JP6240658B2 - 抗がん活性を有する６−オキソ−１，６−ジヒドロ−ピリダジン誘導体と他の抗腫瘍化合物との組み合わせ - Google Patents
抗がん活性を有する６−オキソ−１，６−ジヒドロ−ピリダジン誘導体と他の抗腫瘍化合物との組み合わせ Download PDFInfo
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12001847.8 | 2012-03-19 | ||
| EP12001847 | 2012-03-19 | ||
| PCT/EP2013/000495 WO2013139423A1 (en) | 2012-03-19 | 2013-02-21 | Combination of a 6-oxo-1,6-dihydro-pyridazine derivative having anti-cancer activity with other anti-tumor compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015514064A JP2015514064A (ja) | 2015-05-18 |
| JP6240658B2 true JP6240658B2 (ja) | 2017-11-29 |
Family
ID=47749755
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015500785A Active JP6240658B2 (ja) | 2012-03-19 | 2013-02-21 | 抗がん活性を有する６−オキソ−１，６−ジヒドロ−ピリダジン誘導体と他の抗腫瘍化合物との組み合わせ |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20150044211A1 (es) |
| EP (1) | EP2827872A1 (es) |
| JP (1) | JP6240658B2 (es) |
| KR (1) | KR20140138984A (es) |
| CN (1) | CN104203243A (es) |
| AU (1) | AU2013234767B2 (es) |
| BR (1) | BR112014022266A2 (es) |
| CA (1) | CA2867637A1 (es) |
| MX (1) | MX2014010982A (es) |
| RU (1) | RU2014141934A (es) |
| WO (1) | WO2013139423A1 (es) |
| ZA (1) | ZA201407577B (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20160324855A1 (en) * | 2014-01-07 | 2016-11-10 | Merck Patente Gmbh | Combination of a 6-oxo-1,6-dihydro-pyridazine derivative having anti-cancer activity with gefitinib |
| EP3229796B1 (en) * | 2014-12-11 | 2023-03-01 | Merck Patent GmbH | Combination of a 6-oxo-1,6-dihydro-pyridazine derivative having anti-cancer activity with a quinazoline derivative |
| AU2015360005A1 (en) * | 2014-12-12 | 2017-07-27 | Merck Patent Gmbh | Combination of a 6-oxo-1,6-dihydro-pyridazine derivative having anti-cancer activity with an EGFR inhibitor |
| HUE051734T2 (hu) * | 2016-10-27 | 2021-03-29 | Fujian Cosunter Pharmaceutical Co Ltd | Piridon-vegyület, mint C-Met inhibitor |
| BR112022000266A2 (pt) * | 2019-07-10 | 2022-05-17 | Merck Patent Gmbh | Preparação farmacêutica |
| CN112263582B (zh) * | 2020-11-04 | 2022-03-15 | 温州医科大学 | S100A8/A9蛋白抑制剂Tepotinib及其应用 |
| CA3233567A1 (en) * | 2021-10-05 | 2023-04-13 | Jill HALLIN | Combination therapies of kras g12d inhibitors with pan erbb family inhibitors |
| CN116768868B (zh) * | 2023-08-15 | 2023-12-08 | 云南省药物研究所 | 一种哒嗪酮硫代衍生物及其制备方法和应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102007032507A1 (de) * | 2007-07-12 | 2009-04-02 | Merck Patent Gmbh | Pyridazinonderivate |
| EP2373640B1 (en) * | 2009-01-08 | 2014-07-30 | Merck Patent GmbH | Novel polymorphic forms of 3-(1-{3-[5-(1-methyl-piperidin-4ylmethoxy)-pyrimidin-2-yl]-benzyl}-6-oxo-1,6-dihydro-pyridazin-3-yl)-benzonitrile hydrochloride salt and processes of manufacturing thereof |
-
2013
- 2013-02-21 JP JP2015500785A patent/JP6240658B2/ja active Active
- 2013-02-21 WO PCT/EP2013/000495 patent/WO2013139423A1/en active Application Filing
- 2013-02-21 MX MX2014010982A patent/MX2014010982A/es unknown
- 2013-02-21 CN CN201380015339.2A patent/CN104203243A/zh active Pending
- 2013-02-21 US US14/386,164 patent/US20150044211A1/en not_active Abandoned
- 2013-02-21 RU RU2014141934A patent/RU2014141934A/ru not_active Application Discontinuation
- 2013-02-21 EP EP13705919.2A patent/EP2827872A1/en not_active Withdrawn
- 2013-02-21 AU AU2013234767A patent/AU2013234767B2/en active Active
- 2013-02-21 CA CA2867637A patent/CA2867637A1/en not_active Abandoned
- 2013-02-21 BR BR112014022266-5A patent/BR112014022266A2/pt not_active Application Discontinuation
- 2013-02-21 KR KR20147029130A patent/KR20140138984A/ko not_active Application Discontinuation
-
2014
- 2014-10-17 ZA ZA2014/07577A patent/ZA201407577B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA201407577B (en) | 2016-02-24 |
| US20150044211A1 (en) | 2015-02-12 |
| BR112014022266A2 (pt) | 2021-09-08 |
| EP2827872A1 (en) | 2015-01-28 |
| AU2013234767A1 (en) | 2014-10-30 |
| RU2014141934A (ru) | 2016-05-20 |
| CN104203243A (zh) | 2014-12-10 |
| WO2013139423A1 (en) | 2013-09-26 |
| CA2867637A1 (en) | 2013-09-26 |
| AU2013234767B2 (en) | 2017-02-23 |
| KR20140138984A (ko) | 2014-12-04 |
| MX2014010982A (es) | 2014-10-13 |
| JP2015514064A (ja) | 2015-05-18 |
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