CN109444122A - A kind of Test paper - Google Patents
A kind of Test paper Download PDFInfo
- Publication number
- CN109444122A CN109444122A CN201811261612.0A CN201811261612A CN109444122A CN 109444122 A CN109444122 A CN 109444122A CN 201811261612 A CN201811261612 A CN 201811261612A CN 109444122 A CN109444122 A CN 109444122A
- Authority
- CN
- China
- Prior art keywords
- colour developing
- sealer
- test paper
- agent
- developing block
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 238000012360 testing method Methods 0.000 title claims abstract description 49
- 208000032843 Hemorrhage Diseases 0.000 claims abstract description 34
- 208000014617 hemorrhoid Diseases 0.000 claims abstract description 22
- 239000003795 chemical substances by application Substances 0.000 claims description 58
- 230000003213 activating effect Effects 0.000 claims description 25
- 238000001514 detection method Methods 0.000 claims description 21
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 17
- 102000001554 Hemoglobins Human genes 0.000 claims description 15
- 108010054147 Hemoglobins Proteins 0.000 claims description 15
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 5
- 239000001301 oxygen Substances 0.000 claims description 5
- 229910052760 oxygen Inorganic materials 0.000 claims description 5
- KFSLWBXXFJQRDL-UHFFFAOYSA-N Peracetic acid Chemical compound CC(=O)OO KFSLWBXXFJQRDL-UHFFFAOYSA-N 0.000 claims description 4
- VZQOBPXGQJXYGY-UHFFFAOYSA-N 2-hydroperoxyethylbenzene Chemical compound OOCCC1=CC=CC=C1 VZQOBPXGQJXYGY-UHFFFAOYSA-N 0.000 claims description 2
- UAIUNKRWKOVEES-UHFFFAOYSA-N 3,3',5,5'-tetramethylbenzidine Chemical group CC1=C(N)C(C)=CC(C=2C=C(C)C(N)=C(C)C=2)=C1 UAIUNKRWKOVEES-UHFFFAOYSA-N 0.000 claims description 2
- RMMXTBMQSGEXHJ-UHFFFAOYSA-N Aminophenazone Chemical compound O=C1C(N(C)C)=C(C)N(C)N1C1=CC=CC=C1 RMMXTBMQSGEXHJ-UHFFFAOYSA-N 0.000 claims description 2
- RCEAADKTGXTDOA-UHFFFAOYSA-N OS(O)(=O)=O.CCCCCCCCCCCC[Na] Chemical group OS(O)(=O)=O.CCCCCCCCCCCC[Na] RCEAADKTGXTDOA-UHFFFAOYSA-N 0.000 claims description 2
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 claims description 2
- 229960000212 aminophenazone Drugs 0.000 claims description 2
- JBIROUFYLSSYDX-UHFFFAOYSA-M benzododecinium chloride Chemical compound [Cl-].CCCCCCCCCCCC[N+](C)(C)CC1=CC=CC=C1 JBIROUFYLSSYDX-UHFFFAOYSA-M 0.000 claims description 2
- ADKBGLXGTKOWIU-UHFFFAOYSA-N butanediperoxoic acid Chemical compound OOC(=O)CCC(=O)OO ADKBGLXGTKOWIU-UHFFFAOYSA-N 0.000 claims description 2
- 229910017052 cobalt Inorganic materials 0.000 claims description 2
- 239000010941 cobalt Substances 0.000 claims description 2
- GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical group [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 claims description 2
- 238000011161 development Methods 0.000 claims description 2
- DDXLVDQZPFLQMZ-UHFFFAOYSA-M dodecyl(trimethyl)azanium;chloride Chemical compound [Cl-].CCCCCCCCCCCC[N+](C)(C)C DDXLVDQZPFLQMZ-UHFFFAOYSA-M 0.000 claims description 2
- 239000004816 latex Substances 0.000 claims description 2
- 229920000126 latex Polymers 0.000 claims description 2
- 229910052938 sodium sulfate Inorganic materials 0.000 claims description 2
- 235000011152 sodium sulphate Nutrition 0.000 claims description 2
- 235000021419 vinegar Nutrition 0.000 claims description 2
- 239000000052 vinegar Substances 0.000 claims description 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 claims 1
- FZGRPBJBMUNMQH-UHFFFAOYSA-N trimethyl-$l^{3}-chlorane Chemical compound CCl(C)C FZGRPBJBMUNMQH-UHFFFAOYSA-N 0.000 claims 1
- 230000013872 defecation Effects 0.000 description 6
- 239000008280 blood Substances 0.000 description 5
- 210000004369 blood Anatomy 0.000 description 5
- 238000010586 diagram Methods 0.000 description 4
- 230000000740 bleeding effect Effects 0.000 description 3
- NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonia chloride Chemical compound [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 description 2
- 150000003278 haem Chemical class 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- INGWEZCOABYORO-UHFFFAOYSA-N 2-(furan-2-yl)-7-methyl-1h-1,8-naphthyridin-4-one Chemical compound N=1C2=NC(C)=CC=C2C(O)=CC=1C1=CC=CO1 INGWEZCOABYORO-UHFFFAOYSA-N 0.000 description 1
- QRSFFHRCBYCWBS-UHFFFAOYSA-N [O].[O] Chemical compound [O].[O] QRSFFHRCBYCWBS-UHFFFAOYSA-N 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 235000019270 ammonium chloride Nutrition 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000000151 deposition Methods 0.000 description 1
- 238000004043 dyeing Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 238000002386 leaching Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 239000013641 positive control Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Hematology (AREA)
- General Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Plasma & Fusion (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
This application discloses a kind of Test paper, which includes ontology, at least one first colour developing block, at least one second colour developing block, and ontology includes being disposed opposite to each other first surface and second surface；First colour developing block is located at the first surface of ontology, for detecting whether hemorrhoid hemorrhage；Second colour developing block is located at the first surface of ontology, for detecting whether enteron aisle internal haemorrhage.The application distinguishes hemorrhoid hemorrhage, enteron aisle internal haemorrhage respectively, therefore utmostly hemorrhoid patients can be avoided to cause unnecessary fear because of false positive by the first colour developing block, the second colour developing block.
Description
Technical field
This application involves the field of medical instrument technology, more particularly to a kind of Test paper.
Background technique
The advantages that Test paper is noninvasive, safe due to its, and patient compliance is substantially improved, become presently the most extensively
The screening for colorectal means suitable for family's self-test.
Present inventor has found that existing Test paper, which can only detect, contains blood in excrement by long-term research
Liquid, and cannot distinguish between as caused by hemorrhoid hemorrhage or enteron aisle internal haemorrhage, it is easy to keep hemorrhoid patients panic due to false positive.
Summary of the invention
The application can distinguish in hemorrhoid hemorrhage and enteron aisle mainly solving the technical problems that provide a kind of Test paper
Blood utmostly avoids hemorrhoid patients from causing unnecessary fear because of false positive.
In order to solve the above technical problems, the technical solution that the application uses is: providing a kind of Test paper, the detection
Test paper includes: ontology, including is disposed opposite to each other first surface and second surface；At least one first colour developing block, positioned at the of ontology
One surface, for detecting whether hemorrhoid hemorrhage；At least one second colour developing block is for detecting positioned at the first surface of ontology
No enteron aisle internal haemorrhage.
The beneficial effect of the application is: being in contrast to the prior art, Test paper provided herein includes this
Body, at least one first colour developing block, at least one second colour developing block, ontology includes being disposed opposite to each other first surface and second surface；
First colour developing block is located at the first surface of ontology, for detecting whether hemorrhoid hemorrhage；Second colour developing block is located at the first table of ontology
Face, for detecting whether enteron aisle internal haemorrhage.The application distinguishes hemorrhoid hemorrhage, intestines by the first colour developing block, the second colour developing block respectively
Road internal haemorrhage, therefore utmostly hemorrhoid patients can be avoided to cause unnecessary fear because of false positive.
Detailed description of the invention
In order to more clearly explain the technical solutions in the embodiments of the present application, make required in being described below to embodiment
Attached drawing is briefly described, it should be apparent that, the drawings in the following description are only some examples of the present application, for
For those of ordinary skill in the art, without creative efforts, it can also be obtained according to these attached drawings other
Attached drawing.Wherein:
Fig. 1 is the structural schematic diagram of one embodiment of the application Test paper；
Fig. 2 is the diagrammatic cross-section of the first colour developing one embodiment of block in Fig. 1；
Fig. 3 is the diagrammatic cross-section of the second colour developing one embodiment of block in Fig. 1；
Fig. 4 is the flow diagram of one embodiment of the application detection method.
Specific embodiment
Below in conjunction with the attached drawing in the embodiment of the present application, technical solutions in the embodiments of the present application carries out clear, complete
Site preparation description, it is clear that described embodiments are only a part of embodiments of the present application, rather than whole embodiments.Based on this
Embodiment in application, those of ordinary skill in the art are obtained every other under the premise of not making creative labor
Embodiment shall fall in the protection scope of this application.
Referring to Fig. 1, Fig. 1 is the structural schematic diagram of one embodiment of the application Test paper.The application Test paper packet
Ontology 10, at least one first colour developing block 11, at least one second colour developing block 12 are included, ontology 10 includes being disposed opposite to each other first surface
101 and second surface (not indicating), the first colour developing block 11 is located at the first surface 101 of ontology 10, for detecting whether hemorrhoid go out
Blood, the second colour developing block 12 is located at the first surface 101 of ontology 10, for detecting whether enteron aisle internal haemorrhage.First colour developing block 11 is set
It is set to circle, in an implement scene, the first colour developing block 11 may be set to be other shapes, such as Fang Huan, rectangle.Second
Colour developing block 12 is set as cross, and in an implement scene, the second colour developing block 12 may be set to be other shapes, such as hook
Shape, exclamation mark shape.In an implement scene, to avoid the first colour developing block 11, second from developing the color block 12 in colour developing, color leaching
Other regions of ontology 10 are contaminated, to reduce the readability of the application Test paper, the first surface 101 of ontology 10 is also covered with
Film.In another implement scene, ontology 10 itself has the characteristic of anti-color dip dyeing.
By above embodiment, the application by first colour developing block 11, second develop the color block 12 distinguish respectively hemorrhoid hemorrhage,
Enteron aisle internal haemorrhage, therefore utmostly hemorrhoid patients can be avoided to cause unnecessary fear because of false positive.
Please continue to refer to Fig. 1, the application Test paper further includes lip ring 13, and lip ring 13 is latex, ring
Shape sealing element 13 is located at the periphery of the first colour developing block 11 and the second colour developing block 12, for protecting the first colour developing block 11 and the second colour developing
Block 12 is not contaminated, and lip ring 13 is set as annular shape shown in FIG. 1, in an implement scene, lip ring 13
It may be configured as other shapes, such as Fang Huanzhuan, in another implement scene, the shape of lip ring 13 and the shape of ontology 10
Unanimously, intermediate to be equipped with a hole, the first colour developing block 11 and the second colour developing block 12 are set for enclosing.It is aobvious that first colour developing block 11 is located at second
The periphery of color lump 12, in an implement scene, the first colour developing block 11 and the second colour developing block 12 can also be oppositely arranged.
Referring to Fig. 2, Fig. 2 is the diagrammatic cross-section of the first colour developing 11 1 embodiment of block in Fig. 1.First colour developing block 11 wraps
Include the first sealer 111, the first color developing agent 112, the first activating agent 113；First sealer 111 is coated with the first color developing agent 112 and first
Activating agent 113, the first sealer 111 are not soluble in water.First sealer 111 is at least in the edge of the first sealer 111 (arrow institute in figure
Refer to) it is fixed with ontology 10.First sealer 111 be equipped at least one dimension D 1 less than the first color developing agent 112 size d1 first
Hole 1111, the quantity of the first hole 1111 are 1,2,3 etc..The shape of first hole 1111 is circle, in other realities
It applies in scene, the shape of the first hole 1111 is rectangular, triangle, and present embodiment does not limit the specific shape of the first hole 1111
Shape；First activating agent 113 is set to the edge of the first sealer 111, and in an implement scene, the first activating agent 113 is set to first
The one side edge of sealer 111, in another implement scene, the first activating agent 113 is set to the both sides of the edge of the first sealer 111.
When the application Test paper investment hemorrhoid hemorrhage patient's defecation after detection container in water when, the first color developing agent 112 due to
The dimension D 1 that its size d1 is greater than the first hole 1111 is deposited in water due to hemorrhoid hemorrhage without escaping from the first sealer 111
In a large amount of hemoglobin, and when the quantity of hemoglobin is greater than first threshold, a large amount of hemoglobin is from the first hole 1111
Middle entrance, to be combined with the first color developing agent 112, the first activating agent 113 adsorbs a large amount of hemoglobins and the first color developing agent 112
In conjunction with assembling the first color developing agent 112 at the first activating agent 113, and then make at the first activating agent 113 and the first sealer 111
Marginal position development.
Wherein, in an implement scene, the quality of the first color developing agent 112 is 5-15g, such as 5g, 8g, 13g, 15g etc..
In other implement scenes, the quality of the first color developing agent 112 can also be particularly configured to other quality according to Special use environment,
It is greater than 15g, or is less than 5g.
First color developing agent 112 is cobalt green, and the first activating agent 113 is lauryl sodium sulfate (SDS), trimethyl
At least one of ammonium chloride (DTAC), dodecyl benzyl dimethyl ammonium chloride (1227).
Referring to Fig. 3, Fig. 3 is the diagrammatic cross-section of the second colour developing 12 1 embodiment of block in Fig. 1.Second colour developing block 12 wraps
Include the second sealer 121, the second color developing agent 122, the second activating agent 123；It is living that second sealer 121 is coated with the second color developing agent 122, second
Property agent 123, the second sealer 121 is not soluble in water, and the second sealer 122 is at least in the edge of the second sealer 122 (arrow signified) and this
Body 10 is fixed.Second sealer 122 is equipped with second hole 1211 of at least one dimension D 2 less than 122 size d2 of the second color developing agent,
The quantity of second hole 1211 is 1,2,3 etc., and the shape of the second hole 1211 is round, rectangular etc., this embodiment party
The shape of the second hole 1211 is not limited in formula；Second activating agent 123 is used to discharge free oxygen under the action of hemoglobin, into
And the second color developing agent 122 is aoxidized, colour developing.Detection after patient's defecation of the Test paper investment enteron aisle internal haemorrhage of the application
When water in container, in water due to a small amount of blood carried in excrement penetrates into and there are a small amount of hemoglobin, hemoglobin is from the
Two holes 1211 enter, so that the heme in hemoglobin makes the second activating agent 123 discharge free oxygen, free oxygen oxygen
Change the second color developing agent 122, so that 122 oxidation stain of the second color developing agent.
Wherein, in an implement scene, the second color developing agent 122 is 3,3', 5,5'- tetramethyl benzidines (TMB), more creates
At least one of the wooden vinegar, Amidopyrine, the second activating agent 123 are phenethyl hydrogen peroxide, peroxysuccinic acid, Peracetic acid
At least one of.
By the above-mentioned means, after defecation due to both hemorrhoid hemorrhage and enteron aisle internal haemorrhage, the blood volume contained in excrement
Difference, the former is much larger than the latter, therefore, after hemorrhoid hemorrhage defecation, the content for the hemoglobin that the water in detection container contains
Larger, a large amount of hemoglobin is located at first activating agent 113 at 111 edge of the first sealer after being combined with the first color developing agent 112
Absorption, and then assemble a large amount of first color developing agent 112 in 111 edge of the first sealer, so that the first colour developing block 11 develops.
And if it is enteron aisle internal haemorrhage defecation after, the content of hemoglobin that the water in detection container contains is less, therefore is not enough to
A large amount of first color developing agent 112 is assembled in the edge of one sealer 111, and the first colour developing block 11 is made to develop, but due to hemoglobin
In the heme that contains be catalyzed the second activating agent 123 so that the second activating agent 123 discharges free oxygen, further oxygen
Change the second color developing agent 122, the second colour developing block 12 develops at this time, and then distinguishes hemorrhoid hemorrhage and enteron aisle internal haemorrhage.
Referring to Fig. 4, Fig. 4 is the flow diagram of one embodiment of the application detection method.This method comprises:
Step S401: positive control is poured into water, and after the first preset time, the application Test paper is put into water
In, waited for the second predetermined time；
In an implement scene, the first preset time is 1 minute, in other implement scenes, the first preset time
It can be 1.5 minutes, 2 minutes etc..Second preset time is 2 minutes, and in other implement scenes, the second predetermined time was 2.5
Minute, 3 minutes etc..
Step S402: judge whether the second colour developing block 12 develops the color；
Step S403: if the second colour developing block 12 does not develop the color, illustrate that Test paper has damaged, and return to above-mentioned steps
S401。
Step S404: if the second colour developing block 12 develops the color, illustrate that Test paper does not damage, by the application Test paper
Put into the water in detection container.
Step S405: judge whether the first colour developing block 11 of Test paper and/or the second colour developing block 12 develop the color；
Step S406: if the first colour developing block 11 of Test paper and/or the second colour developing block 12 develop the color, detection container is replaced
In water, the operation of return step S404；
Patient's excrement is detected in Test paper, before judging patient with the presence or absence of enteron aisle internal haemorrhage or hemorrhoid hemorrhage, is needed
, by executing above-mentioned steps, whether current detection environment, which closes, can determine whether to determine that detection environment is qualified to detection environment investigation
Lattice, if the first colour developing block 11 and/or the second colour developing block 12 develop the color, illustrating to have existed in current detection environment makes first
The substance that colour developing block 11 and/or the second colour developing block 12 develop the color needs to exclude the interference of late detection patient's excrement bring
Detection environment is replaced, i.e. water in replacement detection container, until detecting that there is no make the first colour developing block 11 and/or the in water
Until the substance that two colour developing blocks 12 develop the color.
Step S407: if the first colour developing block 11 and/or the second colour developing block 12 do not develop the color, in detection container after defecation
The application Test paper is put into detection container water；
Step S408: judge whether the first colour developing block 11 and/or the second colour developing block 12 develop the color；
Step S409: if the first colour developing block 11 develops the color, judging there may be hemorrhoid hemorrhage, if the second colour developing block 12
It develops the color, then judges there may be enteron aisle internal haemorrhage, if the first colour developing block 11 and the second colour developing block 12 do not develop the color, judge
Without bleeding；
In an implement scene, in order to make testing result closer to true, or testing result is made more to convince power, it can be with
Implement above-mentioned steps S407-S409 at least once, for example, 2 times, it is 3 inferior.
When step S404-S405 is executed, although there are the feelings that the first colour developing block 11 and the second colour developing block 12 do not develop the color
Condition, it is possible that the case where there are Test paper damages, such as Test paper are rotten.It is led to exclude the presence of above situation
Cause detection deviates or mistake, needs to detect Test paper itself, before executing step S404 to judge test paper
Whether damage, since in actual use, the Conservation environment of Test paper is suitable, therefore, by detecting same batch, Tong Bao
The Test paper of dress can whether there is the case where damaging with Test paper used in primitive decision step S404-S405.
Above-mentioned steps S401-S403, S404-S406, S407-S409 are respectively used to judge whether Test paper is qualified, inspection
Survey whether environment is qualified, whether deposits bleeding.
It wherein, in one embodiment, can also be by judging detect whether environment is qualified, whether Test paper is qualified, is
The no sequence for depositing bleeding corresponding operating executes, without influencing detection effect.
The foregoing is merely presently filed embodiments, are not intended to limit the scope of the patents of the application, all to utilize this
Equivalent structure or equivalent flow shift made by application specification and accompanying drawing content, it is relevant to be applied directly or indirectly in other
Technical field similarly includes in the scope of patent protection of the application.
Claims (10)
1. a kind of Test paper, which is characterized in that the Test paper includes:
Ontology, including it is disposed opposite to each other first surface and second surface；
At least one first colour developing block, positioned at the first surface of the ontology, for detecting whether hemorrhoid hemorrhage；
At least one second colour developing block, positioned at the first surface of the ontology, for detecting whether enteron aisle internal haemorrhage.
2. Test paper according to claim 1, which is characterized in that
The first colour developing block includes the first sealer, the first color developing agent, the first activating agent；
First sealer is coated with first color developing agent and first activating agent, and first sealer is at least described first
The edge of sealer is fixed with the ontology, and first sealer is equipped with second that at least one size is less than first color developing agent
Hole；
First activating agent is set to the edge of first sealer.
3. Test paper according to claim 2, which is characterized in that
First sealer is not soluble in water, and first color developing agent is used to work as hemoglobin present in detection container and is greater than first
When threshold value, the rear edge that first sealer is adsorbed to by first activating agent, makes institute in conjunction with the hemoglobin
State edge development.
4. Test paper according to claim 3, which is characterized in that
The quality of first color developing agent is 5-15 grams.
5. Test paper according to claim 4, which is characterized in that
First color developing agent is cobalt green, and first activating agent is lauryl sodium sulfate (SDS), trimethyl chlorine
Change at least one of ammonium (DTAC), dodecyl benzyl dimethyl ammonium chloride (1227).
6. Test paper according to claim 1, which is characterized in that
The second colour developing block includes the second sealer, the second color developing agent, the second activating agent；
Second sealer is coated with second color developing agent, second activating agent, and second sealer is at least described second
The edge of sealer is fixed with the ontology, and second sealer is equipped with the third that at least one size is less than second color developing agent
Hole；
Second activating agent is used to discharge free oxygen under the action of hemoglobin, and then the second color developing agent is aoxidized, colour developing.
7. Test paper according to claim 6, which is characterized in that
Second sealer is not soluble in water, and second color developing agent is 3,3', 5,5'- tetramethyl benzidines (TMB), guaiaci lignum
At least one of vinegar, Amidopyrine, second activating agent are phenethyl hydrogen peroxide, peroxysuccinic acid, Peracetic acid
At least one of.
8. Test paper according to claim 1, which is characterized in that
The first colour developing block is circular ring shape, and the second colour developing block is cross；And/or
The first colour developing block is located at the periphery of the second colour developing block.
9. Test paper according to claim 1, which is characterized in that the Test paper further include:
Lip ring, positioned at the periphery of the first colour developing block and the second colour developing block, for protecting first colour developing
Block and the second colour developing block be not contaminated.
10. Test paper according to claim 1, which is characterized in that
The lip ring is latex.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811261612.0A CN109444122B (en) | 2018-10-26 | 2018-10-26 | Test paper |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811261612.0A CN109444122B (en) | 2018-10-26 | 2018-10-26 | Test paper |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN109444122A true CN109444122A (en) | 2019-03-08 |
| CN109444122B CN109444122B (en) | 2024-04-12 |
Family
ID=65548770
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811261612.0A Active CN109444122B (en) | 2018-10-26 | 2018-10-26 | Test paper |
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| Country | Link |
|---|---|
| CN (1) | CN109444122B (en) |
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