JP6149042B2 - Ｈｅｒ３抗体およびその使用 - Google Patents
Ｈｅｒ３抗体およびその使用 Download PDFInfo
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- JP6149042B2 JP6149042B2 JP2014541312A JP2014541312A JP6149042B2 JP 6149042 B2 JP6149042 B2 JP 6149042B2 JP 2014541312 A JP2014541312 A JP 2014541312A JP 2014541312 A JP2014541312 A JP 2014541312A JP 6149042 B2 JP6149042 B2 JP 6149042B2
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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| US201161557672P | 2011-11-09 | 2011-11-09 | |
| US61/557,672 | 2011-11-09 | ||
| PCT/US2012/064381 WO2013071058A1 (en) | 2011-11-09 | 2012-11-09 | Her3 antibodies and uses thereof |
Publications (3)
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| JP2014533278A JP2014533278A (ja) | 2014-12-11 |
| JP2014533278A5 JP2014533278A5 (enExample) | 2015-12-24 |
| JP6149042B2 true JP6149042B2 (ja) | 2017-06-14 |
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| EP (1) | EP2788377B1 (enExample) |
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| WO (1) | WO2013071058A1 (enExample) |
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| EP2707030B1 (en) | 2011-05-09 | 2020-02-19 | Mayo Foundation For Medical Education And Research | Cancer treatments |
| WO2013078191A1 (en) | 2011-11-23 | 2013-05-30 | Medimmune, Llc | Binding molecules specific for her3 and uses thereof |
| ES2758433T3 (es) * | 2011-12-05 | 2020-05-05 | Novartis Ag | Anticuerpos contra el receptor 3 del factor de crecimiento epidérmico (HER3) |
| WO2014055415A1 (en) | 2012-10-01 | 2014-04-10 | Mayo Foundation For Medical Education And Research | Cancer treatments |
| US11305012B2 (en) | 2013-09-24 | 2022-04-19 | Medimmune, Llc | Binding molecules specific for HER3 and uses thereof |
| US10745490B2 (en) | 2014-04-11 | 2020-08-18 | Celldex Therapeutics, Inc. | Anti-ErbB antibodies and methods of use thereof |
| AU2015274408A1 (en) | 2014-06-13 | 2017-01-12 | Mayo Foundation For Medical Education And Research | Treating lymphomas |
| EA201692502A1 (ru) | 2014-06-16 | 2017-09-29 | Мэйо Фаундейшн Фор Медикал Эдьюкейшн Энд Рисерч | Лечение миелом |
| US9446148B2 (en) | 2014-10-06 | 2016-09-20 | Mayo Foundation For Medical Education And Research | Carrier-antibody compositions and methods of making and using the same |
| WO2016059602A2 (en) * | 2014-10-16 | 2016-04-21 | Glaxo Group Limited | Methods of treating cancer and related compositions |
| TW201707725A (zh) | 2015-08-18 | 2017-03-01 | 美國馬友醫藥教育研究基金會 | 載體－抗體組合物及其製造及使用方法 |
| TW201713360A (en) | 2015-10-06 | 2017-04-16 | Mayo Foundation | Methods of treating cancer using compositions of antibodies and carrier proteins |
| WO2017120501A1 (en) | 2016-01-07 | 2017-07-13 | Mayo Foundation For Medical Education And Research | Methods of treating cancer with interferon |
| CA3014531A1 (en) | 2016-02-12 | 2017-08-17 | Mayo Foundation For Medical Education And Research | Hematologic cancer treatments |
| US11878061B2 (en) | 2016-03-21 | 2024-01-23 | Mayo Foundation For Medical Education And Research | Methods for improving the therapeutic index for a chemotherapeutic drug |
| CA3018341A1 (en) | 2016-03-21 | 2017-09-28 | Mayo Foundation For Medical Education And Research | Methods for reducing toxicity of a chemotherapeutic drug |
| US10618969B2 (en) * | 2016-04-06 | 2020-04-14 | Mayo Foundation For Medical Education And Research | Carrier-binding agent compositions and methods of making and using the same |
| CN109843336A (zh) | 2016-09-01 | 2019-06-04 | 梅约医学教育与研究基金会 | 用于靶向t细胞癌症的方法和组合物 |
| KR102462041B1 (ko) | 2016-09-01 | 2022-11-02 | 메이오 파운데이션 포 메디칼 에쥬케이션 앤드 리써치 | 암 치료용 담체－ｐｄ－ｌ１ 결합제 조성물 |
| EP3509635A1 (en) | 2016-09-06 | 2019-07-17 | Vavotar Life Sciences LLC | Methods of treating triple-negative breast cancer using compositions of antibodies and carrier proteins |
| JP7025412B2 (ja) | 2016-09-06 | 2022-02-24 | マヨ ファウンデーション フォー メディカル エデュケーション アンド リサーチ | パクリタキセル－アルブミン－結合剤組成物並びに該組成物の使用及び製造方法 |
| CN109843924A (zh) | 2016-09-06 | 2019-06-04 | 梅约医学教育与研究基金会 | 治疗表达pd-l1的癌症的方法 |
| CN110366563A (zh) * | 2016-12-22 | 2019-10-22 | 西奈山伊坎医学院 | 抗lilrb3抗体及其使用方法 |
| JP2024523885A (ja) * | 2021-06-15 | 2024-07-02 | ベイジン・シノタウ・バイオ－ファーマシューティカルズ・テクノロジー・カンパニー，リミテッド | 抗ｈｅｒ３抗体、それを含有する抗体薬物複合体及びそれらの用途 |
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| JP3040121B2 (ja) | 1988-01-12 | 2000-05-08 | ジェネンテク，インコーポレイテッド | 増殖因子レセプターの機能を阻害することにより腫瘍細胞を処置する方法 |
| PT896586E (pt) * | 1996-03-27 | 2007-01-31 | Genentech Inc | Anticorpos de erbb3 |
| AUPP380498A0 (en) | 1998-05-29 | 1998-06-25 | Biomolecular Research Institute Limited | Egf receptor agonists and antagonists |
| KR100945108B1 (ko) | 2001-06-13 | 2010-03-02 | 젠맵 에이/에스 | 표피 성장 인자 수용체 (ｅｇｆｒ)에 대한 인간모노클로날 항체 |
| EP1283053A1 (en) * | 2001-08-09 | 2003-02-12 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Inhibitors of HER3 activity |
| UA96139C2 (uk) | 2005-11-08 | 2011-10-10 | Дженентек, Інк. | Антитіло до нейропіліну-1 (nrp1) |
| AR056857A1 (es) | 2005-12-30 | 2007-10-24 | U3 Pharma Ag | Anticuerpos dirigidos hacia her-3 (receptor del factor de crecimiento epidérmico humano-3) y sus usos |
| KR101598229B1 (ko) | 2007-02-16 | 2016-02-26 | 메리맥 파마슈티컬즈, 인크. | Ｅｒｂｂ3에 대한 항체 및 이의 용도 |
| AU2009281721A1 (en) | 2008-08-15 | 2010-02-18 | Merrimack Pharmaceuticals, Inc. | Methods and systems for predicting response of cells to a therapeutic agent |
| CA2771744A1 (en) * | 2009-08-21 | 2011-02-24 | Merrimack Pharmaceuticals, Inc. | Antibodies against the ectodomain of erbb3 and uses thereof |
| PH12013500333A1 (en) * | 2010-08-20 | 2013-04-22 | Novartis Ag | Antibodies for epidermal growth factor receptor 3 (her3) |
| JP5995851B2 (ja) * | 2010-10-18 | 2016-09-21 | メディアファーマ エス． アール． エル．Ｍｅｄｉａｐｈａｒｍａ Ｓ． Ｒ． Ｌ． | ＥｒｂＢ３結合抗体 |
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2012
- 2012-11-09 WO PCT/US2012/064381 patent/WO2013071058A1/en not_active Ceased
- 2012-11-09 US US14/357,524 patent/US9637543B2/en not_active Expired - Fee Related
- 2012-11-09 JP JP2014541312A patent/JP6149042B2/ja not_active Expired - Fee Related
- 2012-11-09 CA CA2855298A patent/CA2855298A1/en not_active Abandoned
- 2012-11-09 AU AU2012335543A patent/AU2012335543C1/en not_active Ceased
- 2012-11-09 CN CN201280064525.0A patent/CN104011079B/zh not_active Expired - Fee Related
- 2012-11-09 EP EP12847223.0A patent/EP2788377B1/en not_active Not-in-force
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| CA2855298A1 (en) | 2013-05-16 |
| EP2788377B1 (en) | 2019-01-23 |
| WO2013071058A1 (en) | 2013-05-16 |
| AU2012335543A8 (en) | 2014-06-26 |
| EP2788377A1 (en) | 2014-10-15 |
| CN104011079B (zh) | 2017-06-16 |
| EP2788377A4 (en) | 2015-11-18 |
| JP2014533278A (ja) | 2014-12-11 |
| AU2012335543C1 (en) | 2017-12-14 |
| US9637543B2 (en) | 2017-05-02 |
| US20140314774A1 (en) | 2014-10-23 |
| AU2012335543B2 (en) | 2017-08-24 |
| CN104011079A (zh) | 2014-08-27 |
| AU2012335543A1 (en) | 2014-06-12 |
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