JP6290221B2 - デスモグレイン2(dsg2)結合タンパク質およびその使用 - Google Patents
デスモグレイン2(dsg2)結合タンパク質およびその使用 Download PDFInfo
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- JP6290221B2 JP6290221B2 JP2015533277A JP2015533277A JP6290221B2 JP 6290221 B2 JP6290221 B2 JP 6290221B2 JP 2015533277 A JP2015533277 A JP 2015533277A JP 2015533277 A JP2015533277 A JP 2015533277A JP 6290221 B2 JP6290221 B2 JP 6290221B2
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- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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- C12N2710/10033—Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory
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- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10333—Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- Health & Medical Sciences (AREA)
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- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Endocrinology (AREA)
- Dermatology (AREA)
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- Oncology (AREA)
- Communicable Diseases (AREA)
- General Engineering & Computer Science (AREA)
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- Urology & Nephrology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261705523P | 2012-09-25 | 2012-09-25 | |
| US61/705,523 | 2012-09-25 | ||
| PCT/US2013/061431 WO2014052322A1 (en) | 2012-09-25 | 2013-09-24 | Desmoglein 2 (dsg2) binding proteins and uses therefor |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015532265A JP2015532265A (ja) | 2015-11-09 |
| JP2015532265A5 JP2015532265A5 (https=) | 2016-10-20 |
| JP6290221B2 true JP6290221B2 (ja) | 2018-03-07 |
Family
ID=49293927
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015533277A Active JP6290221B2 (ja) | 2012-09-25 | 2013-09-24 | デスモグレイン2(dsg2)結合タンパク質およびその使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20150246949A1 (https=) |
| EP (1) | EP2900818B1 (https=) |
| JP (1) | JP6290221B2 (https=) |
| KR (1) | KR102175034B1 (https=) |
| CN (2) | CN105008535B (https=) |
| AU (1) | AU2013323775B2 (https=) |
| WO (1) | WO2014052322A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11201507393TA (en) | 2013-03-14 | 2015-10-29 | Salk Inst For Biological Studi | Oncolytic adenovirus compositions |
| KR102608590B1 (ko) | 2014-09-24 | 2023-12-01 | 솔크 인스티튜트 포 바이올로지칼 스터디즈 | 종양 살상 바이러스 및 이의 사용방법 |
| WO2017147269A1 (en) | 2016-02-23 | 2017-08-31 | Salk Institute For Biological Studies | Exogenous gene expression in therapeutic adenovirus for minimal impact on viral kinetics |
| WO2017147265A1 (en) | 2016-02-23 | 2017-08-31 | Salk Institute For Biological Studies | High throughput assay for measuring adenovirus replication kinetics |
| US10836823B2 (en) | 2016-06-06 | 2020-11-17 | Asclepiumm Taiwan Co., Ltd. | Dsg2 monoclonal antibody and the applications thereof |
| JP7112753B2 (ja) * | 2016-06-06 | 2022-08-04 | アスクリピウム タイワン シーオー., エルティーディー. | Dsg2由来ペプチド |
| EP3532082A4 (en) | 2016-12-12 | 2020-08-26 | Salk Institute for Biological Studies | SYNTHETIC ADENOVIRUS TUMOR TARGETING AND THEIR USES |
| EP3743090A4 (en) * | 2018-01-25 | 2022-02-09 | Pai Life Sciences, Inc. | CONJUGABLE DESMOGLEIN 2 (DSG2)-BINDING PROTEINS AND USES THEREOF |
| CN112292449A (zh) | 2018-04-09 | 2021-01-29 | 萨克生物研究学院 | 具有增强的复制特性的溶瘤腺病毒组合物 |
| CN111879940B (zh) * | 2020-04-28 | 2022-02-01 | 中国科学院微生物研究所 | 肺结核标志物及应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5211657A (en) | 1988-11-07 | 1993-05-18 | The United States Government As Represented By The Secretary Of The Department Of Health And Human Services | Laminin a chain deduced amino acid sequence, expression vectors and active synthetic peptides |
| US6455314B1 (en) * | 1998-09-11 | 2002-09-24 | Genvec, Inc. | Alternatively targeted adenovirus |
| AU783879B2 (en) * | 1999-11-25 | 2005-12-15 | Transgene S.A. | Modified adenovirus fibre and uses |
| SG98393A1 (en) | 2000-05-19 | 2003-09-19 | Inst Materials Research & Eng | Injectable drug delivery systems with cyclodextrin-polymer based hydrogels |
| US6635466B2 (en) * | 2001-01-09 | 2003-10-21 | University Of Iowa Research Foundation | Adenovirus serotype 30 (Ad30) |
| ES2601143T3 (es) | 2002-07-19 | 2017-02-14 | Omeros Corporation | Copolímeros tribloque biodegradables, métodos de síntesis de los mismos, e hidrogeles y biomateriales preparados a partir de los mismos |
| WO2004063355A2 (en) * | 2003-01-10 | 2004-07-29 | Protein Design Labs, Inc. | Novel methods of diagnosis of metastatic cancer, compositions and methods of screening for modulators of matastatic cancer |
| CN101068933A (zh) * | 2004-08-25 | 2007-11-07 | 细胞基因系统有限公司 | 用于肿瘤细胞增强转导的纤维修饰的腺病毒载体 |
| KR101915699B1 (ko) * | 2010-06-10 | 2018-11-06 | 유니버시티 오브 워싱톤 스루 이츠 센터 포 커머셜리제이션 | 데스모글레인 2(디에스쥐2)와 아데노바이러스의 상호작용을 위한 방법 및 시스템 |
-
2013
- 2013-09-24 EP EP13771350.9A patent/EP2900818B1/en active Active
- 2013-09-24 AU AU2013323775A patent/AU2013323775B2/en active Active
- 2013-09-24 CN CN201380060698.XA patent/CN105008535B/zh active Active
- 2013-09-24 KR KR1020157010265A patent/KR102175034B1/ko active Active
- 2013-09-24 WO PCT/US2013/061431 patent/WO2014052322A1/en not_active Ceased
- 2013-09-24 US US14/429,705 patent/US20150246949A1/en not_active Abandoned
- 2013-09-24 CN CN201811167962.0A patent/CN109796524A/zh active Pending
- 2013-09-24 JP JP2015533277A patent/JP6290221B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| KR20150058463A (ko) | 2015-05-28 |
| US20150246949A1 (en) | 2015-09-03 |
| AU2013323775B2 (en) | 2018-10-18 |
| EP2900818A1 (en) | 2015-08-05 |
| AU2013323775A1 (en) | 2015-04-09 |
| WO2014052322A1 (en) | 2014-04-03 |
| CN109796524A (zh) | 2019-05-24 |
| EP2900818B1 (en) | 2017-06-07 |
| JP2015532265A (ja) | 2015-11-09 |
| CN105008535B (zh) | 2018-10-16 |
| CN105008535A (zh) | 2015-10-28 |
| KR102175034B1 (ko) | 2020-11-06 |
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