JP6158664B2 - Hair permanent treatment odor pseudo composition - Google Patents

Description

  The present invention can easily and effectively reproduce the essential part of the reaction odor generated when a cold permanent (hereinafter simply referred to as “permanent”) treatment is applied to human hair. The present invention relates to a hair permanent treatment odor pseudo-composition that can be used for evaluation of treatment odor masking or deodorizing effects.

  The general method of hair styling with permanents is performed in two processing steps. In the first step, the cystine-disulfide bridge of hair keratin is cleaved by the action of a composition containing a reducing agent (permanent liquid first agent). Thereafter, the hair is subsequently formed into the desired shape. Next, in the second step, a composition containing a fixing agent, that is, an oxidizing agent (usually hydrogen peroxide) (permanent liquid second agent) is used to regenerate and close the cystine-disulfide bond at a different site from the first. It is done.

  The permanent liquid first agent is a reducing agent such as thioglycolic acid, cysteine or a salt thereof, acetylcysteine or a salt thereof, thiolactic acid or a salt thereof, cysteamine or a salt thereof, thioglycerol, an organic thiol compound such as glycerin ester of thioglycolic acid, and In addition, ammonia or monoethanolamine is blended as an alkaline agent.

  These organic thiol compounds not only cleave disulfide bonds in the hair, but also generate radicals and nucleophilic reactions with sulfur compounds such as cystine in the hair or with the thiol compound itself to produce low molecules such as sulfur compounds. Let These low-molecular-weight compounds have an unpleasant odor called the so-called perm odor, and the unpleasant odor gives a strong stimulus to the practitioner during the treatment, or gives a strong irritation to the practitioner or stays in the room for other customers. It may be uncomfortable. Furthermore, after the treatment, it remains on the hair and cannot be removed even with several shampoos, which is extremely uncomfortable for the subject.

  Conventionally, the unpleasant odor generated by this reaction has been considered to be caused by low molecular sulfur compounds such as hydrogen sulfide, methanethiol, dimethyldisulfide, and dimethyltrisulfide (Patent Document 1).

Deodorization and masking of unpleasant reaction odors with these permanent liquid first agents are regarded as important issues, and various methods have been proposed in the past. For example, a deodorant for cold permanents comprising honey (Patent Document 2), and a deodorant for cold permanents containing at least one of hop, ougon, aloe and butcher bloom hydrophilic organic solvent extracts (Patent Document 3) Deodorant composition for permanent wave, characterized in that it contains at least one natural essential oil obtained from fennel, orange, clove, pine, mint, eucalyptus, mannen wax, roman chamomile (Patent Document 4) ), Dimethol, paracresyl acetate, ethyl tricyclo [5.2.1.0 ^2,6 ] decan-2-ylcarboxylate, tricyclodecenyl acetate, 3,3-dimethylcyclohexyl methyl ketone and phenylethyl A pack containing at least one selected from isoamyl ether Deodorant composition for manent wave (Patent Document 5), coabon, linalool oxide, rosephenone, sandaroa, sandal mysol core, bacdanol, kephalis, cis-p-menthan-7-ol, nerolidol, raspberry ketone, α , 3,3-trimethylcyclohexanemethylfomate, paramethoxyphenethyl alcohol, 2,2,6-trimethylcyclohexanecarboxylic acid ethyl ester and 2,6,6-trimethyl-1-crotonylcyclohexane, tansy oil, basil oil Permanent wave deodorant composition (Patent Document 6), which has a high effect of masking unpleasant odor derived from a mercapto compound containing at least one kind of compound or essential oil, not only during permanent treatment but also after treatment, Permanent C A permanent wave comprising at least one deodorant selected from hiba oil and cypress oil in at least one drug selected from the treatment agent for ave, the first agent and the second agent. An agent (Patent Document 7) has been proposed.

  As described above, the permanent odor-causing substances are conventionally thought to be caused by low-molecular sulfur compounds such as hydrogen sulfide, methyl mercaptan, dimethyl disulfide, and dimethyl trisulfide. Also in the masking or deodorization, a method of selecting a fragrance by using the deodorizing effect on these compounds as an index has been performed. However, even when the fragrance compositions obtained by these methods are used, when the actual permanent treatment is still performed on humans, sufficient deodorization or masking has not yet been achieved. It was.

JP 2002-241237 A JP-A-48-68749 Japanese Patent Laid-Open No. 4-247013 JP-A-8-277210 JP 2000-344636 A JP 2003-277239 A JP 2006-16333 A

  The purpose of the present invention is to carry out a large-scale experimental operation in which a permanent liquid first agent is actually acted on human hair or kamoji, and the odor generated at that time is confirmed by the odor masking agent. Even if it is not performed, it is possible to perform masking of the permanent treatment odor that cannot be removed or to evaluate the deodorizing effect accurately and simply when performing the treatment with the first permanent liquid agent, and the hair permanent treatment odor pseudo composition. It is an object of the present invention to provide a product and a method for evaluating a permanent odor masking or deodorizing effect using the product.

  The present inventors have used a fragrance having a high deodorizing effect on low molecular sulfur compounds such as hydrogen sulfide, methyl mercaptan, dimethyl disulfide, and dimethyl trisulfide, which has been conventionally considered as a causative substance of a permanent treatment odor. However, the effect of deodorization and masking when actually applying permanents to humans is not sufficient, so it is thought that there may be substances different from the causative odor substances that have been considered in the past. We studied earnestly about the odor component generated when one agent is applied to hair. As a result, they found dimethyl diselenide and methyl methyl thioselenide, and discovered that they play an extremely important role as a causative agent of permanent odor. Dimethyl diselenide and methyl methyl thioselenide have been reported as volatile components of garlic, onion and roast coffee (Cai et al. Agric. Food Chem. 1994, 42, 2081-2084., Shah et al. Anal.Chem.2007, 79, 844-853., Meija et al. J. Agric.Food Chem.2003, 51, 5116-5122.) There is no report as a hair permanent odor or fragrance component of hair, and a hair permanent. From the odor and hair, the present inventors have found for the first time.

  Dimethyl diselenide and methyl methyl thioselenide are collagen and gelatin-like compounds having a specific odor, and can reproduce the characteristics of the specific odor in permanent treatment even at low concentrations. The present inventors can effectively select a deodorant fragrance compound for a permanent treatment odor by evaluating the fragrance compound using these dimethyl diselenide and / or methylmethylthioselenide as an index substance for the deodorization effect. And the present invention was completed.

Thus, the present invention provides the following.
(1) A hair permanent treatment odor pseudo composition containing dimethyl diselenide and / or methyl methyl thioselenide.
(2) A hair permanent treatment odor pseudo composition containing 0.1 ppb to 1 ppm of dimethyl diselenide and / or methyl methyl thioselenide.
(3) Method for evaluating reaction odor masking or deodorizing effect generated when cold permanent treatment is applied to human hair using the hair permanent treatment odor pseudo composition according to (1) or (2) .
(4) Masking of reaction odor generated when cold permanent treatment is applied to human hair using the hair permanent treatment odor pseudo composition according to (1) or (2) or evaluation of a fragrance for deodorization Method.
(5) A method for selecting a fragrance for deodorizing or masking a reaction odor generated when a cold permanent treatment is applied to human hair using the method described in (4).
(6) Reaction generated when cold permanent treatment is applied to human hair, characterized in that the fragrance obtained by the method according to (5) is contained in an amount of 30% by mass or more based on the whole fragrance component. A fragrance composition for deodorizing or masking odors.

  Masking or deodorization of reaction odor generated when performing permanent treatment with high accuracy and simplicity by using the hair permanent treatment odor pseudo composition containing dimethyl diselenide and / or methylmethylthioselenide of the present invention The effect can be evaluated, and a fragrance compound for effectively deodorizing or masking a reaction odor generated when a permanent treatment is applied to human hair can be selected. In addition, by preparing a blended fragrance using this selected fragrance compound, it is possible to deodorize or mask the reaction odor generated when a permanent treatment is applied to human hair more effectively than before. It becomes possible to prepare a fragrance composition.

  Embodiments of the present invention will be described below.

  The compound used in the hair permanent treatment odor pseudo composition of the present invention is dimethyl diselenide represented by the following formula (1) and / or methyl methyl thioselenide represented by the following formula (2).

  As mentioned above, dimethyl diselenide and methyl methyl thioselenide have been reported as volatile components of garlic, onion, and roast coffee, but there are no reports of hair permanent odor or hair fragrance component, but hair permanent odor. This is the first time that the present inventors have found from hair and hair.

  In the present invention, the content of dimethyl diselenide or methyl methyl thioselenide in the hair permanent treatment odor pseudo composition in the present invention is preferably 0.1 ppb to 1 ppm, more preferably 1 ppb to 100 ppb, based on mass. If it is less than 0.1 ppb, the odor is weak and may not be recognized as a hair permanent treatment odor, and if it exceeds 1 ppm, the odor is too strong and may not be recognized as a hair permanent treatment odor.

  Both dimethyl diselenide and methyl methyl thioselenide can be used as a hair permanent treatment odor mimic composition, but methyl methyl thioselenide is prone to disproportionation and is somewhat unstable, so it is used in actual evaluation systems. For this, dimethyl diselenide is preferred.

  The hair permanent treatment odor pseudo composition of the present invention contains dimethyl diselenide and / or methyl methyl thioselenide, and these compounds alone can be used sufficiently effectively as a hair permanent treatment odor pseudo composition. Accordingly, sulfur compounds such as hydrogen sulfide, methyl mercaptan, methional, dimethyl sulfide, dimethyl disulfide, and dimethyl trisulfide, which are conventionally known as hair permanent treatment odor substances, may be blended. The compounding amount of these sulfur compounds is not particularly limited, but is 0.01 to 100 parts by mass, preferably 0.1 to 10 parts by mass with respect to 1 part by mass of dimethyl diselenide and / or methyl methyl thioselenide. It can be illustrated.

  The method for obtaining dimethyl diselenide and / or methyl methyl thioselenide used in the present invention is not particularly limited, and commercially available products can be used.

  The method for evaluating the masking or deodorizing of a fragrance for the hair permanent treatment odor pseudo composition in the present invention can be performed as follows, for example. A cup (about 500 mL) with a lid with a straw mouth is prepared, and about 50 μL to 5 mL of a hair permanent treatment odor pseudo composition is dropped into this. Subsequently, about 1/500 to 1/5 of the hair permanent treatment odor pseudo composition is dropped into the cup with the fragrance to be evaluated. Thereafter, the air in the cup is discharged several times to make the inside uniform. After a few minutes, the odor from the straw mouth is evaluated by sensory evaluation to determine whether the odor of the hair permanent treatment odor pseudo composition is masked. The determination can be made on the basis of, for example, 1: not masked at all, 2: not masked so much, 3: almost masked, 4: completely masked. In such an evaluation system, for example, a solution in which about 0.1 ppb to 1 ppm of methyl diselenide or methyl methyl thioselenide is dissolved in ethanol can be used as the hair permanent treatment odor pseudo composition.

  When evaluated by such a method, fragrances having a high masking or deodorizing effect on dimethyl diselenide and / or methyl methyl thioselenide include, for example, p-cymene, β-phenylethyl alcohol, 2-methyl Dodecanal, hexylcinnamic aldehyde, vanillin, amyl methyl ketone, γ-methyl ionone, acetophenone, β-damacenone, 2-methoxynaphthalene, p-cresyl methyl ether, rose oxide, galaxolide, γ-undecalactone, lemon oil, Examples include lavender oil, rose absolute, clove bud oil, cedar wood oil, and patchouli oil, but the fragrance compound or the essential oil selected by the evaluation method is not limited thereto.

  The fragrance compound or essential oil selected by the evaluation method of the present invention is dimethyl diselenide and / or methyl methylthio, which could not be deodorized by the fragrance used as a fragrance for hair permanent odor selected by the conventional evaluation method. It becomes possible to select a fragrance having an effect on selenide, and it can be said that the effect of masking or deodorizing the hair permanent odor is extremely high. Therefore, when preparing a fragrance composition for deodorizing or masking a reaction odor generated when a permanent treatment is applied to human hair, the fragrance compound or essential oil selected by the evaluation method of the present invention is mainly used. By assembling the formulation as described above, it is possible to prepare a blended fragrance composition that has a good fragrance and that has an extremely high deodorizing or masking effect on the reaction odor generated when a permanent treatment is applied to human hair. .

  When preparing a blended fragrance for deodorizing or masking a reaction odor generated when a permanent treatment is applied to human hair, the fragrance compound or essential oil selected by the evaluation method of the present invention Is preferably 30% by mass or more, more preferably 50% by mass or more, and particularly preferably 70% by mass or more. If it is less than 30% by mass, the deodorization or masking effect of the reaction odor generated when the human hair is subjected to the permanent treatment is not so high, and the fragrance compound or essential oil selected completely by the evaluation method of the present invention. If only, the range of the freedom of mixing will be narrowed.

  Examples of the fragrance component other than the fragrance compound or the essential oil selected by the evaluation method of the present invention include α-pinene, cis-3-hexenol, meflosol, norrimbanol (registered trademark of Firmenich), thymol, benzyl acetate, Fruate, raspberry ketone, spirogalvanone (registered trademark of dibodan), fluoropearl, acetic acid, phenylacetic acid, rabienoxime, 2-cyclohexylidene-2-phenylacetonitrile, 2-ethyl-N-methyl-N- (3-methyl Phenyl) -butanamide, 2,3,5-trimethylpyrazine, benzoin and the like, and other hydrocarbons such as menthone, isomenthone, menthol, menthol derivatives, β-pinene, limonene, octanol, p-tert-butyl Cyclohexanol, etc. Aliphatic alcohols, terpene alcohols such as citronellol, geraniol and terpineol, aromatic alcohols such as benzyl alcohol and cinnamic alcohol, aliphatic aldehydes, terpene aldehydes, aromatic aldehydes, acetals, chain ketones, cis-jasmon, Cyclic ketones such as Damascon, Ionone, Methyl Ionone, Terpene Ketones such as Carvone, Mentone, Camphor, Aromatic Ketones such as Propiophenone and p-Methylacetophenone, Ethers such as Dibenzyl Ether, Linalol Oxide, Rose Oxide, etc. Oxides, synthetic musks such as cyclopentadecanolide, lactones such as γ-nonalactone, aliphatic esters such as acetate, propionate and butyrate, benzoate Esters, phenylacetic acid esters, aromatic esters, such as salicylic acid ester, orange oil, lime oil, bergamot oil, lavandin oil, geranium oil, eucalyptus oil, peppermint oil, and the like natural essential oils such as sandalwood oil.

  As the hair cosmetic composition containing the masking or deodorant fragrance composition of the present invention, the permanent liquid first agent or the permanent liquid second agent is preferable, but besides these, a hair straightener, a decoloring agent, a hair dye, Hair cosmetics that contain or generate odor components such as hair bleach and hair remover. The compounding quantity in the hair cosmetics of the masking or deodorant fragrance | flavor composition of this invention is 0.01-2.0 mass% normally.

  In addition to the above ingredients, hair cosmetics include, as a main ingredient for cosmetics, a permanent agent, a hair straightener, a reducing agent when used as a decoloring agent, an oxidation dye when used as a hair dye, a direct dye, Dyes such as acid dyes, oil-soluble dyes and basic dyes can be used.

  Examples of reducing agents for use as permanent agents, hair straighteners, and depigmenting agents include thioglycolic acid, thioglycolate, cysteine, glyceryl thioglycolate, thioglycerin, cysteamine thiosulfate, and sodium pyrosulfite. Can be mentioned.

  In addition to the above-described components, the permanent agent, hair straightener, and depigmenting agent are other components used in normal cosmetics, for example, alcohols such as aromatic alcohols and polyhydric alcohols, cationic surfactants, anions Surfactants, nonionic surfactants, amphoteric surfactants, preservatives, ultraviolet inhibitors, metal sequestering agents, and the like can be appropriately blended within a range that does not impair the effects of the present invention.

  Next, the present invention will be described in more detail with reference to examples and comparative examples. In addition, unless otherwise indicated, the compounding quantity given below is represented by the mass%.

(Example 1) Identification of odor-causing substances for hair permanent treatment After washing the heads of two 20 to 40-year-old Japanese men and two women with unscented shampoo, unscented permanent liquid no. 1 agent (14.0 parts by weight of 50% ammonium thioglycolate, 2.5 parts by weight of 40% diammonium dithioglycolate, 1.0 part by weight of 28% aqueous ammonia, 1.5 parts by weight of ammonium bicarbonate, monoethanolamine 50 parts of a mixture of 1.0 part by weight, 4.0 parts by weight of an amino-modified silicone emulsion, 2.0 parts by weight of glycerin, and 74.0 parts by weight of purified water) is uniformly applied to the hair, and the hair on the head grows. The side where it is located was covered with an odor collection bag made of polyethylene. TenaxTA is placed as the adsorbent as the first stage in the state where air enters through the activated carbon from the hole opened in the back of the head, and the liquid is placed as the second stage at the tip of the hole drilled in the top of the head. A trap cooled with nitrogen (-196 ° C) is installed, and a suction pump is installed at the tip. Air is sucked by the pump at a rate of 200 mL / min, and the odor generated by the permanent liquid first agent treatment is collected. did. TenaxTA adsorbed with odor was analyzed by GC-MS / O after heat desorption, and the odor component in the liquid nitrogen trap was heated and volatilized and analyzed by GC-MS / O.

  As a result of analyzing the analysis data, hydrogen sulfide, methyl mercaptan, methional, dimethyl sulfide, dimethyl disulfide, dimethyl trisulfide, and the like were recognized as odors generated by the first liquid treatment of the permanent liquid. In addition, two characteristic peaks that were considered to be extremely important as odors during permanent treatment were found in the smell sniffing, and these were confirmed to be dimethyl diselenide and methyl methyl thioselenide.

  The sensory evaluation of these compounds is shown in Table 1.

  As shown in Table 1, hydrogen sulfide, methyl mercaptan, methional, dimethyl sulfide, dimethyl disulfide, dimethyl trisulfide and the like were also recognized as important perm odors, but dimethyl diselenide and methyl methyl thioselenide are It was recognized as a particularly important perm odor. Odor characteristics of these compounds were evaluated as collagen-like and gelatin-like, but were evaluated as extremely important off-flavor components as a treatment odor during or after the permanent treatment. Of these two products, methylmethylthioselenide is prone to disproportionation and is somewhat unstable, and thus actual masking evaluation was performed using dimethyl diselenide.

Example 2 Masking Evaluation for Dimethyl Diselenide Plastic Cup with Straw Mouth (Cup: New Promax (Asahi Kasei Pax)) 520 mL Diameter 96 × Height 119 mm, Lid: New Promax (Asahi Kasei Pax) Common Cap Diameter 96 × A filter paper was laid on the bottom of 7 mm in height, and 500 μL of 0.01 ppm dimethyl diselenide solution (diluted in ethanol) was dropped. Then, add 10 μL of the fragrance to be tested, press the side part of the cup to indent or inflate it, put air in and out, homogenize the inside air, let it stand, and after 5 minutes, The sensory evaluation was carried out by confirming the odor. In addition, as a fragrance compound or an essential oil having a dilution in the table, a diluted solution having a concentration in the table with ethanol was used.

  Odor is determined by 10 panelists. The odor of dimethyl diselenide is 1: not masked at all, 2: not masked very much, 3: almost masked, 4: completely masked It was done on the basis that it is.

  Table 2 shows the fragrance compounds or essential oils tested and the average score for odor determination.

  As a result of the sensory evaluation, those having an average score of 2.5 or more were determined to have a masking or deodorizing effect on dimethyl diselenide. Those exceeding this standard are p-cymene, β-phenylethyl alcohol, 2-methyldodecanal, hexylcinnamic aldehyde, vanillin, amylmethylketone, γ-methylionone, acetophenone, β-damacenone, 2-methoxynaphthalene, p-cresyl methyl ether, rose oxide, galaxolide, γ-undecalactone, lemon oil, lavender oil, rose absolute, clove bud oil, cedar wood oil and patchouli oil.

  Among these, β-phenylethyl alcohol, 2-methyldodecanal, vanillin, amylmethylketone, γ-methylionone, acetophenone, β-damacenone, p-cresylmethyl ether having an average score of 3.0 or more , Rose oxide, lemon oil, lavender oil, and clove bad oil are highly effective. Furthermore, 2-methyldodecanal, vanillin, amylmethylketone, acetophenone, β-damasenone, p, which has an average score of 3.5 or more -Especially effective for cresyl methyl ether and lavender oil.

(Example 3) Evaluation of deodorizing effect in permanent treatment Test human hair was treated by the following steps. During the process, the odor at the time of applying the first liquid of the permanent liquid ((4) in the following process) was sensoryly evaluated, and the treated hair was sealed in a 100 mL glass sample bottle with a lid at 40 ° C. The container was stored, stored for 2 weeks, 1 month and 3 months, and the odor of the mouth of the container when the container lid was opened was evaluated by sensory evaluation. Odor determination was performed by three panelists, and A: sufficiently masked, B: masking was slightly insufficient, and C: masking was insufficient. .
(1) Wash hair with unscented shampoo.
(2) Remove moisture adhering to the hair with a dry towel.
(3) Weigh and bundle 1g of hair.
(4) 1 g of the permanent liquid first agent having the formulation shown in Table 3 is mixed well with the hair.
(5) Leave for 10-15 minutes.
(6) Wash away the liquid attached to the hair with hot water and acid rinse.
(7) Apply the permanent liquid second agent shown in Table 4.
(8) Leave for 10-15 minutes.
(9) Rinse the permanent solution adhering to the hair with hot water.
(10) Air dry for 10-15 minutes.
The time required from step (1) to step (10) is approximately 60 minutes to 70 minutes.

  Table 5 shows the fragrance compounds or essential oils tested and the average score for odor determination.

  As shown in Table 5, the perfume compounds or essential oils that were considered to have a masking or deodorizing effect on dimethyl diselenide in Example 2 were found to have a high masking effect even in tests using actual hair. . It was also recognized that the masking effect was high even after the hair was stored.

(Example 4) Evaluation of deodorizing effect on hair permanent treatment odor pseudo composition using blended fragrance A hair permanent treatment odor pseudo composition was prepared according to the formulation shown in Table 6 below.

  In the same manner as in Example 2, a plastic cup with a straw port (cup: New Promax (Asahi Kasei Packs) 520 mL, caliber 96 × height 119 mm, lid: New Promax (Asahi Kasei Pax) common lid, caliber 96 × height 7 mm) A filter paper was laid on the bottom, and 500 μL of a hair permanent treatment odor pseudo composition prepared according to the formulation of Table 6 was dropped. Then, add 10 μL of the fragrance to be tested, press the side part of the cup to indent or inflate it, put air in and out, homogenize the inside air, let it stand, and after 5 minutes, The sensory evaluation was carried out by confirming the odor.

  Odor is determined by 10 panelists. The odor of the hair permanent treatment odor pseudo composition is 1: not masked at all 2: not masked very much 3: almost masked 4: fully The standard was masked. Table 7 also shows the average point of odor determination.

  As shown in Table 7, the fragrance composition (fragrances 1 to 7) containing 30% by mass or more of the fragrance selected by the masking effect evaluation method using dimethyl diselenide based on the entire fragrance component is human. It was evaluation that it had a high deodorizing effect (2.5 points or more) with respect to masking of the reaction odor (hair permanent treatment odor pseudo composition) generated when the hair was subjected to permanent treatment. Among these, in particular, the fragrance composition (fragrances 1, 3, 4) containing 50% by mass or more of the fragrance selected by the masking effect evaluation method using dimethyl diselenide, based on the entire fragrance component, It was evaluation that it had a very high deodorizing effect (3.0 points or more). On the other hand, the fragrance | flavor composition (fragrance | flavor 8-12) whose fragrance | flavor selected by the evaluation method of the masking effect using dimethyl diselenide is less than 30 mass% on the basis of the whole fragrance | flavor component is not so high in a masking effect. It was an evaluation (less than 2.5 points).

  Based on the above results, dimethyl diselenide or methyl methyl thioselenide can be used as a hair permanent treatment odor pseudo-composition, and the masking or deodorizing effect of the reaction odor that occurs when the permanent treatment is applied is highly accurate and simple. It was confirmed that it can be evaluated. In addition, by using these compounds as a hair permanent treatment odor pseudo composition, it is possible to select a fragrance compound for effectively deodorizing or masking the reaction odor generated when a permanent treatment is applied to human hair. Was recognized. Furthermore, it was confirmed that the fragrance composition prepared using the fragrance compound selected by this method effectively deodorizes or masks the reaction odor generated during the permanent treatment.

Claims (6)

A hair permanent treatment odor simulated composition containing dimethyl diselenide and / or methyl methyl thioselenide. A hair permanent treatment odor pseudo composition containing 0.1 ppb to 1 ppm of dimethyl diselenide and / or methyl methyl thioselenide. A method for masking or deodorizing a reaction odor generated when a cold permanent treatment is performed on human hair using the hair permanent treatment odor pseudo composition according to claim 1 or 2. A method for evaluating reactive odor masking or a deodorizing fragrance produced when a cold permanent treatment is applied to human hair using the hair permanent treatment odor pseudo composition according to claim 1 or 2. The method of selecting the fragrance | flavor for deodorizing or masking the reaction odor which generate | occur | produces when the cold permanent process is performed with respect to human hair using the method of Claim 4. The fragrance evaluated as having a deodorizing effect on dimethyl diselenide and / or methylmethylthioselenide by the method according to claim 5 is 30% by mass or more based on the entire fragrance component. A method for producing a fragrance composition for deodorizing or masking a reaction odor generated when a cold permanent treatment is applied to human hair.