / absence and concentration of contaminants in suspended substances (such as muddy water) using the detection materials disclosed in Patent Document 3 and Patent Document 4. A detection tool is provided.

  As a result of intensive studies to solve the above problems, the present inventor has found that the following inventions meet the above object, and have reached the present invention.

That is, the present invention relates to the following inventions.
<1> A detection tool having a packaging structure containing a detection material,
Having a layer of porous material as the first surface of the packaging structure;
As a second surface of the packaging structure has a transparent layer made of transparent resin,
The detection tool which is a packaging structure which has an adhesion part around the 1st surface and the 2nd surface.
<2> The detection tool according to <1>, wherein the detection material is a detection material having at least one shape selected from the group consisting of powder, granule, granule, gel, and sheet.
<3> The detection tool according to <1> or <2>, including a color sample portion of the detection material.
<4> The detection tool according to any one of <1> to <3>, wherein the adhesive portion is a welded portion.
<5> a step of disposing a detection material between a base material having a porous material layer as a first surface and a base material having a transparent layer as a second surface;
The base material having a porous material layer as the first surface of the packaging structure and the base material having a transparent resin-made transparent layer as the second surface of the packaging structure are welded by heat welding. The manufacturing method of the detection tool which has the process of setting it as a packaging structure by providing a part.
<6> A method for evaluating a test substance using the detection tool according to any one of <1> to <4>,
Bringing the first surface of the detection tool into contact with the test substance in a wet state;
By contacting the detection material in the detection tool with the component of the test substance that has permeated through the first surface, and observing the presence or absence of reaction of the detection material from the second surface,
An evaluation method for evaluating the presence or absence of a measurement target of a detection material in a test substance

  If the detection tool of this invention is used, the filtration process at the time of measurement of a suspension can be skipped, shortening of analytical work time and reduction of the instrument used can be expected, and evaluation can be performed by a simple method.

It is a figure which shows the general | schematic cross section of the detection tool which concerns on 1st embodiment of this invention. It is a top view of the detection tool which concerns on 1st embodiment of this invention. It is a figure for demonstrating the manufacturing method of the detection tool which concerns on 2nd embodiment of this invention. It is a figure which shows the schematic sectional drawing of the detection tool which concerns on 3rd embodiment of this invention. It is a figure which shows the detection tool which concerns on the Example of this invention. It is a figure which shows the detection tool which concerns on the Example of this invention. It is a figure which shows the detection tool which concerns on the Example of this invention.

  DESCRIPTION OF EMBODIMENTS Embodiments of the present invention will be described in detail below. However, the description of constituent elements described below is an example (representative example) of an embodiment of the present invention, and the present invention will be described below unless the gist thereof is changed. It is not limited to the contents.

[First embodiment]
1 and 2 are schematic views showing a detection tool according to an embodiment of the present invention. FIG. 1 shows an outline when observed from a cross-section of the detection tool 10. FIG. 2 shows an outline when the detection tool 10 is viewed in plan.

  The detection tool 10 has a packaging structure in which a transparent film 21 and a non-woven fabric 31 are overlapped, and adhesive portions 4 in which end portions thereof are heat-welded are provided on the four surrounding sides. The detection material 1 is included in the package structure of the detection tool 10. Moreover, in this packaging structure of the detection tool 10, the transparent film 21 becomes the second surface of the transparent layer, and the nonwoven fabric 31 becomes the first surface. That is, it is a detection tool 10 having a packaging structure in which the detection material 1 is encapsulated, the first surface of the packaging structure has a layer of a nonwoven fabric 31, and the second surface of the packaging structure is a transparent layer. The detection tool 10 is a packaging structure having a film 21 and having an adhesive portion 4 around a first surface and a second surface. Moreover, the detection tool 10 also has the color sample part 5 as shown in FIG.

[Detection material]
The detection tool 1 contains the detection material 1. As the detection material, a detection material that is colored by reacting with a predetermined component contained in a substance to be inspected such as suspension water to be inspected is used. As the detection material 1, a material that can be included in the packaging structure of the detection tool 10 can be appropriately used. Specifically, those having at least one shape selected from the group consisting of powder, granule, granule, gel, and sheet are preferably used. That is, the detection material 1 may be used in combination of a plurality of shapes.

  A typical example of the detection material 1 is one in which a color former is supported on a base material. As such a substrate, at least one substrate selected from the group consisting of a water-absorbing polymer, white carbon, silica particles, porous glass particles, and high silica zeolite is preferably used. When such a base material is used, the detection material is less likely to leak into the packaging structure of the detection tool 10 before and after the inspection, and it is easy to check the presence or absence of coloration.

  Further, as the color former carried on the detection material 1, a suitable color former is selected in consideration of the component to be inspected and suitability with the substrate. As such a detection material 1, for example, a detection material disclosed in Patent Documents 3 and 4 is preferably used.

[Transparent layer]
As the second surface of the packaging structure of the detection tool 10, the detection tool 10 has a transparent film 21. This transparent film functions as a transparent layer, and the detection material 1 contained in the detection tool 10 can be visually recognized through this transparent film.

  The transparent film 21 is a transparent layer of the detection tool according to the present invention. In the present invention, the transparent layer is a shape of a surface that occupies a part of various packaging structures such as a film, a sheet, a plate, a box, and a hemisphere. It is arranged with. The second surface may be a shape such as a curved surface as well as a flat surface.

  This transparent layer is made of a transparent resin. Specific transparent resins include polyolefin (polyethylene, polypropylene, polybutylene), polyester, polyethylene terephthalate, acrylic, polycarbonate, polyacrylonitrile, polyvinyl chloride, polystyrene, ethylene vinyl alcohol. And those using at least one resin selected from the group consisting of polyvinyl alcohol, nylon, barrier nylon, cellulose, and fluorocarbon resin. Further, the resin described above may be a resin copolymer as described above, or a composite molded by coextrusion molding of a plurality of resins when forming for a transparent layer. Moreover, you may use it, performing transparent vapor deposition processing, such as a silica vapor deposition, suitably. If it is made of a transparent resin, it is easy to perform molding with excellent adhesion to the porous material.

  For example, the transparent film 21 may be a film formed mainly of a polyethylene film or a polyolefin-based thermoplastic resin such as a polypropylene film. The resin forming this film can be selected according to the use environment of the detection tool 10 and the component to be detected. In particular, the above-described polyethylene film and polypropylene film are preferably used because they have water resistance and resistance to many substances, and stabilize the form of the detection tool 10 before and after detection.

  The transparent layer may be a non-colored material as long as the detection material 1 can be visually confirmed and the presence or absence of the coloration can be sufficiently confirmed, and the color that is easy to confirm the coloration in relation to the coloration. It is good also as a layer of.

[color sample]
Furthermore, as shown in FIG. 2, the detection tool 10 has a color sample portion 5. The color sample portion 5 can be set to the same color as the color sample when the detection material 1 reacts and colors when it comes into contact with the test target substance. In order to provide the color sample portion 5, for example, a printable material can be used as the transparent layer. Using such printable materials, the color that will be the color sample when the detection material is colored is printed on the surface of the transparent layer film or container, as in the pack test of conventional products. There is no need to carry a separate color sample, and the test result can be confirmed by comparing the color printed on the transparent layer with the color of the detection material in the detection tool. Thereby, the trouble of taking out the detection tool from the suspension and comparing it with another color sample can be saved.

[Layer of porous material]
As a first surface of the packaging structure of the detection tool 10, the detection tool 10 has a nonwoven fabric 31 that is a layer of a porous material. The nonwoven fabric 31 is infiltrated with a liquid such as a suspension to be inspected. Furthermore, the nonwoven fabric 31 suppresses the passage of the suspended substance in the suspension so that only the suspension liquid penetrates into the packaging structure of the detection tool 10. As a result, the liquid that has permeated into the packaging structure is in contact with the detection material 1 contained therein, and can be prevented from being colored by a suspended substance that can be included in the substance to be inspected.

  The nonwoven fabric 31 is the first aspect of the present invention, and a porous material can be used for this portion. The porous material that can be used here is a material such as a film or sheet having a substantially porous structure that suppresses the passage of suspended substances in the suspension and allows the liquid to permeate. Or a woven fabric, a porous membrane, etc. can be used.

  Porous materials include polyolefin (polyethylene, polypropylene, polybutylene), polyester, polyamide, nylon, polyethylene terephthalate, cellulose, cellulose mixed ester, cellulose acetate, fluorocarbon resin A material using at least one material selected from the group consisting of a system, a polyether sulfone system, and a rayon system is preferably used. These materials may be appropriately subjected to a hydrophilic treatment coating treatment. If such a material is used, it is easy to perform molding with excellent adhesiveness by using the above-described transparent resin for the transparent layer.

  In addition, since the liquid permeability affects separation of suspended substances and the contact speed between the liquid and the detection material 10 contained therein, the porous material is appropriately selected according to the use environment of the detection tool 10 and the like. It can be set as the structure which selected the hole diameter of a (nonwoven fabric etc.), a supplementary particle diameter, a fabric weight, thickness, and a raw material.

  For example, as this nonwoven fabric 31, it is preferable to use the nonwoven fabric which used fibers, such as thermoplastic resins, such as polyethylene and a polypropylene, as the raw material.

  The specific pore state of this porous material is appropriately selected depending on the use of the detection material contained in the porous material and the entire detection tool. As an index of the state of the pores, a reserved particle diameter, a pore diameter, or the like is used as an index depending on a more specific type of porous material. The retained particle diameter of the porous material is preferably 10 μm or less, more preferably 5 μm or less, and particularly preferably 3 μm or less. For example, a nonwoven fabric is often judged to be applied to the detection tool of the present invention based on the retained particle diameter. The average pore diameter of the porous material is preferably 10 μm or less, more preferably 6 μm or less, and particularly preferably 4 μm or less. Using such a porous material, it is possible to achieve a flow rate suitable for detection of many suspensions and to prevent the suspension from entering the packaging structure, and to check the color of the detection material properly. Can be done.

[Adhesive part (welded part)]
The detection tool 10 is square when viewed in plan, and the periphery of the four sides is heat-sealed (heat-sealed) around the non-woven fabric 31 that is the first surface and the second surface 2, It has the adhesion part 4 of the state welded. The configuration in which the adhesive portion of the packaging structure of the detection material 10 is provided by the adhesive portion 4 is excellent in terms of the formability of the detection material 10 as a whole and the leakage of the detection material 1 contained before and after use. . Therefore, the nonwoven fabric 31 used as the first surface and the transparent film 21 of the transparent layer used as the second surface so that the bonded portion can be a welded portion by heat sealing are made of a thermoplastic resin having a high affinity ( For example, it is preferable to use a both-polyolefin resin.

  Depending on the application of the detection tool 10, the adhesive portion 4 may be provided with a seal with glue or an adhesive, or a stitched adhesive portion. However, when glue or adhesive is used, it may affect the chemical reaction of the detection material. On the other hand, if it is a welding part in a heat seal, it is excellent in the point that it is hard to produce the influence of the chemical reaction by such another component.

[Detection tool]
The detection tool 10 can be brought into contact with a test object such as soil or liquid to detect the presence or the concentration of the target substance to which the detection material 1 contained in the detection tool 10 reacts. At this time, the inside of the detection tool 10 penetrates mainly through the layer of the non-woven fabric 31 as described above. When the detection material 1 comes into contact with the passed liquid and the coloring reagent carried on the detection material reacts with the absorbed solution, coloration occurs. The presence or absence of a detection target substance such as a contaminant can be determined from the color to be colored, and may differ depending on the combination of the color former and the detection target substance. The color of the detection material can be visually confirmed from the surface of the transparent film 21. In the first embodiment, the detection material 1 is included in one space. However, the detection tool of the present invention includes a plurality of packaging structures that include different detection materials. Alternatively, a plurality of types of detection materials may be included in the same packaging structure.

  Here, the evaluation method using the detection tool of the present invention will be described more specifically. For example, when evaluating a substance to be inspected using the detection tool 10, the nonwoven fabric 31 that is the first surface of the detection tool 10 is brought into contact with the test object in a wet state. When the soil or the like to be inspected is dry, it is preferable to make it wet by spraying water as appropriate. Then, the component to be inspected that has permeated through the surface of the nonwoven fabric 31 is brought into contact with the detection material 1 in the detection tool 10, and the presence or absence of a reaction with the detection material 10 is observed from the transparent film 21 side that is the second surface. By doing, the presence or absence of the measuring object of the detection material 10 in a test object can be evaluated.

  Since the detection tool of the present invention is simple to use, it can be used without specialized knowledge. As a specific method, the detection tool 10 is allowed to stand for a predetermined time in a place where water is added to and mixed with the soil sampled from the measurement point surface layer or underground part of the soil to be polluted. The presence or absence of heavy metals is determined visually by the change in the color of the detection material filled in.

  In order to measure a suspension such as muddy water, a process of filtering suspended substances is required, but by using the detection tool 10 having a packaging structure as in the present invention, the filtration process is omitted unlike the prior art. Surveys can be conducted. For this reason, a complicated operation is not required in the measurement. Furthermore, since the packaging structure of the detection tool 10 can be recovered after the detection is completed, the recovery can be easily performed.

[Second Embodiment: Manufacturing Method of Detection Tool 10]
A method for manufacturing a detection tool according to the present invention will be described with reference to FIGS. The detection tool 10 can also be manufactured by this detection tool manufacturing method.
First, the transparent film 21 cut into a substantially rectangular shape of the same size and the nonwoven fabric 31 are overlapped, as shown in FIG. 3A, except for the opening for enclosing the detection material, The other three sides are heat-sealed to form the welded portion 41. The detection material 1 is placed inside a bag-shaped packaging structure obtained by providing the welded portion 41.
After the detection material 1 is put in, the remaining side where the transparent film 21 and the nonwoven fabric 31 are not welded is welded by a heating device 6 for heat sealing as shown in FIG. 3B. A portion 42 is provided. Accordingly, the welded portion 41 and the welded portion 42 are hermetically sealed and sealed, and a welded portion (adhesive portion) that does not leak out the detection material contained in the packaging structure.

[Third embodiment]
FIG. 4 is a schematic view showing another detection tool according to the embodiment of the present invention. FIG. 4 shows an outline when observed from the cross section of the detection tool 11.

  The detection tool 11 has a packaging structure in which the transparent container 22 and the porous film 32 are overlapped, and the adhesive portions 4 whose ends are heat-welded are provided on the four surrounding sides. The detection material 1 is encapsulated inside the packaging structure of the detection tool 11. Moreover, in this packaging structure of the detection tool 11, the transparent container 22 becomes the second surface of the transparent layer, and the porous membrane 32 becomes the first surface. That is, the detection tool 11 has a packaging structure in which the detection material 1 is included, the first surface of the packaging structure has a layer of the porous film 32, and the second surface of the packaging structure is a transparent layer. It is the detection tool 11 which is the packaging structure which has the transparent container 22 which becomes and has the adhesion part 4 around the 1st surface and the 2nd surface. As the transparent container and the porous film used for the detection tool 11, those described in the first embodiment and the second embodiment can be appropriately used.

  EXAMPLES Hereinafter, although an Example demonstrates this invention further in detail, this invention is not limited to a following example, unless the summary is changed.

[Layer of porous material]
[Nonwoven fabric]
・ Nonwoven fabric (1) “Precise AS066” (Aperture diameter 3.9 μm, thickness 66 μm) manufactured by Asahi Kasei Fibers Co., Ltd.
[Membrane filter]
・ Membrane filter (1) Advantech Toyo Co., Ltd. “A045A090C” cellulose mixed ester type, pore size 0.45 μm

[Transparent layer]
[Transparent film]
・ Polypropylene film (laminated film of biaxially stretched polypropylene film and unstretched polypropylene film, thickness of about 60 μm)
[Transparent container]
-A container having a hemispherical convex portion made of polypropylene (square size 20 mm × 20 mm when viewed in plan, φ10 mm of convex portion near the center, depth 5 mm)

[Detection material]
・ Detection material for fluorine (1)
Alfusson (manufactured by Dojin Chemical) is dissolved in pure water to prepare a 0.11 g / 10 mL solution. This total amount was absorbed by 2 g of Aqua Coke (manufactured by Sumitomo Seika Co., Ltd.) to obtain a gel-like “detection material for fluorine (1)”.
・ Detection material for boron (1)
“Azomethine H (8-hydroxy-1- (salicylideneamino) -3,6-naphthalenedisulfonic acid, disodium salt)” (manufactured by Wako Pure Chemical Industries) 1 g, L-ascorbic acid (manufactured by Showa Pharmaceutical Co., Ltd.) 3 g Water-absorbing polymer (Aquakeep (Sumitomo Seika Chemicals) 20g, Sodium dihydrogen phosphate dihydrate 0.4g (Wako Pure Chemical Industries) and Disodium hydrogen phosphate 12 hydrate (Wako Pure Chemical Industries) 0.9 g was mixed to obtain “boron detection material (1)”.

[Detection tool manufacturing process]
-Bag-like detection tool: Cut each non-woven fabric and transparent film into a 30 mm x 40 mm square, and paste them together by heat sealing to form a welded part. The remaining one side was welded to produce a detection tool.
-Hemispherical detection tool (1): Using a membrane filter cut into a 20 mm x 20 mm square according to the size of the transparent container, put the detection material on the convex part of the transparent container, and then use the membrane filter described above. According to the flat part of a transparent container, the circumference | surroundings were heat-welded and the detection tool was manufactured.
-Hemispherical detection tool (2): In accordance with the production of the hemispherical detection tool (1), instead of the surrounding heat welding, it was adhered by “Cemedine Super X” (Cemedine Co., Ltd.).

  Detection tools (A) to (C) were prepared by combining the manufacturing steps of the detection material, the porous material, the transparent layer, and the detection device as shown in Table 1. The detection tool (C) was prepared as a detection tool having a configuration in which different detection materials were enclosed in the left part and the right part.

[test]
・ Test with boron-containing soil 10 g of boron-containing (boron content: 8000 mg / kg) soil and 10 g of distilled water were placed in a 50 mL plastic container, and the container was covered and shaken by hand for 30 seconds. A soil suspension is used. On the other hand, as a control test, a soil suspension was also prepared by replacing the soil with no boron. A detection tool is placed on these soil suspensions. At this time, the aqueous solution from which the soil particles have been separated from the surface of the porous material (nonwoven fabric, etc.) penetrates into the inside of the packaging tool and reacts with the detection material in the packaging device, thereby confirming the presence or absence of coloration due to the presence or absence of the reaction target substance. it can.
・ Test with fluorine-containing soil The above-described test with the boron-containing soil, except that the soil containing fluorine (fluorine content: 8000 mg / kg) was used instead of the boron-containing soil. Then, a test using fluorine-containing soil was conducted.

[Test Example 1] [Test with fluorine-containing soil]
The result of Test Example 1 using fluorine-containing soil is shown in FIG. FIG. 5A shows a state in which two detection tools (A) before the test are arranged. FIG.5 (b) is a figure which shows the state which mounted the detection tool in the suspension liquid which added water to soil. The left container is fluorine-containing soil, and the right container is fluorine-free soil. FIG. 5C shows a state in which only the detection tool (A) is taken out after FIG. 5B. In Test Example 1 shown in FIG. 5, the detection material in the detection tool (A) brought into contact with fluorine-containing soil was colored from purple to blue (left side). On the other hand, in the soil suspension containing no fluorine, the detection material remained reddish purple and there was no coloration (right side).

[Test Example 2] [Test with soil containing boron]
The results of Test Example 2 using boron-containing soil are shown in FIG. FIG. 6A shows a detection tool (B) before the test. FIG.6 (b) is a figure which shows the state which mounted the detection tool in the suspension liquid which added water to soil. The test results with only boron-containing soil are shown. In Test Example 2 shown in FIG. 6, the detection material in the detection tool (B) brought into contact with the soil containing boron was not colored and remained reddish purple because the soil did not contain fluorine. .

[Test Example 3] [Testing with boron-containing soil]
The result of Test Example 3 using boron-containing soil is shown in FIG. FIG. 7A shows a detection tool (C) before the test. FIG.7 (b) is a figure which shows the state which mounted the detection tool in the suspension liquid which added water to soil. In Test Example 3 shown in FIG. 7, the detection tool (C) contains a fluorine detection material in the left portion and a boron detection material in the right portion. Since this was tested by contacting with boron-containing soil, the left fluorine detection material was not colored because the soil did not contain fluorine, but the right boron detection material was not applied to the soil. Since boron was contained, the color changed from orange to yellow. In addition, since the detection material in the right part of this detection material (C) is powdery, the visual recognition becomes more difficult if it is brought into direct contact with the soil suspension. Thus, the detection materials according to the present invention may be arranged in a plurality of arrangements, whereby a plurality of components can be detected simultaneously.

  Each detection tool tested with boron-containing soil and fluorine-containing soil can also easily check the test results without using other special substrates, etc., and the visibility of the test results Was also excellent. Moreover, it was easy to collect the detection tool after the test.

  According to the detection tool of the present invention, suspended water such as muddy water is industrially useful because it can quickly measure the presence or absence of environmental pollutants contained in the suspended water by a simple method.

DESCRIPTION OF SYMBOLS 1 Detection material 10 Detection tool 21 Transparent film 22 Transparent container 31 Nonwoven fabric 32 Porous membrane 4 Adhesion part 41,42 Welding part 5 Color sample part 6 Heating device

Claims (6)

It is a detection tool having a packaging structure containing a detection material,
As a first surface of the packaging structure, it has a porous material layer that inhibits passage of suspended substances and has liquid permeability ,
As a second surface of the packaging structure has a transparent layer made of transparent resin,
The detection tool which is a packaging structure which has an adhesion part around the 1st surface and the 2nd surface.   The detection tool according to claim 1, wherein the detection material is a detection material having at least one shape selected from the group consisting of powder, granule, granule, gel, and sheet.   The detection tool according to claim 1, further comprising a color sample portion of the detection material.   The detection tool according to claim 1, wherein the adhesive portion is a welded portion. Between the base material which has the layer of the porous material which suppresses passage of the suspended matter which makes the 1st surface, and has liquid permeability, and the base material which has the transparent layer made of transparent resin made the 2nd surface Arranging the detection material;
Providing a welded portion by thermally welding a base material having a porous material layer as a first surface of the packaging structure and a base material having a transparent layer as a second surface of the packaging structure; The manufacturing method of the detection tool which has a process made into a packaging structure. A method for evaluating a test substance using the detection tool according to claim 1,
Bringing the first surface of the detection tool into contact with the test substance in a wet state;
By contacting the detection material in the detection tool with the component of the test substance that has permeated through the first surface, and observing the presence or absence of reaction of the detection material from the second surface,
An evaluation method for evaluating the presence or absence of a measurement target of a detection material in a test substance