JP6218152B2 - 内耳細胞誘導方法 - Google Patents
内耳細胞誘導方法 Download PDFInfo
- Publication number
- JP6218152B2 JP6218152B2 JP2015098423A JP2015098423A JP6218152B2 JP 6218152 B2 JP6218152 B2 JP 6218152B2 JP 2015098423 A JP2015098423 A JP 2015098423A JP 2015098423 A JP2015098423 A JP 2015098423A JP 6218152 B2 JP6218152 B2 JP 6218152B2
- Authority
- JP
- Japan
- Prior art keywords
- cells
- inner ear
- culturing
- stem cells
- bfgf
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2015098423A JP6218152B2 (ja) | 2014-05-13 | 2015-05-13 | 内耳細胞誘導方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2014100017 | 2014-05-13 | ||
| JP2014100017 | 2014-05-13 | ||
| JP2015098423A JP6218152B2 (ja) | 2014-05-13 | 2015-05-13 | 内耳細胞誘導方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015231365A JP2015231365A (ja) | 2015-12-24 |
| JP2015231365A5 JP2015231365A5 (enExample) | 2017-06-01 |
| JP6218152B2 true JP6218152B2 (ja) | 2017-10-25 |
Family
ID=54933292
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015098423A Active JP6218152B2 (ja) | 2014-05-13 | 2015-05-13 | 内耳細胞誘導方法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP6218152B2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023033149A1 (ja) | 2021-09-03 | 2023-03-09 | 学校法人北里研究所 | 内耳血管条辺縁細胞の製造方法、薬剤の評価方法、及び薬剤評価用細胞培養物 |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6850025B2 (ja) * | 2016-02-22 | 2021-03-31 | 学校法人順天堂 | 内耳細胞の製造法 |
| JP2023106640A (ja) * | 2020-06-09 | 2023-08-02 | 株式会社オトリンク | 内耳有毛細胞の製造方法、薬剤の評価方法、及び細胞分化誘導用組成物 |
| JP2023106639A (ja) * | 2020-06-09 | 2023-08-02 | 株式会社オトリンク | 内耳前駆細胞の製造方法、内耳有毛細胞の製造方法、薬剤の評価方法、及び内耳細胞分化誘導用組成物 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2464723B1 (en) * | 2009-08-12 | 2016-06-22 | Kyoto University | Method for inducing differentiation of pluripotent stem cells into neural precursor cells |
| US9624468B2 (en) * | 2012-05-04 | 2017-04-18 | Indiana University Research & Technology Corporation | Methods for generating the inner ear and other cranial placode-derived tissues using pluripotent stem cells |
| WO2013187416A1 (ja) * | 2012-06-12 | 2013-12-19 | 学校法人 慶應義塾 | 神経系分化に適したiPS細胞の増幅方法、及び神経幹細胞の誘導方法 |
-
2015
- 2015-05-13 JP JP2015098423A patent/JP6218152B2/ja active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023033149A1 (ja) | 2021-09-03 | 2023-03-09 | 学校法人北里研究所 | 内耳血管条辺縁細胞の製造方法、薬剤の評価方法、及び薬剤評価用細胞培養物 |
| EP4397750A4 (en) * | 2021-09-03 | 2025-08-06 | The Kitasato Inst | METHOD FOR PRODUCING MARGINAL CELLS OF THE VASCULAR STRIA OF THE INNER EAR, METHOD FOR EVALUATING A CHEMICAL AGENT, AND CELL CULTURE FOR EVALUATING A CHEMICAL AGENT |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2015231365A (ja) | 2015-12-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Kwok et al. | Scalable stirred suspension culture for the generation of billions of human induced pluripotent stem cells using single‐use bioreactors | |
| Fonoudi et al. | A universal and robust integrated platform for the scalable production of human cardiomyocytes from pluripotent stem cells | |
| KR101837080B1 (ko) | 마이크로-캐리어 상의 만능 줄기 세포 배양 | |
| Hookway et al. | Aggregate formation and suspension culture of human pluripotent stem cells and differentiated progeny | |
| Lewandowski et al. | Techniques for the induction of human pluripotent stem cell differentiation towards cardiomyocytes | |
| JP2017140052A (ja) | 心筋細胞の生成 | |
| DK2838992T3 (en) | Maintaining differentiated cells with laminins | |
| JP6218152B2 (ja) | 内耳細胞誘導方法 | |
| Kumar et al. | Generation of an expandable intermediate mesoderm restricted progenitor cell line from human pluripotent stem cells | |
| JP2019022509A (ja) | 幹細胞および幹細胞に由来する細胞を単離するための、接着シグネチャーベースの方法 | |
| Sambo et al. | Transient treatment of human pluripotent stem cells with DMSO to promote differentiation | |
| JP7198524B2 (ja) | スフェロイドの製造方法および多能性幹細胞マーカーを発現させる方法 | |
| Liu et al. | Microfibrous carriers for integrated expansion and neural differentiation of embryonic stem cells in suspension bioreactor | |
| Hook et al. | Non-immortalized human neural stem (NS) cells as a scalable platform for cellular assays | |
| CN116731961A (zh) | 一种第三咽囊内胚层的培养方法及应用 | |
| Lee et al. | Clump-passaging-based efficient 3D culture of human pluripotent stem cells under chemically defined conditions | |
| WO2022188395A1 (zh) | 一种多能干细胞的培养方法 | |
| JP2023106639A (ja) | 内耳前駆細胞の製造方法、内耳有毛細胞の製造方法、薬剤の評価方法、及び内耳細胞分化誘導用組成物 | |
| WO2023033149A1 (ja) | 内耳血管条辺縁細胞の製造方法、薬剤の評価方法、及び薬剤評価用細胞培養物 | |
| Okubo et al. | Fabrication of three-dimensional lacrimal gland-like tissue organoids from human pluripotent stem cells | |
| Aluru et al. | Protocol for purifying primitive neural progenitors by fractional passaging to generate astroglia-enriched cerebral organoid | |
| KR20240131080A (ko) | 배외내배엽 줄기세포의 배양용 배지 조성물 | |
| JP2023106640A (ja) | 内耳有毛細胞の製造方法、薬剤の評価方法、及び細胞分化誘導用組成物 | |
| Obrtlíková | Differentiation of Human Embryonic Stem Cells into Endothelial and Smooth Muscle Cells as a Model for Vascular Development | |
| Karamil | Soft tissue stiffness influences early commitment of mouse embryonic stem cells towards endodermal lineage |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20170407 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20170407 |
|
| A871 | Explanation of circumstances concerning accelerated examination |
Free format text: JAPANESE INTERMEDIATE CODE: A871 Effective date: 20170407 |
|
| A975 | Report on accelerated examination |
Free format text: JAPANESE INTERMEDIATE CODE: A971005 Effective date: 20170426 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20170516 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20170707 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20170829 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20170919 |
|
| R150 | Certificate of patent or registration of utility model |
Ref document number: 6218152 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |