JP6198736B2 - 疾患のシグネチャとしてのアイソタイププロファイルの検出 - Google Patents

疾患のシグネチャとしてのアイソタイププロファイルの検出 Download PDF

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JP6198736B2
JP6198736B2 JP2014532073A JP2014532073A JP6198736B2 JP 6198736 B2 JP6198736 B2 JP 6198736B2 JP 2014532073 A JP2014532073 A JP 2014532073A JP 2014532073 A JP2014532073 A JP 2014532073A JP 6198736 B2 JP6198736 B2 JP 6198736B2
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sequencing
isotype
immunoglobulin
disease
cells
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JP2014527831A5 (enExample
JP2014527831A (ja
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マリア ユー. ハッチンズ
マリア ユー. ハッチンズ
ダニエル セリグソン
ダニエル セリグソン
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リネアージュ バイオサイエンシズ, インコーポレイテッド
リネアージュ バイオサイエンシズ, インコーポレイテッド
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2014532073A 2011-09-22 2012-09-24 疾患のシグネチャとしてのアイソタイププロファイルの検出 Active JP6198736B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161537878P 2011-09-22 2011-09-22
US61/537,878 2011-09-22
PCT/US2012/056911 WO2013044234A1 (en) 2011-09-22 2012-09-24 Detection of isotype profiles as signatures for disease

Related Child Applications (1)

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JP2017159019A Division JP2018007689A (ja) 2011-09-22 2017-08-22 疾患のシグネチャとしてのアイソタイププロファイルの検出

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JP2014527831A JP2014527831A (ja) 2014-10-23
JP2014527831A5 JP2014527831A5 (enExample) 2015-11-12
JP6198736B2 true JP6198736B2 (ja) 2017-09-20

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JP2014532073A Active JP6198736B2 (ja) 2011-09-22 2012-09-24 疾患のシグネチャとしてのアイソタイププロファイルの検出
JP2017159019A Pending JP2018007689A (ja) 2011-09-22 2017-08-22 疾患のシグネチャとしてのアイソタイププロファイルの検出

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US (1) US20130078633A1 (enExample)
EP (1) EP2758550B1 (enExample)
JP (2) JP6198736B2 (enExample)
CN (1) CN104271759B (enExample)
AU (1) AU2012312028A1 (enExample)
CA (1) CA2848516C (enExample)
WO (1) WO2013044234A1 (enExample)

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* Cited by examiner, † Cited by third party
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WO2014144495A1 (en) 2013-03-15 2014-09-18 Abvitro, Inc. Single cell bar-coding for antibody discovery
WO2014144822A2 (en) 2013-03-15 2014-09-18 Immumetrix, Inc. Methods and compositions for tagging and analyzing samples
US11203783B2 (en) 2013-11-21 2021-12-21 Repertoire Genesis Incorporation T cell receptor and B cell receptor repertoire analysis system, and use of same in treatment and diagnosis
WO2015138803A1 (en) * 2014-03-12 2015-09-17 Icahn School Of Medicine At Mount Sinai Method for identifying kidney allograft recipients at risk for chronic injury
AU2015279542B2 (en) 2014-06-26 2021-07-29 Icahn School Of Medicine At Mount Sinai Method for diagnosing subclinical and clinical acute rejection by analysis of predictive gene sets
WO2016044227A1 (en) 2014-09-15 2016-03-24 Abvitro, Inc. High-throughput nucleotide library sequencing
CN105040111B (zh) * 2015-05-28 2017-07-14 眭维国 系统性红斑狼疮图谱模型的构建方法
GB201612242D0 (en) * 2016-07-14 2016-08-31 Genome Res Ltd And Cambridge Entpr Ltd Novel kit
CN107179288A (zh) * 2017-07-03 2017-09-19 中国人民解放军第三军医大学 一种唾液中分泌型免疫球蛋白的检测方法
JP7464279B2 (ja) 2018-04-16 2024-04-09 アイカーン スクール オブ メディスン アット マウント シナイ レシピエント血液における移植前トランスクリプトームシグネチャーを使用した急性拒絶反応および腎臓同種異系移植喪失の予測のための方法およびキット
CN110400600A (zh) * 2019-08-01 2019-11-01 枣庄学院 一种基于旋转森林算法的miRNA-疾病相关性预测方法
CN115335535A (zh) * 2020-01-22 2022-11-11 生命科技公司 自身免疫疾病和免疫缺陷病症中的免疫组库生物标志物
CN112485304B (zh) * 2020-12-14 2022-08-09 河北工业大学 一种基于电导法的牛奶检测方法及系统

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5018067A (en) 1987-01-12 1991-05-21 Iameter Incorporated Apparatus and method for improved estimation of health resource consumption through use of diagnostic and/or procedure grouping and severity of illness indicators
US20020038227A1 (en) 2000-02-25 2002-03-28 Fey Christopher T. Method for centralized health data management
US7468032B2 (en) 2002-12-18 2008-12-23 Cardiac Pacemakers, Inc. Advanced patient management for identifying, displaying and assisting with correlating health-related data
US20040122296A1 (en) 2002-12-18 2004-06-24 John Hatlestad Advanced patient management for triaging health-related data
CA2544708A1 (en) * 2003-11-03 2005-05-12 Genenews, Inc. Liver cancer biomarkers
US8262900B2 (en) 2006-12-14 2012-09-11 Life Technologies Corporation Methods and apparatus for measuring analytes using large scale FET arrays
EP2719774B8 (en) * 2008-11-07 2020-04-22 Adaptive Biotechnologies Corporation Methods of monitoring conditions by sequence analysis
WO2011031786A2 (en) * 2009-09-08 2011-03-17 Laboratory Corporation Of America Holdings Compositions and methods for diagnosing autism spectrum disorders

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Publication number Publication date
CN104271759B (zh) 2018-01-16
EP2758550B1 (en) 2016-10-26
AU2012312028A8 (en) 2014-04-24
CA2848516A1 (en) 2013-03-28
JP2018007689A (ja) 2018-01-18
AU2012312028A1 (en) 2014-04-10
EP2758550A1 (en) 2014-07-30
WO2013044234A1 (en) 2013-03-28
US20130078633A1 (en) 2013-03-28
JP2014527831A (ja) 2014-10-23
CA2848516C (en) 2021-06-15
CN104271759A (zh) 2015-01-07

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