JP6143743B2 - 細胞におけるバイオマーカーの発現のクラスターによる解析 - Google Patents

細胞におけるバイオマーカーの発現のクラスターによる解析 Download PDF

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JP6143743B2
JP6143743B2 JP2014505670A JP2014505670A JP6143743B2 JP 6143743 B2 JP6143743 B2 JP 6143743B2 JP 2014505670 A JP2014505670 A JP 2014505670A JP 2014505670 A JP2014505670 A JP 2014505670A JP 6143743 B2 JP6143743 B2 JP 6143743B2
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cell
cluster
cells
association
expression
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JP2014517954A5 (enExample
JP2014517954A (ja
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マコラック，コリン・クレイグ
ジンティー，フィオナ
セヴィンスキー，クリストファー・ジェイムズ
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General Electric Co
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57434—Specifically defined cancers of prostate
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F18/00—Pattern recognition
    • G06F18/20—Analysing
    • G06F18/21—Design or setup of recognition systems or techniques; Extraction of features in feature space; Blind source separation
    • G06F18/211—Selection of the most significant subset of features
    • G06F18/2115—Selection of the most significant subset of features by evaluating different subsets according to an optimisation criterion, e.g. class separability, forward selection or backward elimination
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V10/00—Arrangements for image or video recognition or understanding
    • G06V10/70—Arrangements for image or video recognition or understanding using pattern recognition or machine learning
    • G06V10/77—Processing image or video features in feature spaces; using data integration or data reduction, e.g. principal component analysis [PCA] or independent component analysis [ICA] or self-organising maps [SOM]; Blind source separation
    • G06V10/771—Feature selection, e.g. selecting representative features from a multi-dimensional feature space
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00—Scenes; Scene-specific elements
    • G06V20/60—Type of objects
    • G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
    • G06V20/698—Matching; Classification
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/56—Staging of a disease; Further complications associated with the disease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis

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  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Theoretical Computer Science (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Evolutionary Computation (AREA)
  • Data Mining & Analysis (AREA)
  • Artificial Intelligence (AREA)
  • Multimedia (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Software Systems (AREA)
  • General Engineering & Computer Science (AREA)
  • Databases & Information Systems (AREA)
  • Hospice & Palliative Care (AREA)
  • Computing Systems (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Evolutionary Biology (AREA)
  • Medical Informatics (AREA)
  • Physiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Image Processing (AREA)
JP2014505670A 2011-04-22 2012-04-23 細胞におけるバイオマーカーの発現のクラスターによる解析 Active JP6143743B2 (ja)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US201161478224P 2011-04-22 2011-04-22
US61/478,224 2011-04-22
US13/252,072 2011-10-03
US13/252,078 US20120269419A1 (en) 2011-04-22 2011-10-03 Analyzing the expression of biomarkers in cells with moments
US13/252,072 US20120269418A1 (en) 2011-04-22 2011-10-03 Analyzing the expression of biomarkers in cells with clusters
US13/252,069 US20120270752A1 (en) 2011-04-22 2011-10-03 Analyzing the expression of biomarkers in cells with moments
US13/252,078 2011-10-03
US13/252,069 2011-10-03
US13/252,080 2011-10-03
US13/252,080 US20120271553A1 (en) 2011-04-22 2011-10-03 Analyzing the expression of biomarkers in cells with clusters
PCT/EP2012/057394 WO2012143561A2 (en) 2011-04-22 2012-04-23 Analyzing the expression of biomarkers in cells with clusters

Publications (3)

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JP2014517954A JP2014517954A (ja) 2014-07-24
JP2014517954A5 JP2014517954A5 (enExample) 2015-06-18
JP6143743B2 true JP6143743B2 (ja) 2017-06-07

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JP2014505670A Active JP6143743B2 (ja) 2011-04-22 2012-04-23 細胞におけるバイオマーカーの発現のクラスターによる解析
JP2014505669A Active JP6063446B2 (ja) 2011-04-22 2012-04-23 細胞におけるバイオマーカーの発現の積率による解析
JP2014505668A Active JP6163152B2 (ja) 2011-04-22 2012-04-23 細胞におけるバイオマーカーの発現の積率による解析
JP2014505671A Active JP6063447B2 (ja) 2011-04-22 2012-04-23 細胞におけるバイオマーカーの発現のクラスターによる解析

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JP2014505668A Active JP6163152B2 (ja) 2011-04-22 2012-04-23 細胞におけるバイオマーカーの発現の積率による解析
JP2014505671A Active JP6063447B2 (ja) 2011-04-22 2012-04-23 細胞におけるバイオマーカーの発現のクラスターによる解析

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US (5) US20120271553A1 (enExample)
EP (4) EP2700037A2 (enExample)
JP (4) JP6143743B2 (enExample)
BR (4) BR112013027124A2 (enExample)
CA (4) CA2833497A1 (enExample)
RU (3) RU2013145151A (enExample)
SG (4) SG194590A1 (enExample)
WO (4) WO2012143561A2 (enExample)

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Also Published As

Publication number Publication date
EP2700037A2 (en) 2014-02-26
BR112013027123A2 (pt) 2017-01-10
US20120271553A1 (en) 2012-10-25
CA2833804A1 (en) 2012-10-26
WO2012143556A3 (en) 2013-05-30
BR112013027125A2 (pt) 2017-01-10
JP6063446B2 (ja) 2017-01-18
CA2833497A1 (en) 2012-10-26
EP2700036A2 (en) 2014-02-26
RU2013145151A (ru) 2015-05-27
SG194592A1 (en) 2013-12-30
JP2014516413A (ja) 2014-07-10
WO2012143562A3 (en) 2013-02-28
US20120269419A1 (en) 2012-10-25
CA2833428A1 (en) 2012-10-26
CA2833295A1 (en) 2012-10-26
JP2014521926A (ja) 2014-08-28
WO2012143561A3 (en) 2013-05-23
JP6163152B2 (ja) 2017-07-12
US20120270752A1 (en) 2012-10-25
WO2012143558A3 (en) 2012-12-20
US20120269418A1 (en) 2012-10-25
SG194590A1 (en) 2013-12-30
EP2700042A2 (en) 2014-02-26
SG194594A1 (en) 2013-12-30
BR112013027122A2 (pt) 2017-01-10
EP2700042B1 (en) 2021-03-17
EP2700038B1 (en) 2021-04-21
EP2700038A2 (en) 2014-02-26
WO2012143562A2 (en) 2012-10-26
WO2012143556A2 (en) 2012-10-26
US20140185905A1 (en) 2014-07-03
RU2013145154A (ru) 2015-05-27
WO2012143558A2 (en) 2012-10-26
RU2013145162A (ru) 2015-05-27
JP2014521925A (ja) 2014-08-28
WO2012143561A2 (en) 2012-10-26
BR112013027124A2 (pt) 2017-01-10
JP6063447B2 (ja) 2017-01-18
JP2014517954A (ja) 2014-07-24
SG194588A1 (en) 2013-12-30

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