JP6228659B2 - 押しボタン式安全インジェクタ - Google Patents

押しボタン式安全インジェクタ Download PDF

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Publication number
JP6228659B2
JP6228659B2 JP2016501367A JP2016501367A JP6228659B2 JP 6228659 B2 JP6228659 B2 JP 6228659B2 JP 2016501367 A JP2016501367 A JP 2016501367A JP 2016501367 A JP2016501367 A JP 2016501367A JP 6228659 B2 JP6228659 B2 JP 6228659B2
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Japan
Prior art keywords
safety
push button
safety injector
injector
injection
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JP2016501367A
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English (en)
Japanese (ja)
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JP2016515020A (ja
Inventor
スワンソン，ケヴィン・デヴィッド
サンド，ジュリアス
ヘフト，ピーター・エイ
マドセン，パトリック，イー
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アンタレス・ファーマ・インコーポレーテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2026—Semi-automatic, e.g. user activated piston is assisted by additional source of energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/206—With automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2073—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically preventing premature release, e.g. by making use of a safety lock
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2073—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically preventing premature release, e.g. by making use of a safety lock
    • A61M2005/208—Release is possible only when device is pushed against the skin, e.g. using a trigger which is blocked or inactive when the device is not pushed against the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321—Means for protection against accidental injuries by used needles
    • A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
    • A61M5/3245—Constructional features thereof, e.g. to improve manipulation or functioning
    • A61M2005/3247—Means to impede repositioning of protection sleeve from needle covering to needle uncovering position
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321—Means for protection against accidental injuries by used needles
    • A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
    • A61M5/326—Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
    • A61M2005/3267—Biased sleeves where the needle is uncovered by insertion of the needle into a patient's body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/30—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3202—Devices for protection of the needle before use, e.g. caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3202—Devices for protection of the needle before use, e.g. caps
    • A61M5/3204—Needle cap remover, i.e. devices to dislodge protection cover from needle or needle hub, e.g. deshielding devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321—Means for protection against accidental injuries by used needles
    • A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
    • A61M5/326—Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
JP2016501367A 2013-03-13 2014-03-12 押しボタン式安全インジェクタ Active JP6228659B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361779559P 2013-03-13 2013-03-13
US61/779,559 2013-03-13
PCT/US2014/023862 WO2014164943A1 (en) 2013-03-13 2014-03-12 Push button safety injector

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2017196690A Division JP2018020195A (ja) 2013-03-13 2017-10-10 押しボタン式安全インジェクタ

Publications (2)

Publication Number Publication Date
JP2016515020A JP2016515020A (ja) 2016-05-26
JP6228659B2 true JP6228659B2 (ja) 2017-11-08

Family

ID=51659016

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2016501367A Active JP6228659B2 (ja) 2013-03-13 2014-03-12 押しボタン式安全インジェクタ
JP2017196690A Pending JP2018020195A (ja) 2013-03-13 2017-10-10 押しボタン式安全インジェクタ
JP2019098373A Active JP6876093B2 (ja) 2013-03-13 2019-05-27 押しボタン式安全インジェクタ

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2017196690A Pending JP2018020195A (ja) 2013-03-13 2017-10-10 押しボタン式安全インジェクタ
JP2019098373A Active JP6876093B2 (ja) 2013-03-13 2019-05-27 押しボタン式安全インジェクタ

Country Status (6)

Country Link
US (2) US10124115B2 (enExample)
EP (1) EP2968773B1 (enExample)
JP (3) JP6228659B2 (enExample)
CA (1) CA2903484C (enExample)
ES (1) ES2795977T3 (enExample)
WO (1) WO2014164943A1 (enExample)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6228659B2 (ja) * 2013-03-13 2017-11-08 アンタレス・ファーマ・インコーポレーテッド 押しボタン式安全インジェクタ
WO2015074984A1 (en) * 2013-11-22 2015-05-28 Sanofi-Aventis Deutschland Gmbh Drug delivery device with dose knob clutch
WO2015122964A1 (en) 2014-02-11 2015-08-20 Dexcom, Inc. Packaging system for analyte sensors
TW201709940A (zh) 2015-06-03 2017-03-16 賽諾菲阿凡提斯德意志有限公司 聲響指示器（一）
TW201709941A (zh) 2015-06-03 2017-03-16 賽諾菲阿凡提斯德意志有限公司 聲響指示器（二）
TW201711713A (zh) 2015-06-03 2017-04-01 賽諾菲阿凡提斯德意志有限公司 藥物輸送裝置（五）
TW201700118A (zh) 2015-06-03 2017-01-01 賽諾菲阿凡提斯德意志有限公司 藥物輸送裝置（三）
TW201707737A (zh) 2015-06-03 2017-03-01 賽諾菲阿凡提斯德意志有限公司 藥物輸送裝置（一）
US10810908B2 (en) * 2015-08-11 2020-10-20 Noble International, Inc. Prefilled syringe training device with releaseably locking needle guard
CN108367125B (zh) 2015-12-08 2022-01-25 贝克顿迪金森法国公司 用于医用注射器的帽
GB2606087B (en) 2016-06-06 2023-03-08 E3D Agricultural Cooporative Association Ltd Multiple use computerized injector
EP3474928A4 (en) * 2016-06-22 2020-02-26 Antares Pharma, Inc. NADELSCHUTZENTFERNER
EP3323448A1 (en) * 2016-11-18 2018-05-23 Carebay Europe Ltd. Medicament delivery device
ES2951416T3 (es) 2017-06-08 2023-10-20 Becton Dickinson Co Dispositivo de separación de fluidos biológicos
EP4154802B1 (en) * 2017-06-19 2024-02-14 Dexcom, Inc. Applicators for applying transcutaneous analyte sensors
DK3703783T3 (da) 2017-11-03 2025-03-31 Sanofi Sa Medicinafgivelsesanordning
EP3703784B1 (en) 2017-11-03 2025-09-03 Sanofi Drug delivery device
CA3099359A1 (en) 2018-05-24 2019-11-28 Novartis Ag Automatic drug delivery device
JP7194756B2 (ja) 2018-06-08 2022-12-22 アンタレス・ファーマ・インコーポレーテッド 自動挿入注射器
USD888252S1 (en) 2018-06-18 2020-06-23 Dexcom, Inc. Transcutaneous analyte sensor applicator
CA3204309A1 (en) 2018-07-24 2020-02-20 Antares Pharma, Inc. Injector with safety cap
USD946141S1 (en) 2018-09-20 2022-03-15 Janssen Pharmaceuticals, Inc. Autoinjector
CA3127415A1 (en) * 2019-02-26 2020-09-03 Becton Dickinson France Rigid needle shield remover for autoinjector
WO2020200995A1 (en) * 2019-03-29 2020-10-08 Sanofi Drug delivery device and method for assembling
WO2021019443A1 (en) * 2019-07-31 2021-02-04 Janssen Pharmaceuticals, Inc. Injection device with ergonomic housing form factor
CA3209084A1 (en) * 2021-03-10 2022-09-15 Amgen Inc. Drug delivery device
EP4448051A1 (en) * 2021-12-14 2024-10-23 SHL Medical AG A sub-assembly of a medicament delivery device

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9100819D0 (en) * 1991-01-15 1991-02-27 Medimech Int Ltd Subcutaneous injector
US6428528B2 (en) * 1998-08-11 2002-08-06 Antares Pharma, Inc. Needle assisted jet injector
US7018365B2 (en) * 1999-05-21 2006-03-28 Micro Therapeutics, Inc. Threaded syringe with quick stop
US7698157B2 (en) 2002-06-12 2010-04-13 Anvita, Inc. System and method for multi-dimensional physician-specific data mining for pharmaceutical sales and marketing
WO2004041331A1 (en) * 2002-11-01 2004-05-21 Antares Pharma, Inc. Administration of insulin by jet injection
DE10315200B4 (de) 2003-04-03 2005-03-17 3+Extruder Gmbh Getriebe zum Antrieb eines Mehrwellenextruders
DE10351599A1 (de) 2003-11-05 2005-06-16 Tecpharma Licensing Ag Autoinjektionsvorrichtung
US20050101919A1 (en) 2003-11-07 2005-05-12 Lennart Brunnberg Device for an injector
AU2004298302B2 (en) * 2003-12-18 2009-04-02 Tecpharma Licensing Ag Releasable injection device
FR2899482A1 (fr) * 2006-04-11 2007-10-12 Becton Dickinson France Soc Pa Dispositif d'injection automatique
KR101448634B1 (ko) 2007-11-07 2014-10-08 엘지전자 주식회사 복호화 실패 또는 신뢰도에 따라 패킷을 재전송하는 방법
WO2009063030A1 (en) 2007-11-14 2009-05-22 Shl Group Ab Automatic injection device with actively triggered syringe withdrawal
GB0724944D0 (en) * 2007-12-20 2008-01-30 Ucb Pharma Sa Auto injector
US8814834B2 (en) * 2008-03-10 2014-08-26 Antares Pharma, Inc. Injector safety device
JP4361962B1 (ja) 2009-01-30 2009-11-11 株式会社アルテ 容器兼用注射器
GB0910681D0 (en) * 2009-06-19 2009-08-05 Ucb Pharma Sa Auto-injector
EP2364741A1 (en) * 2010-03-09 2011-09-14 Sanofi-Aventis Deutschland GmbH Interlock mechanism for defining an operation sequence of an auto-injector
GB201020472D0 (en) * 2010-12-02 2011-01-19 Oval Medical Technologies Ltd A drive assembly for an autoinjector
US8496619B2 (en) * 2011-07-15 2013-07-30 Antares Pharma, Inc. Injection device with cammed ram assembly
JP6228659B2 (ja) * 2013-03-13 2017-11-08 アンタレス・ファーマ・インコーポレーテッド 押しボタン式安全インジェクタ

Also Published As

Publication number Publication date
JP2018020195A (ja) 2018-02-08
CA2903484C (en) 2019-01-08
JP2019150659A (ja) 2019-09-12
JP2016515020A (ja) 2016-05-26
ES2795977T3 (es) 2020-11-25
US20160015897A1 (en) 2016-01-21
CA2903484A1 (en) 2014-10-09
EP2968773B1 (en) 2020-05-06
EP2968773A4 (en) 2016-11-09
WO2014164943A1 (en) 2014-10-09
US10835676B2 (en) 2020-11-17
US10124115B2 (en) 2018-11-13
US20190046728A1 (en) 2019-02-14
JP6876093B2 (ja) 2021-05-26
EP2968773A1 (en) 2016-01-20

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