JP6143549B2 - Sample processing system - Google Patents

Description

  The present invention relates to a sample processing system.

  The sample processing system for automatically analyzing samples (for example, blood, urine, etc.) has been subjected to sample pretreatment that centrifuges, dispenses, and labels collected blood and urine, and this sample pretreatment Analyze the sample. In addition, since there are many types of these sample pretreatments and analysis processes, the sample processing system is configured so that a sample container containing a sample is placed via a sample transport line in order to perform each process with separate devices. Carry between.

  JP 2009-123178 A (Patent Document 1) states that “in a plurality of computers on a network, a configuration control server and a configuration control server that receives configuration control information from the configuration control server and that operates on its own computer. A network computer system is configured by a plurality of configuration control clients that execute processing based on information, and the configuration control server allows the computer on which the configuration control client operates to freely configure a screen server or a screen client, or change its settings. Build a screen sharing system that can do it. "

  Japanese Patent Laid-Open No. 11-223634 (Patent Document 2) discloses a “sample processing system including a sample transport unit that transports a sample and a plurality of sample processing units that process samples transported by the sample transport unit”. , A status monitoring screen that can identify a combination relationship between an operation unit that inputs operation information of the sample processing system, the sample processing unit with respect to the sample transport unit, and a display that can display an information display screen of the entire sample processing system The information processing device is configured to display information on the selected sample processing unit on the information display screen by selecting the sample processing unit on the state monitoring screen by operating the operation unit. . "

JP 2009-123178 A Japanese Patent Laid-Open No. 11-223634

  In the conventional sample processing system, each of the automatic analyzer and the sample pretreatment device has an operation unit, and the corresponding device can be controlled by operating each operation unit. Therefore, in order to control each apparatus, it is necessary to move to the operation part which controls an apparatus, and to operate, the work efficiency of the inspection engineer was reduced.

  An object of the present invention is to provide a sample processing system that eliminates the hassle of moving to and operating an operation unit that controls each device.

  Of the inventions disclosed in the present application, the outline of typical ones will be briefly described as follows.

  One embodiment of the present invention controls a sample pretreatment device for pretreatment of a sample, a sample analyzer for analyzing the sample pretreated by the sample pretreatment device, and the sample pretreatment device A sample processing system having a pretreatment device operation unit and an analysis device operation unit for controlling the sample analyzer, wherein the pretreatment device operation unit and the analysis device operation unit are Are connected to each other via a network. The pretreatment device operation unit and the analysis device operation unit may receive information input for controlling the sample pretreatment device or information for controlling the sample analysis device. The input of the information is accepted from any one of the input units for the analyzer that accepts the input, and the information that has been accepted is input to the operation unit for any preprocessing device or the operation unit for the analyzer via the network. To send.

  Among the inventions disclosed in the present application, effects obtained by typical ones will be briefly described as follows.

  According to an embodiment of the present invention, it is possible to eliminate the troublesomeness of moving to an operation unit that controls each device and operating the device.

It is a figure which shows the outline | summary of the structural example of the sample processing system in one embodiment of this invention. It is a figure which shows the outline | summary of the structural example of the sample processing system in one embodiment of this invention. In the sample processing system of FIG. 1, it is a figure which shows the example of the response screen displayed on the display part which an operation part has. In the sample processing system of FIG. 1, it is a figure which shows the example of the alarm screen displayed on the display part which an operation part has. In the sample processing system of FIG. 1, it is a figure which shows the example of the consumable goods display screen displayed on the display part which an operation part has. In the sample processing system of FIG. 1, it is a figure which shows the example of a screen transition of the response screen displayed on the display part which an operation part has. In the sample processing system of FIG. 1, it is a figure which shows the example of a screen transition of the response screen displayed on the display part which an operation part has. In the sample processing system of FIG. 1, it is a figure which shows the example of a screen transition of the response screen displayed on the display part which an operation part has. In the sample processing system of FIG. 1, it is a figure which shows the example of a screen transition of the response screen displayed on the display part which an operation part has.

  Hereinafter, embodiments of the present invention will be described in detail with reference to the drawings. Note that components having the same function are denoted by the same reference symbols throughout the drawings for describing the embodiment, and the repetitive description thereof will be omitted.

<System configuration>
1 and 2 show an outline of a configuration example of a sample processing system according to an embodiment of the present invention. In FIG. 1, the sample processing system includes, for example, sample pretreatment devices 10 and 20, biochemical analysis devices 30, 40, and 50, which are sample analysis devices, and an immune analysis device 60, sample pretreatment devices 10 and 20, and each sample It has a conveyance line 70 for connecting the analyzer, pretreatment device operation units 11, 21, and analysis device operation units 31, 41, 51, 61.

  In addition, the sample pretreatment devices 10, 20, biochemical analysis devices 30, 40, 50, immune analysis device 60, pretreatment device operation units 11, 21, and analysis device operation units 31, 41, 51, 61 include: Predetermined hardware and software are implemented. For example, the sample pretreatment devices 10, 20, biochemical analysis devices 30, 40, 50, immune analysis device 60, pretreatment device operation units 11, 21, and analysis device operation units 31, 41, 51, 61 are processors. The sample pretreatment devices 10 and 20, biochemical analysis devices 30, 40, and 50, the immunoassay device 60, and the operation for the pretreatment device are executed by executing the program on the memory by the processor. The computers of the units 11 and 21 and the analyzer operation units 31, 41, 51 and 61 are caused to function.

  The sample pretreatment device 10 includes a loading module, a centrifuge module, an unplugging module, an online dispensing module, a barcode attachment module, and a storage module.

  The sample pretreatment apparatus 20 includes a loading module, a centrifuge module, an opening module, an online dispensing module, a barcode attachment module, a closing module, a sample classification module, and a storage module.

  The biochemical analyzers 30, 40, and 50 and the immune analyzer 60 analyze the components of the specimen pretreated by the specimen pretreatment apparatuses 10 and 20.

  The conveyance line 70 conveys the sample from the sample pretreatment devices 10 and 20 to the biochemical analysis devices 30, 40, and 50 and the immune analysis device 60.

  The pretreatment device operation unit 11 is provided in the vicinity of the sample pretreatment device 10 and controls the sample pretreatment device 10. The pretreatment device operation unit 21 is provided in the vicinity of the sample pretreatment device 20 and controls the sample pretreatment device 20. The analyzer operation unit 31 is provided in the vicinity of the biochemical analyzer 30 and controls the biochemical analyzer 30. The analyzer operation unit 41 is provided in the vicinity of the biochemical analyzer 40 and controls the biochemical analyzer 40. The analyzer operation unit 51 is provided in the vicinity of the biochemical analyzer 50 and controls the biochemical analyzer 50. The analyzer operation unit 61 is provided in the vicinity of the immune analyzer 60 and controls the immune analyzer 60.

  The pretreatment device operation units 11 and 21 and the analysis device operation units 31, 41, 51, and 61 are a pretreatment device input unit that receives input of information for controlling the sample pretreatment devices 10 and 20. And an analyzer input unit that receives input of information for controlling the biochemical analyzers 30, 40, and 50 and the immune analyzer 60.

  The pretreatment device operation units 11 and 21 and the analysis device operation units 31, 41, 51, and 61 are provided at predetermined intervals (for example, 10 meters).

  When an abnormality occurs in any of the devices, the preprocessing device operation units 11 and 21 and the analysis device operation units 31, 41, 51, and 61 output sound from an output unit (not shown). The display unit 208 displays information indicating that an abnormality has occurred.

  When the pretreatment device operation units 11 and 21 and the analysis device operation units 31, 41, 51, 61 receive the measurement start input, the sample input from the input module of the sample pretreatment device 20 is opened with the centrifuge module. Sample preparation is performed by the stopper module and the dispensing module. The sample input from the input module is stored in the storage module, the sample that has been subjected to the sample pretreatment is transferred to the sample rack, and the sample rack is transported to the transport line 70.

  Next, the transport line 70 transports the sample rack storing the sample that has been subjected to the sample pretreatment to one of the biochemical analyzers 30, 40, and 50. This transport destination is determined by the sample pretreatment device 20 based on the inspection items of the sample. Thereafter, the biochemical analyzers 30, 40, 50 analyze the transported specimen.

  In FIG. 2, the sample processing system includes pretreatment device operation units 11 and 21 that control the sample pretreatment devices 10 and 20, biochemical analysis devices 30, 40, and 50, and analyzer operation that controls the immune analysis device 60. Parts 31, 41, 51, 61. The pretreatment device operation units 11 and 21 and the analysis device operation units 31, 41, 51, and 61 can communicate with each other via a communication collective repeater 80 (for example, HUB) via a network. Connected. As a result, the preprocessing device operation units 11 and 21 and the analysis device operation units 31, 41, 51, and 61 can communicate with each control target, and the preprocessing device operation units 11 and 21 and the analysis device Communication is possible between the operation units 31, 41, 51, 61, and the efficiency of work in the examination room can be improved.

  Here, the biochemical analyzers 40 and 50 measure the same items, and the specimens are alternately conveyed from the specimen pretreatment apparatus 20 to the biochemical analyzers 40 and 50. Then, after an abnormality occurs in the biochemical analyzer 50, the display of the display unit 208 of the analyzer operation unit 51 is switched to a screen that displays alarm information indicating the content of the abnormality. After confirming this alarm information, the inspection engineer performs recovery work of the biochemical analysis device 50. However, if it takes time to recover, the inspection engineer sets the biochemical analysis device 50 offline, and then performs biochemical analysis. It is necessary to stop the conveyance of the specimen to the apparatus 50.

  Conventionally, the laboratory technician who has confirmed the alarm information on the display unit 208 of the analyzer operation unit 51 has changed from the analyzer operation unit 51 of the biochemical analyzer 50 to the pretreatment device operation unit 21 of the sample pretreatment apparatus 20. The sample pretreatment device 20 is set so that the transport to the biochemical analysis device 50 is stopped and the sample is transported only to the biochemical analysis device 40 by operating the operation unit 21 for the pretreatment device. It was changed. The sample was transported from the sample pretreatment device 20 to the biochemical analysis device 50 while the laboratory technician moved, and the sample remained in the standby unit of the biochemical analysis device 50. In that case, the specimen staying in the standby section of the biochemical analyzer 50 had to be taken out manually by the laboratory technician and set in the biochemical analyzer 40.

  In the embodiment of the present invention, when the display unit 208 of the analyzer operation unit 51 is confirmed and it is determined that it takes time to restore, the analyzer operation unit 51 controls the biochemical analyzer 50. The input unit is switched from the analyzer input unit that receives input of information for performing the input to the preprocessor input unit that receives input of information for controlling the sample pretreatment device 20. Thereafter, when the analyzer operation unit 51 receives a predetermined input, the analyzer operation unit 51 stops the transport of the sample from the sample pretreatment device 20 to the biochemical analysis device 50 to the pretreatment device operation unit 21. A request to be transmitted is transmitted through the network. When the preprocessing device operation unit 21 receives a request from the analysis device operation unit 51, the preprocessing device operation unit 21 controls the sample pretreatment device 20 to stop the transport to the biochemical analysis device 50. Thereafter, when the analyzer operation unit 51 receives a predetermined input, the analyzer operation unit 51 requests the pretreatment device operation unit 21 to transport the sample from the sample pretreatment device 20 only to the biochemical analysis device 40. Are transmitted over the network. When receiving the request from the analyzer operation unit 51, the pretreatment device operation unit 21 controls the sample pretreatment device 20 so as to transport the sample only to the biochemical analysis device 40. As a result, the time required for movement in the examination room is omitted, the number of samples transported to the biochemical analyzer 50 is minimized, and back-end work such as manual work by the laboratory technician can be suppressed. This means that the entire laboratory system can be managed by a small number of people, and accurate situation confirmation and instructions are possible.

  Further, when an abnormality occurs in the biochemical analyzer 50, information indicating that the abnormality has occurred from the analyzer operating unit 51 is the preprocessing device operating units 11 and 21 and the analyzer operating units 31, 41, 51. 61, alarm information indicating that an abnormality has occurred is displayed on the display unit 208 of the preprocessing device operation units 11, 21 and the analysis device operation units 31, 41, 51, 61. Therefore, when an inspection engineer is present near the pretreatment device operation unit 21, the inspection engineer can confirm that an abnormality has occurred in the biochemical analysis device 50 without moving to the biochemical analysis device 50. Become. For example, in the case where the content of the abnormality that has occurred is not a serious abnormality that requires time to recover and the reagent of the biochemical analyzer 50 has been used up, the display unit 208 of the analyzer operation unit 51 is not checked. However, it can be confirmed from the display unit 208 of the preprocessing device operation unit 21 that an abnormality has occurred.

  In addition, information on the status of retesting in the biochemical analyzers 30, 40, and 50, which does not require treatment, and whether the urgently processed specimen is being centrifuged, unplugged, being dispensed, or being analyzed The processing status can be displayed on the display unit 208 of the preprocessing device operation units 11, 21 and the analysis device operation units 31, 41, 51, 61.

<Response screen>
FIG. 3 shows an example of a response screen displayed on the display unit 208 included in the pretreatment device operation units 11 and 21 and the analysis device operation units 31, 41, 51 and 61 in the sample processing system of FIG. 1. In FIG. 1, the display unit 208 included in the pretreatment device operation units 11 and 21 and the analysis device operation units 31, 41, 51, 61 includes an analysis device display switching button 201, an alarm display button 202, and an exhaustion. An item display button 203, a start button 204, a stop button 205, a power button 206, a process selection button 207, and a device image 209 are displayed.

  The device image 209 shows a device that is currently controlled. That is, in the response screen of FIG. 3, the image of the sample pretreatment device 20 is displayed on the display unit 208 as the device image 209, and the device currently controlled is the sample pretreatment device 20. Therefore, each button displayed on the display unit 208 functions as a preprocessing device input unit that receives input of information for controlling the sample preprocessing device 20.

  When the power button 206 accepts an operation, the power of the device to be controlled is turned on. When the power button 206 accepts an operation after the power is turned on, the device to be controlled is shut down. In the response screen of FIG. 3, when the power button 206 accepts an operation, the power supply of the sample pretreatment apparatus 20 is turned on. When the power button 206 receives an operation after the power is turned on, the sample pretreatment apparatus 20 is shut down.

  When the start button 204 accepts an operation, processing performed by the device to be controlled is started. Thereafter, when the stop button 205 accepts an operation, processing performed by the device that is the object of control is stopped. In the response screen of FIG. 3, when the start button 204 receives an operation, the sample pretreatment performed by the sample pretreatment device 20 is started. Thereafter, when the stop button 205 receives an operation, the sample pretreatment performed by the sample pretreatment device 20 is stopped.

  When the display switching button 201 receives an operation, the control target is switched, and the device image 209 of the control target device after the switching is displayed on the display unit 208.

  When the alarm display button 202 receives an operation, an alarm screen shown in FIG. 4 is displayed on the display unit 208. In the alarm screen of FIG. 4, the display unit 208 includes a display switching button 201, an alarm display button 202, a consumable display button 203, a start button 204, a stop button 205, a power button 206, A process selection button 207, alarm handling information 210, and alarm information 211 are displayed.

  The alarm information 211 corresponds to, for example, a sentence indicating that the reagent of the biochemical analyzer 30, 40, 50 has run out or a sentence indicating that the label of the sample pretreatment apparatus 10, 20 is cut.

  The alarm countermeasure information 210 expresses measures for resolving the warning content in text, and for example, texts explaining the reagent replacement procedure and texts explaining the label replacement procedure.

  By displaying the alarm information 211 and the alarm handling information 210 on the display unit 208, it becomes possible for the user to confirm the alarm warning content and the countermeasure method for the warning content. In addition, after confirming the alarm information 211 and the alarm countermeasure information 210, the display switching button 201 and the process selection button 207 accept operations from the user, so that the countermeasure according to the alarm information 211 and the alarm countermeasure information 210 becomes possible. .

  When the consumable item display button 203 accepts the operation, the display unit 208 displays a consumable item display screen shown in FIG. Here, on the consumable item display screen of FIG. 5, the display unit 208 displays the consumable item image 212 of the device to be controlled. The consumables include a bar code label of a bar code attachment module, which is a consumable used in the sample pretreatment apparatuses 10 and 20, a capping cap of a capping module of the sample pretreatment apparatus 20, and biochemical analysis apparatuses 30, 40, This corresponds to the remaining amount of 50 reagents and the dispensing tip. By checking the consumable image 212, the user can grasp consumables that need to be replenished for each device.

<Screen transition example>
6 to 9 show that the pretreatment device operation unit 21 receives the operation from the analysis device operation unit 51 provided in the vicinity of the biochemical analysis device 50 in the sample processing system of FIG. An example of screen transition when the sample transport destination is changed from the biochemical analyzer 50 to the biochemical analyzer 40 by controlling 20 is shown.

  First, in the response screen of FIG. 6, the biochemical analyzer 50 is displayed as the device image 209, and each button displayed on the display unit 208 accepts input of information for controlling the biochemical analyzer 50. Functions as an input unit for an analyzer. When the alarm display button 202 on the response screen in FIG. 6 accepts an operation, the display is switched to the alarm screen in FIG.

  In the alarm screen of FIG. 7, “reagent is out” is displayed as the alarm information 211, and “the sample pretreatment device is controlled after switching the display screen to change the transport destination to another biochemical analyzer as the alarm handling information 210. Please change to "is displayed. Thereafter, when the consumable item display button 203 on the response screen in FIG. 7 accepts an operation, the display is switched to the consumable item display screen in FIG.

  In the consumable item display screen of FIG. 8, the remaining amount of the reagent of the biochemical analyzer 50 is displayed as the consumable item image 212. Thereafter, when the display switching button 201 on the consumable item display screen in FIG. 8 receives the operation, the display is switched to the response screen in FIG. 9.

  In the response screen of FIG. 9, the sample pretreatment device 20 is displayed as the device image 209, and each button displayed on the display unit 208 is a preprocess that accepts input of information for controlling the sample pretreatment device 20. Functions as an input unit for the device. When the process selection button 207 on the response screen in FIG. 9 accepts input, the analyzer operation unit 51 transmits information corresponding to the accepted input to the preprocessing apparatus operation unit 21 via the network. Thereafter, the pretreatment device operation unit 21 controls the sample pretreatment device 20 based on the information received from the analysis device operation unit 51 to change the sample transport destination from the biochemical analysis device 50 to the biochemical analysis device 40. It is possible to deal with such as changing to.

<Effects of the present embodiment>
According to the sample processing system in the present embodiment described above, the preprocessing device operation units 11 and 21 and the analysis device operation units 31, 41, 51, and 61 are connected via a network so that they can communicate with each other. Information received from the input unit of either the preprocessing device input unit or the analysis device input unit is converted into any preprocessing device operation unit 11 or 21 or analysis device operation unit 31, 41, 51, 61. By transmitting to the network via the network, the time required for movement in the examination room can be omitted.

  In addition, by displaying the contents of the abnormality that has occurred in the preprocessing device operation units 11 and 21 and the analysis device operation units 31, 41, 51, and 61, the time required to move to the device in which the abnormality has occurred can be omitted. Become.

  Further, the pretreatment device operation units 11 and 21 and the analysis device operation units 31, 41, 51, 61 display an image indicating the degree of consumption of the consumables used in the sample pretreatment devices 10, 20. , It is possible to omit the time for moving to a device having a consumed consumable.

  In addition, the pretreatment apparatus operation units 11 and 21 and the analysis apparatus operation units 31, 41, 51, and 61 can display the status of the retest process and the sample processing in the sample pretreatment apparatuses 10 and 20. Become.

  In addition, the preprocessing device operation units 11 and 21 and the analysis device operation units 31, 41, 51, and 61 have a function of starting and stopping processing of an arbitrary device, so that the device that is desired to start or stop processing The time to move to can be omitted.

  In addition, the pretreatment device operation units 11 and 21 and the analysis device operation units 31, 41, 51, and 61 have a function of starting up a power source of any device and shutting down the power source. Time to move to the device you want to shut down can be omitted.

  A plurality of pretreatment device operation units 11 and 21 that control the sample pretreatment devices 10 and 20 are connected to each other via a network so that they can communicate with each other, and biochemical analysis devices 30 and 40 that are sample analysis devices. 50. A plurality of analyzer operation units 31, 41, 51, 61 for controlling the immune analyzer 60 are connected to each other via a network so that they can communicate with each other. Time can be omitted.

  As mentioned above, the invention made by the present inventor has been specifically described based on the embodiment. However, the present invention is not limited to the embodiment, and various modifications can be made without departing from the scope of the invention. Needless to say.

10, 20 Specimen pretreatment device 11, 21 Pretreatment device operation unit 30, 40, 50 Biochemical analysis device 31, 41, 51, 61 Analysis device operation unit 60 Immune analysis device 70 Transport line 80 Communication collective relay 201 Display switching button 202 Alarm display button 203 Consumables display button 204 Start button 205 Stop button 206 Power button 207 Process selection button 208 Display unit 209 Device image 210 Alarm handling information 211 Alarm information 212 Consumable image

Claims (7)

A sample pretreatment device for pretreating a sample, a sample analyzer for analyzing the sample pretreated by the sample pretreatment device, a pretreatment device operation unit for controlling the sample pretreatment device, A sample processing system having an analyzer operation unit for controlling the sample analyzer,
The pretreatment device operation unit and the analysis device operation unit are connected via a network so that they can communicate with each other.
The pretreatment device operation unit and the analysis device operation unit include a pretreatment device input unit that receives input of information for controlling the sample pretreatment device, and information for controlling the sample analysis device. Switch and display the analyzer input unit that accepts input ,
When the preprocessing device operation unit receives input of information for controlling the sample analyzer from the analyzer input unit, the information for controlling the sample analyzer is transmitted via the network. Sent to the analyzer operation unit,
When the analyzer operation unit receives input of information for controlling the sample pretreatment device from the pretreatment device input unit, information for controlling the sample pretreatment device is transmitted via the network. To the operation unit for the pretreatment device,
Sample processing system. The specimen processing system according to claim 1,
When an abnormality occurs in the sample pretreatment device or the sample analyzer,
The sample processing system, wherein the pretreatment device operation unit and the analysis device operation unit display alarm information indicating a content of an abnormality that has occurred. The sample processing system according to claim 1 or 2,
The sample processing system, wherein the pretreatment device operation unit and the analysis device operation unit display an image indicating a degree of consumption of a consumable used in the sample pretreatment device. In the sample processing system according to any one of claims 1 to 3,
The sample processing system, wherein the pretreatment device operation unit and the analysis device operation unit display a status of a retest process and a status of sample processing in the sample analyzer. In the sample processing system according to any one of claims 1 to 4,
The pretreatment device operation unit and the analysis device operation unit start processing performed by any of the sample pretreatment device and the sample analysis device, and perform the processing performed by the sample pretreatment device and the sample analysis device. A sample processing system having a function of stopping. In the sample processing system according to any one of claims 1 to 5,
The pretreatment device operation unit and the analysis device operation unit turn on the power supply of any of the sample pretreatment device and the sample analysis device, and shut down the power supply of the sample pretreatment device and the sample analysis device. A sample processing system having a function. In the sample processing system according to any one of claims 1 to 6,
The plurality of pretreatment device operation units that control the sample pretreatment device are connected to each other via a network so that they can communicate with each other, and the plurality of analysis device operation units that control the sample analysis device are mutually connected. A sample processing system that is communicably connected via a network.

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