JP6266980B2 - ヒドロゲルジャケット付きステント - Google Patents
ヒドロゲルジャケット付きステント Download PDFInfo
- Publication number
- JP6266980B2 JP6266980B2 JP2013533908A JP2013533908A JP6266980B2 JP 6266980 B2 JP6266980 B2 JP 6266980B2 JP 2013533908 A JP2013533908 A JP 2013533908A JP 2013533908 A JP2013533908 A JP 2013533908A JP 6266980 B2 JP6266980 B2 JP 6266980B2
- Authority
- JP
- Japan
- Prior art keywords
- stent
- hydrogel
- frame
- jacketed
- stent frame
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0014—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0057—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof stretchable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0061—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof swellable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2220/0025—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
- A61F2220/005—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements using adhesives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2220/0025—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
- A61F2220/0058—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements soldered or brazed or welded
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0003—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having an inflatable pocket filled with fluid, e.g. liquid or gas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0069—Sealing means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0096—Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers
- A61F2250/0098—Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers radio-opaque, e.g. radio-opaque markers
Description
本出願は、参照により本明細書に組み込まれる「Hydrogel Jacketed Stents」と題する、2010年10月11日に出願された同時係属米国仮特許出願第61/391,736号明細書に対する優先権を主張する。
ヒドロゲルジャケット付きステントは、ステントの適切な拡張を可能にするとともに、ステントフレームに対するカバーも提供する。ヒドロゲルジャケットを、ステント留置中にヒドロゲルジャケットに著しい損傷をもたらすことなくステントの拡張を可能にするように、ステントの外側に取り付けることができる。特に、ステントの拡張が広すぎず、ヒドロゲルが十分に柔軟である(compliant)場合、ヒドロゲルを拡張していないステントフレームの上に、留置後の拡張したステントを著しく引裂くことなく覆うように十分膨張するように、巻き付けることができる。さらなる実施形態では、ジャケットを、ひだ状にするか、折り重ねるか、巻き付けるかまたは他の方法で取り付けることができ、それにより、ヒドロゲルジャケットは、ステントが留置される時、可能性として幾分か伸張して、少なくとも部分的に展開することができる。ステントフレームの上でのヒドロゲルジャケットの膨潤により、ステントフレームを少なくとも幾分か封入することができ、それにより脈管を通る流れのステントフレームとの接触を低減するかまたはなくすことができる。ヒドロゲルが十分に膨潤することにより、ヒドロゲルのカバーまたはジャケットのみを使用してステントを有効に覆うことができる。いくつかの実施形態では、ヒドロゲルは、選択された薬剤または薬剤の組合せを溶出することができる。
概して、ヒドロゲルジャケット付きステントの送達を、従来のステントの送達に非常に類似して行うことができる。送達カテーテルの遠位端が、たとえば止血弁、取付具、イントロデューサ、ガイドカテーテル等のうちの1つまたは複数を使用して、患者内に導入される。そして、ステントを、脈管内の狭窄に近接して配置することができる。ステントの送達を、バルーン、あるいは適切に作動される他の機械的拡張要素の拡張により、またはシースあるいは他の制約からの自己拡張型器具の放出により、達成することができる。特定の拡張力および拡張の速度を、ステントフレームおよびヒドロゲルジャケットに対して適切であるように選択することができる。いくつかの実施形態では、ヒドロゲルジャケット付きステントを、ステント留置の前の期間に脈管の流体に露出させることにより、留置の前にヒドロゲルのさらなる水和を可能にすることができる。
Claims (8)
- 拡張可能なステントフレームであり、前記ステントフレームが開放構造を有しており、
前記ステントフレームによって画定される外面および直径がその初期形態の少なくとも約
2倍を超える拡張可能な形態を有するステントフレームと、前記ステントフレームがその
拡張形態まで拡張した時にヒドロゲルシートが前記ステントフレームの上に直接ジャケッ
トを形成するように、前記ステントフレームの前記外面に関連するヒドロゲルシートとを
具備する、体管内に配置されるジャケット付きステントであって、前記ヒドロゲルシート
は未水和の状態では前記ステントフレームの外面のみに接触し、そして前記ヒドロゲルシ
ートは、水溶性流体内で、膨張したヒドロゲルシートが水性環境において前記拡張したス
テントの内面を少なくとも部分的に覆うような厚さを有しかつそのように拡張し、ヒドロ
ゲルシートが、厚さ約0.001mmから約0.5mmを有し、そして前記ヒドロゲルが
、水性環境に露出されると、その初期厚さに対して厚さが少なくとも約1.5倍膨潤する
、ジャケット付きステント。 - 前記ステントフレームの拡張した直径の前記ステントフレームの拡張していない直径に
対する比率が、約2から約6である、請求項1に記載のジャケット付きステント。 - 前記ステントフレームが金属を含み、前記ヒドロゲルシートが、ポリウレタン、ポリア
クリル酸およびそのエステル、ポリメタクリル酸およびそのエステル、ポリアクリロニト
リル、ポリエチレングリコールおよびその誘導体、ポリアクリルアミド、エポキシポリマ
ー、それらのコポリマーまたはそれらの混合物を含む、請求項1に記載のジャケット付き
ステント。 - ヒドロゲルシートが、前記ステントフレームの端部の部分を除き前記ステントフレーム
の外面を覆っている、請求項1に記載のジャケット付きステント。 - ヒドロゲルシートが、前記ステントフレームの一部を覆わず、前記ジャケット付きステ
ントが、前記ステントの前記覆われていない部分を示す放射線不透過性マーカをさらに具
備する、請求項1に記載のジャケット付きステント。 - 送達カテーテルと、前記送達カテーテルによって支持された送達アクチュエータと、請
求項1に記載のジャケット付きステントであって、脈管内の前記ステントの留置を制御す
る前記送達アクチュエータに動作可能に接続されたジャケット付きステントとを具備する
医療器具。 - 前記送達アクチュエータが、前記送達カテーテルに対して摺動するシースを備え、前記
送達シースが、前記ステントが前記送達カテーテルと前記シースとの間に制約される形態
と、前記ステントが制約されない形態とを有し、前記ステントが自己拡張型である、請求
項6に記載の医療器具。 - 前記送達アクチュエータがバルーンを備え、前記バルーンが、前記バルーンの膨張によ
り前記ステントが拡張するように前記送達カテーテルに配置されており、前記送達カテー
テルが、流体貯蔵器に動作可能に接続されたバルーン流路をさらに備え、それにより、前
記貯蔵器からの流体を、前記バルーンを膨張させるように制御された方法で搬送すること
ができる、請求項6に記載の医療器具。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US39173610P | 2010-10-11 | 2010-10-11 | |
US61/391,736 | 2010-10-11 | ||
PCT/US2011/055566 WO2012051096A1 (en) | 2010-10-11 | 2011-10-10 | Hydrogel jacketed stents |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2013543413A JP2013543413A (ja) | 2013-12-05 |
JP6266980B2 true JP6266980B2 (ja) | 2018-01-24 |
Family
ID=45925747
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2013533908A Active JP6266980B2 (ja) | 2010-10-11 | 2011-10-10 | ヒドロゲルジャケット付きステント |
Country Status (4)
Country | Link |
---|---|
US (2) | US9572653B2 (ja) |
EP (1) | EP2627395B1 (ja) |
JP (1) | JP6266980B2 (ja) |
WO (1) | WO2012051096A1 (ja) |
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CA3192669A1 (en) | 2011-12-06 | 2013-06-13 | Aortic Innovations Llc | Device for endovascular aortic repair and method of using the same |
DE102012007640A1 (de) * | 2012-04-18 | 2013-10-24 | Rheinisch-Westfälische Technische Hochschule Aachen | Stent und Stent-Implantationskatheter |
WO2014062448A1 (en) * | 2012-10-19 | 2014-04-24 | Boston Scientific Scimed, Inc. | Anti-thrombus feature for implanted medical devices |
CN110179567A (zh) * | 2013-03-15 | 2019-08-30 | 瓣膜医学有限公司 | 用于密封经皮瓣膜的系统和方法 |
SG11201707686PA (en) * | 2015-03-19 | 2017-10-30 | Univ Nanyang Tech | A stent assembly and method of preparing the stent assembly |
US20170042551A1 (en) | 2015-08-13 | 2017-02-16 | The Brain Protection Company PTY LTD | Implantable damping devices for treating dementia and associated systems and methods of use |
WO2018005969A1 (en) | 2016-06-30 | 2018-01-04 | Washington University | Device and method of inhibiting endoleaks |
US10653541B2 (en) * | 2016-12-21 | 2020-05-19 | Cook Medical Technologies Llc | Stent delivery assembly |
KR20220011784A (ko) | 2017-07-17 | 2022-01-28 | 안테리스 테크놀로지스 코퍼레이션 | 카테터용 멸균 포장 시스템 |
WO2019142077A1 (en) * | 2018-01-16 | 2019-07-25 | Gyrus Acmi, Inc. | Urological stent |
CN108498208B (zh) * | 2018-04-02 | 2021-07-09 | 中国人民解放军第四军医大学 | 适用于动脉血管的血管支架 |
US10869750B2 (en) * | 2018-09-10 | 2020-12-22 | Rheinisch-Westfälische Technische Hochschule (Rwth) Aachen | Endovascular stent grafts and methods of using said stent grafts |
JP7404547B2 (ja) | 2020-01-20 | 2023-12-25 | アンジオメト・ゲーエムベーハー・ウント・コンパニー・メディツィンテクニク・カーゲー | ステントグラフトおよびキット |
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-
2011
- 2011-10-10 JP JP2013533908A patent/JP6266980B2/ja active Active
- 2011-10-10 EP EP11833191.7A patent/EP2627395B1/en active Active
- 2011-10-10 US US13/269,863 patent/US9572653B2/en active Active
- 2011-10-10 WO PCT/US2011/055566 patent/WO2012051096A1/en active Application Filing
-
2017
- 2017-01-25 US US15/415,783 patent/US20170128191A1/en not_active Abandoned
Also Published As
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EP2627395A1 (en) | 2013-08-21 |
JP2013543413A (ja) | 2013-12-05 |
US20170128191A1 (en) | 2017-05-11 |
WO2012051096A1 (en) | 2012-04-19 |
US20120089218A1 (en) | 2012-04-12 |
EP2627395A4 (en) | 2015-03-11 |
EP2627395B1 (en) | 2017-12-06 |
US9572653B2 (en) | 2017-02-21 |
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