JP6239118B2 - 医薬化合物 - Google Patents
医薬化合物 Download PDFInfo
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- JP6239118B2 JP6239118B2 JP2016537144A JP2016537144A JP6239118B2 JP 6239118 B2 JP6239118 B2 JP 6239118B2 JP 2016537144 A JP2016537144 A JP 2016537144A JP 2016537144 A JP2016537144 A JP 2016537144A JP 6239118 B2 JP6239118 B2 JP 6239118B2
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- disease
- compound
- tyk2
- alkyl
- oxazole
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Classifications
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| WO2019132654A1 (en) * | 2017-12-27 | 2019-07-04 | Erasmus University Medical Center Rotterdam | Methods of treating sarcoidosis |
| WO2020009566A1 (en) * | 2018-07-04 | 2020-01-09 | Erasmus University Medical Center Rotterdam | Methods of treating sarcoidosis |
| GB201816369D0 (en) | 2018-10-08 | 2018-11-28 | Sareum Ltd | Pharmaceutical compounds |
| CN114269336A (zh) | 2019-04-30 | 2022-04-01 | 细胞基因公司 | 包含阿普斯特和tyk2抑制剂的联合疗法 |
| GB202005114D0 (en) | 2020-04-07 | 2020-05-20 | Sareum Ltd | Crystalline Forms of a Pharmaceutical Compound |
| EP3944859A1 (en) | 2020-07-30 | 2022-02-02 | Assistance Publique Hôpitaux de Paris | Method for treating immune toxicities induced by immune checkpoint inhibitors |
| JP2024535467A (ja) | 2021-09-30 | 2024-09-30 | ブリストル－マイヤーズ スクイブ カンパニー | Ｔｙｋ２阻害剤に対する応答性を決定する方法 |
| JP2024539280A (ja) | 2021-10-25 | 2024-10-28 | カイメラ セラピューティクス， インコーポレイテッド | Ｔｙｋ２分解剤およびそれらの使用 |
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| GB1497536A (en) * | 1973-12-17 | 1978-01-12 | Lilly Industries Ltd | 2-acylaminooxazoles methods for their preparation and their use |
| CA2329065A1 (en) * | 1998-05-05 | 1999-11-11 | Francisco Xavier Talamas | Pyrazole derivatives as p-38 map kinase inhibitors |
| GB0709031D0 (en) * | 2007-05-10 | 2007-06-20 | Sareum Ltd | Pharmaceutical compounds |
| ES2395581T3 (es) | 2007-06-20 | 2013-02-13 | Merck Sharp & Dohme Corp. | Inhibidores de quinasas janus |
| US8278335B2 (en) | 2008-04-21 | 2012-10-02 | Merck Sharp & Dohme Corp. | Inhibitors of Janus kinases |
| US8344144B2 (en) | 2008-06-18 | 2013-01-01 | Merck Sharp & Dohme Corp. | Inhibitors of Janus kinases |
| EP2310384B1 (en) | 2008-07-09 | 2014-04-09 | Merck Sharp & Dohme Corp. | Inhibitors of janus kinases |
| EP2166006A1 (en) * | 2008-09-18 | 2010-03-24 | Dompe' S.P.A. | 2-aryl-propionic acids and derivatives and pharmaceutical compositions containing them |
| GB0820819D0 (en) * | 2008-11-13 | 2008-12-24 | Sareum Ltd | Pharmaceutical compounds |
| CN102869359A (zh) | 2010-03-17 | 2013-01-09 | 弗·哈夫曼-拉罗切有限公司 | 咪唑并吡啶和嘌呤化合物、组合物和使用方法 |
| US20130143915A1 (en) | 2010-07-01 | 2013-06-06 | Cellzome Limited | Triazolopyridines as tyk2 inhibitors |
| PH12014500730A1 (en) | 2011-10-12 | 2018-01-17 | Array Biopharma Inc | 5,7-substituted-imidazo[1,2-c]pyrimidines |
| EP3040336B1 (en) * | 2012-03-02 | 2020-04-08 | Sareum Limited | Compounds for use in treating tyk2 kinase mediated conditions |
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| BR112016004723B1 (pt) | 2022-08-30 |
| AU2013399913B2 (en) | 2018-03-15 |
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| MX369974B (es) | 2019-11-27 |
| AU2013399913A1 (en) | 2016-03-24 |
| CN105793245B (zh) | 2018-03-20 |
| ZA201602047B (en) | 2020-12-23 |
| CN105793245A (zh) | 2016-07-20 |
| KR102191084B1 (ko) | 2020-12-15 |
| SG11201601503SA (en) | 2016-03-30 |
| KR20160048883A (ko) | 2016-05-04 |
| RU2016111522A (ru) | 2017-10-09 |
| MX2016002738A (es) | 2016-08-11 |
| IL244380B (en) | 2018-01-31 |
| RU2652795C2 (ru) | 2018-05-03 |
| CA2941824C (en) | 2020-08-25 |
| IL244380A0 (en) | 2016-04-21 |
| WO2015032423A1 (en) | 2015-03-12 |
| CA2941824A1 (en) | 2015-03-12 |
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