JP6258943B2 - Ｈｍｂおよびａｔｐの組成物ならびに使用方法 - Google Patents
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- 239000000411 inducer Substances 0.000 description 1
- 230000028709 inflammatory response Effects 0.000 description 1
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- 238000001361 intraarterial administration Methods 0.000 description 1
- 230000003834 intracellular effect Effects 0.000 description 1
- 230000009191 jumping Effects 0.000 description 1
- 210000002414 leg Anatomy 0.000 description 1
- 150000002614 leucines Chemical class 0.000 description 1
- 108010022197 lipoprotein cholesterol Proteins 0.000 description 1
- 230000033001 locomotion Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 159000000003 magnesium salts Chemical class 0.000 description 1
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- 238000004949 mass spectrometry Methods 0.000 description 1
- 230000001404 mediated effect Effects 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- QCAWEPFNJXQPAN-UHFFFAOYSA-N methoxyfenozide Chemical compound COC1=CC=CC(C(=O)NN(C(=O)C=2C=C(C)C=C(C)C=2)C(C)(C)C)=C1C QCAWEPFNJXQPAN-UHFFFAOYSA-N 0.000 description 1
- 150000004702 methyl esters Chemical class 0.000 description 1
- 230000004089 microcirculation Effects 0.000 description 1
- 230000003278 mimic effect Effects 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
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- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000009456 molecular mechanism Effects 0.000 description 1
- 125000000896 monocarboxylic acid group Chemical group 0.000 description 1
- 230000004118 muscle contraction Effects 0.000 description 1
- 210000004165 myocardium Anatomy 0.000 description 1
- 230000023837 negative regulation of proteolysis Effects 0.000 description 1
- 210000000885 nephron Anatomy 0.000 description 1
- 239000002858 neurotransmitter agent Substances 0.000 description 1
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- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
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- 230000035699 permeability Effects 0.000 description 1
- 239000002694 phosphate binding agent Substances 0.000 description 1
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- 230000001766 physiological effect Effects 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
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- 230000008092 positive effect Effects 0.000 description 1
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- 230000000559 postactivation potentiation Effects 0.000 description 1
- 159000000001 potassium salts Chemical class 0.000 description 1
- 230000003389 potentiating effect Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 108010043671 prostatic acid phosphatase Proteins 0.000 description 1
- 230000022558 protein metabolic process Effects 0.000 description 1
- 230000004844 protein turnover Effects 0.000 description 1
- 239000003227 purinergic agonist Substances 0.000 description 1
- 150000003212 purines Chemical class 0.000 description 1
- 238000013102 re-test Methods 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 230000020341 sensory perception of pain Effects 0.000 description 1
- SUKJFIGYRHOWBL-UHFFFAOYSA-N sodium hypochlorite Chemical compound [Na+].Cl[O-] SUKJFIGYRHOWBL-UHFFFAOYSA-N 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/06—Anabolic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
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| US201261698919P | 2012-09-10 | 2012-09-10 | |
| US61/698,919 | 2012-09-10 | ||
| PCT/US2013/059039 WO2014040067A1 (en) | 2012-09-10 | 2013-09-10 | Composition of hmb and atp and methods of use |
Publications (3)
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| JP2015527408A JP2015527408A (ja) | 2015-09-17 |
| JP2015527408A5 JP2015527408A5 (cg-RX-API-DMAC7.html) | 2016-11-04 |
| JP6258943B2 true JP6258943B2 (ja) | 2018-01-10 |
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| US10888576B2 (en) * | 2018-10-08 | 2021-01-12 | Metabolic Technologies, Inc. | Composition of HMB and ATP and methods of use |
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| US5028440A (en) | 1990-01-30 | 1991-07-02 | Iowa State University Research Foundation, Inc. | Method of raising meat producing animals to increase lean tissue development |
| US4992470A (en) | 1990-02-08 | 1991-02-12 | Iowa State University Research Foundation, Inc. | Method of enhancing immune response of mammals |
| CA2142314C (en) | 1992-09-16 | 1999-06-01 | Steven L. Nissen | Method of reducing blood levels of total cholesterol and low-density lipoprotein cholesterol |
| US5348979A (en) | 1992-12-23 | 1994-09-20 | Iowa State University Research Foundation Inc. | Method of promoting nitrogen retention in humans |
| US6031000A (en) | 1998-06-23 | 2000-02-29 | Iowa State University Research Foundation, Inc. | Composition comprising β-hydroxy-β-methylbutyric acid and at least one amino acid and methods of use |
| JP4010390B2 (ja) * | 1999-09-20 | 2007-11-21 | 明治乳業株式会社 | 免疫賦活化組成物 |
| US7629329B2 (en) * | 2001-06-04 | 2009-12-08 | Tsi Health Sciences, Inc. | Method for increasing muscle mass and strength through administration of adenosine triphosphate |
| US20050027005A1 (en) * | 2003-08-02 | 2005-02-03 | Matthias Boldt | Nutrient compositions and methods for sustenance and promotion of positive metabolic energy levels in a targeted manner |
| US20050215640A1 (en) * | 2004-03-26 | 2005-09-29 | Baxter Jeffrey H | HMB compositions and uses thereof |
| US20060083793A1 (en) * | 2004-09-29 | 2006-04-20 | Gardiner Paul T | Nutritional composition for promoting muscle performance and acting as hydrogen (H+) blocker |
| US20060073891A1 (en) * | 2004-10-01 | 2006-04-06 | Holt Timothy M | Display with multiple user privacy |
| KR101299885B1 (ko) * | 2005-05-27 | 2013-08-23 | 코와 가부시키가이샤 | 피로 회복을 위한 의약 |
| WO2007108071A1 (ja) * | 2006-03-17 | 2007-09-27 | Pharma Foods International Co., Ltd. | 抗ストレス組成物及びそれを含有する飲食品 |
| PL2381784T3 (pl) * | 2008-12-09 | 2019-01-31 | Metabolic Technologies, Inc. | Interwencyjny produkt odżywczy w celu poprawy funkcji i siły mięśni |
| DE102009052640A1 (de) | 2009-11-10 | 2011-05-12 | Linde-Lkca-Dresden Gmbh | Verfahren und Vorrichtung zur Gaswäsche |
| WO2011075741A1 (en) * | 2009-12-18 | 2011-06-23 | Metabolic Technologies, Inc. | Improved method of administering beta-hydroxy-beta-methylbutyrate (hmb) |
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Also Published As
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| CA2884405A1 (en) | 2014-03-13 |
| EP2892522A1 (en) | 2015-07-15 |
| ES2970283T3 (es) | 2024-05-27 |
| JP2015527408A (ja) | 2015-09-17 |
| EP3733171A1 (en) | 2020-11-04 |
| EP2892522A4 (en) | 2016-01-20 |
| EP3733171B1 (en) | 2023-10-25 |
| AU2013312113B2 (en) | 2018-08-02 |
| BR112015005199A2 (pt) | 2017-07-04 |
| CA2884405C (en) | 2021-03-30 |
| PL3733171T3 (pl) | 2024-03-18 |
| CN105025891B (zh) | 2020-01-21 |
| BR112015005199B1 (pt) | 2022-09-06 |
| DK3733171T3 (da) | 2024-01-29 |
| US10092590B2 (en) | 2018-10-09 |
| FI3733171T3 (fi) | 2024-01-24 |
| AU2013312113A1 (en) | 2015-03-26 |
| US20140080781A1 (en) | 2014-03-20 |
| HUE065064T2 (hu) | 2024-05-28 |
| WO2014040067A1 (en) | 2014-03-13 |
| HK1217087A1 (zh) | 2016-12-23 |
| CN105025891A (zh) | 2015-11-04 |
| PT3733171T (pt) | 2024-01-31 |
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