CN211263196U - Photochemical test card capable of removing endogenous interfering substances - Google Patents
Photochemical test card capable of removing endogenous interfering substances Download PDFInfo
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- CN211263196U CN211263196U CN201922324525.1U CN201922324525U CN211263196U CN 211263196 U CN211263196 U CN 211263196U CN 201922324525 U CN201922324525 U CN 201922324525U CN 211263196 U CN211263196 U CN 211263196U
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Abstract
The utility model discloses a photochemistry test card with get rid of endogenous interfering substance, test card epitheca, set up the application of sample hole on the test card epitheca, set up the diffusion barrier under the test card epitheca, set up the first layer of straining blood under the diffusion barrier, set up the second layer of straining blood under the first layer of straining blood, set up the reaction membrane under the second layer of straining blood, set up the single face glue under the reaction membrane, set up the test card inferior valve under the single face glue, set up main test hole and the reference test hole on the test card inferior valve; the utility model discloses set up a reaction contrast region, the concentration that obtains with the main test hole detection subtracts the contrast test hole and detects is actual material concentration to more accurate detection goes out the concentration of this material.
Description
Technical Field
The utility model relates to a detection area, especially a photochemistry test card.
Background
Photochemical reaction is also called photochemical reaction, and refers to a chemical reaction of a substance due to the action of light. I.e., a chemical reaction that occurs when a substance absorbs light energy under irradiation of visible light or ultraviolet light. Photochemical test cards are test cards that utilize such principles.
The blood fat test card is the test card for measuring blood fat, the test card in the market can not remove endogenous interfering substances, when testing substances such as creatinine, glutamic-pyruvic transaminase or glutamic-oxalacetic transaminase, the existing method is basically not feasible, although the gradient can be tested, the interference is too large because the sample contains intermediate substances of the reaction, the creatine, pyruvic acid and other substances exist in the blood, the inaccurate market for detecting the creatinine, the glutamic-pyruvic transaminase or the glutamic-oxalacetic transaminase in the blood by the method needs a photochemical test card which can eliminate the interference of the original creatine, the pyruvic acid and other substances in the sample, thereby obtaining a more accurate test result, and the utility model solves the problems.
SUMMERY OF THE UTILITY MODEL
For solving prior art's not enough, the utility model aims to provide a photochemistry test card with get rid of endogenous interfering substance, the utility model discloses set up a reaction contrast region, the concentration that obtains the concentration that detects the main test hole subtracts the contrast test hole and detects is actual material concentration to more accurate detection goes out the concentration of this material.
In order to achieve the above object, the utility model adopts the following technical scheme:
the utility model provides a photochemistry test card with get rid of endogenous interfering substance, the test card epitheca, set up the application of sample hole on the test card epitheca, set up the diffusion barrier under the test card epitheca, set up the first layer of straining blood under the diffusion barrier, set up the second layer of straining blood under the first layer of straining blood, set up the reaction membrane under the second layer of straining blood, set up the single face that sets up under the reaction membrane and glue, set up the test card inferior valve under the single face is glued, set up main test hole and the control test hole on the test card inferior valve.
In the photochemical test card for removing the endogenous interfering substances, two through holes corresponding to the main test hole and the contrast test hole are formed in the single-sided adhesive.
In the photochemical test card for removing the endogenous interfering substances, the reaction membrane and the second blood filtering layer are respectively and correspondingly arranged at the positions of the two through holes.
In the photochemical test card for removing endogenous interfering substances, the diffusion membrane is a PES diffusion membrane.
The photochemical test card for removing endogenous interfering substances comprises a first blood filter layer and a second blood filter layer, wherein the first blood filter layer comprises: modified polysulfone membrane, nylon membrane, polypropylene filter membrane, filter paper, glass fiber filter membrane and nitrocellulose blood filter layer.
The photochemical test card for removing endogenous interfering substances comprises a second blood filter layer and a second light-emitting layer, wherein the second light-emitting layer comprises: modified polysulfone membrane, nylon membrane, polypropylene filter membrane, filter paper, glass fiber filter membrane and nitrocellulose blood filter layer.
The photochemical test card for removing endogenous interfering substances comprises the following reaction membranes: polysulfone membranes, nylon membranes.
The photochemical test card for removing endogenous interfering substances comprises the following components: polyvinyl chloride single-sided adhesive, polycarbonate single-sided adhesive, polyesteramide single-sided adhesive and polyester single-sided adhesive.
The utility model discloses an useful part lies in:
the structure design of the utility model forms a siphon automatic sample adding structure;
the utility model is provided with the diffusion layer and the blood filtering layer, so that blood can uniformly and rapidly infiltrate into the reaction area;
two reaction areas, a conventional test area and a control test area are arranged below the blood filtration layer, and the actual substance concentration is obtained by adding, subtracting and subtracting test results of the two areas, so that the detection accuracy is improved.
Drawings
FIG. 1 is an exploded view of one embodiment of the present invention;
fig. 2 is a cross-sectional view of an embodiment of the present invention.
The meaning of the reference symbols in the figures:
the test card comprises a lower shell of a test card 100, a main test hole 101, a reference test hole 102, a single-sided adhesive 200, reaction membranes 301 and 302, second blood filtration layers 401 and 402, a first blood filtration layer 501, a diffusion membrane 601, an upper shell of a test card 700 and a sample adding hole 701.
Detailed Description
The present invention will be described in detail with reference to the accompanying drawings and specific embodiments.
As shown in fig. 1 and 2, a photochemical test card for removing endogenous interferents includes a test card upper case 700, a sample application hole 701 disposed on the test card upper case 700, a diffusion membrane 601 disposed under the test card upper case 700, a first blood filtration layer 501 disposed under the diffusion membrane 601, second blood filtration layers 401 and 402 disposed under the first blood filtration layer 501, reaction membranes 301 and 302 disposed under the second blood filtration layers 401 and 402, a single-sided adhesive 200 disposed under the reaction membranes 301 and 302, a test card lower case 100 disposed under the single-sided adhesive 200, a main test hole 101 disposed on the test card lower case 100, and a reference test hole 102. The structure design of the utility model forms a siphon automatic sample adding structure; the utility model is provided with the diffusion layer and the blood filtering layer, so that blood can uniformly and rapidly infiltrate into the reaction area; two reaction areas, a conventional test area and a control test area are arranged below the blood filtration layer, and the actual substance concentration is obtained by adding, subtracting and subtracting test results of the two areas, so that the detection accuracy is improved.
The single-sided adhesive 200 is provided with two through holes corresponding to the main test hole 101 and the control test hole 102, and two reaction membranes 301 and 302 and two second blood filter layers 401 and 402 are respectively arranged at the positions of the two through holes.
Materials that can be selected for each layer: the diffusion film 601 is a PES diffusion film 601; the first blood filter layer 501 includes: modified polysulfone membrane, nylon membrane, polypropylene filter membrane, filter paper, glass fiber filter membrane and nitrocellulose blood filter layer; the second hemofilter layers 401, 402 include: modified polysulfone membrane, nylon membrane, polypropylene filter membrane, filter paper, glass fiber filter membrane and nitrocellulose blood filter layer; the reaction membranes 301, 302 include: polysulfone membranes, nylon membranes; the single-sided adhesive 200 includes: polyvinyl chloride single-sided adhesive, polycarbonate single-sided adhesive, polyesteramide single-sided adhesive, polyester single-sided adhesive; it should be noted that: the material is not restricted, as long as can reach such function and be applicable to the utility model discloses a material of structure is all in the protection scope of the utility model.
As an example, the single-sided adhesive 200 is made of polycarbonate; the reaction membrane 301 is fixed with creatininase, creatine hydrolase, sarcosine oxidase, horseradish peroxidase and other reaction substances; the reaction membrane 302 is fixed with creatine hydrolase, sarcosine oxidase, horseradish peroxidase and other reaction substances; the second blood filter layer 401 or 402 is a nitrocellulose blood filter layer; the first blood filtering layer 501 is a nitrocellulose blood filtering layer; the diffusion membrane 601 is a hydrophilic PES membrane, when a sample is dripped through the sample adding hole 701, the sample is uniformly distributed in the sample through the hydrophilic layer, then the sample is uniformly infiltrated downwards through the blood filtering layer, the signal value detected through the area is mainly the concentration C2 of endogenous creatine due to the fact that no creatininase exists in the reaction membrane 302, the concentration C1 of the total concentration of creatinine and endogenous creatine in the sample is detected through the reaction membrane 301, and finally the concentration of creatinine in the sample is obtained through C1-C2 through an instrument. The method can remove the interference of endogenous creatine, so that the result is more ready, misdiagnosis is avoided, and the clinical effect can be achieved.
As another example, the single-sided adhesive 200 is made of polycarbonate; the reaction membrane 301 is fixed with L-alanine, pyruvate oxidase, alpha-ketoglutaric acid, peroxidase and other reaction substances; the reaction membrane 302 is fixed with pyruvate oxidase, alpha-ketoglutaric acid, peroxidase and other reaction substances; the second blood filter layer 401 or 402 is a nitrocellulose blood filter layer; the first blood filtering layer 501 is a nitrocellulose blood filtering layer; the diffusion membrane 601 is a hydrophilic PES membrane, when a sample is dripped through the sample adding hole 701, the sample is uniformly distributed in the sample through the hydrophilic layer, then the sample is uniformly infiltrated downwards through the blood filtering layer, because the reaction membrane 302 does not contain L-alanine, the signal value detected through the area is mainly the concentration C2 of endogenous pyruvic acid, then the concentration C1 of the total of glutamic-pyruvic transaminase and endogenous pyruvic acid in the sample is detected through the reaction membrane 301, and finally the concentration of the glutamic-pyruvic transaminase in the sample is obtained through C1-C2 by an instrument. The method can remove the interference of endogenous pyruvic acid, so that the result is more prepared, misdiagnosis is avoided, and the clinical effect can be achieved.
The utility model provides a photochemistry test card with get rid of endogenous interfering substance, the utility model discloses set up a reaction contrast region, the concentration that subtracts contrast test hole 102 detection with the concentration that main test hole 101 detected and obtain is actual material concentration to more accurate detection goes out the concentration of this material.
The foregoing illustrates and describes the principles, general features, and advantages of the present invention. It should be understood by those skilled in the art that the above embodiments do not limit the present invention in any way, and all technical solutions obtained by adopting equivalent replacement or equivalent transformation fall within the protection scope of the present invention.
Claims (8)
1. The utility model provides a photochemistry test card with get rid of endogenous interfering substance, its characterized in that, the test card epitheca, set up in application of sample hole on the test card epitheca, set up in diffusion barrier under the test card epitheca, set up in the first blood layer of straining under the diffusion barrier, set up in the second blood layer of straining under the first blood layer of straining sets up in the reaction membrane under the second blood layer of straining, set up in single face under the reaction membrane is glued, set up in the test card inferior valve that single face was glued down, set up in main test hole and control test hole on the test card inferior valve.
2. The photochemical test card for removing endogenous interference substances according to claim 1, wherein two through holes corresponding to the main test hole and the control test hole are provided on the single-sided adhesive.
3. The photochemical test card for removing endogenous interference substances as claimed in claim 2, wherein there are two reaction membranes and two second blood filter layers, each of which is disposed at the position of two through holes.
4. The photochemical test card for removing endogenous interference substances according to claim 1, wherein the diffusion membrane is a PES diffusion membrane.
5. The photochemical test card for removing endogenous interferent substance according to claim 1, wherein the first hemofilter layer comprises: modified polysulfone membrane, nylon membrane, polypropylene filter membrane, filter paper, glass fiber filter membrane and nitrocellulose blood filter layer.
6. The photochemical test card for removing endogenous interferent substance according to claim 1, wherein the second layer of blood filter comprises: modified polysulfone membrane, nylon membrane, polypropylene filter membrane, filter paper, glass fiber filter membrane and nitrocellulose blood filter layer.
7. The photochemical test card for removing endogenous interference substances according to claim 1, wherein the reaction membrane comprises: polysulfone membranes, nylon membranes.
8. The photochemical test card for removing endogenous interference substances according to claim 1, wherein the single-sided glue comprises: polyvinyl chloride single-sided adhesive, polycarbonate single-sided adhesive, polyesteramide single-sided adhesive and polyester single-sided adhesive.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201922324525.1U CN211263196U (en) | 2019-12-23 | 2019-12-23 | Photochemical test card capable of removing endogenous interfering substances |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201922324525.1U CN211263196U (en) | 2019-12-23 | 2019-12-23 | Photochemical test card capable of removing endogenous interfering substances |
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| CN211263196U true CN211263196U (en) | 2020-08-14 |
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| CN201922324525.1U Active CN211263196U (en) | 2019-12-23 | 2019-12-23 | Photochemical test card capable of removing endogenous interfering substances |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111197071A (en) * | 2020-01-10 | 2020-05-26 | 杭州联晟生物科技有限公司 | Test card for detecting glutamic-pyruvic transaminase by photochemical method and preparation method thereof |
| CN113075142A (en) * | 2021-03-31 | 2021-07-06 | 长沙中生众捷生物技术有限公司 | Creatinine test strip and application thereof |
| CN116754341A (en) * | 2023-05-17 | 2023-09-15 | 重庆云芯医联科技有限公司 | Detection card for simultaneous detection of glutamic-pyruvic transaminase and glutamic-oxalacetic transaminase and preparation method thereof |
-
2019
- 2019-12-23 CN CN201922324525.1U patent/CN211263196U/en active Active
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111197071A (en) * | 2020-01-10 | 2020-05-26 | 杭州联晟生物科技有限公司 | Test card for detecting glutamic-pyruvic transaminase by photochemical method and preparation method thereof |
| CN113075142A (en) * | 2021-03-31 | 2021-07-06 | 长沙中生众捷生物技术有限公司 | Creatinine test strip and application thereof |
| CN113075142B (en) * | 2021-03-31 | 2023-10-03 | 复星诊断科技(长沙)有限公司 | Creatinine test strip and application thereof |
| CN116754341A (en) * | 2023-05-17 | 2023-09-15 | 重庆云芯医联科技有限公司 | Detection card for simultaneous detection of glutamic-pyruvic transaminase and glutamic-oxalacetic transaminase and preparation method thereof |
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