CN219565981U - Kit for detecting glycosylated albumin in serum - Google Patents
Kit for detecting glycosylated albumin in serum Download PDFInfo
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- CN219565981U CN219565981U CN202320806679.8U CN202320806679U CN219565981U CN 219565981 U CN219565981 U CN 219565981U CN 202320806679 U CN202320806679 U CN 202320806679U CN 219565981 U CN219565981 U CN 219565981U
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- serum
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02W—CLIMATE CHANGE MITIGATION TECHNOLOGIES RELATED TO WASTEWATER TREATMENT OR WASTE MANAGEMENT
- Y02W90/00—Enabling technologies or technologies with a potential or indirect contribution to greenhouse gas [GHG] emissions mitigation
- Y02W90/10—Bio-packaging, e.g. packing containers made from renewable resources or bio-plastics
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Abstract
The utility model relates to a kit for detecting glycosylated albumin in serum, which belongs to the technical field of kits and comprises a box body, wherein a containing cavity is formed in the inner side of the box body, a plurality of test papers can be contained in the inner side of the containing cavity, a plurality of containing grooves are formed in the inner side of the containing cavity, and the containing grooves correspond to the test papers one by one. The utility model solves the problem that the detection test paper of each tested person is not stored in a centralized way independently, which is not beneficial to checking the detection result again in the later period, thereby limiting the application range of the glycosylated albumin detection kit.
Description
Technical Field
The utility model belongs to the technical field of kits, and particularly relates to a kit for detecting glycosylated albumin in serum.
Background
The serum contains a plurality of proteins with different types and functions, the total amount of the proteins in each milliliter of serum is about 60-80mg, the serum proteins are all proteins in the serum, the albumin is the most main component, all proteins have the possibility of saccharification and addition reaction, and after all serum protein components and saccharides undergo saccharification reaction, the human health condition can be detected to a certain extent by detecting the type and the content of the glycosylated albumin in the serum;
the prior patent, the patent application No. CN201821043129.0, a glycosylated serum albumin detection kit, the kit has the characteristics that the kit is aimed at glycosylated serum albumin glycosylation sites and specific monoclonal antibodies of serum albumin non-glycosylation sites, respectively form a double-antibody sandwich structure with glycosylated serum albumin and total serum albumin, has good accuracy and specificity, simultaneously, the kit is convenient and rapid to use, has high sensitivity precision, is not influenced by interference factors such as red blood cell life, hemoglobin structure and the like, can be used for monitoring the average blood sugar level of diabetics for 2-3 weeks, especially gestational diabetes, diabetic nephropathy and hepatic diabetes, and can also be used for screening diabetes, but the kit disclosed by the patent has the same capacity of accommodating detection test paper as other prior glycosylated albumin detection kits, has no structure for additionally setting up independent storage, and because the detection of glycosylated albumin needs multiple times of a time interval, the detection of each person to be detected by the aid of nano fluorescent microsphere is not concentrated and is unfavorable for later-period detection, thereby the detection result of the glycosylated albumin detection kit is limited by the kit, and the detection result of the glycosylated albumin detection kit is used for limiting the range of the glycosylated albumin detection kit.
Disclosure of Invention
The utility model provides a kit for detecting glycosylated albumin in serum, which aims to solve the problems that the kit disclosed in the patent has the capacity of containing detection test paper as other existing glycosylated albumin detection kits, but does not have a structure for independently storing the test paper, and because the detection of glycosylated albumin is carried out for a plurality of times at a certain time interval, if the detection test paper of each detected person is not independently and intensively stored, the later re-checking of the detection result is not facilitated, and the application range of the glycosylated albumin detection kit is limited.
The utility model provides a kit for detecting glycosylated albumin in serum, which comprises a box body, wherein a containing cavity is formed in the inner side of the box body, a plurality of test papers can be contained in the inner side of the containing cavity, a plurality of containing grooves are formed in the inner side of the containing cavity, the containing grooves correspond to the test papers one by one, the corresponding test papers are contained in the containing grooves, one side of each test paper is provided with a instillation table, and the instillation table is cylindrical;
the lower wall surface of the accommodating cavity is provided with a plurality of cover plates which are uniformly distributed, and one end of each cover plate, which is far away from the box body, is fixedly connected with a transverse bar;
the outside of holding tank is covered the closing cap, the outside of closing cap is provided with the pull handle, the outside of closing cap is provided with the tablet of writing, the material of tablet of writing is white cotton paper, the apron is located the outside of closing cap, the apron can cover the front of instillation platform.
Further, the outer edge of the front face of the test paper is provided with a second sealing frame which surrounds the test paper, the thickness of the second sealing frame is smaller than 2mm, and the second sealing frame is made of polyethylene.
By adopting the scheme, the second sealing frame ensures that the liquid on the test paper cannot diffuse out of the test paper.
Further, the jack is seted up to the downside that holds the chamber, draw-in groove four has been seted up at the middle part that holds the chamber, draw-in groove one has been seted up to the upper end that holds the chamber, every draw-in groove one, draw-in groove four and a jack are all distributed respectively in proper order to the both sides of holding the groove, be provided with a fixture block two, two fixture block one and two spliced poles on the closing cap, the both ends of fixture block two are pegged graft with the inboard of two draw-in grooves one respectively, fixture block one and four changeable connections of draw-in groove, grafting pole and the changeable grafting of corresponding jack.
By adopting the scheme, the plugging hole, the clamping groove IV and the clamping groove I enable the sealing cover to be tightly covered on the accommodating groove.
Further, one side of the first clamping block is provided with an expansion block, the expansion block is made of polyurethane, and the expansion block can be clamped with the clamping groove four.
By adopting the scheme, the expansion block can enable the clamping block I to be clamped into the clamping groove IV, so that the sealing cover is tightly covered on the accommodating groove, the test paper and the instillation table are sealed in the accommodating groove, and each test paper is stored independently and respectively.
Further, one end of test paper is provided with the connecting plate two, the one end of connecting plate two is provided with the connecting plate one, the one end of connecting plate one is provided with the cylinder, the inboard that holds the chamber is provided with the connecting rod, connecting rod and cylinder connect soon.
By adopting the scheme, the test paper is indirectly connected to the inner side of the accommodating cavity, so that the test paper can rotate around the connecting rod.
Furthermore, the second connecting plate is provided with easy-to-tear saw-tooth lines, and the second connecting plate is made of double-copper paper.
Through adopting above-mentioned scheme, the easy tearing sawtooth line of connecting plate two makes test paper and connecting plate one, cylinder separation, and then makes the test paper can break away from the inboard that holds the chamber.
Further, a clamping groove II is formed in the top of the first connecting plate, and the clamping groove II is connected with the middle section of the clamping block II in a variable mode.
Through adopting above-mentioned scheme, make connecting plate one obtain the fixed of fixture block two, and then make the position of test paper one end obtain locking.
Further, a first sealing frame is arranged at the outer edge of the accommodating groove, the first sealing frame is U-shaped, the first sealing frame is made of rubber, and the first sealing frame is arranged at the inner side of the accommodating groove.
By adopting the scheme, the sealing frame I is matched with the sealing cover, so that the opening of the inner cavity of the accommodating groove is sealed.
Further, the bottom of the test paper is provided with a bottom plate, the bottom plate is wedge-shaped, and the bottom plate is made of PVC.
Compared with the prior art, the technical scheme provided by the utility model has the following beneficial technical effects:
1. according to the utility model, through the use of the connecting rod, the roller, the accommodating groove and the sealing cover, the first connecting plate can be stored in a concentrated mode and independently, the condition of illness is checked and tracked conveniently in the later period through recording and detecting the condition of the writing board, the first clamping block can be clamped into the fourth clamping groove by the expansion block, the accommodating groove is tightly covered by the sealing cover, the test paper and the instillation platform are sealed in the accommodating groove, and each test paper is stored independently and respectively;
2. according to the utility model, the test paper can be separated from the first connecting plate and the roller through the use of the easy-to-tear saw tooth line of the second connecting plate, so that the test paper can be rapidly separated from the roller.
Additional features and advantages of the utility model will be set forth in the description which follows, and in part will be obvious from the description, or may be learned by practice of the utility model. The objectives and other advantages of the utility model may be realized and attained by the structure particularly pointed out in the written description and drawings.
Drawings
The accompanying drawings are included to provide a further understanding of the utility model and are incorporated in and constitute a part of this specification, illustrate the utility model and together with the embodiments of the utility model, serve to explain the utility model. In the drawings:
FIG. 1 is a schematic top view of the present utility model;
FIG. 2 is a schematic view of the surface structure of the closure of the present utility model;
FIG. 3 is a diagram showing the positional relationship among the first connecting plate, the roller, the second connecting plate and the test paper according to the present utility model;
fig. 4 is a schematic view of a part of the enlarged structure of the portion a in fig. 1 according to the present utility model.
Reference numerals: the box body-1, the accommodating cavity-2, the closing cap-3, the plug hole-4, the instillation area-5, the cover plate-6, the cross bar-7, the writing board-8, the pull handle-9, the connecting plate-10, the connecting rod-11, the roller-12, the clamping groove-13, the test paper-14, the connecting plate-15, the clamping groove-16, the clamping block-17, the clamping block-18, the expansion block-19, the plug post-20, the accommodating groove-21, the sealing frame-22, the clamping groove-23, the sealing frame-24, the easy-tearing saw tooth line-25 and the bottom plate-26.
Detailed Description
In order to make the objects, technical solutions and advantages of the technical solutions of the present utility model more clear, the technical solutions of the embodiments of the present utility model will be clearly and completely described below with reference to the accompanying drawings of specific embodiments of the present utility model. Like reference numerals in the drawings denote like parts. It should be noted that the described embodiments are some, but not all embodiments of the present utility model. All other embodiments, which can be made by a person skilled in the art without creative efforts, based on the described embodiments of the present utility model fall within the protection scope of the present utility model.
As shown in fig. 1-4, the utility model provides a kit for detecting glycosylated albumin in serum, which comprises a box body 1, wherein a containing cavity 2 is formed in the inner side of the box body 1, a plurality of test papers 14 can be contained in the inner side of the containing cavity 2, a plurality of containing grooves 21 are formed in the inner side of the containing cavity 2, the containing grooves 21 are in one-to-one correspondence with the test papers 14, the corresponding test papers 14 are contained in the containing grooves 21, a instillation table 5 is arranged on one side of the test papers 14, and the instillation table 5 is cylindrical;
a plurality of cover plates 6 which are uniformly distributed are arranged on the lower wall surface of the accommodating cavity 2, and a transverse bar 7 is fixedly connected to one end, away from the box body 1, of each cover plate 6;
the outside of holding tank 21 covers closing cap 3, the outside of closing cap 3 is provided with pull handle 9, the outside of closing cap 3 is provided with writing tablet 8, writing tablet 8's material is white cotton paper, apron 6 is located the outside of closing cap 3, apron 6 can cover the front of instillation platform 5.
The outer edge of the front surface of the test paper 14 is provided with a second sealing frame 24 which surrounds the test paper, the thickness of the second sealing frame 24 is smaller than 2mm, and the second sealing frame 24 is made of polyethylene;
the second seal 24 prevents the liquid on the test strip 14 from diffusing out of the test strip 14.
The lower side of the accommodating cavity 2 is provided with a plug hole 4, the middle of the accommodating cavity 2 is provided with a clamping groove IV 23, the upper end of the accommodating cavity 2 is provided with a clamping groove I13, two sides of each accommodating groove 21 are respectively and sequentially provided with a clamping groove I13, a clamping groove IV 23 and a plug hole 4, the sealing cover 3 is provided with a clamping block II 17, two clamping blocks I18 and two plug posts 20, two ends of the clamping block II 17 are respectively plugged with the inner sides of the two clamping grooves I13, the clamping blocks I18 and the clamping grooves IV 23 are in variable connection, and the plug posts 20 and the corresponding plug holes 4 are in variable plugging;
the plugging hole 4, the clamping groove four 23 and the clamping groove one 13 enable the closing cover 3 to tightly cover the containing groove 21.
An expansion block 19 is arranged on one side of the first clamping block 18, the expansion block 19 is made of polyurethane, and the expansion block 19 can be clamped with the fourth clamping groove 23;
the expansion block 19 can enable the first clamping block 18 to be clamped into the fourth clamping groove 23, so that the sealing cover 3 tightly covers the accommodating groove 21, the test paper 14 and the instillation platform 5 are sealed in the accommodating groove 21, and each test paper 14 can be stored independently and respectively.
One end of the test paper 14 is provided with a second connecting plate 15, one end of the second connecting plate 15 is provided with a first connecting plate 10, one end of the first connecting plate 10 is provided with a roller 12, the inner side of the accommodating cavity 2 is provided with a connecting rod 11, and the connecting rod 11 is in screwed connection with the roller 12;
the test paper 14 is indirectly connected to the inside of the housing chamber 2 so that the test paper 14 can rotate around the connecting rod 11.
The second connecting plate 15 is provided with an easy-to-tear saw tooth line 25, and the second connecting plate 15 is made of double-copper paper;
the easy-tearing sawtooth lines 25 of the second connecting plate 15 enable the test paper 14 to be separated from the first connecting plate 10 and the roller 12, and further enable the test paper 14 to be separated from the inner side of the accommodating cavity 2.
A clamping groove II 16 is formed in the top of the first connecting plate 10, and the clamping groove II 16 is in variable connection with the middle section of the clamping block II 17;
the first connecting plate 10 is fixed by the second clamping block 17, and the position of one end of the test paper 14 is locked.
The outer edge of the accommodating groove 21 is provided with a first sealing frame 22, the first sealing frame 22 is U-shaped, the first sealing frame 22 is made of rubber, and the first sealing frame 22 is arranged on the inner side of the accommodating groove 21;
the first sealing frame 22 is matched with the closing cover 3 to close the opening of the inner cavity of the accommodating groove 21.
The bottom of the test paper 14 is provided with a bottom plate 26, the bottom plate 26 is wedge-shaped, and the bottom plate 26 is made of PVC;
the bottom plate 26 tilts the test strip 14 so that the drip station 5 is higher than the second connection plate 15.
A fluorescent bonding pad is arranged on the outer side of the middle part of the test paper 14;
the fluorescent binding pad is provided with a coating hs-CRP antibody-nano fluorescent microsphere compound;
the test paper 14 is arranged on the outer side, close to the first connecting plate 10, of the test paper and is provided with aldehyde red fluorescent microspheres, and the particle size of the nano fluorescent microspheres is 120-190 nm;
the excitation wavelength of the nano fluorescent microsphere is 365nm, the emission wavelength is 611-616 nm, and the content of aldehyde groups on the surface is 0.2-0.4 mmol/g.
The material of the test paper 14 is nitrocellulose membrane.
The implementation mode specifically comprises the following steps: one of the closing caps 3 is uncovered, so that the containing groove 21 is opened, the cover plate 6 is turned over, the closing cap 3 is exposed, 60ul of serum is taken out by a liquid dispenser, and the serum is dripped on the instillation table 5, so that the closing cap 3 can detect the glycosylated albumin in the serum;
covering the instillation table 5 by the sealing cover 3, spreading serum on the test paper 14 until the serum contacts nano fluorescent microsphere particles, wherein the place is set as a place A, the end part of the test paper 14 far away from the instillation table 5 and the place A is set as a place B, when the place B develops color, the place B is observed in a handheld fluorescence reader (immunofluorescence quantitative analyzer) after 10min, and the content of glycosylated albumin in the serum is judged by judging the color development condition of the place A;
then, the time, content, and serial number of the test are written on the tablet 8, and the test paper 14 is sealed and stored by covering the storage groove 21 with the closing cap 3.
The foregoing has shown and described the basic principles and main features of the present utility model and the advantages of the present utility model. It will be understood by those skilled in the art that the present utility model is not limited to the embodiments described above, and that the above embodiments and descriptions are merely illustrative of the principles of the present utility model, and various changes and modifications may be made without departing from the spirit and scope of the utility model, which is defined in the appended claims. The scope of the utility model is defined by the appended claims and equivalents thereof.
Claims (9)
1. The utility model provides a kit for saccharification albumin detects in serum, includes box body (1), its characterized in that, accommodating cavity (2) has been seted up to the inboard of box body (1), accommodating cavity (2) inboard can hold a plurality of test paper (14), accommodating cavity (2) inboard has been seted up a plurality of holding tanks (21), holding tanks (21) and test paper (14) one-to-one, holding tanks (21) hold corresponding test paper (14), one side of test paper (14) is provided with instillation platform (5), instillation platform (5) shape is the cylinder;
the lower wall surface of the accommodating cavity (2) is provided with a plurality of cover plates (6) which are uniformly distributed, and one end, far away from the box body (1), of each cover plate (6) is fixedly connected with a transverse bar (7);
the outside of holding tank (21) is covered closing cap (3), the outside of closing cap (3) is provided with pull handle (9), the outside of closing cap (3) is provided with and writes tablet (8), the material of writing tablet (8) is white cotton paper, apron (6) are located the outside of closing cap (3), apron (6) can cover the front of instillation platform (5).
2. A kit for the detection of glycated albumin in serum as claimed in claim 1, wherein: the outer edge of the front face of the test paper (14) is provided with a second sealing frame (24) which surrounds the test paper, the thickness of the second sealing frame (24) is smaller than 2mm, and the second sealing frame (24) is made of polyethylene.
3. A kit for the detection of glycated albumin in serum as claimed in claim 1, wherein: the utility model discloses a plug hole (4) has been seted up to the downside that holds chamber (2), draw-in groove four (23) have been seted up at the middle part that holds chamber (2), draw-in groove one (13) have been seted up to the upper end that holds chamber (2), every draw-in groove (21) both sides have all distributed a draw-in groove one (13), a draw-in groove four (23) and a spliced eye (4) respectively in proper order, be provided with a fixture block two (17), two fixture blocks one (18) and two spliced poles (20) on closing cap (3), the both ends of fixture block two (17) are pegged graft with the inboard of two draw-in grooves one (13) respectively, fixture block one (18) and draw-in groove four (23) are variably connected, spliced pole (20) and corresponding spliced hole (4) are variably pegged graft.
4. A kit for the detection of glycated albumin in serum as claimed in claim 3, wherein: one side of the clamping block I (18) is provided with an expansion block (19), the expansion block (19) is made of polyurethane, and the expansion block (19) can be clamped with the clamping groove IV (23).
5. A kit for the detection of glycated albumin in serum as claimed in claim 3, wherein: one end of test paper (14) is provided with connecting plate two (15), the one end of connecting plate two (15) is provided with connecting plate one (10), the one end of connecting plate one (10) is provided with cylinder (12), the inboard that holds chamber (2) is provided with connecting rod (11), connecting rod (11) and cylinder (12) connect soon.
6. The kit for detecting glycated albumin in serum as claimed in claim 5, wherein: the second connecting plate (15) is provided with an easy-to-tear saw tooth line (25), and the second connecting plate (15) is made of double-copper paper.
7. The kit for detecting glycated albumin in serum as claimed in claim 5, wherein: the top of the first connecting plate (10) is provided with a second clamping groove (16), and the second clamping groove (16) is connected with the middle section of the second clamping block (17) in a variable mode.
8. A kit for the detection of glycated albumin in serum as claimed in claim 1, wherein: the inner side of the accommodating cavity (2) is close to the outer edge of the accommodating groove (21), a first sealing frame (22) is arranged, the first sealing frame (22) is U-shaped, and the first sealing frame (22) is made of rubber.
9. The kit for detecting glycated albumin in serum as claimed in claim 5, wherein: the bottom of test paper (14) is provided with bottom plate (26), bottom plate (26) are wedge.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202320806679.8U CN219565981U (en) | 2023-04-12 | 2023-04-12 | Kit for detecting glycosylated albumin in serum |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202320806679.8U CN219565981U (en) | 2023-04-12 | 2023-04-12 | Kit for detecting glycosylated albumin in serum |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN219565981U true CN219565981U (en) | 2023-08-22 |
Family
ID=87669571
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202320806679.8U Active CN219565981U (en) | 2023-04-12 | 2023-04-12 | Kit for detecting glycosylated albumin in serum |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN219565981U (en) |
-
2023
- 2023-04-12 CN CN202320806679.8U patent/CN219565981U/en active Active
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