JP6189945B2 - 癌および自己免疫疾患の治療に有用な可逆性共有結合ピロロ−またはピラゾロピリミジン - Google Patents

癌および自己免疫疾患の治療に有用な可逆性共有結合ピロロ−またはピラゾロピリミジン Download PDF

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JP6189945B2
JP6189945B2 JP2015517370A JP2015517370A JP6189945B2 JP 6189945 B2 JP6189945 B2 JP 6189945B2 JP 2015517370 A JP2015517370 A JP 2015517370A JP 2015517370 A JP2015517370 A JP 2015517370A JP 6189945 B2 JP6189945 B2 JP 6189945B2
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amino
pyrimidin
carbonyl
pyrazolo
methyl
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JP2015519401A (ja
JP2015519401A5 (https=
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マイケル ゴールドスタイン，デイビッド
マイケル ゴールドスタイン，デイビッド
バーナー，ブレット
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プリンシピア バイオファーマ インコーポレイテッド
プリンシピア バイオファーマ インコーポレイテッド
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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JP2015517370A 2012-06-18 2013-06-11 癌および自己免疫疾患の治療に有用な可逆性共有結合ピロロ−またはピラゾロピリミジン Active JP6189945B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261661203P 2012-06-18 2012-06-18
US61/661,203 2012-06-18
PCT/US2013/045266 WO2013191965A1 (en) 2012-06-18 2013-06-11 Reversible covalent pyrrolo- or pyrazolopyrimidines useful for the treatment cancer and autoimmune diseases

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JP2015519401A JP2015519401A (ja) 2015-07-09
JP2015519401A5 JP2015519401A5 (https=) 2016-08-04
JP6189945B2 true JP6189945B2 (ja) 2017-08-30

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JP2015517370A Active JP6189945B2 (ja) 2012-06-18 2013-06-11 癌および自己免疫疾患の治療に有用な可逆性共有結合ピロロ−またはピラゾロピリミジン

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US (1) US20160045503A1 (https=)
EP (1) EP2861599B1 (https=)
JP (1) JP6189945B2 (https=)
KR (1) KR102150432B1 (https=)
CN (1) CN104487441B (https=)
AU (1) AU2013277582B2 (https=)
CA (1) CA2874461C (https=)
DK (1) DK2861599T3 (https=)
ES (1) ES2776175T3 (https=)
MX (1) MX368112B (https=)
WO (1) WO2013191965A1 (https=)

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